CEDAM publications

Below is a list of the latest publications by CEDAM

Gorvin CM. Recent advances in calcium-sensing receptor structures and signaling pathways. In Progress in Molecular Biology and Translational Science. 2023 doi: 10.1016/bs.pmbts.2022.06.014

Mollan S, Subramanian A, Perrins M, Nirantharakumar K, Adderley N, Sinclair A. Depression and anxiety in women with idiopathic intracranial hypertension compared to migraine: a matched controlled cohort study. Headache. 2023 Feb 7. Epub 2023 Feb 7. doi: 10.1111/head.14465

Mangone A, Altieri B, Detomas M, Prete A, Abbas H, Asia M et al. Inflammation-based scores as predictors of treatment response in advanced adrenocortical carcinoma. Endocrine-related cancer. 2023 Jan 30. doi: 10.1530/ERC-22-0372

Ronchi C. COVID-19-related Adrenal Haemorrhage: Multicentre UK Experience and Systematic Review of the Literature: COVID-19 and Adrenal Haemorrhage. Clinical Endocrinology. 2023 Jan 22.

Schiffer L, Kempegowda P, Sitch AJ, Adaway JE, Shaheen F, Ebbehoj A et al. Classic and 11-oxygenated androgens in serum and saliva across adulthood: a cross-sectional study analyzing the impact of age, body mass index, and diurnal and menstrual cycle variation. European Journal of Endocrinology. 2023 Jan 10;188(1):lvac017. doi: 10.1093/ejendo/lvac017

Ko YL, Kumar V, Lippert J, Diaz-Cano S, Skordilis K, Kimpel O et al. Coincidence of primary adrenocortical carcinoma and melanoma: three CASE reports. BMC Endocrine Disorders. 2023 Jan 6;23:4. doi: 10.1186/s12902-022-01253-7

Eissa AG, Powell L, Gee J, Foster P, Simons C. Pyridine based dual binding site aromatase (CYP19A1) inhibitors. RSC Medicinal Chemistry. 2023 Jan 3. Epub 2023 Jan 3. doi: 10.1039/D2MD00352J

Mollan S, Sinclair A, Tsermoulas G. Letter: Cerebrospinal fluid shunting for idiopathic intracranial hypertension: a systematic review, meta-analysis, and implications for a modern management protocol. Neurosurgery. 2022 Dec 29;10.1227/neu.0000000000002316. Epub 2022 Dec 29. doi: 10.1227/neu.0000000000002316

Mangone A, Yousuf Q, Arlt W, Prete A, Shaheen F, Krishnasamy S-K et al. A case of unilateral post-COVID-19 adrenal haemorrhage and follow-up during pregnancies. Endocrinology, diabetes & metabolism case reports. 2022 Dec 21;2022(1):22-0337. doi: 10.1530/EDM-22-0337

Alimajstorovic Z, Mollan S, Grech O, Mitchell J, Yiangou A, Thaller M et al. Dysregulation of amino acid, lipid and acylpyruvate metabolism in idiopathic intracranial hypertension: a non-targeted case control and longitudinal metabolomic study. Journal of Proteome Research. 2022 Dec 19. Epub 2022 Dec 19. doi: 10.1021/acs.jproteome.2c00449

Lyons H, Ramalingam S, Mitchell J, Yiangou A, Thaller M, Sinclair A et al. Multiple lumbar punctures aiming to relieve headache results in iatrogenic spinal haematoma: a case report. Journal of medical case reports. 2022 Dec 14;16(1):464 . doi: 10.1186/s13256-022-03687-y

Thaller M, Adderley N, Subramanian A, Mollan S, Sinclair A. Comorbid polycystic ovarian syndrome in idiopathic intracranial hypertension. Neuro-Ophthalmology. 2022 Dec 12.

Van Haalen FM, Kaya M, Pelsma ICM, Dekkers OM, Biermasz NR, Cannegieter SC et al. Current clinical practice for thromboprophylaxis management in patients with Cushing’s syndrome across reference centers of the European Reference Network on Rare Endocrine Conditions (Endo-ERN). Orphanet Journal of Rare Diseases. 2022 Dec;17(1):178 . Epub 2022 May 3. doi: 10.1186/s13023-022-02320-x

Gorvin CM, Newey PJ, Thakker R. Identification of prolactin receptor variants with diverse effects on receptor signalling. Journal of Molecular Endocrinology. 2022 Nov 29. doi: 10.1530/JME-22-0164

Hamblin R, Fountas A, Levy MJ, Karavitaki N. UK practice on incidentally detected non-functioning pituitary microadenomas: analysis of two national surveys during a 12-year interval. Pituitary. 2022 Nov 25;2022. Epub 2022 Nov 25. doi: 10.1007/s11102-022-01290-4

Elhassan Y, Ronchi C, Wijewickrama P, Baldeweg SE. Approach to the Patient with Adrenal Hemorrhage. Journal of Clinical Endocrinology and Metabolism. 2022 Nov 21;2022(00):dgac672. Epub 2022 Nov 21. doi: 10.1210/clinem/dgac672

Hansen MS, Søe K, Christensen LL, Fernandez-Guerra P, Hansen NW, Wyatt RA et al. GIP reduces osteoclast activity and improves osteoblast survival in primary human bone cells. European Journal of Endocrinology . 2022 Nov 16;lvac004. doi: 10.1093/ejendo/lvac004

Fountas A, Karavitaki N. Management of Nelson’s syndrome. Medicina. 2022 Nov 2;58(11):1580. doi: 10.3390/medicina58111580

Mitchell J, Buckham R, Lyons H, Walker J, Yiangou A, Sassani M et al. Evaluation of diurnal and postural intracranial pressure employing telemetric monitoring in idiopathic intracranial hypertension. Fluids and barriers of the CNS. 2022 Nov 1;19(1):85. doi: 10.1186/s12987-022-00384-2

GENEVA collaborators, Singhal R, Wiggins T, Pouwels S, Rajeev Y, Madhok B et al. Handling of the Covid-19 Pandemic and Its Effects on Bariatric Surgical Practice: Analysis of GENEVA Study Database. Obesity surgery. 2022 Oct 25. Epub 2022 Oct 25. doi: 10.1007/s11695-022-06267-7

