Publications

Publications from Centre members.

2021

Andelic N, Røe C, Brunborg C, Zeldovich M, Løvstad M, Løke D, Borgen IM, Voormolen DC, Howe EI, Forslund MV, Dahl HM, von Steinbuechel N; CENTER-TBI participants investigators. Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study. J Neurol. 2021 Jan;268(1):61-73. doi: 10.1007/s00415-020-10022-2.

Althobaiti S, Rushton A, Falla D, Heneghan NR. Measures of trunk muscle strength and their measurement properties: a protocol for a systematic review and narrative synthesis of clinical measures. BMJ Open. 2021 Jan 7;11(1):e041499. doi: 10.1136/bmjopen-2020-041499.

Apampa AA, Ali A, Kadir B, Ahmed Z. Safety and effectiveness of surgical fixation versus non-surgical methods for the treatment of flail chest in adult populations: a systematic review and meta-analysis. Eur J Trauma Emerg Surg. 2021 Feb 6:1-10. doi: 10.1007/s00068-021-01606-2.

Arvanitidis M, Falla D, Sanderson A, Martinez-Valdes E. Does pain influence force steadiness? A protocol for a systematic review. BMJ Open. 2021 Jan 8;11(1):e042525. doi: 10.1136/bmjopen-2020-042525.

Bentley C, Cooper L, Foster M, Fallowfield J. Reflecting on success in trauma research: experiences from the SGCNS and SIR studies. BMJ Mil Health. 2021 Apr;167(2):118-121. doi: 10.1136/bmjmilitary-2020-001467.

Bentley C, Potter C, Yakoub KM, Brock K, Homer V, Toman E, Taylor AE, Shaheen F, Gilligan LC, Athwal A, Barton D, Carrera R, Young K, Desai A, McGee K, Ermogenous C, Sur G, Greig CA, Hazeldine J, Arlt W, Lord JM, Foster MA. A prospective, phase II, single-centre, cross-sectional, randomised study investigating Dehydroepiandrosterone supplementation and its Profile in Trauma: ADaPT. BMJ Open. 2021 Jul 26;11(7):e040823. doi: 10.1136/bmjopen-2020-040823.

Blanch RJ, Mazzoli RA, Porter K. Ophthalmic Injuries in the Port Explosion in Beirut, Lebanon: Lessons for Provision of Ophthalmic Trauma Care and Major Incident Management. JAMA Ophthalmol. 2021 Aug 5. doi: 10.1001/jamaophthalmol.2021.2707.

Böhm JK, Güting H, Thorn S, Schäfer N, Rambach V, Schöchl H, Grottke O, Rossaint R, Stanworth S, Curry N, Lefering R, Maegele M; CENTER-TBI Participants and Investigators. Global Characterisation of Coagulopathy in Isolated Traumatic Brain Injury (iTBI): A CENTER-TBI Analysis. Neurocrit Care. 2021 Aug;35(1):184-196. doi: 10.1007/s12028-020-01151-7.

Citerio G, Robba C, Rebora P, Petrosino M, Rossi E, Malgeri L, Stocchetti N, Galimberti S, Menon DK; Center-TBI participants and investigators. Management of arterial partial pressure of carbon dioxide in the first week after traumatic brain injury: results from the CENTER-TBI study. Intensive Care Med. 2021 Jul 24:1-13. doi: 10.1007/s00134-021-06470-7.

CRASH-3 Intracranial Bleeding Mechanistic Study Collaborators. Tranexamic acid in traumatic brain injury: an explanatory study nested within the CRASH-3 trial. Eur J Trauma Emerg Surg. 2021 Feb;47(1):261-268. doi: 10.1007/s00068-020-01316-1.

Dijkland SA, Helmrich IRAR, Nieboer D, van der Jagt M, Dippel DWJ, Menon DK, Stocchetti N, Maas AIR, Lingsma HF, Steyerberg EW; CENTER-TBI Participants and Investigators. Outcome Prediction after Moderate and Severe Traumatic Brain Injury: External Validation of Two Established Prognostic Models in 1742 European Patients. J Neurotrauma. 2021 May 15;38(10):1377-1388. doi: 10.1089/neu.2020.7300.

Forcione M, Ganau M, Prisco L, Chiarelli AM, Bellelli A, Belli A, Davies DJ. Mismatch between Tissue Partial Oxygen Pressure and Near-Infrared Spectroscopy Neuromonitoring of Tissue Respiration in Acute Brain Trauma: The Rationale for Implementing a Multimodal Monitoring Strategy. Int J Mol Sci. 2021 Jan 23;22(3):1122. doi: 10.3390/ijms22031122.

Fountain DM, Henry J, Honeyman S, O'Connor P, Sekhon P, Piper RJ, Edlmann E, Martin M, Whiting G, Turner C, Mee H, Joannides AJ, Kolias AG, Hutchinson PJ; UK Cranial Reconstruction Registry (UKCRR) Collaborative; British Neurosurgical Trainee Research Collaborative (BNTRC). First Report of a Multicenter Prospective Registry of Cranioplasty in the United Kingdom and Ireland. Neurosurgery. 2021 Jun 30:nyab220. doi: 10.1093/neuros/nyab220.

Gensheimer WG, Kerber MT, Blanch RJ. The epidemiology and outcomes of combat ocular trauma among local nationals managed at a deployed military hospital in Afghanistan. Eye (Lond). 2021 Aug;35(8):2155-2163. doi: 10.1038/s41433-020-01316-w.

Gravesteijn BY, Sewalt CA, Venema E, Nieboer D, Steyerberg EW; CENTER-TBI Collaborators.Missing Data in Prediction Research: A Five-Step Approach for Multiple Imputation, Illustrated in the CENTER-TBI Study. J Neurotrauma. 2021 Jun 1;38(13):1842-1857. doi: 10.1089/neu.2020.7218.

Glendon K, Blenkinsop G, Belli A, Pain M. Does Vestibular-Ocular-Motor (VOM) Impairment Affect Time to Return to Play, Symptom Severity, Neurocognition and Academic Ability in Student-Athletes following acute Concussion? Brain Inj. 2021 Jun 7;35(7):788-797. doi: 10.1080/02699052.2021.1911001.

Haidl TK, Hedderich DM, Rosen M, Kaiser N, Seves M, Lichtenstein T, Penzel N, Wenzel J, Kambeitz-Ilankovic L, Ruef A, Popovic D, Schultze-Lutter F, Chisholm K, Upthegrove R, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Ruhrmann S, Kambeitz J, Koutsouleris N. The non-specific nature of mental health and structural brain outcomes following childhood trauma. Psychol Med. 2021 Jul 6:1-10. doi: 10.1017/S0033291721002439.

Hazeldine J, Dinsdale RJ, Naumann DN, Acharjee A, Bishop JRB, Lord JM, Harrison P. Traumatic injury is associated with reduced deoxyribonuclease activity and dysregulation of the actin scavenging system. Burns Trauma. 2021 Apr 1;9:tkab001. doi: 10.1093/burnst/tkab001.

Hedayatpour N, Mohammed Sediq Rashid D, Izanloo Z, Seylaneh H, Falla D. Men and women show different adaptations of quadriceps activity following fatiguing contractions: An explanation for the increased incidence of sports-related knee injuries in women? J Electromyogr Kinesiol. 2021 Jun;58:102552. doi: 10.1016/j.jelekin.2021.102552.

Hill LJ, Botfield HF, Begum G, Qureshi O, Vigneswara V, Masood I, Barnes NM, Bruce L, Logan A. ILB® resolves inflammatory scarring and promotes functional tissue repair. NPJ Regen Med. 2021 Jan 7;6(1):3. doi: 10.1038/s41536-020-00110-2.

Kearney RS, Ji C, Warwick J, Parsons N, Brown J, Harrison P, Young J, Costa ML; ATM Trial Collaborators. Effect of Platelet-Rich Plasma Injection vs Sham Injection on Tendon Dysfunction in Patients With Chronic Midportion Achilles Tendinopathy: A Randomized Clinical Trial. JAMA. 2021 Jul 13;326(2):137-144. doi: 10.1001/jama.2021.6986.

Krynicki CR, Dazzan P, Pariante CM, Barnes NM, Vincent RC, Roberts A, Giordano A, Watson A, Suckling J, Barnes TRE, Husain N, Jones PB, Joyce E, Lawrie SM, Lewis S, Deakin B, Upthegrove R; BeneMin Study team. Deconstructing depression and negative symptoms of schizophrenia; differential and longitudinal immune correlates, and response to minocycline treatment. Brain Behav Immun. 2021 Jan;91:498-504. doi: 10.1016/j.bbi.2020.10.026.

Li LM, Dilley MD, Carson A, Twelftree J, Hutchinson PJ, Belli A, Betteridge S, Cooper PN, Griffin CM, Jenkins PO, Liu C, Sharp DJ, Sylvester R, Wilson MH, Turner MS, Greenwood R. Management of traumatic brain injury (TBI): a clinical neuroscience-led pathway for the NHS. Clin Med (Lond). 2021 Mar;21(2):e198-e205. doi: 10.7861/clinmed.2020-0336.

Malik NS, Chernbumroong S, Xu Y, Vassallo J, Lee J, Bowley DM, Hodgetts T, Moran CG, Lord JM, Belli A, Keene D, Foster M, Gkoutos GV. The BCD Triage Sieve outperforms all existing major incident triage tools: Comparative analysis using the UK national trauma registry population. EClinicalMedicine. 2021 May 15;36:100888. doi: 10.1016/j.eclinm.2021.100888.

Martin A, McAllister T, Merchant R, Nelson L, Ngwenya LB, Noel F, Nolan A, Palacios E, Perl D, Rabinowitz M, Rosand J, Sander A, Satris G, Schnyer D, Seabury S, Toga A, Valadka A, Vassar M, Zafonte R. Pathological Computed Tomography Features Associated With Adverse Outcomes After Mild Traumatic Brain Injury: A TRACK-TBI Study With External Validation in CENTER-TBI. JAMA Neurol. 2021 Jul 19:e212120. doi: 10.1001/jamaneurol.2021.2120.

Middlebrook N, Rushton AB, Abichandani D, Kuithan P, Heneghan NR, Falla D. Measures of central sensitization and their measurement properties in musculoskeletal trauma: A systematic review. Eur J Pain. 2021 Jan;25(1):71-87. doi: 10.1002/ejp.1670.

Middlebrook N, Heneghan NR, Falla D, Silvester L, Rushton AB, Soundy AA. Successful recovery following musculoskeletal trauma: protocol for a qualitative study of patients' and physiotherapists' perceptions. BMC Musculoskelet Disord. 2021 Feb 10;22(1):163. doi: 10.1186/s12891-021-04035-9.

Mikolić A, van Klaveren D, Groeniger JO, Wiegers EJA, Lingsma HF, Zeldovich M, von Steinbüchel N, Maas AIR, Roeters van Lennep JE, Polinder S; CENTER-TBI Participants and Investigators. Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury. J Neurotrauma. 2021 Jan 15;38(2):235-251. doi: 10.1089/neu.2020.7228.

Mikolić A, Polinder S, Steyerberg EW, Retel Helmrich IRA, Giacino JT, Maas AIR, van der Naalt J, Voormolen DC, von Steinbüchel N, Wilson L, Lingsma HF, van Klaveren D; Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study Participants and Investigators. Prediction of Global Functional Outcome and Post-Concussive Symptoms after Mild Traumatic Brain Injury: External Validation of Prognostic Models in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study. J Neurotrauma. 2021 Jan 15;38(2):196-209. doi: 10.1089/neu.2020.7074.

Nelson LD, Barber JK, Temkin NR, Dams-O'Connor K, Dikmen S, Giacino JT, Kramer MD, Levin HS, McCrea MA, Whyte J, Bodien YG, Yue JK, Manley GT; British Neurosurgical Trainee Research Collaborative (BNTRC). Validity of the Brief Test of Adult Cognition by Telephone in Level 1 Trauma Center Patients Six Months Post-Traumatic Brain Injury: A TRACK-TBI Study. J Neurotrauma. 2021 Apr 15;38(8):1048-1059. doi: 10.1089/neu.2020.7295.

O'Donnell A, Pauli R, Banellis L, Sokoliuk R, Hayton T, Sturman S, Veenith T, Yakoub KM, Belli A, Chennu S, Cruse D. The prognostic value of resting-state EEG in acute post-traumatic unresponsive states. Brain Commun. 2021 Mar 17;3(2):fcab017. doi: 10.1093/braincomms/fcab017.

Pedrero-Martin Y, Falla D, Martinez-Calderon J, Liew BXW, Scutari M, Luque-Suarez A. Self-efficacy beliefs mediate the association between pain intensity and pain interference in acute/subacute whiplash-associated disorders. Eur Spine J. 2021 Jun;30(6):1689-1698. doi: 10.1007/s00586-021-06731-5.

Pidgeon TE, Parthiban S, Malone P, Foster M, Chester DL. Injury patterns of patients with upper limb and hand trauma sustained during the COVID-19 pandemic lockdown in the UK: a retrospective cohort study. Hand Surg Rehabil. 2021 Jun;40(3):235-240. doi: 10.1016/j.hansur.2021.03.002.

Price J, Gardiner C, Harrison P. Platelet-enhanced plasma: Characterization of a novel candidate resuscitation fluid's extracellular vesicle content, clotting parameters, and thrombin generation capacity. Transfusion. 2021 Jul;61(7):2179-2194. doi: 10.1111/trf.16423.

