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Article
Ahola, S, Pazurek, LA, Mayer, F, Lampe, P, Hermans, S, Becker, L, Amarie, OV, Fuchs, H, Gailus-Durner, V, Angelis, MHD, Riedel, D, Nolte, H & Langer, T 2024, 'Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy', Science Advances, vol. 10, no. 31, eadp0443. https://doi.org/10.1126/sciadv.adp0443
Rivera-Mejías, P, Narbona-Pérez, ÁJ, Hasberg, L, Kroczek, L, Bahat, A, Lawo, S, Folz-Donahue, K, Schumacher, A-L, Ahola, S, Mayer, FC, Giavalisco, P, Nolte, H, Lavandero, S & Langer, T 2023, 'The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage', Cell Reports, vol. 42, no. 4, 112332. https://doi.org/10.1016/j.celrep.2023.112332
Ahola, S, Rivera mejías, P, Hermans, S, Chandragiri, S, Giavalisco, P, Nolte, H & Langer, T 2022, 'OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy', Cell Metabolism, vol. 34, no. 11, pp. 1875-1891.e7. https://doi.org/10.1016/j.cmet.2022.08.017
Sprenger, HG, Wani, G, Hesseling, A, König, T, Patron, M, MacVicar, T, Ahola, S, Wai, T, Barth, E, Rugarli, EI, Bergami, M & Langer, T 2019, 'Loss of the mitochondrial iii-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.', EMBO Molecular Medicine. https://doi.org/10.15252/emmm.201809288
Buzkova, J, Nikkanen, J, Ahola, S, Hakonen, AH, Sevastianova, K, Hovinen, T, Yki-Järvinen, H, Pietiläinen, K, Lönnqvist, T, Velagapudi, V, Carroll, C & Suomalainen, A 2018, 'Metabolomes of mitochondrial diseases and inclusion body myositis patients: treatment targets and biomarkers.', EMBO Molecular Medicine. https://doi.org/10.15252/emmm.201809091
Nikkanen, J, Forsström, S, Euro, L, Paetau, I, Kohnz, RA, Wang, L, Chilov, D, Viinamäki, J, Roivainen, A, Marjamäki, P, Liljenbäck, H, Ahola, S, Buzkova, J & Suomalainen, A 2016, 'Mitochondrial DNA Replication Defects Disturb Cellular dNTP Pools and Remodel One-Carbon Metabolism.', Cell Metabolism. https://doi.org/10.1016/j.cmet.2016.01.019
Ahola, S, Auranen, M, Isohanni, P, Niemisalo, S, Urho, N, Buzkova, J, Velagapudi, V, Lundbom, N, Hakkarainen, A, Muurinen, T, Piirilä, P, Pietiläinen, KH & Suomalainen, A 2016, 'Modified Atkins diet induces subacute selective ragged-red-fiber lysis in mitochondrial myopathy patients.', EMBO Molecular Medicine. https://doi.org/10.15252/emmm.201606592
Ahlqvist, KJ, Leoncini, S, Pecorelli, A, Wortmann, SB, Ahola, S, Forsström, S, Guerranti, R, De, FC, Smeitink, J, Ciccoli, L, Hämäläinen, RH & Suomalainen, A 2015, 'MtDNA mutagenesis impairs elimination of mitochondria during erythroid maturation leading to enhanced erythrocyte destruction.', Nature Communications. https://doi.org/10.1038/ncomms7494
Ahola, S, Isohanni, P, Euro, L, Brilhante, V, Palotie, A, Pihko, H, Lönnqvist, T, Lehtonen, T, Laine, J, Tyynismaa, H & Suomalainen, A 2014, 'Mitochondrial EFTs defects in juvenile-onset Leigh disease, ataxia, neuropathy, and optic atrophy.', Neurology. https://doi.org/10.1212/WNL.0000000000000716
Guse, K, Suzuki, M, Sule, G, Bertin, TK, Tyynismaa, H, Ahola-Erkkilä, S, Palmer, D, Suomalainen, A, Ng, P, Cerullo, V, Hemminki, A & Lee, B 2012, 'Capsid-modified adenoviral vectors for improved muscle-directed gene therapy', Human Gene Therapy, vol. 23, no. 10, pp. 1065-1070. https://doi.org/10.1089/hum.2012.003
Tyynismaa, H, Sun, R, Ahola-Erkkilä, S, Almusa, H, Pöyhönen, R, Korpela, M, Honkaniemi, J, Isohanni, P, Paetau, A, Wang, L & Suomalainen, A 2012, 'Thymidine kinase 2 mutations in autosomal recessive progressive external ophthalmoplegia with multiple mitochondrial DNA deletions', Human Molecular Genetics, vol. 21, no. 1, pp. 66-75. https://doi.org/10.1093/hmg/ddr438
Ahola, SA-E, Carroll, CJ, Peltola-Mjösund, K, Tulkki, V, Mattila, I, Seppänen-Laakso, T, Orešič, M, Tyynismaa, H & Suomalainen, A 2010, 'Ketogenic diet slows down mitochondrial myopathy progression in mice', Human Molecular Genetics, vol. 19, no. 10, pp. 1974–1984. https://doi.org/10.1093/hmg/ddq076
Editorial
Ahola, S 2024, 'Editorial: Mitochondrial bioenergetics and metabolism: implication for human health and disease', Frontiers in Molecular Biosciences, vol. 11, 1468758. https://doi.org/10.3389/fmolb.2024.1468758
Other contribution
Ahola, S, Langer, T & MacVicar, T 2019, Mitochondrial Proteolysis and Metabolic Control.. https://doi.org/10.1101/cshperspect.a033936
Review article
Ahola, S & Langer, T 2024, 'Ferroptosis in mitochondrial cardiomyopathy', Trends in Cell Biology, vol. 34, no. 2, pp. 150-160. https://doi.org/10.1016/j.tcb.2023.06.002
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