Thaller M, Homer V, Hyder Y, Yiangou A, Liczkowski A, Fong A et al. The idiopathic intracranial hypertension prospective cohort study: evaluation of prognostic factors and outcomes. Journal of Neurology. 2022 Oct 15. Epub 2022 Oct 15. doi: 10.1007/s00415-022-11402-6

Dohle W, Asiki H, Gruchot W, Foster P, Sahota H, Bai R et al. 2-difluoromethoxy-substituted estratriene sulfamates: synthesis, antiproliferative SAR, antitubulin activity, and steroid sulfatase inhibition. ChemMedChem. 2022 Oct 13;e202200408. Epub 2022 Oct 13. doi: 10.1002/cmdc.202200408

Eissa AG, Barrow D, Gee J, Powell L, Foster P, Simons C. 4th Generation nonsteroidal aromatase inhibitors: An iterative SAR-guided design, synthesis, and biological evaluation towards picomolar dual binding inhibitors. European Journal of Medicinal Chemistry. 2022 Oct 5;240:114569. Epub 2022 Jul 11. doi: 10.1016/j.ejmech.2022.114569

Atila C, Loughrey PB, Garrahy A, Winzeler B, Refardt J, Gildroy P et al. Central diabetes insipidus from a patient's perspective: management, psychological comorbidities, and re-naming of the condition - results from an international web-based survey. The Lancet Diabetes and Endocrinology. 2022 Oct 1;10(10):700-709. Epub 2022 Aug 22. doi: 10.1016/S2213-8587(22)00219-4

International Collaboration of Sleep Apnea Cardiovascular Trialists INCOSACT. Obstructive sleep apnea and its management in patients with atrial fibrillation: an International Collaboration of Sleep Apnea Cardiovascular Trialists (INCOSACT) global survey of practicing cardiologists. International journal of cardiology. Heart & vasculature. 2022 Oct;42:101085. Epub 2022 Jul 19. doi: 10.1016/j.ijcha.2022.101085

Mollan SP, Mitchell JL, Yiangou A, Ottridge RS, Alimajstorovic Z, Cartwright DM et al. Association of amount of weight lost after bariatric surgery with intracranial pressure in women with idiopathic intracranial hypertension. Neurology. 2022 Sep 13;99(11):e1090-e1099. Epub 2022 Jul 5. doi: 10.1212/WNL.0000000000200839

Dobbie LJ, Tahrani A, Alam U, James J, Wilding J, Cuthbertson DJ. Exercise in obesity-the role of technology in health services: can this approach work? Current Obesity Reports. 2022 Sep;11(3):93-106. Epub 2021 Nov 17. doi: 10.1007/s13679-021-00461-x

Bjornsdottir S, Ing S, Mitchell DM, Sikjaer T, Underbjerg L, Hassan‐smith Z et al. Epidemiology and financial burden of adult chronic hypoparathyroidism. Journal of Bone and Mineral Research. 2022 Aug 29;1-13. Epub 2022 Aug 29. doi: 10.1002/jbmr.4675

Khan AA, Bilezikian JP, Brandi ML, Clarke BL, Gittoes NJ, Pasieka JL et al. Evaluation and management of hypoparathyroidism summary statement and guidelines from the Second International Workshop. Journal of Bone and Mineral Research. 2022 Aug 28. Epub 2022 Aug 28. doi: 10.1002/jbmr.4691 

Kanj U, Lee SS, Wattegama M, Chavda S, Karavitaki N, Batra R. Foster Kennedy syndrome secondary to a giant prolactinoma with a remarkable response to cabergoline. Endocrinology, diabetes & metabolism case reports. 2022 Aug 26;2022(1):22-0261. doi: 10.1530/EDM-22-0261

Adderley N, Subramanian A, Perrins M, Nirantharakumar K, Mollan S, Sinclair A. Headache, opiate use, and prescribing trends in women with idiopathic intracranial hypertension: a population-based matched cohort study. Neurology. 2022 Aug 19. Epub 2022 Aug 19. doi: 10.1212/WNL.0000000000201064

Lippert J, Altieri B, Morrison B, Steinhauer S, Smith G, Lorey A et al. Prognostic role of targeted methylation analysis in paraffin-embedded samples of adrenocortical carcinoma. Journal of Clinical Endocrinology and Metabolism. 2022 Aug 4;107(10):1-8. dgac470. doi: 10.1210/clinem/dgac470

Alshehri Z, Subramanian A, Adderley N, Gokhale K, Karamat MA, Ray C et al. Risk of incident obstructive sleep apnoea in patients with type 1 diabetes: a population-based retrospective cohort study. Diabetologia. 2022 Aug;65(8):1353-1363. Epub 2022 May 24. doi: 10.1007/s00125-022-05714-5

Coulden A, Hamblin R, Wass J, Karavitaki N. Cardiovascular health and mortality in Cushing’s disease. Pituitary. 2022 Jul 22;25(5):750-753. Epub 2022 Jul 22. doi: 10.1007/s11102-022-01258-4

Hamblin R, Vardon A, Akpalu J, Tampourlou M, Spiliotis I, Sbardella E et al. Risk of second brain tumour after radiotherapy for pituitary adenoma or craniopharyngioma: a retrospective, multicentre, cohort study of 3,679 patients with long-term imaging surveillance. The Lancet Diabetes and Endocrinology. 2022 Jul 19;10(8):581-588. Epub 2022 Jul 1. doi: 10.1016/S2213-8587(22)00160-7

Detomas M, Pivonello C, Pellegrini B, Landwehr L, Sbiera S, Pivonello R et al. MicroRNAs and long non-coding RNAs in adrenocortical carcinoma. Cells. 2022 Jul 18;11(14):2234. doi: 10.3390/cells11142234

Wang Z, Hazlehurst J, Subramanian A, Tahrani A, Hanif W, Thomas GN et al. Diabetic foot risk classification at the time of type 2 diabetes diagnosis and subsequent risk of mortality: a population-based cohort study. Frontiers in Endocrinology. 2022 Jul 11;13:888924. doi: 10.3389/fendo.2022.888924

