Amendments

Substantial Amendments

• Amendment 1 20-Jul-2012 - Protocol v2 following MHRA approval
  • Ethics Approval [.pdf]
• Amendment 2 06-Sep-2012 - Protocol / PIS 
  • Ethics Approval [.pdf]
  • MHRA Approval [.pdf]
• Amendment 3 - Addition of Sites 
• Amendment 4 - Addition of Sites 
• Amendment 5 - Addition of Sites 

• Amendment 6 27-Jun-2013 - Protocol / PIS
  • Ethics Approval [.pdf]
  • MHRA Approval [.pdf]

• Amendment 7 - Addition of Sites 
• Amendment 8 - RSI update
• Amendment 9 - Addition of Sites 

• Amendment 10 22-Nov-2013 - Protocol  
  • Ethics Approval [.pdf]
  • MHRA Approval [.pdf]
• Amendment 11 - Addition of Sites 

• Amendment 12 15-Apr-2014 - Protocol / PIS
  • Ethics Approval [.pdf]
  • MHRA Approval [.pdf]
• Amendment 13 - RSI update
• Amendment 14 - Addition of Sites
• Amendment 15 - NSA protocol v6a
• Amendment 16 -  PI Change
• Amendment 17- Addition of Sites

• Amendment 18 10-Jul-2015 - Protocol / PIS
  • Ethics Approval [.pdf]
  • MHRA Approval [.pdf

Non-Substantial Amendments

Amendment 15 18-Sep-2014 - Error in Schedule of assessments corrected