The UltramicroscopeII is a fluorescent microscope used for 3D imaging of optically-cleared samples such as whole mouse organs and small tissue samples (essentially 3-D histology).
It is best suited for visualizing whole biological systems with cellular resolution.
The system uses six light sheets in a dual-sided arrangement for homogeneous illumination, with the detection objective perpendicular to laser illumination.
Microscope Details
- Sample size: whole organs, large tissue, embryos, etc (< 1cm3)
- Main application: 3D imaging of whole biological systems
- Modalities: uni and bi-directional imaging with variable sheet width
- Spatial Resolution: cellular
- Environmental control: N/A
- Excitation Lasers: 488, 561, 640 and 780 nm