Yang W, Abbott S, Borg C-M, Chesworth P, Graham Y, Logue J et al. Global variations in preoperative practices concerning patients seeking primary bariatric and metabolic surgery (PACT Study): a survey of 634 bariatric healthcare professionals. International Journal of Obesity. 2022 Jul;46(7):1341-1350. Epub 2022 Apr 11. doi: 10.1038/s41366-022-01119-x

GENEVA collaborators. Safety of Bariatric Surgery in ≥ 65-Year-Old Patients During the COVID-19 Pandemic. Obesity surgery. 2022 Jul;32(7):1-13. Epub 2022 May 5. doi: 10.1007/s11695-022-06067-z

Schneider E, Spetter MS, Martin E, Sapey E, Yip KP, Manolopoulos KN et al. The effect of intranasal insulin on appetite and mood in women with and without obesity: an experimental medicine study. International Journal of Obesity. 2022 Jul;46(7):1319-1327. Epub 2022 Apr 9. doi: 10.1038/s41366-022-01115-1

GENEVA collaborators. Effect of BMI on safety of bariatric surgery during the COVID-19 pandemic, procedure choice, and safety protocols - an analysis from the GENEVA Study. Obesity Research and Clinical Practice. 2022 Jun 20;16(3):249-253. Epub 2022 Jun 8. doi: 10.1016/j.orcp.2022.06.003

Shepherd LM, Schmidtke KA, Hazlehurst JM, Melson E, Dretzke J, Hawks N et al. Interventions for the prevention of adrenal crisis in adults with primary adrenal insufficiency: a systematic review. European Journal of Endocrinology . 2022 Jun 1;187(1):S1-S20. doi: 10.1530/EJE-21-1248

Gorvin CM. The importance of functionally characterizing calcium-sensing receptor variants in individuals with hypercalcemia. Journal of the Endocrine Society. 2022 Jun;6(6):1-2. bvac052. Epub 2022 Apr 4. doi: 10.1210/jendso/bvac052

Thaller M, Mytton J, Wakerley B, Mollan S, Sinclair A. Idiopathic intracranial hypertension: Evaluation of births and fertility through the Hospital Episode Statistics dataset. BJOG: An International Journal of Obstetrics & Gynaecology. 2022 May 27;129(12):1-9. Epub 2022 May 27. doi: 10.1111/1471-0528.17241

Mostafa SA, Mena SC, Antza C, Balanos G, Nirantharakumar K, Tahrani AA. Sleep behaviours and associated habits and the progression of pre-diabetes to type 2 diabetes mellitus in adults: A systematic review and meta-analysis. Diabetes and Vascular Disease Research. 2022 May 26;19(3):1-11. doi: 10.1177/14791641221088824

Idkowiak J, Smyth A, Mundy L, Wanaguru A, Gleeson H, Högler W. Breast satisfaction in adult women with Turner Syndrome: – an international survey employing the BREAST-Q questionnaire. Clinical Endocrinology. 2022 May 17;1-9. Epub 2022 May 17. doi: 10.1111/cen.14755

Hussain M, Egan H, Keyte R, Strachan R, Tahrani AA, Mantzios M. Exploring the association between self-compassion, mindfulness and mindful eating with eating behaviours amongst patients with obesity. Nutrition and health. 2022 May 11. Epub 2022 May 11. doi: 10.1177/02601060221094671

Deutschbein T, Reimondo G, Di Dalmazi G, Bancos I, Patrova J, Vassiliadi DA et al. Age-dependent and sex-dependent disparity in mortality in patients with adrenal incidentalomas and autonomous cortisol secretion: an international, retrospective, cohort study. The Lancet Diabetes and Endocrinology. 2022 May 6;10(7):499-508. Epub 2022 May 6. doi: 10.1016/S2213-8587(22)00100-0

Ronchi C, Altieri B. Special issue: Present and future of personalised medicine for endocrine cancers. Journal of Personalised Medicine . 2022 Apr 29;12(5):710. doi: 10.3390/jpm12050710

Ast J, Novak AN, Podewin T, Fine NHF, Jones B, Tomas A et al. Expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. JACS Au. 2022 Apr 25;2(4):1007-1017. Epub 2022 Apr 4. doi: 10.1021/jacsau.2c00130

Boguszewski M, Boguszewski CL, Chemaililly W, Cohen LE, Gebauer J, Higham CE et al. Safety of growth hormone replacement in survivors of cancer and intra-cranial and pituitary tumours: A consensus statement. European Journal of Endocrinology. 2022 Apr 21;186(6):P35-P52. doi: 10.1530/EJE-21-1186

Jouinot A, Lippert J, Sibony M, Violon F, Jeanpierre L, De Murat D et al. Transcriptome in paraffin samples for the diagnosis and prognosis of adrenocortical carcinoma. European Journal of Endocrinology. 2022 Apr 21;186(6):607-617. doi: 10.1530/EJE-21-1228

Brylski O, Shrestha P, House PJ, Gnutt P, Mueller JW, Ebbinghaus S. Disease-related protein variants of the highly conserved enzyme PAPSS2 show marginal stability and aggregation in cells. Frontiers in Molecular Bioscience. 2022 Apr 8;9:860387. doi: 10.3389/fmolb.2022.860387

Coulden A, Chortis V, Smyth T, Salahuddin S, Hanif W, Ghosh S. A quality improvement project reducing adverse events and improving adherence to guidelines surrounding VRIII usage. BMJ open quality. 2022 Apr 7;11(2):e001612. doi: 10.1136/bmjoq-2021-001612

Allen SL, Seabright AP, Quinlan JI, Dhaliwal A, Williams FR, Fine NHF et al. The effect of ex vivo human serum from liver disease patients on cellular protein synthesis and growth. Cells. 2022 Mar 24;11(7):1098. doi: 10.3390/cells11071098

Hazlehurst JM, Singh P, Bhogal G, Broughton S, Tahrani AA. How to manage weight loss in women with obesity and PCOS seeking fertility? Clinical Endocrinology. 2022 Mar 23;97(2):208-216. Epub 2022 Mar 23. doi: 10.1111/cen.14726