Roberts I, Shakur-Still H, Aeron-Thomas A, Beaumont D, Belli A, Brenner A, Cargill M, Chaudhri R, Douglas N, Frimley L, Gilliam C, Geer A, Jamal Z, Jooma R, Mansukhani R, Miners A, Pott J, Prowse D, Shokunbi T, Williams J. Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT. Health Technol Assess. 2021 Apr;25(26):1-76. doi: 10.3310/hta25260.

Roberts A, Bentley L, Tang T, Stewart F, Pallini C, Juvvanapudi J, Wallace GR, Cooper AJ, Scott A, Thickett D, Lugg ST, Bancroft H, Hemming B, Ferris C, Langman G, Robinson A, Chapman J, Naidu B, Pinkney T, Taylor GS, Brock K, Stamataki Z, Brady CA, Curnow SJ, Gordon J, Qureshi O, Barnes NM. Ex vivo modelling of PD-1/PD-L1 immune checkpoint blockade under acute, chronic, and exhaustion-like conditions of T-cell stimulation. Sci Rep. 2021 Feb 17;11(1):4030. doi: 10.1038/s41598-021-83612-3.

Riemann L, Voormolen DC, Rauen K, Zweckberger K, Unterberg A, Younsi A; Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants. Persistent postconcussive symptoms in children and adolescents with mild traumatic brain injury receiving initial head computed tomography. J Neurosurg Pediatr. 2021 Feb 26:1-10. doi: 10.3171/2020.9.PEDS20421.

Sanderson A, Wang SF, Elgueta-Cancino E, Martinez-Valdes E, Sanchis-Sanchez E, Liew B, Falla D. The effect of experimental and clinical musculoskeletal pain on spinal and supraspinal projections to motoneurons and motor unit properties in humans: A systematic review. Eur J Pain. 2021 Sep;25(8):1668-1701. doi: 10.1002/ejp.1789.

Saliman NH, Belli A, Blanch R. Afferent visual manifestations of traumatic brain injury. J Neurotrauma. 2021 Jul 16. doi: 10.1089/neu.2021.0182.

Sewalt CA, Gravesteijn BY, Menon D, Lingsma HF, Maas AIR, Stocchetti N, Venema E, Lecky FE; CENTER TBI Participants and Investigators. Primary versus early secondary referral to a specialized neurotrauma center in patients with moderate/severe traumatic brain injury: a CENTER TBI study. Scand J Trauma Resusc Emerg Med. 2021 Aug 4;29(1):113. doi: 10.1186/s13049-021-00930-1.

Sokoliuk R, Degano G, Banellis L, Melloni L, Hayton T, Sturman S, Veenith T, Yakoub KM, Belli A, Noppeney U, Cruse D. Covert Speech Comprehension Predicts Recovery From Acute Unresponsive States. Ann Neurol. 2021 Apr;89(4):646-656. doi: 10.1002/ana.25995.

Thareja A, Hughes H, Alvarez-Lorenzo C, Hakkarainen JJ, Ahmed Z. Penetration Enhancers for Topical Drug Delivery to the Ocular Posterior Segment-A Systematic Review. Pharmaceutics. 2021 Feb 18;13(2):276. doi: 10.3390/pharmaceutics13020276.

Tollman J, Ahmed Z. Efficacy of tracheal tube introducers and stylets for endotracheal intubation in the prehospital setting: a systematic review and meta-analysis. Eur J Trauma Emerg Surg. 2021 Jul 31. doi: 10.1007/s00068-021-01762-5.

Toth E, Rassul SM, Berry M, Fulton D. A morphological analysis of activity-dependent myelination and myelin injury in transitional oligodendrocytes. Sci Rep. 2021 May 5;11(1):9588. doi: 10.1038/s41598-021-88887-0.

Turner GM, McMullan C, Aiyegbusi OL, Bem D, Marshall T, Calvert M, Mant J, Belli A. Stroke risk following traumatic brain injury: Systematic review and meta-analysis. Int J Stroke. 2021 Jun;16(4):370-384. doi: 10.1177/17474930211004277.

van Veen E, van der Jagt M, Citerio G, Stocchetti N, Gommers D, Burdorf A, Menon DK, Maas AIR, Kompanje EJO, Lingsma HF; CENTER-TBI investigators and participants. Occurrence and timing of withdrawal of life-sustaining measures in traumatic brain injury patients: a CENTER-TBI study. Intensive Care Med. 2021 Aug 5. doi: 10.1007/s00134-021-06484-1.

Wiegers EJA, Lingsma HF, Huijben JA, Cooper DJ, Citerio G, Frisvold S, Helbok R, Maas AIR, Menon DK, Moore EM, Stocchetti N, Dippel DW, Steyerberg EW, van der Jagt M; CENTER-TBI; OzENTER-TBI Collaboration Groups. Fluid balance and outcome in critically ill patients with traumatic brain injury (CENTER-TBI and OzENTER-TBI): a prospective, multicentre, comparative effectiveness study. Lancet Neurol. 2021 Aug;20(8):627-638. doi: 10.1016/S1474-4422(21)00162-9.

Yuh EL, Jain S, Sun X, Pisica D, Harris MH, Taylor SR, Markowitz AJ, Mukherjee P, Verheyden J, Giacino JT, Levin HS, McCrea M, Stein MB, Temkin NR, Diaz-Arrastia R, Robertson CS, Lingsma HF, Okonkwo DO, Maas AIR, Manley GT; TRACK-TBI Investigators for the CENTER-TBI Investigators, Adeoye O, Badjatia N, Boase K, Bodien Y, Corrigan JD, Crawford K, Dikmen S, Duhaime AC, Ellenbogen R, Feeser VR, Ferguson AR, Foreman B, Gardner R, Gaudette E, Gonzalez L, Gopinath S, Gullapalli R, Hemphill JC, Hotz G, Keene CD, Kramer J, Kreitzer N, Lindsell C, Machamer J, Madden C,

2020

Ahmed Z, Suggate EL, Logan A, Berry M. Retinal Ganglion Cell Survival and Axon Regeneration after Optic Nerve Transection is Driven by Cellular Intravitreal Sciatic Nerve Grafts. Cells. 2020 May 27;9(6):1335. doi: 10.3390/cells9061335.

Alalawi A, Luque-Suarez A, Fernandez-Sanchez M, Gallina A, Evans D, Falla D. Do measures of physical function enhance the prediction of persistent pain and disability following a whiplash injury? Protocol for a prospective observational study in Spain. BMJ Open. 2020 Oct 7;10(10):e035736. doi: 10.1136/bmjopen-2019-035736.

Al-Tarrah K, Jones SW, Moiemen N, Lord JM. Potential role of adipose tissue and its hormones in burns and critically III patients. Burns. 2020 Mar;46(2):259-266. doi: 10.1016/j.burns.2019.01.012.

Banbury C, Styles I, Eisenstein N, Zanier ER, Vegliante G, Belli A, Logan A, Goldberg Oppenheimer P. Spectroscopic detection of traumatic brain injury severity and biochemistry from the retina. Biomed Opt Express. 2020 Oct 8;11(11):6249-6261. doi: 10.1364/BOE.399473.

Beedham W, Belli A, Ingaralingam S, Haque S, Upthegrove R. The management of depression following traumatic brain injury: A systematic review with meta-analysis. Brain Inj. 2020 Aug 23;34(10):1287-1304. doi: 10.1080/02699052.2020.1797169.

Begum G, Reddy R, Yakoub KM, Belli A, Davies DJ, Di Pietro V. Differential Expression of Circulating Inflammatory Proteins Following Sport-Related Traumatic Brain Injury. Int J Mol Sci. 2020 Feb 12;21(4):1216. doi: 10.3390/ijms21041216.

Begum G, Leigh T, Courtie E, Moakes R, Butt G, Ahmed Z, Rauz S, Logan A, Blanch RJ. Rapid assessment of ocular drug delivery in a novel ex vivo corneal model. Sci Rep. 2020 Jul 16;10(1):11754. doi: 10.1038/s41598-020-68254-1.

Betz LT, Penzel N, Kambeitz-Ilankovic L, Rosen M, Chisholm K, Stainton A, Haidl TK, Wenzel J, Bertolino A, Borgwardt S, Brambilla P, Lencer R, Meisenzahl E, Ruhrmann S, Salokangas RKR, Schultze-Lutter F, Wood SJ, Upthegrove R, Koutsouleris N, Kambeitz J; PRONIA consortium. General psychopathology links burden of recent life events and psychotic symptoms in a network approach. NPJ Schizophr. 2020 Dec 15;6(1):40. doi: 10.1038/s41537-020-00129-w.

Blanch RJ, Kerber MT, Gensheimer WG. Deployed ophthalmic workload in support of US and NATO operations in Afghanistan. BMJ Mil Health. 2020 Mar 5:bmjmilitary-2019-001379. doi: 10.1136/bmjmilitary-2019-001379.

Breeze J, Blanch RJ, Mazzoli R, DuBose J, Bowley DM, Powers DB. Comparing the Management of Eye Injuries by Coalition Military Surgeons during the Iraq and Afghanistan Conflicts. Ophthalmology. 2020 Apr;127(4):458-466. doi: 10.1016/j.ophtha.2019.10.014.

Brenner A, Belli A, Chaudhri R, Coats T, Frimley L, Jamaluddin SF, Jooma R, Mansukhani R, Sandercock P, Shakur-Still H, Shokunbi T, Roberts I; CRASH-3 trial collaborators. Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial. Crit Care. 2020 Nov 11;24(1):560. doi: 10.1186/s13054-020-03243-4.

Chaudhary R, Scott RAH, Wallace G, Berry M, Logan A, Blanch RJ. Inflammatory and Fibrogenic Factors in Proliferative Vitreoretinopathy Development. Transl Vis Sci Technol. 2020 Feb 21;9(3):23. doi: 10.1167/tvst.9.3.23.

Chimen M, Evryviadou A, Box CL, Harrison MJ, Hazeldine J, Dib LH, Kuravi SJ, Payne H, Price JMJ, Kavanagh D, Iqbal AJ, Lax S, Kalia N, Brill A, Thomas SG, Belli A, Crombie N, Adams RA, Evans SA, Deckmyn H, Lord JM, Harrison P, Watson SP, Nash GB, Rainger GE. Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation. Haematologica. 2020 May;105(5):1248-1261. doi: 10.3324/haematol.2018.215145.

Courtie E, Veenith T, Logan A, Denniston AK, Blanch RJ. Retinal blood flow in critical illness and systemic disease: a review. Ann Intensive Care. 2020 Nov 12;10(1):152. doi: 10.1186/s13613-020-00768-3.

D'Asta F, Choong J, Thomas C, Adamson J, Wilson Y, Wilson D, Moiemen N, Farroha A. Paediatric burns epidemiology during COVID-19 pandemic and 'stay home' era. Burns. 2020 Sep;46(6):1471-1472. doi: 10.1016/j.burns.2020.06.028.

Dhillon A, Ahmad MSZ, Breeze J, Blanch RJ. Prolonged deployed hospital care in the management of military eye injuries. Eye (Lond). 2020 Nov;34(11):2106-2111. doi: 10.1038/s41433-020-1070-2.

Dinsdale RJ, Hazeldine J, Al Tarrah K, Hampson P, Devi A, Ermogenous C, Bamford AL, Bishop J, Watts S, Kirkman E, Dalle Lucca JJ, Midwinter M, Woolley T, Foster M, Lord JM, Moiemen N, Harrison P. Dysregulation of the actin scavenging system and inhibition of DNase activity following severe thermal injury. Br J Surg. 2020 Mar;107(4):391-401. doi: 10.1002/bjs.11310.

Di Pietro V, Yakoub KM, Caruso G, Lazzarino G, Signoretti S, Barbey AK, Tavazzi B, Lazzarino G, Belli A, Amorini AM. Antioxidant Therapies in Traumatic Brain Injury. Antioxidants (Basel). 2020 Mar 22;9(3):260. doi: 10.3390/antiox9030260.

Feng J, van Veen E, Yang C, Huijben JA, Lingsma HF, Gao G, Jiang J, Maas AIR; Collaborative European Neuro Trauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants. Comparison of Care System and Treatment Approaches for Patients with Traumatic Brain Injury in China versus Europe: A CENTER-TBI Survey Study. J Neurotrauma. 2020 Aug 15;37(16):1806-1817. doi: 10.1089/neu.2019.6900.

Forcione M, Yakoub KM, Chiarelli AM, Perpetuini D, Merla A, Sun R, Sawosz P, Belli A, Davies DJ. Dynamic contrast-enhanced near-infrared spectroscopy using indocyanine green on moderate and severe traumatic brain injury: a prospective observational study. Quant Imaging Med Surg. 2020 Nov;10(11):2085-2097. doi: 10.21037/qims-20-742.

Forcione M, Chiarelli AM, Davies DJ, Perpetuini D, Sawosz P, Merla A, Belli A. Cerebral perfusion and blood-brain barrier assessment in brain trauma using contrast-enhanced near-infrared spectroscopy with indocyanine green: A review. J Cereb Blood Flow Metab. 2020 Aug;40(8):1586-1598. doi: 10.1177/0271678X20921973.

Forcione M, Chiarelli AM, Perpetuini D, Davies DJ, O'Halloran P, Hacker D, Merla A, Belli A. Tomographic Task-Related Functional Near-Infrared Spectroscopy in Acute Sport-Related Concussion: An Observational Case Study. Int J Mol Sci. 2020 Aug 29;21(17):6273. doi: 10.3390/ijms21176273.

