The Steroid Metabolome Analysis Core (SMAC)
Article
Schiffer, L, Kempegowda, P, Sitch, AJ, Adaway, JE, Shaheen, F, Ebbehoj, A, Singh, S, Mctaggart, MP, O’reilly, MW, Prete, A, Hawley, JM, Keevil, BG, Bancos, I, Taylor, AE & Arlt, W 2023, 'Classic and 11-oxygenated androgens in serum and saliva across adulthood: a cross-sectional study analyzing the impact of age, body mass index, and diurnal and menstrual cycle variation', European Journal of Endocrinology, vol. 188, no. 1, lvac017. https://doi.org/10.1093/ejendo/lvac017
Bentley, C, Hazeldine, J, Bravo, L, Taylor, AE, Gilligan, LC, Shaheen, F, Acharjee, A, Gkoutos, G, Foster, MA, Arlt, W & Lord, JM 2023, 'The ultra-acute steroid response to traumatic injury: a cohort study', European Journal of Endocrinology. https://doi.org/10.1093/ejendo/lvad024
Prete, A, Taylor, A & Brown, MJ 2023, '[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial', Nature Medicine, vol. 29, no. 1, pp. 190-202. https://doi.org/10.1038/s41591-022-02114-5
Moll, JM, Hofland, J, Teubel, W, Ridder, CMAD, Taylor, A, Graeser, R, Arlt, W, Jenster, G & Van Weerden, W 2022, 'Abiraterone switches castration‐resistant prostate cancer dependency from adrenal androgens towards androgen receptor variants and glucocorticoid receptor signalling', The Prostate, vol. 82, no. 5, pp. 505-516. https://doi.org/10.1002/pros.24297
Prete, A, Subramanian, A, Bancos, I, Chortis, V, Tsagarakis, S, Lang, K, Macech, M, Delivanis, D, Pupovac, I, Reimondo, G, Marina, L, Deutschbein, T, Balomenaki, M, O'reilly, M, Gilligan, L, Jenkinson, C, Bednarczuk, T, Zhang, C, Dusek, T, Diamantopoulos, A, Asia, M, Kondracka, A, Li, D, Masjkur, J, Quinkler, M, Ueland, G, Dennedy, C, Beuschlein, F, Tabarin, A, Fassnacht, M, Ivovic, M, Terzolo, M, Kastelan, D, Young Jr, W, Manolopoulos, K, Ambroziak, U, Vassiliadi, D, Taylor, A, Sitch, A, Nirantharakumar, K & Arlt, W 2022, 'Cardiometabolic disease burden and steroid excretion in benign adrenal tumors: a cross-sectional multicenter study', Annals of internal medicine, vol. 175, no. 3, pp. 325-334. https://doi.org/10.7326/M21-1737
Schiffer, L, Shaheen, F, Gilligan, LC, Storbeck, K-H, Hawley, JM, Keevil, BG, Arlt, W & Taylor, AE 2022, 'Multi-steroid profiling by UHPLC-MS/MS with post-column infusion of ammonium fluoride', Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, vol. 1209, 123413. https://doi.org/10.1016/j.jchromb.2022.123413
Snaterse, G, Van Dessel, L, Riet, JV, Taylor, A, Vlugt-Daane, MVD, Hamberg, P, Wit, PRD, Visser, JA, Arlt, W, Lolkema, M & Hofland, J 2021, '11-Ketotestosterone is the predominant active androgen in prostate cancer patients after castration: the resilience of a potent androgen in prostate cancer patients after castration', JCI Insight, vol. 6, no. 11, e148507. https://doi.org/10.1172/jci.insight.148507
