Substantial Amendment 18

Please ensure that you have obtained local R&D approval for this amendment before using these documents. All documents require a username and password login to access; please contact the Trial Office if you require these. 

  • National Lung Matrix Trial Protocol vn8.0 18-Oct-2019 [PDF, 4,681KB]
  • National Lung Matrix Trial - Protocol Synopsis v8.0_18-Oct-2019 [PDF, 143KB]
  • SA18 MHRA Approval Docs v1.0_11-Dec-2019 [PDF, 313KB]
  • SA18 HRA Appoval Docs v1.0_07-Jan-2020 [PDF, 343KB]
  • SA18 REC Approval Docs v2.0_22-Apr-2020 [PDF, 758KB]
  • Amendment Form MHRA Eudract Ready For Submission 30-Oct-2019 [PDF, 261KB]
  • FDA safety alert 13-Sep-2019 [PDF, 72KB]
  • Pfizer guidance for ILD pneumonitis 06-Sep-2019 [PDF, 38KB]
  • National Lung Matrix Trial ArmC Palbociclib PIS+ICF vn8.0 29-Oct-2019 [Word, 250KB]
  • NLMT PIS & ICF Addendum D Arm C v2.0_05-Dec-2019 [Word, 839KB]