Hamblin R, Coulden A, Fountas A, Karavitaki N. The diagnosis and management of Cushing’s syndrome in pregnancy. Journal of Neuroendocrinology. 2022 Mar 14;34(8):e13118. Epub 2022 Mar 14. doi: 10.1111/jne.13118

Pauza AG, Thakka P, Tasic T, Felippe I, Bishop P, Greenwood MP et al. GLP1R attenuates sympathetic response to high glucose via carotid body inhibition. Circulation. 2022 Mar 4;130(5):694-707. Epub 2022 Feb 1. doi: 10.1161/CIRCRESAHA.121.319874

Prete A, Subramanian A, Bancos I, Chortis V, Tsagarakis S, Lang K et al. Cardiometabolic disease burden and steroid excretion in benign adrenal tumors: a cross-sectional multicenter study. Annals of internal medicine. 2022 Mar;175(3):325-334. Epub 2022 Jan 4. doi: 10.7326/M21-1737

Crasto W, Altaf Q-A, Selvaraj DR, Jack B, Patel V, Nawaz S et al. Frequency rhythmic electrical modulation system (FREMS) to alleviate painful diabetic peripheral neuropathy: a pilot, randomised controlled trial (The FREMSTOP study). Diabetic Medicine. 2022 Mar;39(3):e14710. Epub 2021 Oct 4. doi: 10.1111/dme.14710

Ajjan RA, Hensor EMA, Del Galdo F, Shams K, Abbas A, Fairclough RJ et al. Oral 11β-HSD1 inhibitor AZD4017 improves wound healing and skin integrity in adults with type 2 diabetes mellitus: a pilot randomized controlled trial. European Journal of Endocrinology . 2022 Feb 28;186(4):441-455. doi: 10.1530/EJE-21-1197

Kodsi R, Chimoriya R, Medveczky D, Grudzinskas K, Atlantis E, Tahrani AA et al. Clinical use of the Edmonton obesity staging system for the assessment of weight management outcomes in people with class 3 obesity. Nutrients. 2022 Feb 24;14(5):967. doi: 10.3390/nu14050967

Birke R, Ast J, Roosen DA, Lee J, Roßmann K, Huhn C et al. Sulfonated red and far-red rhodamines to visualize SNAP- and Halo-tagged cell surface proteins. Organic and Biomolecular Chemistry. 2022 Feb 21;20(30):5967-5980. Epub 2022 Feb 21. doi: 10.1039/D1OB02216D

Karsai M, Zuellig RA, Lehmann R, Cuozzo F, Nasteska D, Luca E et al. Lack of ZnT8 protects pancreatic islets from hypoxia- and cytokine induced cell death. Journal of Endocrinology. 2022 Feb 11;253(1):1-11. doi: 10.1530/JOE-21-0271

Gadelha M, Karavitaki N, Fudin J, Bettinger J, Raff H, Ben-Shlomo A. Opioids and pituitary function: expert opinion. Pituitary. 2022 Jan 23;25(1):52-63. Epub 2022 Jan 23. doi: 10.1007/s11102-021-01202-y

Moll JM, Hofland J, Teubel W, Ridder CMAD, Taylor A, Graeser R et al. Abiraterone switches castration‐resistant prostate cancer dependency from adrenal androgens towards androgen receptor variants and glucocorticoid receptor signalling. The Prostate. 2022 Jan 17;82(5):505-516. Epub 2022 Jan 17. doi: 10.1002/pros.24297

Almulhem M, Thayakaran R, Hanif S, Gooden T, Thomas GN, Hazlehurst J et al. Ramadan is not associated with increased infection risk in Pakistani and Bangladeshi populations: Findings from controlled interrupted time series analysis of UK primary care data. PLoS ONE. 2022 Jan 13;17(1):e0262530. doi: 10.1371/journal.pone.0262530

Hoang M, Jentz E, Janssen S, Nasteska D, Cuozzo F, Hodson D et al. Isoform-specific roles of prolyl hydroxylases in the regulation of pancreatic β-cell function. Endocrinology. 2022 Jan;163(1):1-17. bqab226. Epub 2021 Oct 28. doi: 10.1210/endocr/bqab226

Chowdhury M, Nevitt S, Eleftheriadou A, Kanagala P, Esa H, Cuthbertson DJ et al. Cardiac autonomic neuropathy and risk of cardiovascular disease and mortality in type 1 and type 2 diabetes: a meta-analysis. BMJ Open Diabetes Research and Care. 2021 Dec 30;9(2):e002480. doi: 10.1136/bmjdrc-2021-002480

Brylski O, Shrestha P, Gnutt P, Gnutt D, Mueller JW, Ebbinghaus S. Cellular ATP levels determine the stability of a nucleotide kinase. Frontiers in Molecular Bioscience. 2021 Dec 13;8:790304. doi: 10.3389/fmolb.2021.790304

Gokhale K, Mostafa SA, Wang J, Tahrani A, Sainsbury C, Toulis K et al. The clinical profile and associated mortality in people with and without diabetes with Coronavirus disease 2019 on admission to acute hospital services. Endocrinology, diabetes & metabolism. 2021 Dec 3;e00309. Epub 2021 Dec 3. doi: 10.1002/edm2.309

Kobuch S, Tsang F, Chimoriya R, Gossayn D, O'Brien S, Jamal J et al. Obstructive sleep apnoea and 12-month weight loss in adults with class 3 obesity attending a multidisciplinary weight management program. BMC Endocrine Disorders. 2021 Dec;21(1):227. Epub 2021 Nov 14. doi: 10.1186/s12902-021-00887-3

Mollan S, Homer V, Gates S, Brock K, Sinclair A. One eye or two: statistical considerations in ophthalmology with a focus on interventional clinical trials. Journal of Neuro-Ophthalmology. 2021 Dec;41(4):421-423. Epub 2021 Nov 18. doi: 10.1097/WNO.0000000000001446

Cantley NW, Lonnen K, Kyrou I, Tahrani AA, Kahal H. The association between overweight/obesity and double diabetes in adults with type 1 diabetes; a cross-sectional study. BMC Endocrine Disorders. 2021 Dec;21(1):187. Epub 2021 Sep 16. doi: 10.1186/s12902-021-00851-1

