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Rare antibodies (IgG)
Similar staining pattern as anti-Hu antibody
Antibody binds to CNS but not PNS neurones (myenteric neurones stain negative)
A high intensity signal at both 55 and 80 kDa on a Western blot would confirm Ri specificity.
Neurological syndrome: Cerebellar degeneration, opsoclonus/myclonus
Associated tumours: Breast, gynaecological and small cell lung carcinoma |