Principal Investigators

Dr. Sofia Ahola is an Assistant Professor in the Department of Metabolism and Systems Science at the College of Medicine and Health. Sofia Ahola’s research group focuses on unravelling molecular mechanisms of mitochondrial diseases and their tissue specific fingerprints. We are especially interested in studying the stress responses and metabolic changes upon mitochondrial dysfunction ...

Dr Akerman is interested in answering fundamental questions about gene regulation in diseased and healthy pancreatic beta cells through integrated use of molecular, genomic, computational and systems biology. Her team aims to understand how various types of noncoding DNA elements interact to establish gene expression in the pancreatic beta cell. With the support of Diabetes UK, Akerman lab has ...

John Allotey is Associate Professor in Epidemiology and Women’s Health at the WHO Collaborating Centre for Global Women's Health within the Department of Metabolism and Systems Science. He has almost a decade of experience in academic clinical research, primarily in the field of maternal health. His research interests lie in the development, evaluation and implementation of ...

Davide Calebiro is the Head of the Department of Metabolism and Systems Science, a Professor of Molecular Endocrinology, Wellcome Trust Senior Research Fellow and Co-Director of the Centre of Membrane Proteins and Receptors (COMPARE) of the Universities of Birmingham and Nottingham

He leads a multidisciplinary research team comprising biologists, chemists, physicists, engineers and computer ...

Sarah Conner is a Senior Lecturer in Reproductive Biology and an Honorary Research Scientist at the Birmingham Women’s Fertility Centre.

In addition to her research interests, Sarah is an enthusiastic contributor to and coordinator of Reproduction teaching across a number of undergraduate programmes in the University.

Professor Coomarasamy is the Director of Tommy’s National Centre for Miscarriage Care and Research. His research interests are in fertility, early pregnancy and global women’s health.

Gaby is an Associate Professor in Cellular Metabolism and a Senior Fellow of the Higher Education Academy.  An expert in pancreatic islet biology, she is interested in energy homeostasis, particularly in fuel sensing mechanisms that may play a role in diabetes and obesity.  She is currently also studying mechanisms behind some rare metabolic conditions. She is a team member of the NIHR ...

Adam's primary research focus is clinical trials in early pregnancy care, with a particular focus on miscarriage, infertility and global women’s health. As Associate Professor of Maternal Health Clinical Trials, he collaborates with the Birmingham Clinical Trials Unit to manage a portfolio of national and international clinical trials. He is also a senior consortium member of the Tommy' ...

Vivek Dhir is a Senior Lecturer in Molecular Endocrinology and has published a number of high impact research papers in scientific journals as well as reviews in the fields of endocrinology, metabolism and genetics. He has received major grants from the Welcome trust and The MRC.

Vivek is keen to talk about his science and gives frequent seminars to various groups at the local, national and ...

Sarah Dimeloe is an Associate Professor working across the Departments of Immunology and Immunotherapy, and Metabolism and Systems Science.

Research in Sarah’s lab is focused on the metabolism of immune cells and how this underpins their role in health and disease.

 

Dr Dutta is a distinguished biomedical engineer and entrepreneur whose global career bridges academia and industry, significantly advancing neuroengineering for neurorehabilitation. He earned his Bachelor of Engineering from Jadavpur University in India, followed by an M.S. from the University of Florida and a Ph.D. from Case Western Reserve University in the USA. Further enhancing his expertise, ...

Dr Foster is an established research figure in the fields of endocrinology, cancer and drug discovery. With over two decades of experience in both academic and industrial environments, he has extensive research knowledge on a wide-range of areas. He is an author on over 55 scientific peer-reviewed papers, covering endocrinology, oncology, inflammation, cardiology, and drug development, and has ...

Dr Gallagher's research interests are in: image analysis of human sperm motility; Biological fluid dynamics; Asymptotic and numerical methods to investigate problems in fluid mechanics; Mathematical modelling of fluid structure interaction; Numerical modelling of stability of Non-Newtonian fluids.

Caroline Gillett is the Assistant Professor in Patient and Public Involvement and Engagement in the Department of Metabolism and Systems Science. She manages the Department's Public and Patient Engagement and Involvement Strategy, including devising and delivering activities, training and events to engage diverse communities with the Department's highly societally relevant research portfolio.

She ...

Professor Neil Gittoes is Consultant Endocrinologist at the Queen Elizabeth Hospital, Birmingham and Honorary Professor of Endocrinology at the University of Birmingham. He is inaugural Head of the Centre of Endocrinology, Diabetes and Metabolism (CEDAM), a partnership organisation across NHS provider organisations and the University of Birmingham aiming to optimise translational research ...

Caroline’s research is focussed on the trafficking and signalling of membrane proteins, and how their impairments contribute to endocrine and metabolic disease. Her research group investigates the fundamental mechanisms by which G protein-coupled receptors signal to regulate appetite, bone metabolism and calcium homeostasis. 

As an Associate Professor in Steroid Metabolism and Signalling I have expanded upon a successful Versus Arthritis Early Career Development fellowship to become a leader in the field of steroid metabolism and inflammation and in vivo models of chronic inflammation. My research group is examining the roles of myeloid and mesenchymal steroid metabolism and signalling in mediating inflammatory ...

Martin’s group investigates the role vitamin D  plays in human health beyond its effects on bone. They focus on vitamin D and immune function, and how this influences infectious diseases, pregnancy and autoimmune disease.

Jan is Clinical Associate Professor in Paediatric Endocrinology and Diabetes, based at Metabolism and Systems Science (MSS) and at the Department of Endocrinology at the Birmingham Children’s Hospital.

Jan is Programme Director of the Welcome Trust/ NIHR Clinical Research Facility(Paediatrics) and he also leads the West Midlands Childhood Obesity (Complications of Excess Weight, CEW) ...