Costa A, Ai M, Nunn N, Culotta I, Hunter J, Boutagouga Boudjadja M et al. Anorectic and aversive effects of GLP-1 receptor agonism are mediated by brainstem cholecystokinin neurons, and modulated by GIP receptor activation. Molecular metabolism. 2021 Nov 26;55:101407. Epub 2021 Nov 26. doi: 10.1016/j.molmet.2021.101407

Price ML, Ley CD, Gorvin CM. The emerging role of heterodimerisation and interacting proteins in ghrelin receptor function. Journal of Endocrinology. 2021 Nov 24;252(1):R23-R39. doi: 10.1530/JOE-21-0206

Flint SW, Brown A, Sanders G, Tahrani AA. Exploring the awareness, attitudes, and actions (AAA) of UK adults at high risk of severe illness from COVID-19. PLoS ONE. 2021 Nov 11;16(11):e0259376. doi: 10.1371/journal.pone.0259376

Read M, Brookes K, Thornton C, Nieto H, Zha L, Fletcher A et al. An emerging role for proteostasis modulators targeting NIS activity to enhance radioiodide therapy in thyroid cancer. Endocrine Abstracts. 2021 Nov 8;77:OC2.2. doi: 10.1530/endoabs.77.OC2.2

Lippert J, Fassnacht M, Ronchi C. The role of molecular profiling in adrenocortical carcinoma. Clinical Endocrinology. 2021 Nov 8. Epub 2021 Nov 8. doi: 10.1111/cen.14629

Singh P, Adderley N, Hazlehurst J, Price M, Tahrani A, Nirantharakumar K et al. Prognostic models for predicting remission of diabetes following bariatric surgery: a systematic review and meta-analysis. Diabetes Care. 2021 Nov;44(11):2626-2641. Epub 2021 Oct 20. doi: 10.2337/dc21-0166

Hamblin R, Tsermoulas G, Karavitaki N. Craniopharyngiomas. La Presse Medicale. 2021 Oct 22;50(4):104078. Epub 2021 Oct 22. doi: 10.1016/j.lpm.2021.104078

Fleseriu M, Karavitaki N. Consensus on diagnosis and management of Cushing’s disease: a guideline update. The Lancet Diabetes and Endocrinology. 2021 Oct 20. Epub 2021 Oct 20. doi: 10.1016/S2213-8587(21)00235-7

Sun M, Mueller JW, Gilligan LC, Taylor AE, Shaheen F, Noczyńska A et al. The broad phenotypic spectrum of 17α-hydroxylase/17,20-lyase (CYP17A1) deficiency: a case series. European Journal of Endocrinology . 2021 Oct 11;185(5):729-741. doi: 10.1530/EJE-21-0152

Torlinska B, Hazlehurst JM, Nirantharakumar K, Thomas GN, Priestley JR, Finnikin SJ et al. wEight chanGes, caRdio-mEtabolic risks and morTality in patients with hyperthyroidism (EGRET): a protocol for a CPRD-HES linked cohort study. BMJ open. 2021 Oct 1;11(10):e055219. doi: 10.1136/bmjopen-2021-055219

GENEVA collaborators. 30-Day Morbidity and Mortality of Bariatric Surgery During the COVID-19 Pandemic: a Multinational Cohort Study of 7704 Patients from 42 Countries. Obesity surgery. 2021 Oct;31(10):4272-4288. Epub 2021 Jul 30. doi: 10.1007/s11695-021-05493-9

Lucey M, Ashik T, Marzook A, Wang Y, Goulding J, Oishi A et al. Acylation of the incretin peptide exendin-4 directly impacts glucagon-like peptide-1 receptor signaling and trafficking. Molecular Pharmacology. 2021 Oct;100(4):319-334. Epub 2021 Jul 27. doi: 10.1124/molpharm.121.000270

Read M, Brookes K, Thornton C, Fletcher A, Nieto H, Alshahrani M et al. Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter. Cell Chemical Biology. 2021 Sep 13;2021:1-23. doi: 10.1016/j.chembiol.2021.07.016

Grech O, Clouter A, Mitchell J, Alimajstorovic Z, Ottridge R, Yiangou A et al. Cognitive performance in idiopathic intracranial hypertension and relevance of intracranial pressure. Brain Communications. 2021 Sep 2;3(3):fcab202. Epub 2021 Sep 2. doi: 10.1093/braincomms/fcab202

Pickford P, Lucey MA, Rujan R-M, McGlone ER, Bitsi S, Ashford F et al. Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist. Molecular metabolism. 2021 Sep;51:101242. Epub 2021 Apr 30. doi: 10.1016/j.molmet.2021.101242

Gorvin CM. GPCRs and Endocrinology. In Reference Module in Biomedical Sciences. Elsevier. 2021 doi: https://doi.org/10.1016/B978-0-12-820472-6.00020-7

Read, M., Brookes, K., Thornton, C., Fletcher, A., Nieto, H., Alshahrani, M., Khan, R., Borges de Souza, P., Zha, L., Webster, J., Alderwick, L., Campbell, M., Boelaert, K., Smith, V., & McCabe, C. (2021). Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter. Cell Chemical Biology, 2021, 1-23. https://doi.org/10.1016/j.chembiol.2021.07.016

Grech, O., Clouter, A., Mitchell, J., Alimajstorovic, Z., Ottridge, R., Yiangou, A., Roque, M., Tahrani, A., Nicholls, M., Taylor, A., Shaheen, F., Arlt, W., Lavery, G., Shapiro, K., Mollan, S., & Sinclair, A. (2021). Cognitive performance in idiopathic intracranial hypertension and relevance of intracranial pressure. Brain Communications, 3(3), [fcab202]. https://doi.org/10.1093/braincomms/fcab202

Pickford, P., Lucey, M. A., Rujan, R-M., McGlone, E. R., Bitsi, S., Ashford, F., Corrêa, I. R., Hodson, D., Tomas, A., Deganutti, G., Reynolds, C. A., Owen, B., Tan, T. M., Minnion, J., Jones, B., & Bloom, S. R. (2021). Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist. Molecular metabolism, 51, [101242]. https://doi.org/10.1016/j.molmet.2021.101242

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Singh, P., Adderley, N., Hazlehurst, J., Price, M., Tahrani, A., Nirantharakumar, K., & Bellary, S. (Accepted/In press). Prognostic models for predicting remission of diabetes following bariatric surgery: a systematic review and meta-analysis. Diabetes Care.

