Substantial Amendment 16 Back to 'For participating sites' All documents are pdf unless otherwise specified and require username and password login to access. SA16 MHRA Approval Documents Bundle [pdf 126 KB] SA16 HRA Approval Documents Bundle [pdf 116 KB] SA16 REC Approval Documents Bundle [pdf 212 KB] National Lung Matrix Trial Protocol vn7.0 18-Jun-2019 [pdf 4,138 KB] National Lung Matrix Trial Protocol Synopsis v7.0 18-Jun-2019 [pdf 496 KB]