Foster MA, Taylor AE, Hill NE, Bentley C, Bishop J, Gilligan LC, Shaheen F, Bion JF, Fallowfield JL, Woods DR, Bancos I, Midwinter MM, Lord JM, Arlt W. Mapping the Steroid Response to Major Trauma From Injury to Recovery: A Prospective Cohort Study. J Clin Endocrinol Metab. 2020 Mar 1;105(3):925-37. doi: 10.1210/clinem/dgz302.

Gravesteijn BY, Sewalt CA, Nieboer D, Menon DK, Maas A, Lecky F, Klimek M, Lingsma HF; CENTER-TBI collaborators. Tracheal intubation in traumatic brain injury: a multicentre prospective observational study. Br J Anaesth. 2020 Oct;125(4):505-517. doi: 10.1016/j.bja.2020.05.067.

Gravesteijn BY, Nieboer D, Ercole A, Lingsma HF, Nelson D, van Calster B, Steyerberg EW; CENTER-TBI collaborators. Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury. J Clin Epidemiol. 2020 Jun;122:95-107. doi: 10.1016/j.jclinepi.2020.03.005.

Gravesteijn BY, Sewalt CA, Ercole A, Akerlund C, Nelson D, Maas AIR, Menon D, Lingsma HF, Steyerberg EW; Collaborative European NeuroTrauma Effectiveness Research for Traumatic Brain Injury Collaborators. Toward a New Multi-Dimensional Classification of Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research for Traumatic Brain Injury Study. J Neurotrauma. 2020 Apr 1;37(7):1002-1010. doi: 10.1089/neu.2019.6764.

Hacker DA, Jones CA, Michael T, Hawkins A, Clowes Z, Yasin E, Belli A, O'Neill N, Parnham J, Ustianowski M, Wardall H. Validation of the Neuropsychological Assessment Battery Screening Module (NAB-SM) in patients with traumatic brain injury. Appl Neuropsychol Adult. 2020 Dec 7:1-9. doi: 10.1080/23279095.2020.1852237.

Haidl TK, Schneider N, Dickmann K, Ruhrmann S, Kaiser N, Rosen M, Seves M, Lichtenstein T, Upthegrove R, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Rebekka L, Kambeitz J, Koutsouleris N, Schultze-Lutter F; PRONIA-consortium. Validation of the Bullying Scale for Adults - Results of the PRONIA-study. J Psychiatr Res. 2020 Oct;129:88-97. doi: 10.1016/j.jpsychires.2020.04.004.

Hawkridge K, Ahmed I, Ahmed Z. Evidence for the use of spinal collars in stabilising spinal injuries in the pre-hospital setting in trauma patients: a systematic review. Eur J Trauma Emerg Surg. 2020 Dec 21. doi: 10.1007/s00068-020-01576-x.

Huie JR, Mondello S, Lindsell CJ, Antiga L, Yuh EL, Zanier ER, Masson S, Rosario BL, Ferguson AR; Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Investigators, Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Participants and Investigators. Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations. J Neurotrauma. 2020 Apr 1. doi: 10.1089/neu.2019.6762.

Jacob L, Cogné M, Tenovuo O, Røe C, Andelic N, Majdan M, Ranta J, Ylen P, Dawes H, Azouvi P; CENTER-TBI Participants and Investigators. Predictors of Access to Rehabilitation in the Year Following Traumatic Brain Injury: A European Prospective and Multicenter Study. Neurorehabil Neural Repair. 2020 Sep;34(9):814-830. doi: 10.1177/1545968320946038.

Kitchen P, Salman MM, Halsey AM, Clarke-Bland C, MacDonald JA, Ishida H, Vogel HJ, Almutiri S, Logan A, Kreida S, Al-Jubair T, Winkel Missel J, Gourdon P, Törnroth-Horsefield S, Conner MT, Ahmed Z, Conner AC, Bill RM. Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema. Cell. 2020 May 14;181(4):784-799.e19. doi: 10.1016/j.cell.2020.03.037.

Lazzarino G, Amorini AM, Barnes NM, Bruce L, Mordente A, Lazzarino G, Pietro VD, Tavazzi B, Belli A, Logan A. Low Molecular Weight Dextran Sulfate (ILB) Administration Restores Brain Energy Metabolism Following Severe Traumatic Brain Injury in the Rat. Antioxidants (Basel). 2020 Sep 10;9(9):850. doi: 10.3390/antiox9090850.

Lee KC, Bamford A, Gardiner F, Agovino A, Ter Horst B, Bishop J, Grover L, Logan A, Moiemen N. Burns objective scar scale (BOSS): Validation of an objective measurement devices based burn scar scale panel. Burns. 2020 Feb;46(1):110-120. doi: 10.1016/j.burns.2019.05.008.

Luque-Suarez A, Falla D, Morales-Asencio JM, Martinez-Calderon J. Is kinesiophobia and pain catastrophising at baseline associated with chronic pain and disability in whiplash-associated disorders? A systematic review. Br J Sports Med. 2020 Aug;54(15):892-897. doi: 10.1136/bjsports-2018-099569.

Mahmood A, Needham K, Shakur-Still H, Harris T, Jamaluddin SF, Davies D, Belli A, Mohamed FL, Leech C, Lotfi HM, Moss P, Lecky F, Hopkins P, Wong D, Boyle A, Wilson M, Darwent M, Roberts I. Effect of tranexamic acid on intracranial haemorrhage and infarction in patients with traumatic brain injury: a pre-planned substudy in a sample of CRASH-3 trial patients. Emerg Med J. 2020 Dec 1;38(4):270-8. doi: 10.1136/emermed-2020-210424.

Malik NS, Munoz B, de Courcey C, Imran R, Lee KC, Chernbumroong S, Bishop J, Lord JM, Gkoutos G, Bowley DM, Foster MA. Violence-related knife injuries in a UK city; epidemiology and impact on secondary care resources. EClinicalMedicine. 2020 Mar 3;20:100296. doi: 10.1016/j.eclinm.2020.100296.

Manukjan N, Ahmed Z, Fulton D, Blankesteijn WM, Foulquier S. A Systematic Review of WNT Signaling in Endothelial Cell Oligodendrocyte Interactions: Potential Relevance to Cerebral Small Vessel Disease. Cells. 2020 Jun 25;9(6):1545. doi: 10.3390/cells9061545.

Mathers J, Moiemen N, Bamford A, Gardiner F, Tarver J. Ensuring that the outcome domains proposed for use in burns research are relevant to adult burn patients: a systematic review of qualitative research evidence. Burns Trauma. 2020 Nov 1;8:tkaa030. doi: 10.1093/burnst/tkaa030.

Mathieu F, Güting H, Gravesteijn B, Monteiro M, Glocker B, Kornaropoulos EN, Kamnistas K, Robertson CS, Levin H, Whitehouse DP, Das T, Lingsma HF, Maegele M, Newcombe VFJ, Menon DK; Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants. Impact of Antithrombotic Agents on Radiological Lesion Progression in Acute Traumatic Brain Injury: A CENTER-TBI Propensity-Matched Cohort Analysis. J Neurotrauma. 2020 Oct 1;37(19):2069-2080. doi: 10.1089/neu.2019.6911.

Mead B, Cullather E, Nakaya N, Niu Y, Kole C, Ahmed Z, Tomarev S. Viral delivery of multiple miRNAs promotes retinal ganglion cell survival and functional preservation after optic nerve crush injury. Exp Eye Res. 2020 Aug;197:108071. doi: 10.1016/j.exer.2020.108071.

McMullan C, Retzer A, Slade A, Kyte D, Jones L, Belli A, Calvert M, Turner GM. Care providers' and patients' attitudes toward using electronic-patient reported outcomes to support patients with traumatic brain injury: a qualitative study (PRiORiTy). Brain Inj. 2020 May 11;34(6):723-731. doi: 10.1080/02699052.2020.1740944.

Micieli JA, Bruce BB, Vasseneix C, Blanch RJ, Berezovsky DE, Newman NJ, Biousse V, Peragallo JH. Influence of Optic Nerve Appearance on Visual Outcome in Pediatric Idiopathic Intracranial Hypertension. Can J Neurol Sci. 2020 Sep;47(5):661-665. doi: 10.1017/cjn.2020.89.

Middlebrook N, Heneghan NR, Evans DW, Rushton A, Falla D. Reliability of temporal summation, thermal and pressure pain thresholds in a healthy cohort and musculoskeletal trauma population. PLoS One. 2020 May 29;15(5):e0233521. doi: 10.1371/journal.pone.0233521.

Mollan SP, Blanch RJ. Response to "Magnetic resonance or computed tomography venography in the evaluation of young overweight women with papilledema". Eye (Lond). 2020 Dec 15. doi: 10.1038/s41433-020-01358-0.

Nuccio S, Del Vecchio A, Casolo A, Labanca L, Rocchi JE, Felici F, Macaluso A, Mariani PP, Falla D, Farina D, Sbriccoli P. Muscle fiber conduction velocity in the vastus lateralis and medialis muscles of soccer players after ACL reconstruction. Scand J Med Sci Sports. 2020 Oct;30(10):1976-1984. doi: 10.1111/sms.13748.

Parish DC, Bidot S, Bruce BB, Micieli JA, Blanch RJ, Newman AB, Newman NJ, Biousse V. Self-Reported Weight and Height Among Idiopathic Intracranial Hypertension Patients. J Neuroophthalmol. 2020 Jun;40(2):157-162. doi: 10.1097/WNO.0000000000000861.

Popovic D, Ruef A, Dwyer DB, Antonucci LA, Eder J, Sanfelici R, Kambeitz-Ilankovic L, Oztuerk OF, Dong MS, Paul R, Paolini M, Hedderich D, Haidl T, Kambeitz J, Ruhrmann S, Chisholm K, Schultze-Lutter F, Falkai P, Pergola G, Blasi G, Bertolino A, Lencer R, Dannlowski U, Upthegrove R, Salokangas RKR, Pantelis C, Meisenzahl E, Wood SJ, Brambilla P, Borgwardt S, Koutsouleris N; PRONIA Consortium. Traces of Trauma: A Multivariate Pattern Analysis of Childhood Trauma, Brain Structure, and Clinical Phenotypes. Biol Psychiatry. 2020 Dec 1;88(11):829-842. doi: 10.1016/j.biopsych.2020.05.020.

Prete A, Taylor AE, Bancos I, Smith DJ, Foster MA, Kohler S, Fazal-Sanderson V, Komninos J, O'Neil DM, Vassiliadi DA, Mowatt CJ, Mihai R, Fallowfield JL, Annane D, Lord JM, Keevil BG, Wass JAH, Karavitaki N, Arlt W. Prevention of Adrenal Crisis: Cortisol Responses to Major Stress Compared to Stress Dose Hydrocortisone Delivery. J Clin Endocrinol Metab. 2020 Jul 1;105(7):2262-74. doi: 10.1210/clinem/dgaa133.

Rickard JJS, Di-Pietro V, Smith DJ, Davies DJ, Belli A, Oppenheimer PG. Rapid optofluidic detection of biomarkers for traumatic brain injury via surface-enhanced Raman spectroscopy. Nat Biomed Eng. 2020 Jun;4(6):610-623. doi: 10.1038/s41551-019-0510-4.

Robinson TE, Eisenstein NM, Cox SC, Moakes RJA, Thompson AM, Ahmed Z, Hughes EAB, Hill LJ, Stapley SA, Grover LM. Local injection of a hexametaphosphate formulation reduces heterotopic ossification in vivo. Mater Today Bio. 2020 Jun 2;7:100059. doi: 10.1016/j.mtbio.2020.100059.

Tegtmeier F, Schinzel R, Beer R, Bulters D, LeFrant JY, Sahuquillo J, Unterberg A, Andrews P, Belli A, Ibanez J, Lagares A, Mokry M, Willschke H, Flüh C, Schmutzhard E; NOSTRA Investigators. Efficacy of Ronopterin (VAS203) in Patients with Moderate and Severe Traumatic Brain Injury (NOSTRA phase III trial): study protocol of a confirmatory, placebo-controlled, randomised, double blind, multi-centre study. Trials. 2020 Jan 14;21(1):80. doi: 10.1186/s13063-019-3965-4.

Thomas CN, Courtie E, Bernardo-Colón A, Essex G, Rex TS, Ahmed Z, Blanch RJ. Assessment of necroptosis in the retina in a repeated primary ocular blast injury mouse model. Exp Eye Res. 2020 Aug;197:108102. doi: 10.1016/j.exer.2020.108102.

Timmers M, van Dijck JTJM, van Wijk RPJ, Legrand V, van Veen E, Maas AIR, Menon DK, Citerio G, Stocchetti N, Kompanje EJO; CENTER-TBI investigators and participants. How do 66 European institutional review boards approve one protocol for an international prospective observational study on traumatic brain injury? Experiences from the CENTER-TBI study. BMC Med Ethics. 2020 May 12;21(1):36. doi: 10.1186/s12910-020-00480-8.

Vande Vyvere T, De La Rosa E, Wilms G, Nieboer D, Steyerberg E, Maas AIR, Verheyden J, van den Hauwe L, Parizel PM; CENTER-TBI Participants and Investigators. Prognostic Validation of the NINDS Common Data Elements for the Radiologic Reporting of Acute Traumatic Brain Injuries: A CENTER-TBI Study. J Neurotrauma. 2020 Jun 1;37(11):1269-1282. doi: 10.1089/neu.2019.6710.

van Wijk RPJ, van Dijck JTJM, Timmers M, van Veen E, Citerio G, Lingsma HF, Maas AIR, Menon DK, Peul WC, Stocchetti N, Kompanje EJO; CENTER-TBI investigators and participants. Informed consent procedures in patients with an acute inability to provide informed consent: Policy and practice in the CENTER-TBI study. J Crit Care. 2020 Oct;59:6-15. doi: 10.1016/j.jcrc.2020.05.004.