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Lucey, M., Ashik, T., Marzook, A., Wang, Y., Goulding, J., Oishi, A., Broichhagen, J., Hodson, D. J., Minnion, J., Elani, Y., Jockers, R., Briddon, S. J., Bloom, S. R., Tomas, A., & Jones, B. (Accepted/In press). Acylation of the incretin peptide exendin-4 directly impacts GLP-1 receptor signalling and trafficking. Molecular Pharmacology. https://doi.org/10.1124/molpharm.121.000270

Singhal, R., Wiggins, T., Super, J., Alqahtani, A., Nadler, E. P., Ludwig, C., Tahrani, A., & Mahawar, K. (2021). 30-Day morbidity and mortality of bariatric metabolic surgery in adolescence during the COVID-19 pandemic - The GENEVA study. Pediatric Obesity, [e12832]. https://doi.org/10.1111/ijpo.12832

Olaniru, O., Cheng, J., Ast, J., Arvaniti, A., Atanes, P., Huang, GC., King, A., Jones, P., Broichhagen, J., Hodson, D., & Persaud, S. J. (2021). SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells. Molecular metabolism, 53, [101285]. https://doi.org/10.1016/j.molmet.2021.101285

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Eigenbrodt, A., Ashina, H., Khan, S., Diener, H-C., Mitsikostas, D., Sinclair, A., Pozo-Rosich, P., Martelletti, P., Ducros, A., Lanteri-Minet, M., Braschinsky, M., Sanchez Del Rio, M., Daniel, O., Ozge, A., Mammadbayli, A., Arons, M., Skorobogatykh, K., Romanenko, V., Terwindt, G., ... Ashina, M. (2021). Diagnosis and management of migraine in ten steps: consensus statement. Nature Reviews Neurology. https://doi.org/10.1038/s41582-021-00509-5

Mollan, S., Grech, O., & Sinclair, A. (2021). Headache attributed to idiopathic intracranial hypertension (IIH) and persistent post-IIH headache: a narrative review. Headache. https://doi.org/10.1111/head.14125

Mollan, S., Mitchell, J., Ottridge, R., Aguiar, M., Alimajstorovic, Z., Cartwright, D., Grech, O., Lavery, G., Westgate, C., Vijay, V., Scotton, W., Wakerley, B., Matthews, T., Ansons, A., Hickman, S., Benzimra, J., Rick, C., Singhal, R., Tahrani, A., ... Sinclair, A. (2021). Effectiveness of Bariatric Surgery vs Community Weight Management Intervention for the Treatment of Idiopathic Intracranial Hypertension: A Randomized Clinical Trial. JAMA Neurology, 78(6), 678-686. https://doi.org/10.1001/jamaneurol.2021.0659

Read, M., Brookes, K., Thornton, C., Nieto, H., Fletcher, A., Zha, L., Alderwick, L., Boelaert, K., Smith, V., & McCabe, C. (2021). Targeting non-canonical pathways as a strategy to modulate radioiodide uptake in thyroid cancer. Abstract from 27TH CONGRESS OF THE EUROPEAN ASSOCIATION FOR CANCER RESEARCH.

Mollan, S., & Sinclair, A. (2021). Outcomes measures in idiopathic intracranial hypertension. Expert Review of Neurotherapeutics. https://doi.org/10.1080/14737175.2021.1931127

Mollan, S., Chong, Y. J., Grech, O., Sinclair, A., & Wakerley, B. (2021). Current perspectives on idiopathic intracranial hypertension without papilloedema. Life, 11, [472]. https://doi.org/10.3390/life11060472

Westgate, C., Botfield, H., Alimajstorovic, Z., Yiangou, A., Walsh, M., Smith, G., Singhal, R., Mitchell, J., Grech, O., Markey, K., Hebenstreit, D., Tennant, D., Tomlinson, J., Mollan, S., Ludwig, C., Akerman, I., Lavery, G., & Sinclair, A. (2021). Systemic and adipocyte transcriptional and metabolic dysregulation in idiopathic intracranial hypertension. JCI Insight, 6(10), [e145346]. https://doi.org/10.1172/jci.insight.145346

Burden and Attitude to Resistant and Refractory (BARR) Study Group, Sacco, S., Lampl, C., Maassen Van Den Brink, A., Caponnetto, V., Braschinsky, M., Ducros, A., Little, P., Pozo-Rosich, P., Reuter, U., Ruiz De La Torre, E., Sanchez Del Rio, M., Sinclair, A., Martelletti, P., & Katsarava, Z. (2021). Burden and attitude to resistant and refractory migraine: a survey from the European Headache Federation with the endorsement of the European Migraine & Headache Alliance. The Journal of Headache and Pain, 22, [39]. https://doi.org/10.1186/s10194-021-01252-4

Gorvin, C. M. (2021). Genetic causes of neonatal and infantile hypercalcaemia. Pediatric Nephrology. https://doi.org/10.1007/s00467-021-05082-z

Foster, P. (2021). Steroid sulphatase and its inhibitors: past, present and future. Molecules, 26(10), [2852]. https://doi.org/10.3390/molecules26102852

Mollan, S., Mytton, J., Tsermoulas, G., & Sinclair, A. (2021). Idiopathic intracranial hypertension: evaluation of admissions and emergency readmissions through the hospital episode statistic dataset between 2002–2020. Life, 11(5), [417]. https://doi.org/10.3390/life11050417

Shad, B. J., Thompson, J. L., Mckendry, J., Holwerda, A. M., Elhassan, Y. S., Breen, L., van Loon, L. J. C., & Wallis, G. A. (2021). Daily myofibrillar protein synthesis rates in response to low- and high-frequency resistance exercise training in healthy, young men. International journal of sport nutrition and exercise metabolism, 31(3), 209–216. https://doi.org/10.1123/ijsnem.2020-0274