Dr. Leandro Junges is a Centre Fellow at the Centre for Systems Modelling and Quantitative Biomedicine (SMQB). His research focuses on the development and application of mathematical and computational methods to help understanding biomedical systems and develop personalised predictions in healthcare, especially in the context of neuroscience.

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Niki Karavitaki is Professor of Endocrinology and Honorary Consultant Endocrinologist at the Queen Elizabeth Hospital Birmingham where she co-leads the Pituitary Service and Pituitary MDT.

Her research and clinical interests focus on hypothalamo-pituitary disease (particularly sellar and parasellar tumours and hypopituitarism) covering pathogenesis, management and long-term outcomes and ...

Jackson’s research is about andrology and its application in the diagnosis and treatment of infertility, with direct impact on care and quality of life of the patients involved and the birth of the next generation. 

Christian’s research is focused on developing novel experimental and analytical approaches to map metabolic pathway activities without assuming a particular metabolism model.

Dr Maria Makarova is a Group leader at the Department of Metabolism and Systems Science (MSS) at College of Medicine and Health. Her research is focussed on the chemical biology of lipid metabolism, linking genetics and membrane biophysics with applications in evolution, cell physiology, and industrial microbiology.

Chris McCabe is Professor of Molecular Endocrinology at the University of Birmingham. He works on mechanisms of endocrine cancers, including thyroid and breast tumour models. Specifically, the research of the McCabe group focuses on the action of the sodium iodide symporter NIS in thyroid tumours; assessment of the role of the proto-oncogenes PTTG and PBF in thyroid and breast; in vitro and in ...

Dr Mueller’s research aims for an understanding of the structure and function of proteins. Jon’s major interest is in enzyme-catalysed reactions that modulate hormone function, switching hormone action on or off. The dynamic sulfation and de-sulfation of steroid hormones is one of these switches. Dr Mueller’s research group studies sulfation pathways, using bioinformatics as ...

Professor Manfred Opper is interested in the development and the theoretical analysis of methods for probabilistic inference in machine learning using techniques of statistical mechanics and statistics. In recent years he has worked especially in the area of data assimilation, where he has developed approximations for inference in stochastic differential equations, Markov jump processes and ...

Dr Alessandro Prete completed his training in Endocrinology and Diabetes in Rome, Italy. In 2016, he joined the Institute of Metabolism and Systems Research at the University of Birmingham. Since 2018, he is a Diabetes UK Sir George Alberti Research Fellow and is currently working towards a PhD. The title of his PhD thesis is "Exploring the metabolic impact of mild autonomous cortisol excess ...

Cristina Ronchi is a clinician scientist with long-standing translational expertise in endocrine tumors. Her research field mostly focuses on mechanisms involved in the pathogenesis of adrenal tumours, as well as prognostic biomarkers and novel drug targets for adrenocortical cancer.  She is particularly active in research dissemination and collaborates with several world-leading groups ...

Nadia Schoenmakers is a clinician-scientist who investigates  the causes and consequences of a broad range of thyroid disorders. Her research particularly focuses on rare diseases such as congenital hypothyroidism (CH), for which she aims to delineate the genetic basis, and to determine the associated phenotypes. In the laboratory, she seeks to understand the role of known and novel genes in ...

Dr Atif Shahzad is Assistant Professor of Medical Technologies and Programme Lead for MSc Biomedical Innovation program at the Department of Metabolism and Systems Science, University of Birmingham. He is associated with the Centre for Systems Modelling and Quantitative Biomedicineand also holds an honorary position at the University of Galway. Atif is interested in needs-led health technology ...

 

 

Vicki is interested in thyroid biology and the molecular pathogenesis of thyroid disease. Her research focuses on improving existing treatments and identifying novel therapies in thyroid cancer.

Professor Daniel Tennant is a Professor of Biochemistry in the Department of Metabolism and Systems Science, situated on the second floor of the Institute of Biomedical Research. He uses stable isotope tracers to investigate changes in the use of nutrients in conditions where oxygen is limiting (hypoxia), or in the presence of genetic mutations that induce a hypoxia-like response. Dan applies the ...

Professor John Terry is Interdisciplinary Professorial Fellow: a post he holds jointly across Mathematics, Computer Science and the Department for Metabolism and Systems Science. John is also the recipient of a prestigious EPSRC Established Career Fellowship, as well as being an EPSRC Public Engagement Championwithin Computer Science. John’s research transcends traditional discipline ...

Professor Shakila Thangaratinam is Honorary Professor at the University of Birmingham. As Consultant Obstetrician she is involved in the care of high-risk mothers at Birmingham Women’s and Children’s NHS Foundation Trust.

In her previous role as Professor at Queen Mary University of London (2012-2019), Professor Thangaratinam established the Barts Research Centre for ...

Dr Wakerley is a leading consultant neurologist and expert in headache. He is also an Honorary Senior Clinical Lecturer at the Department of Metabolism and Systems Science (MSS).

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Professor Zamora has developed an academic career at the University of Madrid in the Biomathematics department as an Associate Professor of Biostatistics. He has been appointed as Non-Clinical Senior Lecturer of Perinatal statistics in BARC (Barts Research Centre for Women’s Health) in Queen Mary University of London.

Professor Zamora has an outstanding track record of delivering ...

Dr Eder Zavala is an applied mathematician jointly appointed across the School of Mathematics, Computer Science, and the College of Medicine and Health. His work focuses on interdisciplinary research spanning mathematics, computational and biomedical sciences. Eder has held an MRC Skills Development Fellowship and a EU Horizon 2020 secondment to develop quantitative methods for the diagnosis and ...