Vigneswara V, Ahmed Z. The Role of Caspase-2 in Regulating Cell Fate. Cells. 2020 May 19;9(5):1259. doi: 10.3390/cells9051259.

Voormolen DC, Polinder S, von Steinbuechel N, Feng Y, Wilson L, Oppe M, Haagsma JA; CENTER-TBI participants and investigators. Health-related quality of life after traumatic brain injury: deriving value sets for the QOLIBRI-OS for Italy, The Netherlands and The United Kingdom. Qual Life Res. 2020 Nov;29(11):3095-3107. doi: 10.1007/s11136-020-02583-6.

Wilson L, Horton L, Kunzmann K, Sahakian BJ, Newcombe VF, Stamatakis EA, von Steinbuechel N, Cunitz K, Covic A, Maas A, Van Praag D, Menon D; CENTER-TBI participants and investigators. Understanding the relationship between cognitive performance and function in daily life after traumatic brain injury. J Neurol Neurosurg Psychiatry. 2020 Dec 2:jnnp-2020-324492. doi: 10.1136/jnnp-2020-324492.

Wu M, Downie LE, Grover LM, Moakes RJA, Rauz S, Logan A, Jiao H, Hill LJ, Chinnery HR. The neuroregenerative effects of topical decorin on the injured mouse cornea. J Neuroinflammation. 2020 May 4;17(1):142. doi: 10.1186/s12974-020-01812-6.

2019

Ahmed Z, Morgan-Warren PJ, Berry M, Scott RAH, Logan A. Effects of siRNA-Mediated Knockdown of GSK3β on Retinal Ganglion Cell Survival and Neurite/Axon Growth. Cells. 2019 Aug 22;8(9):956. doi: 10.3390/cells8090956.

Alalawi A, Gallina A, Sterling M, Falla D. Are physical factors associated with poor prognosis following a whiplash trauma?: a protocol for a systematic review and data synthesis. BMJ Open. 2019 Nov 19;9(11):e033298. doi: 10.1136/bmjopen-2019-033298.

Alsousou J, Keene DJ, Harrison P, Hulley P, Wagland S, Thompson JY, Parsons SR, Byrne C, Schlüssel MM, O’Connor HM, Dutton SJ, Lamb SE, Willett K. Platelet-rich plasma injection for adults with acute Achilles tendon rupture: the PATH-2 RCT. Southampton (UK): NIHR Journals Library; 2019 Nov.

Bage T, Edymann T, Metcalfe AD, Dheansa B, Mbundi L. Ex vivo culture of keratinocytes on papillary and reticular dermal layers remodels skin explants differently: towards improved wound care. Arch Dermatol Res. 2019 Oct;311(8):647-652. doi: 10.1007/s00403-019-01941-w.

Bentley C, Hazeldine J, Greig C, Lord J, Foster M. Dehydroepiandrosterone: a potential therapeutic agent in the treatment and rehabilitation of the traumatically injured patient. Burns Trauma. 2019 Aug 2;7:26. doi: 10.1186/s41038-019-0158-z. eCollection 2019.

Barry RJ, Sii F, Bruynseels A, Abbott J, Blanch RJ, MacEwen CJ, Shah P. The UK Paediatric Ocular Trauma Study 3 (POTS3): clinical features and initial management of injuries. Clin Ophthalmol. 2019 Jul 8;13:1165-1172. doi: 10.2147/OPTH.S201900.

Berry M, Ahmed Z, Logan A. Return of function after CNS axon regeneration: Lessons from injury-responsive intrinsically photosensitive and alpha retinal ganglion cells. Prog Retin Eye Res. 2019 Jul;71:57-67. doi: 10.1016/j.preteyeres.2018.11.006.

Blanch RJ, Bishop J, Javidi H, Murray PI. Effect of time to primary repair on final visual outcome after open globe injury. Br J Ophthalmol. 2019 doi: 10.1136/bjophthalmol-2017-311559.

Blanch RJ, Vasseneix C, Liczkowski A, Yiangou A, Aojula A, Micieli JA, Mollan SP, Newman NJ, Biousse V, Bruce BB, Sinclair A. Differing presenting features of idiopathic intracranial hypertension in the UK and US. Eye (Lond). 2019 Jun;33(6):1014-1019. doi: 10.1038/s41433-019-0359-5.

Blanch RJ, Horsburgh J, Creavin A; DOPS Study Group, Burdon MA, Williams C. Detection of Papilloedema Study (DOPS): rates of false positive papilloedema in the community. Eye (Lond). 2019 Jul;33(7):1073-1080. doi: 10.1038/s41433-019-0355-9.

Bown D, Belli A, Qureshi K, Davies D, Toman E, Upthegrove R. Post-traumatic stress disorder and self-reported outcomes after traumatic brain injury in victims of assault. PLoS One. 2019 Feb 7;14(2):e0211684. doi: 10.1371/journal.pone.0211684.

Bravo-Merodio L, Acharjee A, Hazeldine J, Bentley C, Foster M, Gkoutos GV, Lord JM. Machine learning for the detection of early immunological markers as predictors of multi-organ dysfunction. Sci Data. 2019 Dec 19;6(1):328. doi: 10.1038/s41597-019-0337-6.

Ceprian M, Fulton D. Glial Cell AMPA Receptors in Nervous System Health, Injury and Disease. Int J Mol Sci. 2019 May 17;20(10):2450. doi: 10.3390/ijms20102450.

Chouhan G, Moakes RJA, Esmaeili M, Hill LJ, deCogan F, Hardwicke J, Rauz S, Logan A, Grover LM. A self-healing hydrogel eye drop for the sustained delivery of decorin to prevent corneal scarring. Biomaterials. 2019 Jul;210:41-50. doi: 10.1016/j.biomaterials.2019.04.013.

Davies DJ, Clancy M, Dehghani H, Lucas SJE, Forcione M, Yakoub KM, Belli A. Cerebral Oxygenation in Traumatic Brain Injury: Can a Non-Invasive Frequency Domain Near-Infrared Spectroscopy Device Detect Changes in Brain Tissue Oxygen Tension as Well as the Established Invasive Monitor? J Neurotrauma. 2019 Apr 1;36(7):1175-1183. doi: 10.1089/neu.2018.5667.

Davies OG, Grover LM, Lewis MP, Liu Y. PDGF is a potent initiator of bone formation in a tissue engineered model of pathological ossification. J Tissue Eng Regen Med. 2018 Jan;12(1):e355-e367. doi: 10.1002/term.2320.

Farrukh F, Davies E, Berry M, Logan A, Ahmed Z. BMP4/Smad1 Signalling Promotes Spinal Dorsal Column Axon Regeneration and Functional Recovery After Injury. Mol Neurobiol. 2019 Oct;56(10):6807-6819. doi: 10.1007/s12035-019-1555-9.

Fernández-de-Las-Peñas C, Falla D, Palacios-Ceña M, De-la-Llave-Rincón AI, Schneebeli A, Barbero M. Perceived Pain Extent Is Not Associated with Physical, Psychological, or Psychophysical Outcomes in Women with Carpal Tunnel Syndrome. Pain Med. 2019 Jun 1;20(6):1185-1192. doi: 10.1093/pm/pny248.

Hazeldine J, Dinsdale RJ, Harrison P, Lord JM. Traumatic Injury and Exposure to Mitochondrial-Derived Damage Associated Molecular Patterns Suppresses Neutrophil Extracellular Trap Formation. Front Immunol. 2019 Apr 2;10:685. doi: 10.3389/fimmu.2019.00685.

Keene DJ, Alsousou J, Harrison P, Hulley P, Wagland S, Parsons SR, Thompson JY, O'Connor HM, Schlüssel MM, Dutton SJ, Lamb SE, Willett K; PATH-2 trial group. Platelet rich plasma injection for acute Achilles tendon rupture: PATH-2 randomised, placebo controlled, superiority trial. BMJ. 2019 Nov 20;367:l6132. doi: 10.1136/bmj.l6132.

Lazzarino G, Amorini AM, Signoretti S, Musumeci G, Lazzarino G, Caruso G, Pastore FS, Di Pietro V, Tavazzi B, Belli A. Pyruvate Dehydrogenase and Tricarboxylic Acid Cycle Enzymes Are Sensitive Targets of Traumatic Brain Injury Induced Metabolic Derangement. Int J Mol Sci. 2019 Nov 16;20(22):5774. doi: 10.3390/ijms20225774.

Liew BXW, Scutari M, Peolsson A, Peterson G, Ludvigsson ML, Falla D. Investigating the Causal Mechanisms of Symptom Recovery in Chronic Whiplash-associated Disorders Using Bayesian Networks. Clin J Pain. 2019 Aug;35(8):647-655. doi: 10.1097/AJP.0000000000000728.

Liu X, Kale AU, Capewell N, Talbot N, Ahmed S, Keane PA, Mollan S, Belli A, Blanch RJ, Veenith T, Denniston AK. Optical coherence tomography (OCT) in unconscious and systemically unwell patients using a mobile OCT device: a pilot study. BMJ Open. 2019 Nov 7;9(11):e030882. doi: 10.1136/bmjopen-2019-030882.

Mee H, Kolias AG, Chari A, Ercole A, Lecky F, Turner C, Tudur-Smith C, Coles J, Anwar F, Belli A, Manford M, Ham T, McMahon C, Bulters D, Uff C, Duncan JS, Wilson MH, Marson AG, Hutchinson PJ. Pharmacological management of post-traumatic seizures in adults: current practice patterns in the UK and the Republic of Ireland. Acta Neurochir (Wien). 2019 Mar;161(3):457-464. doi: 10.1007/s00701-018-3683-9.

Middlebrook N, Rushton AB, Heneghan NR, Falla D. Measures of central sensitisation and their measurement properties in the adult musculoskeletal trauma population: a protocol for a systematic review and data synthesis. BMJ Open. 2019 Mar 23;9(3):e023204. doi: 10.1136/bmjopen-2018-023204.

Naumann DN, Hazeldine J, Bishop J, Midwinter MJ, Harrison P, Nash G, Hutchings SD. Impact of plasma viscosity on microcirculatory flow after traumatic haemorrhagic shock: A prospective observational study. Clin Hemorheol Microcirc. 2019;71(1):71-82. doi: 10.3233/CH-180397.

Qureshi KL, Upthegrove R, Toman E, Sawlani V, Davies DJ, Belli A. Post-traumatic stress disorder in UK civilians with traumatic brain injury: an observational study of TBI clinic attendees to estimate PTSD prevalence and its relationship with radiological markers of brain injury severity. BMJ Open. 2019 Feb 19;9(2):e021675. doi: 10.1136/bmjopen-2018-021675.

Retzer A, Turner GM, Slade A, Kyte D, McMullan C, Jones L, Belli A, Calvert M. Electronic patient reported outcomes to support care of patients with traumatic brain injury: PRiORiTy study qualitative protocol. BMJ Open. 2019 Jan 25;9(1):e024617. doi: 10.1136/bmjopen-2018-024617.

Ris I, Barbero M, Falla D, Larsen MH, Kraft MN, Søgaard K, Juul-Kristensen B. Pain extent is more strongly associated with disability, psychological factors, and neck muscle function in people with non-traumatic versus traumatic chronic neck pain: a cross sectional study. Eur J Phys Rehabil Med. 2019 Feb;55(1):71-78. doi: 10.23736/S1973-9087.18.04977-8.

Sharma R, Shultz SR, Robinson MJ, Belli A, Hibbs ML, O'Brien TJ, Semple BD. Infections after a traumatic brain injury: The complex interplay between the immune and neurological systems. Brain Behav Immun. 2019 Jul;79:63-74. doi: 10.1016/j.bbi.2019.04.034.

Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O'Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, Folkerth RD, Gentleman S, Giza CC, Grady MS, Helmy A, Herceg M, Holton JL, Howell D, Hutchinson PJ, Iacono D, Iglesias JE, Ikonomovic MD, Johnson VE, Keene CD, Kofler JK, Koliatsos VE, Lee EB, Levin H, Lifshitz J, Ling H, Loane DJ, Love S, Maas AI, Marklund N, Master CL, McElvenny DM, Meaney DF, Menon DK, Montine TJ, Mouzon B, Mufson EJ, Ojo JO, Prins M, Revesz T, Ritchie CW, Smith C, Sylvester R, Tang CY, Trojanowski JQ, Urankar K, Vink R, Wellington C, Wilde EA, Wilson L, Yeates K, Smith DH. Primum non nocere: a call for balance when reporting on CTE. Lancet Neurol. 2019 Mar;18(3):231-233. doi: 10.1016/S1474-4422(19)30020-1.

Stevens AR, Su Z, Toman E, Belli A, Davies D. Optical pupillometry in traumatic brain injury: neurological pupil index and its relationship with intracranial pressure through significant event analysis. Brain Inj. 2019;33(8):1032-1038. doi: 10.1080/02699052.2019.1605621.

Stevens AR, Ahmed U, Vigneswara V, Ahmed Z. Pigment Epithelium-Derived Factor Promotes Axon Regeneration and Functional Recovery After Spinal Cord Injury. Mol Neurobiol. 2019 Nov;56(11):7490-7507. doi: 10.1007/s12035-019-1614-2.

