No other health condition matches mental illness in the combined extent of prevalence, persistence and breadth of impact.
Approximately 75% of lifelong mental health disorders begin before the age of 24. With mental health disorders in young people and adolescents increasing, the focus of the Institute for Mental Health will be to improve the care of young people with mental health problems and to improve the services available to them.
The Institute for Mental Health (IMH) has been established to maximise the collaborative efforts of academics at the University of Birmingham, and builds on the strong existing partnerships with practice in the NHS; established through Birmingham Health Partners, Forward Thinking Birmingham, and Birmingham and Solihull Mental Health NHS Foundation Trust.
Through interdisciplinary research the IMH works to improve the outcomes and care for young people with mental health problems. We will do this by working together to understand the causes of poor mental health, prevent mental health problems from developing, and respond to established illness by developing new treatments and services.
Research Outputs
Article
Allott, K, Chopra, S, Rogers, J, Dauvermann, MR & Clark, SR 2024, 'Advancing understanding of the mechanisms of antipsychotic-associated cognitive impairment to minimise harm: a call to action', Molecular Psychiatry. https://doi.org/10.1038/s41380-024-02503-x
Hoheisel, L, Kambeitz-Ilankovic, L, Wenzel, J, Haas, SS, Antonucci, LA, Ruef, A, Penzel, N, Schultze-Lutter, F, Lichtenstein, T, Rosen, M, Dwyer, DB, Salokangas, RKR, Lencer, R, Brambilla, P, Borgwardt, S, Wood, SJ, Upthegrove, R, Bertolino, A, Ruhrmann, S, Meisenzahl, E, Koutsouleris, N, Fink, GR, Daun, S & Kambeitz, J 2024, 'Alterations of Functional Connectivity Dynamics in Affective and Psychotic Disorders', Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. https://doi.org/10.1016/j.bpsc.2024.02.013
Lalousis, PA, Malaviya, A, Khatibi, A, Saberi, M, Kambeitz-Ilankovic, L, Haas, SS, Wood, SJ, Barnes, NM, Rogers, J, Chisholm, K, Bertolino, A, Borgwardt, S, Brambilla, P, Kambeitz, J, Lencer, R, Pantelis, C, Ruhrmann, S, Salokangas, RKR, Schultze-Lutter, F, Schmidt, A, Meisenzahl, E, Dwyer, D, Koutsouleris, N, Upthegrove, R, Griffiths, SL & PRONIA Consortium 2024, 'Anhedonia as a potential transdiagnostic phenotype with immune-related changes in recent onset mental health disorders', Biological Psychiatry. https://doi.org/10.1016/j.biopsych.2024.05.019
Contreras-Huerta, LS, Pisauro, MA, Küchenhoff, S, Gekiere, A, Le Heron, C, Lockwood, PL & Apps, MAJ 2024, 'A reward self-bias leads to more optimal foraging for ourselves than others', Scientific Reports, vol. 14, no. 1, 26845. https://doi.org/10.1038/s41598-024-69452-x
Tse, W, Khandaker, GM, Zhou, H, Luo, H, Yan, WC, Siu, MW, Poon, LT, Lee, EHM, Zhang, Q, Upthegrove, R, Osimo, EF, Perry, BI & Chan, SKW 2024, 'Assessing the generalisability of the psychosis metabolic risk calculator (PsyMetRiC) for young people with first-episode psychosis with validation in a Hong Kong Chinese Han population: a 4-year follow-up study', The Lancet Regional Health - Western Pacific, vol. 47, 101089. https://doi.org/10.1016/j.lanwpc.2024.101089
Comment/debate
ISARIC4C Investigators, COVID-CNS Consortium, Michael, BD, Dunai, C, Needham, EJ, Tharmaratnam, K, Williams, R, Huang, Y, Boardman, SA, Clark, JJ, Sharma, P, Subramaniam, K, Wood, GK, Collie, C, Digby, R, Ren, A, Norton, E, Leibowitz, M, Ebrahimi, S, Fower, A, Fox, H, Tato, E, Ellul, MA, Sunderland, G, Held, M, Hetherington, C, Egbe, FN, Palmos, A, Stirrups, K, Grundmann, A, Chiollaz, AC, Sanchez, JC, Stewart, JP, Griffiths, M, Solomon, T, Breen, G, Coles, AJ, Kingston, N, Bradley, JR, Chinnery, PF, Cavanagh, J, Irani, SR, Vincent, A, Baillie, JK, Openshaw, PJ, Semple, MG, Taams, LS & Menon, DK 2024, 'Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses', Nature Communications, vol. 15, no. 1, 2918. https://doi.org/10.1038/s41467-024-47320-6
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