Grech, O., Mollan, S., Wakerley, B., Fulton, D., Lavery, G., & Sinclair, A. (2021). The role of metabolism in migraine pathophysiology and susceptibility. Life: Physiology and Pathology, 11(5), [415]. https://doi.org/10.3390/life11050415

Aguiar, M., Frew, E., Mollan, S., Mitchell, J., Ottridge, R., Alimajstorovic, Z., Yiangou, A., Singhal, R., Tahrani, A., & Sinclair, A. (2021). The health economic evaluation of bariatric surgery versus a community weight management intervention analysis from the idiopathic intracranial hypertension weight trial (IIH:WT). Life, 11(5), [409]. https://doi.org/10.3390/life11050409

Akerman, I., Maestro, M. A., De Franco, E., Grau, V., Flanagan, S., Garcia-Hurtado, J., Mittler, G., Ravassard, P., Piemonti, L., Ellard, S., Hattersley, A. T., & Ferrer, J. (2021). Neonatal diabetes mutations disrupt a chromatin pioneering function that activates the human insulin gene. Cell Reports, 35(2), [108981]. https://doi.org/10.1016/j.celrep.2021.108981

Powell, L., & Foster, P. (2021). Protein disulphide isomerase inhibition as a potential cancer therapeutic strategy. Cancer Medicine, 10(8), 2812-2825. https://doi.org/10.1002/cam4.3836

Antza, C., Ottridge, R., Patel, S., Slinn, G., Tearne, S., Nicholls, M., Cooper, B., Ali, A., & Tahrani, A. (2021). The impact of sleep disorders on microvascular complications in patients with type 2 diabetes (SLEEP T2D): the protocol of a cohort study and feasibility randomised control trial. Pilot and Feasibility Studies, 7(1), [80]. https://doi.org/10.1186/s40814-021-00817-z

Mueller, J. W., Vogg, N., Lightning, T. A., Weigand, I., Ronchi, C., Foster, P., & Kroiss, M. (2021). Steroid sulfation in adrenal tumors. Journal of Clinical Endocrinology and Metabolism, 2021(00), [dgab182]. https://doi.org/10.1210/clinem/dgab182

Hakami, O., Ahmed, S. K., & Karavitaki, N. (2021). Epidemiology and mortality of Cushing’s syndrome. Best practice & research. Clinical endocrinology & metabolism, [101521]. https://doi.org/10.1016/j.beem.2021.101521

Lightning, T. A., Gesteira, T. F., & Mueller, J. W. (2021). Steroid disulfates - Sulfation double trouble Molecular and Cellular Endocrinology. Molecular and Cellular Endocrinology, 524, [111161]. https://doi.org/10.1016/j.mce.2021.111161

Viloria, K., Hewison, M., & Hodson, D. (2021). Vitamin D-binding protein/GC-globulin: a novel regulator of alpha cell function and glucagon secretion. Journal of Physiology. https://doi.org/10.1113/JP280890

Read, M., Brookes, K., Thornton, C., Fletcher, A., Nieto, H., Alshahrani, M., Khan, R., Borges de Souza, P., Zha, L., Webster, J., Alderwick, L., Campbell, M., Boelaert, K., Smith, V., & McCabe, C. (2021). Targeting non-canonical pathways as a strategy to modulate the NIS symporter. SSRN. https://doi.org/10.2139/ssrn.3797274

Barnard, L., Schiffer, L., Du-Toit, R. L., Tamblyn, J., Chen, S., Africander, D., Arlt, W., Foster, P., & Storbeck, K-H. (2021). 11-oxygenated estrogens are a novel class of human estrogens but do not contribute to the circulating estrogen pool. Endocrinology, 162(3), [bqaa231]. https://doi.org/10.1210/endocr/bqaa231

Reincke, M., Albani, A., Assie, G., Bancos, I., Brue, T., Buchfelder, M., Chabre, O., Ceccato, F., Daniele, A., Detomas, M., Di Dalmazi, G., Elenkova, A., Findling, J., Grossman, A., Gomez-Sanchez, C., Heaney, A., Honegger, J., Karavitaki, N., Lacroix, A., ... Ritzel, K. (2021). Corticotroph tumor progression after bilateral adrenalectomy (Nelson’s syndrome): systematic review and expert consensus recommendations. European Journal of Endocrinology, 184(3), P1–P16. https://doi.org/10.1530/EJE-20-1088

Riley, J., Antza, C., Kempegowda, P., Subramanian, A., Chandan, J. S., Gokhale, K., Thomas, N., Sainsbury, C., Tahrani, A. A., & Nirantharakumar, K. (2021). Social deprivation and incident diabetes-related foot disease in patients with type 2 diabetes: a population-based cohort study. Diabetes Care, 44(3), 731-739. https://doi.org/10.2337/dc20-1027

Aojula, N., Ready, A., Gittoes, N., & Hassan-Smith, Z. (2021). Management of Parathyroid Disease during the COVID-19 Pandemic. Journal of Clinical Medicine, 10(5), [920]. https://doi.org/10.3390/jcm10050920

Pezhman, L., Tahrani, A., & Chimen, M. (2021). Dysregulation of Leukocyte Trafficking in Type 2 Diabetes: Mechanisms and Potential Therapeutic Avenues. Frontiers in cell and developmental biology, 9, [624184]. https://doi.org/10.3389/fcell.2021.624184

Weigand, I., Ronchi, C., Vanselow, J. T., Bathon, K., Lenz, K., Herterich, S., Schlosser, A., Kroiss, M., Fassnacht, M., Calebiro, D., & Sbiera, S. (2021). PKA Cα subunit mutation triggers caspase-dependent RIIβ subunit degradation via Ser¹¹⁴ phosphorylation. Science Advances, 7(8), [eabd4176]. https://doi.org/10.1126/sciadv.abd4176

Smeuninx, B., Elhassan, Y. S., Manolopoulos, K. N., Sapey, E., Rushton, A. B., Edwards, S. J., Morgan, P. T., Philp, A., Brook, M. S., Gharahdaghi, N., Smith, K., Atherton, P. J., & Breen, L. (2021). The effect of short-term exercise prehabilitation on skeletal muscle protein synthesis and atrophy during bed rest in older men. Journal of cachexia, sarcopenia and muscle, 12(1), 52-69. https://doi.org/10.1002/jcsm.12661