Steyerberg EW, Wiegers E, Sewalt C, Buki A, Citerio G, De Keyser V, Ercole A, Kunzmann K, Lanyon L, Lecky F, Lingsma H, Manley G, Nelson D, Peul W, Stocchetti N, von Steinbüchel N, Vande Vyvere T, Verheyden J, Wilson L, Maas AIR, Menon DK; CENTER-TBI Participants and Investigators. Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study. Lancet Neurol. 2019 Oct;18(10):923-934. doi: 10.1016/S1474-4422(19)30232-7.

Thomas CN, Thompson AM, Ahmed Z, Blanch RJ. Retinal Ganglion Cells Die by Necroptotic Mechanisms in a Site-Specific Manner in a Rat Blunt Ocular Injury Model. Cells. 2019 Nov 26;8(12):1517. doi: 10.3390/cells8121517.

Thompson A, Berry M, Logan A, Ahmed Z. Activation of the BMP4/Smad1 Pathway Promotes Retinal Ganglion Cell Survival and Axon Regeneration. Invest Ophthalmol Vis Sci. 2019 Apr 1;60(5):1748-1759. doi: 10.1167/iovs.18-26449.

Turner GM, Slade A, Retzer A, McMullan C, Kyte D, Belli A, Calvert M. An introduction to patient-reported outcome measures (PROMs) in trauma. J Trauma Acute Care Surg. 2019 Feb;86(2):314-320. doi: 10.1097/TA.0000000000002102.

Tuxworth RI, Taylor MJ, Martin Anduaga A, Hussien-Ali A, Chatzimatthaiou S, Longland J, Thompson AM, Almutiri S, Alifragis P, Kyriacou CP, Kysela B, Ahmed Z. Attenuating the DNA damage response to double-strand breaks restores function in models of CNS neurodegeneration. Brain Commun. 2019 Jul 2;1(1):fcz005. doi: 10.1093/braincomms/fcz005.

Vande Vyvere T, Wilms G, Claes L, Martin Leon F, Nieboer D, Verheyden J, van den Hauwe L, Pullens P, Maas AIR, Parizel PM; Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Investigators and Participants. Central versus Local Radiological Reading of Acute Computed Tomography Characteristics in Multi-Center Traumatic Brain Injury Research. J Neurotrauma. 2019 Apr 1;36(7):1080-1092. doi: 10.1089/neu.2018.6061.

Vigneswara V, Ahmed Z. Pigment epithelium-derived factor mediates retinal ganglion cell neuroprotection by suppression of caspase-2. Cell Death Dis. 2019 Feb 4;10(2):102. doi: 10.1038/s41419-019-1379-6.

Yakoub KM, Davies DJ, Su Z, Bentley C, Forcione M, Toman E, Hammond D, Watson CN, Bishop J, Cooper L, Barbey AK, Sawlani V, Di Pietro V, Grey MJ, Belli A. Investigation into repetitive concussion in sport (RECOS): study protocol of a prospective, exploratory, observational cohort study. BMJ Open. 2019 Jul 4;9(7):e029883. doi: 10.1136/bmjopen-2019-029883.

2018

Afshari FT, Yakoub KM, Zisakis A, Thomas A, Ughratdar I, Sturman S, Belli A. Traumatic dural venous sinus thrombosis; a challenge in management of head injury patients. J Clin Neurosci. 2018 Nov;57:169-173. doi: 10.1016/j.jocn.2018.08.047.

Almutiri S, Berry M, Logan A, Ahmed Z. Non-viral-mediated suppression of AMIGO3 promotes disinhibited NT3-mediated regeneration of spinal cord dorsal column axons. Sci Rep. 2018 Jul 16;8(1):10707. doi: 10.1038/s41598-018-29124-z.

Al-Tarrah K, Hewison M, Moiemen N, Lord JM. Vitamin D status and its influence on outcomes following major burn injury and critical illness. Burns Trauma. 2018 Apr 16;6:11. doi: 10.1186/s41038-018-0113-4.

Alves DR, Booth SP, Scavone P, Schellenberger P, Salvage J, Dedi C, Thet N, Jenkins ATA, Waters R, Ng KW, Overall ADJ, Nzakizwanayo J, Metcalfe AD and Jones BV (2018). Development of a high-throughput ex-vivo burn wound model using porcine skin, and its application to evaluate new approaches to control wound infection. Front. Cell. Infect. Microbiol. doi: 10.3389/fcimb.2018.00196

Andrews N, Jones LL, Moiemen N, Calvert M, Kinghorn P, Litchfield I, Bishop J, Deeks JJ, Mathers J; PEGASUS Study Group. Below the surface: Parents' views on the factors that influence treatment adherence in paediatric burn scar management - A qualitative study. Burns. 2018 May;44(3):626-635. doi: 10.1016/j.burns.2017.09.003.

Badawy AR, Hassan MU, Elsherif M, Ahmed Z, Yetisen AK, Butt H. Contact Lenses for Color Blindness. Adv Healthc Mater. 2018 Jun;7(12):e1800152. doi: 10.1002/adhm.201800152.

Bakr A, Belli A. A systematic review of levetiracetam versus phenytoin in the prevention of late post-traumatic seizures and survey of UK neurosurgical prescribing practice of antiepileptic medication in acute traumatic brain injury. Br J Neurosurg. 2018 Jun;32(3):237-244. doi: 10.1080/02688697.2018.1464118.

Begum G, O'Neill J, Chaudhary R, Blachford K, Snead DRJ, Berry M, Scott RAH, Logan A, Blanch RJ. Altered Decorin Biology in Proliferative Vitreoretinopathy: A Mechanistic and Cohort Study. Invest Ophthalmol Vis Sci 2018 59(12):4929-4936.

Begum G, Otsu M, Ahmed U, Ahmed Z, Stevens A, Fulton D. NF-Y-dependent regulation of glutamate receptor 4 expression and cell survival in cells of the oligodendrocyte lineage. Glia. 2018 Sep;66(9):1896-1914. doi: 10.1002/glia.23446.

Berry M, Ahmed Z, Logan A. Return of function after CNS axon regeneration: Lessons from injury-responsive intrinsically photosensitive and alpha retinal ganglion cells. Prog Retin Eye Res. 2018 Nov 17. pii: S1350-9462(18)30047-8. doi: 10.1016/j.preteyeres.2018.11.006. Review.

Blanch RJ, Micieli JA, Oyesiku NM, Newman NJ, Biousse V. Optical coherence tomography retinal ganglion cell complex analysis for the detection of early chiasmal compression. Pituitary. 2018 Oct;21(5):515-523. doi: 10.1007/s11102-018-0906-2.

Cato LD, Wearn CM, Bishop JRB, Stone MJ, Harrison P, Moiemen N. Platelet count: A predictor of sepsis and mortality in severe burns. Burns. 2018 Mar;44(2):288-297. doi: 10.1016/j.burns.2017.08.015.

Di Pietro V, Yakoub KM, Scarpa U, Di Pietro C, Belli A. MicroRNA Signature of Traumatic Brain Injury: From the Biomarker Discovery to the Point-of-Care. Front Neurol. 2018 Jun 14;9:429. doi: 10.3389/fneur.2018.00429.

Di Pietro V, Porto E, Ragusa M, Barbagallo C, Davies D, Forcione M, Logan A, Di Pietro C, Purrello M, Grey M, Hammond D, Sawlani V, Barbey AK, Belli A. Salivary MicroRNAs: Diagnostic Markers of Mild Traumatic Brain Injury in Contact-Sport. Front Mol Neurosci. 2018 Aug 20;11:290. doi: 10.3389/fnmol.2018.00290.

Halsey AM, Conner AC, Bill RM, Logan A, Ahmed Z. Aquaporins and their regulation after spinal cord injury. Cells. 2018 Oct 18;7(10). pii: E174. doi: 10.3390/cells7100174. Review.

Halstead FD, Lee KC, Kwei J, Dretzke J, Oppenheim BA, Moiemen NS. A systematic review of quantitative burn wound microbiology in the management of burns patients. Burns. 2018 Feb;44(1):39-56. doi: 10.1016/j.burns.2017.06.008.

Harrison P; Subcommittee on Platelet Physiology (2018) The use of platelets in regenerative medicine and proposal for a new classification system: guidance from the SSC of the ISTH. J Thromb Haemost. 16(9):1895-1900. doi: 10.1111/jth.14223

Heneghan NR, Smith R, Tyros I, Falla D, Rushton A. Thoracic dysfunction in whiplash associated disorders: A systematic review. PLoS One. 2018 Mar 23;13(3):e0194235. doi: 10.1371/journal.pone.0194235.

Hill LJ, Moakes RJA, Vareechon C, Butt G, Ng A, Brock K, Chouhan G, Vincent RC, Abbondante S, Williams RL, Barnes NM, Pearlman E, Wallace GR, Rauz S, Logan A, Grover LM. Sustained release of decorin to the surface of the eye enables scarless corneal regeneration. NPJ Regen Med. 2018 Dec 21;3:23. doi: 10.1038/s41536-018-0061-4. eCollection 2018.

Hill LJ, Mead B, Thomas CN, Foale S, Feinstein E, Berry M, Blanch RJ, Ahmed Z, Logan A. TGF-β-induced IOP elevations are mediated by RhoA in the early but not the late fibrotic phase of open angle glaucoma. Mol Vis. 2018 Oct 29;24:712-726.

Huijben JA, Volovici V, Cnossen MC, Haitsma IK, Stocchetti N, Maas AIR, Menon DK, Ercole A, Citerio G, Nelson D, Polinder S, Steyerberg EW, Lingsma HF, van der Jagt M; CENTER-TBI investigators and participants. Variation in general supportive and preventive intensive care management of traumatic brain injury: a survey in 66 neurotrauma centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study. Crit Care. 2018 Apr 13;22(1):90. doi: 10.1186/s13054-018-2000-6.

Huijben JA, van der Jagt M, Cnossen MC, Kruip MJHA, Haitsma IK, Stocchetti N, Maas AIR, Menon DK, Ercole A, Maegele M, Stanworth SJ, Citerio G, Polinder S, Steyerberg EW, Lingsma HF; CENTER-TBI Investigators and Participants. Variation in Blood Transfusion and Coagulation Management in Traumatic Brain Injury at the Intensive Care Unit: A Survey in 66 Neurotrauma Centers Participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Study. J Neurotrauma. 2018 Jan 15;35(2):323-332. doi: 10.1089/neu.2017.5194.

Kuravi SJ, Harrison P, Rainger GE, Nash GB (2018) Ability of Platelet-Derived Extracellular Vesicles to Promote Neutrophil-Endothelial Cell Interactions. Inflammation. doi: 10.1007/s10753-018-0893-5 [Epub ahead of print].

Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Promote Neuroprotection in a Genetic DBA/2J Mouse Model of Glaucoma. Mead B, Ahmed Z, Tomarev S. Invest Ophthalmol Vis Sci. 2018 Nov 1;59(13):5473-5480. doi: 10.1167/iovs.18-25310.

Moiemen N, Mathers J, Jones L, Bishop J, Kinghorn P, Monahan M, Calvert M, Slinn G, Gardiner F, Bamford A, Wright S, Litchfield I, Andrews N, Turner K, Grant M, Deeks J. Pressure garment to prevent abnormal scarring after burn injury in adults and children: the PEGASUS feasibility RCT and mixed-methods study. Health Technol Assess. 2018 Jun;22(36):1-162. doi: 10.3310/hta22360.

Montague SJ, Delierneux C, Lecut C, Layios N, Dinsdale RJ, Lee CS, Poulter NS, Andrews RK, Hampson P, Wearn CM, Maes N, Bishop J, Bamford A, Gardiner C, Lee WM, Iqbal T, Moiemen N, Watson SP, Oury C, Harrison P, Gardiner EE. Soluble GPVI is elevated in injured patients: shedding is mediated by fibrin activation of GPVI. Blood Adv. 2018 Feb 13;2(3):240-251. doi: 10.1182/bloodadvances.2017011171.

Naumann D., Hazeldine J., Bishop J., Midwinter M., Harrison P., Nash G., Hutchings S. (2018) Impact of plasma viscosity on microcirculatory flow dynamics after traumatic haemorrhagic shock: a prospective observational study. Clin Hemorheol Microcirc. doi: 10.3233/CH-180397.

Naumann DN, Hazeldine J, Midwinter MJ, Hutchings SD, Harrison P. Poor microcirculatory flow dynamics are associated with endothelial cell damage and glycocalyx shedding after traumatic hemorrhagic shock. J Trauma Acute Care Surg. 2018 Jan;84(1):81-88. doi: 10.1097/TA.0000000000001695.

Naumann DN, Hazeldine J, Davies DJ, Bishop J, Midwinter MJ, Belli A, Harrison P, Lord JM. Endotheliopathy of Trauma is an on-Scene Phenomenon, and is Associated with Multiple Organ Dysfunction Syndrome: A Prospective Observational Study. Shock. 2018 Apr;49(4):420-428. doi: 10.1097/SHK.0000000000000999.

Roberts I, Belli A, Brenner A, Chaudhri R, Fawole B, Harris T, Jooma R, Mahmood A, Shokunbi T, Shakur H; CRASH-3 trial collaborators. Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial. Wellcome Open Res. 2018 Sep 26;3:86. doi: 10.12688/wellcomeopenres.14700.2.

