Cancer Immunology and Immunotherapy

Cancer Immunology is one of three research domains within the successful CRUK Centre award of 2017 and the Centre for Immunology and Immunotherapy of Cancer (CIIC), a University of Birmingham-wide grouping facilitating cross-Department/cross-College development of this theme, has been active since 2012.

Our aim is to make significant contributions to understanding the fundamental processes that underlie the immune response to cancer and to translate this into therapeutic opportunities with our NHS partners. Our plans will see us strengthen national and international collaborations, deepen our interactions with industry and contribute to training within this exciting area of biology.

Cancer Immunology and Immunotherapy Principal Investigators

Principal Investigator	Research Interest
Professor Benjamin Willcox	Novel tumour antigens and unconventional T cell function, particularly in immunosurveillance of cellular stress.
Professor Gary Middleton	Tumour immunobiology and the tumour microenviroment with a particular focus on MDSCs.
Professor Paul Moss	Application of translational immunological research in the study of human disease.
Dr Yuk Ting Ma	Understanding how epigenetic therapies may be used to reverse resistance to chemotherapy.
Dr Graham Taylor	Immune system in health and disease and how best to harness the immune system to treat cancer.
Dr Claire Shannon-Lowe	Epstein-Barr virus (EBV) entry into epithelial cells, T cells and Natural Killer cells.
Dr Heather Long	Developing immune-based therapies for the treatment of EBV-associated and non virus-associated lymphomas.
Dr Fiyaz Mohammed	Immune cell surface receptor/ligand interactions relevant to cancer using X-ray crystallography.
Dr Jianmin Zuo	Natural Killer (NK) cells in leukaemia.
Dr Carmela De Santo	Tumour immunosuppression and myeloid derived suppressor cells.