Hu antibody
Cerebellum | Rodent stomach |
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Hu antibody binds to the granular and Purkinje neurones. |
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Anti-Hu antibody staining myenteric plexus. |
This is the most commonly occurring paraneoplastic neurological antibody.
Neurological syndrome: Cerebellar ataxia, encephalomyelitis, sensory neuropathy
Associated tumour: Small cell lung carcinoma and neuroblastoma