Rowland, T., Perry, B., Upthegrove, R., Barnes, N.M., Chatterjee, J., Marwaha, S. Neurotrophins, cytokines and oxidative stress mediators, and mood state in bipolar disorder: systematic review and meta-analyses. Br J Psychiatry 213, 514-525, 2018.

Rushton AB, Evans DW, Middlebrook N, Heneghan NR, Small C, Lord J, Patel JM, Falla D. Development of a screening tool to predict the risk of chronic pain and disability following musculoskeletal trauma: protocol for a prospective observational study in the United Kingdom. BMJ Open. 2018 Apr 28;8(4):e017876. doi: 10.1136/bmjopen-2017-017876.

Rushton AB, Verra ML, Emms A, Heneghan NR, Falla D, Reddington M, Cole AA, Willems P, Benneker L, Selvey D, Hutton M, Heymans MW, Staal JB. Development and validation of two clinical prediction models to inform clinical decision-making for lumbar spinal fusion surgery for degenerative disorders and rehabilitation following surgery: protocol for a prospective observational study. BMJ Open. 2018 May 22;8(5):e021078. doi: 10.1136/bmjopen-2017-021078.

Samantha J. Montague, Céline Delierneux, Christelle Lecut, Nathalie Layios,Robert J. Dinsdale, Natalie S. Poulter, Robert K. Andrews, Peter Hampson, Christopher M. Wearn, Christine Lee, Nathalie Maes, Jonathan Bishop, Amy Bamford, Chris Gardiner, Tariq Iqbal, Naiem Moiemen, Steve P. Watson, Cécile Oury, Elizabeth E. Gardiner, Paul Harrison (2018) Fibrin induces GPVI shedding from platelets: soluble GPVI is elevated in patients with thermal injury. Blood Advances, 2(3):240-251.

Sii F, Barry RJ, Abbott J, Blanch RJ, MacEwen CJ, Shah P. The UK Paediatric Ocular Trauma Study 2 (POTS2): demographics and mechanisms of injuries. Clin Ophthalmol. 2018 Jan 9;12:105-111.

Sullivan J, Mirbahai L, Lord JM. Major trauma and acceleration of the ageing process. Ageing Res Rev. 2018 Dec;48:32-39. doi: 10.1016/j.arr.2018.10.001.

Ter Horst B, Chouhan G, Moiemen NS, Grover LM. Advances in keratinocyte delivery in burn wound care. Adv Drug Deliv Rev. 2018 Jan 1;123:18-32. doi: 10.1016/j.addr.2017.06.012.

Thomas CN, Thompson AM, McCance E, Berry M, Logan A, Blanch RJ, Ahmed Z. Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury. Invest Ophthalmol Vis Sci. 2018 Sep 4;59(11):4453-4462. doi: 10.1167/iovs.18-24045.

Thomas CN, Thompson AN, McCance E, Berry M, Logan A, Blanch RJ, Ahmed Z. Caspase-2 mediates site-specific retinal ganglion cell death after blunt ocular injury. Invest Ophthalmol Vis Sci 2018 59(11): 4453-4462.

van Veen E, van der Jagt M, Cnossen MC, Maas AIR, de Beaufort ID, Menon DK, Citerio G, Stocchetti N, Rietdijk WJR, van Dijck JTJM, Kompanje EJO; CENTER-TBI investigators and participants. Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study. Crit Care. 2018 Nov 16;22(1):306. doi: 10.1186/s13054-018-2241-4.

Wearn C, Lee KC, Hardwicke J, Allouni A, Bamford A, Nightingale P, Moiemen N. Prospective comparative evaluation study of Laser Doppler Imaging and thermal imaging in the assessment of burn depth. Burns. 2018 Feb;44(1):124-133. doi: 10.1016/j.burns.2017.08.004.

Yakoub KM, O'Halloran P, Davies DJ, Bentley C, Watson CN, Forcione M, Scarpa U, Bishop JRB, Toman E, Hammond D, Cross MJ, Stokes KA, Kemp SPT, Menon DK, Di Pietro V, Belli A. Study of Concussion in Rugby Union through MicroRNAs (SCRUM): a study protocol of a prospective, observational cohort study. BMJ Open. 2018 Nov 25;8(11):e024245. doi: 10.1136/bmjopen-2018-024245.

2017

Ahmed, R., Newman, A.S., O’Daly, J., Duffy, S., Grafton, G., Brady, C.A., Curnow, J., Barnes, N.M., Gordon, J. Inosine Acedoben Dimepranol promotes an early and sustained increase in the natural killer cell component of circulating lymphocytes: A clinical trial supporting anti-viral indications. Int Immunopharmacology 42, 108-114, 2017.

Alsousou J, Keene DJ, Hulley PA, Harrison P, Wagland S, Byrne C, Schlüssel MM, Dutton SJ, Lamb SE, Willett K. Platelet rich Plasma in Achilles Tendon Healing 2 (PATH-2) trial: protocol for a multicentre, participant and assessor-blinded, parallel-group randomised clinical trial comparing platelet-rich plasma (PRP) injection versus placebo injection for Achilles tendon rupture. BMJ Open. 2017 Nov 16;7(11):e018135. doi: 10.1136/bmjopen-2017-018135.

Al-Tarrah K, Moiemen N, Lord JM. The influence of sex steroid hormones on the response to trauma and burn injury. Burns Trauma. 2017 Sep 14;5:29. doi: 10.1186/s41038-017-0093-9.

Amorini AM, Lazzarino G, Di Pietro V, Signoretti S, Lazzarino G, Belli A, Tavazzi B. Severity of experimental traumatic brain injury modulates changes in concentrations of cerebral free amino acids. J Cell Mol Med. 2017 Mar;21(3):530-542. doi: 10.1111/jcmm.12998.

Blanch RJ, Bishop J, Javidi H, Murray PI. Effect of time to primary repair on final visual outcome after open globe injury. Br J Ophthalmol. 2019 doi: 10.1136/bjophthalmol-2017-311559. [Epub ahead of print]

Bluebelle Study Group, Reeves BC, Andronis L, Blazeby JM, Blencowe NS, Calvert M, Coast J, Draycott T, Donovan JL, Gooberman-Hill R, Longman RJ, Magill L, Mathers JM, Pinkney TD, Rogers CA, Rooshenas L, Torrance A, Welton NJ, Woodward M, Ashton K, Bera KD, Clayton GL, Culliford LA, Dumville JC, Elliott D, Ellis L, Gould-Brown H, Macefield RC, McMullan C, Pope C, Siassakos D, Strong S, Talbot H. A mixed-methods feasibility and external pilot study to inform a large pragmatic randomised controlled trial of the effects of surgical wound dressing strategies on surgical site infections (Bluebelle Phase B): study protocol for a randomised controlled trial. Trials. 2017 Aug 29;18(1):401. doi: 10.1186/s13063-017-2102-5.

Caspases in retinal ganglion cell death and axon regeneration. Thomas CN, Berry M, Logan A, Blanch RJ, Ahmed Z. Cell Death Discov. 2017 Jul 3;3:17032. doi: 10.1038/cddiscovery.2017.32.

Cato LD, Wearn CM, Bishop JRB, Stone MJ, Harrison P, Moiemen N. (2017)Platelet count: A predictor of sepsis and mortality in severe burns. Burns. 2017 Oct 9. pii: S0305-4179(17)30468-0.

Cnossen MC, Huijben JA, van der Jagt M, Volovici V, van Essen T, Polinder S, Nelson D, Ercole A, Stocchetti N, Citerio G, Peul WC, Maas AIR, Menon D, Steyerberg EW, Lingsma HF; CENTER-TBI investigators. Variation in monitoring and treatment policies for intracranial hypertension in traumatic brain injury: a survey in 66 neurotrauma centers participating in the CENTER-TBI study. Crit Care. 2017 Sep 6;21(1):233. doi: 10.1186/s13054-017-1816-9.

de Cogan F, Hill LJ, Lynch A, Morgan-Warren PJ, Lechner J, Berwick MR, Peacock AFA, Chen M, Scott RAH, Xu H, Logan A. Topical Delivery of Anti-VEGF Drugs to the Ocular Posterior Segment Using Cell-Penetrating Peptides. Invest Ophthalmol Vis Sci. 2017 May 1;58(5):2578-2590. doi: 10.1167/iovs.16-20072.

D’Asta F, Webber M, Bishop J, Halstead F, Moiemen N, Lord J, Harrison P (2017) The Contribution of Leucocytes to the Antimicrobial Activity of Platelet Rich Plasma Preparations: a systematic review, Platelets, Jul 6:1-12. doi: 10.1080/09537104.2017.1317731

Dinsdale RJ, Devi A, Hampson P, Wearn CM, Bamford AL, Hazeldine J, Bishop J, Ahmed S, Watson C, Lord JM, Moiemen N, Harrison P. (2017) Changes in novel haematological parameters following thermal injury, A prospective observational cohort study, Scientific Reports, 12;7(1):3211. doi: 10.1038/s41598-017-03222-w.

Di Pietro V, Ragusa M, Davies D, Su Z, Hazeldine J, Lazzarino G, Hill LJ, Crombie N, Foster M, Purrello M, Logan A, Belli A. MicroRNAs as Novel Biomarkers for the Diagnosis and Prognosis of Mild and Severe Traumatic Brain Injury. J Neurotrauma. 2017 Jun 1;34(11):1948-1956. doi: 10.1089/neu.2016.4857.

Di Pietro V, Lazzarino G, Amorini AM, Signoretti S, Hill LJ, Porto E, Tavazzi B, Lazzarino G, Belli A. Fusion or Fission: The Destiny of Mitochondria In Traumatic Brain Injury of Different Severities. Sci Rep. 2017 Aug 23;7(1):9189. doi: 10.1038/s41598-017-09587-2.

Foale S, Berry M, Logan A, Fulton D, Ahmed Z. LINGO-1 and AMIGO3, potential therapeutic targets for neurological and dysmyelinating disorders? Neural Regen Res. 2017 Aug;12(8):1247-1251. doi: 10.4103/1673-5374.213538.

Hacker D, Jones CA, Clowes Z, Belli A, Su Z, Sitaraman M, Davies D, Taylor R, Flahive E, Travis C, O'Neil N, Pettigrew Y. The Development and Psychometric Evaluation of a Supplementary Index Score of the Neuropsychological Assessment Battery Screening Module that is Sensitive to Traumatic Brain Injury. Arch Clin Neuropsychol. 2017 Mar 1;32(2):215-227. doi: 10.1093/arclin/acw087.

Hampson P, Dinsdale RJ, Wearn CM, Bamford AL, Bishop JRB, Hazeldine J, Moiemen NS, Harrison P, Lord JM. Neutrophil Dysfunction, Immature Granulocytes, and Cell-free DNA are Early Biomarkers of Sepsis in Burn-injured Patients: A Prospective Observational Cohort Study. Ann Surg. 2017 Jun;265(6):1241-1249. doi: 10.1097/SLA.0000000000001807.

Hazeldine J, Naumann DN, Toman E, Davies D, Bishop JRB, Su Z, Hampson P, Dinsdale RJ, Crombie N, Duggal NA, Harrison P, Belli A, Lord JM. Prehospital immune responses and development of multiple organ dysfunction syndrome following traumatic injury: A prospective cohort study. PLoS Med. 2017 Jul 18;14(7):e1002338. doi: 10.1371/journal.pmed.1002338.

Hill LJ, Di Pietro V, Hazeldine J, Davies D, Toman E, Logan A, Belli A. Cystatin D (CST5): An ultra-early inflammatory biomarker of traumatic brain injury. Sci Rep. 2017 Jul 10;7(1):5002. doi: 10.1038/s41598-017-04722-5.

Jones LL, Calvert M, Moiemen N, Deeks JJ, Bishop J, Kinghorn P, Mathers J; PEGASUS team. Outcomes important to burns patients during scar management and how they compare to the concepts captured in burn-specific patient reported outcome measures. Burns. 2017 Dec;43(8):1682-1692. doi: 10.1016/j.burns.2017.09.004.

Kozielewicz, P., Alomar, H., Yusof, S., Grafton, G., Cooper, A.J., Curnow, S.J., Ironside, J.W., Pall, H., Barnes, N.M. N-glycosylation and expression in human tissues of the orphan GPR61 receptor. FEBS Open Bio. 7, 1982-1993, 2017.

Kuravi SJ, Yates CM, Foster M, Harrison P, Hazeldine J, Hampson P, Watson C, Belli A, Midwinter M, Nash GB. Changes in the pattern of plasma extracellular vesicles after severe trauma. PLoS One. 2017 Aug 24;12(8):e0183640. doi: 10.1371/journal.pone.0183640.

Maas AIR, Menon DK, Adelson PD, Andelic N, Bell MJ, Belli A, Bragge P, Brazinova A, Büki A, Chesnut RM, Citerio G, Coburn M, Cooper DJ, Crowder AT, Czeiter E, Czosnyka M, Diaz-Arrastia R, Dreier JP, Duhaime AC, Ercole A, van Essen TA, Feigin VL, Gao G, Giacino J, Gonzalez-Lara LE, Gruen RL, Gupta D, Hartings JA, Hill S, Jiang JY, Ketharanathan N, Kompanje EJO, Lanyon L, Laureys S, Lecky F, Levin H, Lingsma HF, Maegele M, Majdan M, Manley G, Marsteller J, Mascia L, McFadyen C, Mondello S, Newcombe V, Palotie A, Parizel PM, Peul W, Piercy J, Polinder S, Puybasset L, Rasmussen TE, Rossaint R, Smielewski P, Söderberg J, Stanworth SJ, Stein MB, von Steinbüchel N, Stewart W, Steyerberg EW, Stocchetti N, Synnot A, Te Ao B, Tenovuo O, Theadom A, Tibboel D, Videtta W, Wang KKW, Williams WH, Wilson L, Yaffe K; InTBIR Participants and Investigators. Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research. Lancet Neurol. 2017 Dec;16(12):987-1048. doi: 10.1016/S1474-4422(17)30371-X.