Bentley, C, Potter, C, Yakoub, KM, Brock, K, Homer, V, Toman, E, Taylor, AE, Shaheen, F, Gilligan, LC, Athwal, A, Barton, D, Carrera, R, Young, K, Desai, A, McGee, K, Ermogenous, C, Sur, G, Greig, CA, Hazeldine, J, Arlt, W, Lord, JM & Foster, MA 2021, 'A prospective, phase II, single-centre, cross-sectional, randomised study investigating Dehydroepiandrosterone supplementation and its Profile in Trauma: ADaPT', BMJ open, vol. 11, no. 7, e040823. https://doi.org/10.1136/bmjopen-2020-040823
Grech, O, Clouter, A, Mitchell, J, Alimajstorovic, Z, Ottridge, R, Yiangou, A, Roque, M, Tahrani, A, Nicholls, M, Taylor, A, Shaheen, F, Arlt, W, Lavery, G, Shapiro, K, Mollan, S & Sinclair, A 2021, 'Cognitive performance in idiopathic intracranial hypertension and relevance of intracranial pressure', Brain Communications, vol. 3, no. 3, fcab202. https://doi.org/10.1093/braincomms/fcab202
Taiwo, BG, Frettsome-Hook, RL, Taylor, AE, Correia, JN, Lefievre, L, Publicover, SJ, Conner, SJ & Kirkman-Brown, JC 2021, 'Complex combined steroid mix of the female tract modulates human sperm', Reproductive biology, vol. 21, no. 4, 100561. https://doi.org/10.1016/j.repbio.2021.100561
Fenton, C, Martin, C, Jones, R, Croft, A, Campos, J, Naylor, A, Taylor, A, Chimen, M, Cooper, M, Lavery, G, Raza, K & Hardy, R 2021, 'Local steroid activation is a critical mediator of the anti-inflammatory actions of therapeutic glucocorticoids', Annals of the Rheumatic Diseases, vol. 80, no. 2, pp. 250-260. https://doi.org/10.1136/annrheumdis-2020-218493
Schiffer, L, Bossey, A, Kempegowda, P, Taylor, A, Akerman, I, Scheel-Toellner, D, Storbeck, K-H & Arlt, W 2021, 'Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens', European Journal of Endocrinology, vol. 184, no. 3, pp. 353–363. https://doi.org/10.1530/EJE-20-1077
Prete, A, Taylor, AE, Bancos, I, Smith, DJ, Foster, MA, Kohler, S, Fazal-Sanderson, V, Komninos, J, O'Neil, DM, Vassiliadi, DA, Mowatt, CJ, Mihai, R, Fallowfield, JL, Annane, D, Lord, JM, Keevil, BG, Wass, JAH, Karavitaki, N & Arlt, W 2021, 'Response to Letter to the Editor from Chee et al: "Prevention of Adrenal Crisis: Cortisol Response to Major Stress Compared to Stress Dose Hydrocortisone Delivery"', The Journal of clinical endocrinology and metabolism, vol. 106, no. 1, pp. e407-e408. https://doi.org/10.1210/clinem/dgaa719
Comment/debate
Chortis, V, Sitch, AJ, Bancos, I, Prete, A, Taylor, AE, Biehl, M, Deeks, JJ & Arlt, W 2021, 'Comment on "A Modern Assessment of Cancer Risk in Adrenal Incidentalomas: Analysis of 2219 Patients" by Kahramangil B et al', Annals of surgery, vol. 274, no. 6, pp. e887-e888. https://doi.org/10.1097/SLA.0000000000004804
Review article
Hardy, R, Botfield, H, Markey, K, Mitchell, J, Alimajstorovic, Z, Westgate, C, Sagmeister, M, Fairclough, R, Ottridge, R, Yiangou, A, Storbeck, K-H, Taylor, A, Gilligan, L, Arlt, W, Stewart, P, Tomlinson, J, Mollan, S, Lavery, G & Sinclair, A 2021, '11βHSD1 inhibition with AZD4017 improves lipid profiles and lean muscle mass in Idiopathic intracranial hypertension', Journal of Clinical Endocrinology and Metabolism, vol. 106, no. 1, pp. 174-187. https://doi.org/10.1210/clinem/dgaa766