Martin YH, Jubin K, Smalley S, Wong JP, Brown RA, Metcalfe AD (2017). A novel system for expansion and delivery of human keratinocytes for the treatment of severe cutaneous injuries using microcarriers and compressed collagen. J Tissue Eng Regen Med. 2017. doi: 10.1002/term.2220.

Naumann DN, Hazeldine J, Davies DJ, Bishop J, Midwinter MJ, Belli A, Harrison P, Lord JM (2017) Endotheliopathy of Trauma is an On-Scene Phenomenon, and is Associated with Multiple Organ Dysfunction Syndrome: A Prospective Observational Study. Shock. Sep 22. doi: 10.1097/SHK.0000000000000999.

Naumann DN, Hazeldine J, Dinsdale RJ, Bishop JR, Midwinter MJ, Harrison P, Hutchings SD, Lord JM. Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study. PLoS One. 2017 Dec 19;12(12):e0189870. doi: 10.1371/journal.pone.0189870.

Naumann DN, Hazeldine J, Midwinter MJ, Hutchings SD, Harrison P. (2017) Poor microcirculatory flow dynamics are associated with endothelial cell damage and glycocalyx shedding following traumatic hemorrhagic shock. J Trauma Acute Care Surg. doi: 10.1097/TA.0000000000001695

Roper LS, Nightingale P, Su Z, Mitchell JL, Belli A, Sinclair AJ. Disability from posttraumatic headache is compounded by coexisting posttraumatic stress disorder. J Pain Res. 2017 Aug 21;10:1991-1996. doi: 10.2147/JPR.S129808.

Sii F, Barry RJ, Abbott J, Blanch RJ, MacEwen CJ, Shah P. The UK Paediatric Ocular Trauma Study 1 (POTS1): development of a global standardized protocol for prospective data collection in pediatric ocular trauma. Clin Ophthalmol. 2017 Feb 23;11: 449–452.

Tan CL, Alavi SA, Baldeweg SE, Belli A, Carson A, Feeney C, Goldstone AP, Greenwood R, Menon DK, Simpson HL, Toogood AA, Gurnell M, Hutchinson PJ. The screening and management of pituitary dysfunction following traumatic brain injury in adults: British Neurotrauma Group guidance. J Neurol Neurosurg Psychiatry. 2017 Nov;88(11):971-981. doi: 10.1136/jnnp-2016-315500.

Thomas CN, Berry M, Logan A, Blanch RJ, Ahmed Z. Caspases in retinal ganglion cell death and axon regeneration. Cell Death Discov. 2017 Jul 3;3:17032. doi: 10.1038/cddiscovery.2017.32.

Toman E, Bishop JR, Davies DJ, Su Z, Criseno S, Mason A, Toogood AA, Belli A. Vitamin D Deficiency in Traumatic Brain Injury and Its Relationship with Severity of Injury and Quality of Life: A Prospective, Observational Study. J Neurotrauma. 2017 Apr 1;34(7):1448-1456. doi: 10.1089/neu.2016.4494.

2011-2016

2016

Amorini AM, Lazzarino G, Di Pietro V, Signoretti S, Lazzarino G, Belli A, Tavazzi B. Metabolic, enzymatic and gene involvement in cerebral glucose dysmetabolism after traumatic brain injury. Biochim Biophys Acta. 2016 Apr;1862(4):679-687. doi: 10.1016/j.bbadis.2016.01.023.

Andreeta F, Carboni L, Grafton, G, Jeggo R, Whyment AD, van den TopM, HoyerD, Spanswick D, Barnes NM.Hippocampal 5-HT7 receptors signal phosphorylation of the GluA1 subunit to facilitate AMPA receptor mediated neurotransmission in vitro and in vivo. Br J Pharmacol 173, 1438-1451, 2016.

Berry M, Ahmed Z, Morgan-Warren P, Fulton D, Logan A. Prospects for mTOR-mediated functional repair after central nervous system trauma. Neurobiol Dis. 2016 Jan;85:99-110. doi: 10.1016/j.nbd.2015.10.002.

Hampson P, Dinsdale R, Wearn CJ, Hazeldine J, Moiemen N, Lord J, Harrison P. (2016) Neutrophil dysfunction, immature granulocytes and cell-free DNA are early biomarkers of sepsis in burn injured patients: A prospective observational cohort study. Annals of Surgery.

Hazeldine J, Hampson P, Lord JM. The diagnostic and prognostic value of systems biology research in major traumatic and thermal injury: a review. Burns Trauma. 2016 Sep 21;4:33. doi: 10.1186/s41038-016-0059-3.

Hill LJ, Ahmed Z, Logan A. Decorin treatment for reversing trabecular meshwork fibrosis in open-angle glaucoma. Neural Regen Res. 2016 Jun;11(6):922-3. doi: 10.4103/1673-5374.184489.

Hutchinson PJ, Kolias AG, Timofeev IS, Corteen EA, Czosnyka M, Timothy J, Anderson I, Bulters DO, Belli A, Eynon CA, Wadley J, Mendelow AD, Mitchell PM, Wilson MH, Critchley G, Sahuquillo J, Unterberg A, Servadei F, Teasdale GM, Pickard JD, Menon DK, Murray GD, Kirkpatrick PJ; RESCUEicp Trial Collaborators. Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension. N Engl J Med. 2016 Sep 22;375(12):1119-30. doi: 10.1056/NEJMoa1605215.

Joanna Sajkowska-Kozielewicz, Pawel Kozielewicz, Nicholas M. Barnes, Iwona Wawer and Katarzyna Paradowska. Antioxidant, cytotoxic and anti-proliferative activities and total polyphenol contents of the extracts of Geissospermum reticulatum bark. Oxid Med Cell Longev doi: 10.1155/2016/2573580.

Lee KC, Dretzke J, Grover L, Logan A, Moiemen N. A systematic review of objective burn scar measurements. Burns Trauma. 2016 Apr 27;4:14. doi: 10.1186/s41038-016-0036-x.

Mahmood A, Roberts I, Shakur H, Harris T, Belli A. Does tranexamic acid improve outcomes in traumatic brain injury? BMJ. 2016 Sep 28;354:i4814. doi: 10.1136/bmj.i4814.

Powell AD, Grafton G, Roberts A, Larkin S, O’Neill N, Palandri J, Barnes NM. Novel mechanism of modulation at a ligand-gated ion channel; action of Cl-indole at the 5-HT3A receptor. Br J Pharmacol 173, 3467-3479, 2016.

Morgan-Warren PJ, O'Neill J, de Cogan F, Spivak I, Ashush H, Kalinski H, Ahmed Z, Berry M, Feinstein E, Scott RA, Logan A. siRNA-Mediated Knockdown of the mTOR Inhibitor RTP801 Promotes Retinal Ganglion Cell Survival and Axon Elongation by Direct and Indirect Mechanisms. Invest Ophthalmol Vis Sci. 2016 Feb;57(2):429-43. doi: 10.1167/iovs.15-17511.

Sadideen H, Wilson D, Moiemen N, Kneebone R. Using "The Burns Suite" as a Novel High Fidelity Simulation Tool for Interprofessional and Teamwork Training. J Burn Care Res. 2016 Jul-Aug;37(4):235-42. doi: 10.1097/BCR.0000000000000262.

Staruch RM, Jackson PC, Hodson J, Yim G, Foster MA, Cubison T, Jeffery SL. Comparing the surgical timelines of military and civilians traumatic lower limb amputations. Ann Med Surg (Lond). 2016 Feb 15;6:81-6. doi: 10.1016/j.amsu.2016.02.008.

Vigneswara V, Ahmed Z. Long-term neuroprotection of retinal ganglion cells by inhibiting caspase-2. Cell Death Discov. 2016 Jun 13;2:16044. doi: 10.1038/cddiscovery.2016.44.

Wu F, Young K, Shahid M, Nightingale P, Choudhary S, Craigen M, Jose R, Foster M. Stability of Unicortical versus Bicortical Metacarpal Fracture Internal Fixation Trial (SUBMIT): study protocol for a randomized controlled trial. Trials. 2016 Aug 18;17:411. doi: 10.1186/s13063-016-1538-3.

2015

Davies DJ, Su Z, Clancy MT, Lucas SJ, Dehghani H, Logan A, Belli A. Near-Infrared Spectroscopy in the Monitoring of Adult Traumatic Brain Injury: A Review. J Neurotrauma. 2015 Jul 1;32(13):933-41. doi: 10.1089/neu.2014.3748.

Di Pietro V, Amorini AM, Lazzarino G, Yakoub KM, D'Urso S, Lazzarino G, Belli A. S100B and Glial Fibrillary Acidic Protein as Indexes to Monitor Damage Severity in an In Vitro Model of Traumatic Brain Injury. Neurochem Res. 2015 May;40(5):991-9. doi: 10.1007/s11064-015-1554-9.

Hazeldine J, Lord JM, Belli A. Traumatic Brain Injury and Peripheral Immune Suppression: Primer and Prospectus. Front Neurol. 2015 Nov 5;6:235. doi: 10.3389/fneur.2015.00235.

Hazeldine J, Hampson P, Opoku FA, Foster M, Lord JM. N-Formyl peptides drive mitochondrial damage associated molecular pattern induced neutrophil activation through ERK1/2 and P38 MAP kinase signalling pathways. Injury. 2015;46(6):975-84. doi: 10.1016/j.injury.2015.03.028.

Hazeldine J, Lord JM, Hampson P. Immunesenescence and inflammaging: A contributory factor in the poor outcome of the geriatric trauma patient. Ageing Res Rev. 2015 Nov;24(Pt B):349-57. doi: 10.1016/j.arr.2015.10.003.

Hill LJ, Mead B, Blanch RJ, Ahmed Z, De Cogan F, Morgan-Warren PJ, Mohamed S, Leadbeater W, Scott RA, Berry M, Logan A. Decorin Reduces Intraocular Pressure and Retinal Ganglion Cell Loss in Rodents Through Fibrolysis of the Scarred Trabecular Meshwork. Invest Ophthalmol Vis Sci. 2015 Jun;56(6):3743-57. doi: 10.1167/iovs.14-15622.

Kwei J, Halstead FD, Dretzke J, Oppenheim BA, Moiemen NS. Protocol for a systematic review of quantitative burn wound microbiology in the management of burns patients. Syst Rev. 2015 Nov 6;4:150. doi: 10.1186/s13643-015-0137-9.

Park MS, Xue A, Spears GM, Halling TM, Ferrara MJ, Kuntz MM, Dhillon SK, Jenkins DH, Harmsen WS, Ballman KV, Harrison P, Heit JA. Thrombin generation and procoagulant microparticle profiles after acute trauma: A prospective cohort study. J Trauma Acute Care Surg. 2015 Nov;79(5):726-31. doi: 10.1097/TA.0000000000000839.

Penn-Barwell JG, Myatt RW, Bennett PM, Sargeant ID; Severe Lower Extremity Combat Trauma (SeLECT) Study Group. Medium-term outcomes following limb salvage for severe open tibia fracture are similar to trans-tibial amputation. Injury. 2015 Feb;46(2):288-91. doi: 10.1016/j.injury.2014.12.004.

Tsermoulas G, Shah O, Wijesinghe HE, Silva AHD, Ramalingam SK, Belli A. Surgery for Acute Subdural Hematoma: Replace or Remove the Bone Flap? World Neurosurg. 2016 Apr;88:569-575. doi: 10.1016/j.wneu.2015.10.045.

Vigneswara V, Esmaeili M, Deer L, Berry M, Logan A, Ahmed Z. Eye drop delivery of pigment epithelium-derived factor-34 promotes retinal ganglion cell neuroprotection and axon regeneration. Mol Cell Neurosci. 2015 Sep;68:212-21. doi: 10.1016/j.mcn.2015.08.001.

Wearn C, Hardwicke J, Kitsios A, Siddons V, Nightingale P, Moiemen N. Outcomes of burns in the elderly: revised estimates from the Birmingham Burn Centre. Burns. 2015 Sep;41(6):1161-8. doi: 10.1016/j.burns.2015.04.008.

Wearn CM, Hardwicke J, Moiemen N. Burns in the elderly: Mortality is still a relevant outcome. Burns. 2015 Nov;41(7):1617-8. doi: 10.1016/j.burns.2015.08.029.

2014

Ahmed Z, Bansal D, Tizzard K, Surey S, Esmaeili M, Gonzalez AM, Berry M, Logan A. Decorin blocks scarring and cystic cavitation in acute and induces scar dissolution in chronic spinal cord wounds. Neurobiol Dis. 2014 Apr;64:163-76. doi: 10.1016/j.nbd.2013.12.008. Epub 2013 Dec 31.

Andrews NA, Papakosta M, Barnes NM. Discovery of novel anxiolytic agents - The trials and tribulations of pre-clinical models of anxiety. Neurobiol Dis 61:72-78, 2014.

Blanch RJ, Ahmed Z, Thompson AR, Akpan N, Snead DR, Berry M, Troy CM, Scott RA, Logan A. Caspase-9 mediates photoreceptor death after blunt ocular trauma. Invest Ophthalmol Vis Sci. 2014 Sep 4;55(10):6350-7. doi: 10.1167/iovs.13-13708.

Bulstrode H, Nicoll JA, Hudson G, Chinnery PF, Di Pietro V, Belli A. Mitochondrial DNA and traumatic brain injury. Ann Neurol. 2014 Feb;75(2):186-95. doi: 10.1002/ana.24116.

Di Pietro V, Lazzarino G, Amorini AM, Tavazzi B, D'Urso S, Longo S, Vagnozzi R, Signoretti S, Clementi E, Giardina B, Lazzarino G, Belli A. Neuroglobin expression and oxidant/antioxidant balance after graded traumatic brain injury in the rat. Free Radic Biol Med. 2014 Apr;69:258-64. doi: 10.1016/j.freeradbiomed.2014.01.032.

Di Pietro V, Amorini AM, Tavazzi B, Vagnozzi R, Logan A, Lazzarino G, Signoretti S, Lazzarino G, Belli A. The molecular mechanisms affecting N-acetylaspartate homeostasis following experimental graded traumatic brain injury. Mol Med. 2014 Mar 24;20(1):147-57. doi: 10.2119/molmed.2013.00153.

El Ghoul W, Harrisson S, Belli A. Autologous cranioplasty following decompressive craniectomy in the trauma setting. Br J Neurosurg. 2015 Feb;29(1):64-69. doi: 10.3109/02688697.2014.957157.

Hall S, Kumaria A, Belli A. The role of vagus nerve overactivity in the increased incidence of pneumonia following traumatic brain injury. Br J Neurosurg. 2014 Apr;28(2):181-6. doi: 10.3109/02688697.2013.835373.

Hardwicke JT, Tan JJ, Foster MA, Titley OG. A systematic review of 2-strand versus multistrand core suture techniques and functional outcome after digital flexor tendon repair. J Hand Surg Am. 2014 Apr;39(4):686-695.e2. doi: 10.1016/j.jhsa.2013.12.037.

Hazeldine J, Hampson P, Lord JM. The impact of trauma on neutrophil function. Injury. 2014 Dec;45(12):1824-33. doi: 10.1016/j.injury.2014.06.021.

Jackson PC, Foster M, Fries A, Jeffery SL. Military trauma care in Birmingham: observational study of care requirements and resource utilisation. Injury. 2014 Jan;45(1):44-9. doi: 10.1016/j.injury.2012.08.036.

Jackson PC, Hardwicke J, Bamford A, Nightingale P, Wilson Y, Papini R, Moiemen N. Revised estimates of mortality from the Birmingham Burn Centre, 2001-2010: a continuing analysis over 65 years. Ann Surg. 2014 May;259(5):979-84. doi: 10.1097/SLA.0b013e31829160ca.

Langschmidt J, Caine PL, Wearn CM, Bamford A, Wilson YT, Moiemen NS. Hydrotherapy in burn care: a survey of hydrotherapy practices in the UK and Ireland and literature review. Burns. 2014 Aug;40(5):860-4. doi: 10.1016/j.burns.2013.11.006.

Lee KC, Joory K, Moiemen NS. History of burns: The past, present and the future. Burns Trauma. 2014 Oct 25;2(4):169-80. doi: 10.4103/2321-3868.143620.

Lord JM, Midwinter MJ, Chen YF, Belli A, Brohi K, Kovacs EJ, Koenderman L, Kubes P, Lilford RJ. The systemic immune response to trauma: an overview of pathophysiology and treatment. Lancet. 2014 Oct 18;384(9952):1455-65. doi: 10.1016/S0140-6736(14)60687-5.

Mishra A, Chawla R, Foster M, Power D. Improving outcomes following peripheral nerve injury: national standards, education and training in the U.K. Hand Surg. 2014;19(3):491-2. doi: 10.1142/S0218810414820012.

Rassul SM, Neely RK, Fulton D. Live-imaging in the CNS: New insights on oligodendrocytes, myelination, and their responses to inflammation. Neuropharmacology. 2016 Nov;110(Pt B):594-604. doi: 10.1016/j.neuropharm.2015.09.011.

Sadideen H, Wilson D, Moiemen N, Kneebone R. Proposing "the burns suite" as a novel simulation tool for advancing the delivery of burns education. J Burn Care Res. 2014 Jan-Feb;35(1):62-71. doi: 10.1097/BCR.0b013e31829b371d.

Surey S, Berry M, Logan A, Bicknell R, Ahmed Z. Differential cavitation, angiogenesis and wound-healing responses in injured mouse and rat spinal cords. Neuroscience. 2014 Sep 5;275:62-80. doi: 10.1016/j.neuroscience.2014.06.003.

Stover JF, Belli A, Boret H, Bulters D, Sahuquillo J, Schmutzhard E, Zavala E, Ungerstedt U, Schinzel R, Tegtmeier F; NOSTRA Investigators. Nitric oxide synthase inhibition with the antipterin VAS203 improves outcome in moderate and severe traumatic brain injury: a placebo-controlled randomized Phase IIa trial (NOSTRA). J Neurotrauma. 2014 Oct 1;31(19):1599-606. doi: 10.1089/neu.2014.3344.

Upthegrove R, Manzanares-Teson N, Barnes NM. Cytokine function in medication-naïve first episode psychosis: a systematic review and meta-analysis. Schizophrenia Res 155, 101-108, 2014.

Vigneswara V, Akpan N, Berry M, Logan A, Troy CM, Ahmed Z. Combined suppression of CASP2 and CASP6 protects retinal ganglion cells from apoptosis and promotes axon regeneration through CNTF-mediated JAK/STAT signalling. Brain. 2014 Jun;137(Pt 6):1656-75. doi: 10.1093/brain/awu037.

2013

Ahmed Z, Douglas MR, John G, Berry M, Logan A. AMIGO3 is an NgR1/p75 co-receptor signalling axon growth inhibition in the acute phase of adult central nervous system injury. PLoS One. 2013 Apr 16;8(4):e61878. doi: 10.1371/journal.pone.0061878.

Andreetta F, Barnes NM, Wren PB, Carboni L. p38 MAP kinase activation does not stimulate serotonin transport in rat brain: Implications for sickness behaviour mechanisms. Life Sci. 19, 30-37, 2013.

Di Pietro V, Amorini AM, Tavazzi B, Hovda DA, Signoretti S, Giza CC, Lazzarino G, Vagnozzi R, Lazzarino G, Belli A. Potentially neuroprotective gene modulation in an in vitro model of mild traumatic brain injury. Mol Cell Biochem. 2013 Mar;375(1-2):185-98. doi: 10.1007/s11010-012-1541-2.

Fraise AP, Wilkinson MA, Bradley CR, Oppenheim B, Moiemen N. The antibacterial activity and stability of acetic acid. J Hosp Infect. 2013 Aug;84(4):329-31. doi: 10.1016/j.jhin.2013.05.001.

Hardwicke J, Thomson R, Bamford A, Moiemen N. A pilot evaluation study of high resolution digital thermal imaging in the assessment of burn depth. Burns. 2013 Feb;39(1):76-81. doi: 10.1016/j.burns.2012.03.014.

Hardwicke J, Bechar J, Bella H, Moiemen N. Cutaneous chemical burns in children - a comparative study. Burns. 2013 Dec;39(8):1626-30. doi: 10.1016/j.burns.2013.04.005.

Hou R, Moss-Morris R, Peveler R, Mogg K, Bradley BP, Belli A. When a minor head injury results in enduring symptoms: a prospective investigation of risk factors for postconcussional syndrome after mild traumatic brain injury. J Neurol Neurosurg Psychiatry. 2012 Feb;83(2):217-23. doi: 10.1136/jnnp-2011-300767.

Kolias AG, Bulters DO, Cowie CJ, Wilson MH, Afshari FT, Helmy A, Broughton E, Joannides AJ, Zebian B, Harrisson SE, Hill CS, Ahmed AI, Barone DG, Thakur B, McMahon CJ, Adlam DM, Bentley RP, Tolias CM, Mitchell PM, Whitfield PC, Critchley GR, Belli A, Brennan PM, Hutchinson PJ; British Neurosurgical Trainee Research Collaborative; British Neurotrauma Group; UKCRR Collaborative Group. Proposal for establishment of the UK Cranial Reconstruction Registry (UKCRR). Br J Neurosurg. 2014 Jun;28(3):310-4. doi: 10.3109/02688697.2013.859657.

Kundi S, Bicknell R, Ahmed Z. The role of angiogenic and wound-healing factors after spinal cord injury in mammals. Neurosci Res. 2013 May-Jun;76(1-2):1-9. doi: 10.1016/j.neures.2013.03.013.

Morgan-Warren PJ, Berry M, Ahmed Z, Scott RA, Logan A Exploiting mTOR signaling: a novel translatable treatment strategy for traumatic optic neuropathy?. Invest Ophthalmol Vis Sci. 2013 Oct 23;54(10):6903-16. doi: 10.1167/iovs.13-12803. Review.

Vagnozzi R, Signoretti S, Floris R, Marziali S, Manara M, Amorini AM, Belli A, Di Pietro V, Dʼurso S, Pastore FS, Lazzarino G, Tavazzi B. Decrease in N-acetylaspartate following concussion may be coupled to decrease in creatine. J Head Trauma Rehabil. 2013 Jul-Aug;28(4):284-92. doi: 10.1097/HTR.0b013e3182795045.

Vigneswara V, Berry M, Logan A, Ahmed Z. Caspase-2 is upregulated after sciatic nerve transection and its inhibition protects dorsal root ganglion neurons from apoptosis after serum withdrawal. PLoS One. 2013;8(2):e57861. doi: 10.1371/journal.pone.0057861. Epub 2013 Feb 25.

Vigneswara V, Berry M, Logan A, Ahmed Z. Pigment epithelium-derived factor is retinal ganglion cell neuroprotective and axogenic after optic nerve crush injury. Invest Ophthalmol Vis Sci. 2013 Apr 12;54(4):2624-33. doi: 10.1167/iovs.13-11803.

2012

Blanch RJ, Ahmed Z, Sik A, Snead DR, Good PA, O'Neill J, Berry M, Scott RA, Logan A. Neuroretinal cell death in a murine model of closed globe injury: pathological and functional characterization. Invest Ophthalmol Vis Sci. 2012 Oct 17;53(11):7220-6. doi: 10.1167/iovs.12-9887.

Gheorghe A, Calvert M, Pinkney TD, Fletcher BR, Bartlett DC, Hawkins WJ, Mak T, Youssef H, Wilson S; West Midlands Research Collaborative; ROSSINI Trial Management Group. Systematic review of the clinical effectiveness of wound-edge protection devices in reducing surgical site infection in patients undergoing open abdominal surgery. Ann Surg. 2012 Jun;255(6):1017-29. doi: 10.1097/SLA.0b013e31823e7411.

Hardwicke J, Hunter T, Staruch R, Moiemen N. Chemical burns--an historical comparison and review of the literature. Burns. 2012 May;38(3):383-7. doi: 10.1016/j.burns.2011.09.014.

Jackson PC, Foster MA, Fries A, Jeffery SLA. Military trauma care in Birmingham: observational study of care requirements and resource utilisation. Injury. 2014 Jan;45(1):44-9. doi: 10.1016/j.injury.2012.08.036.

Jacques SJ, Ahmed Z, Forbes A, Douglas MR, Vigenswara V, Berry M, Logan A. AAV8(gfp) preferentially targets large diameter dorsal root ganglion neurones after both intra-dorsal root ganglion and intrathecal injection. Mol Cell Neurosci. 2012 Apr;49(4):464-74. doi: 10.1016/j.mcn.2012.03.002.

Vigneswara V, Berry M, Logan A, Ahmed Z. Pharmacological inhibition of caspase-2 protects axotomised retinal ganglion cells from apoptosis in adult rats. PLoS One. 2012;7(12):e53473. doi: 10.1371/journal.pone.0053473.

Vigneswara V, Kundi S, Ahmed Z. Receptor tyrosine kinases: molecular switches regulating CNS axon regeneration. J Signal Transduct. 2012;2012:361721. doi: 10.1155/2012/361721.

2011

Ahmed Z, Douglas MR, Read ML, Berry M, Logan A. Citron kinase regulates axon growth through a pathway that converges on cofilin downstream of RhoA. Neurobiol Dis. 2011 Feb;41(2):421-9. doi: 10.1016/j.nbd.2010.10.012.

Ahmed Z, Kalinski H, Berry M, Almasieh M, Ashush H, Slager N, Brafman A, Spivak I, Prasad N, Mett I, Shalom E, Alpert E, Di Polo A, Feinstein E, Logan A.Ocular neuroprotection by siRNA targeting caspase-2. Cell Death Dis. 2011 Jun 16;2:e173. doi: 10.1038/cddis.2011.54.

Berry M, Ahmed Z, Douglas MR, Logan A. Epidermal growth factor receptor antagonists and CNS axon regeneration: mechanisms and controversies. Brain Res Bull. 2011 Mar 10;84(4-5):289-99. doi: 10.1016/j.brainresbull.2010.08.004.

Foster MA, Moledina J, Jeffery SLA. Epidemiology of UK military burns. J Burn Care Res. 2011 May-Jun;32(3)415-20. doi:10.1097/BCR.0b013e318217fa13.

Moiemen NS, Shale E, Drysdale KJ, Smith G, Wilson YT, Papini R. Acticoat dressings and major burns: systemic silver absorption. Burns. 2011 Feb;37(1):27-35. doi: 10.1016/j.burns.2010.09.006.

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