Wang, J., Cooper, J., Gokhale, K., Acosta-Mena , D., Dhalla , S., Byne , N., Chandan, J. S., Anand, A., Okoth, K., Subramanian, A., Bangash, M., Jackson, T., Zemedikun, D., Taverner, T., Hanif, W., Ghosh, S., Narendran, P., Toulis, K., Tahrani, A., ... Nirantharakumar, K. (2021). Association of metformin with susceptibility to COVID-19 in people with type 2 diabetes. Journal of Clinical Endocrinology and Metabolism, [dgab067]. https://doi.org/10.1210/clinem/dgab067

Gorvin, C. M. (2021). Calcium-sensing receptor signaling - how human disease informs biology. Current Opinion in Endocrine and Metabolic Research, 16, 10-18. https://doi.org/10.1016/j.coemr.2020.06.007

Fenton, C., Martin, C., Jones, R., Croft, A., Campos, J., Naylor, A., Taylor, A., Chimen, M., Cooper, M., Lavery, G., Raza, K., & Hardy, R. (2021). Local steroid activation is a critical mediator of the anti-inflammatory actions of therapeutic glucocorticoids. Annals of the Rheumatic Diseases, 80(2), 250-260. https://doi.org/10.1136/annrheumdis-2020-218493

Subramanian, A., Idkowiak, J., Toulis, K., Thangaratinam, S., Arlt, W., & Nirantharakumar, K. (2021). Pubertal timing in boys and girls born to mothers with gestational diabetes mellitus: a systematic review. European Journal of Endocrinology, 184(1), 51–64. https://doi.org/10.1530/EJE-20-0296

Gorvin, C. M. (2021). GPCRs and Endocrinology. In Reference Module in Biomedical Sciences Elsevier. https://doi.org/10.1016/B978-0-12-820472-6.00020-7

Nasteska, D., Fine, N., Ashford, F., Cuozzo, F., Viloria, K., Smith, G., Dahir, A., Dawson, P. W. J., Lai, Y-C., Bastidas-Ponce, A., Bakhti, M., Rutter, G., Fiancette, R., Nano, R., Piemonti, L., Lickert, H., Zhou, Q., Akerman, I., & Hodson, D. (2021). PDX1^LOW MAFA^LOW β-cells contribute to islet function and insulin release. Nature Communications, 12(1), [674]. https://doi.org/10.1038/s41467-020-20632-z

Yiangou, A., Mitchell, J., Fisher, C., Edwards, J., Vijay, V., Alimajstorovic, Z., Grech, O., Lavery, G., Mollan, S., & Sinclair, A. (2021). Erenumab for headaches in idiopathic intracranial hypertension: a prospective open-label evaluation. Headache, 61(1), 157-169. https://doi.org/0.1111/head.14026

Shahzad, A. (2021). Dielectric characterization of ex vivo ovine and human adrenal glands for microwave thermal ablation applications. IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology, 2021(00), 1-9. https://doi.org/10.1109/JERM.2021.3052108

Hardy, R., Botfield, H., Markey, K., Mitchell, J., Alimajstorovic, Z., Westgate, C., Sagmeister, M., Fairclough, R., Ottridge, R., Yiangou, A., Storbeck, K-H., Taylor, A., Gilligan, L., Arlt, W., Stewart, P., Tomlinson, J., Mollan, S., Lavery, G., & Sinclair, A. (2021). 11βHSD1 inhibition with AZD4017 improves lipid profiles and lean muscle mass in Idiopathic intracranial hypertension. Journal of Clinical Endocrinology and Metabolism, 106(1), 174-187. https://doi.org/10.1210/clinem/dgaa766

Singhal, R., Tahrani, A., Ludwig, C., Mahawar, K., & GENEVA collaborators (2021). Global 30-day outcomes after bariatric surgery during the COVID-19 pandemic (GENEVA): an international cohort study. The Lancet Diabetes and Endocrinology, 9(1), [7-9]. https://doi.org/10.1016/S2213-8587(20)30375-2

Singh, P., Adderley, N., Subramanian, A., Gokhale, K., Singhal, R., Toulis, K., Bellary, S., Nirantharakumar, K., & Tahrani, A. (2021). The impact of bariatric surgery on incident microvascular complications in patients with type 2 diabetes: a matched controlled population-based retrospective cohort study. Diabetes Care, 44(1), 116-124. https://doi.org/10.2337/dc20-0571

Lempesis, I. G., Goossens, G. H., & Manolopoulos, K. N. (2021). Measurement of human abdominal and femoral intravascular adipose tissue blood flow using percutaneous Doppler ultrasound. Adipocyte, 10(1), 119-123. https://doi.org/10.1080/21623945.2021.1888471

Abbott, S., Parretti, H., Hazlehurst, J., & Tahrani, A. (2020). Socio-demographic predictors of uptake of a virtual group weight management program during the COVID-19 pandemic. Journal of Human Nutrition and Dietetics. https://doi.org/10.1111/jhn.12850

McLean, B., Wong, C. K., Campbell, J., Hodson, D., Trapp, S., & Drucker, D. (2020). Revisiting the complexity of GLP-1 action-from sites of synthesis to receptor activation. Endocrine Reviews. https://doi.org/10.1210/endrev/bnaa032

Parretti, H., Subramanian, A., Adderley, N., Abbott, S., Tahrani, A., & Nirantharakumar, K. (2020). Post-bariatric surgery nutritional follow-up in primary care: a population-based cohort study. British Journal of General Practice , 2020(00), 1-23. https://doi.org/10.3399/bjgp20X714161

Hazlehurst, J., Logue, J., Parretti, H., Abbott, S., Brown, A., Pournaras, D., & Tahrani, A. (2020). Developing integrated clinical pathways for the management of clinically severe adult obesity: A critique of NHS England policy. Current Obesity Reports, 9, 530–543. https://doi.org/10.1007/s13679-020-00416-8

Vusirikala, A., Thomas, T., Bhala, N., Tahrani, A. A., Thomas, G. N., & Nirantharakumar, K. (2020). Impact of obesity and metabolic health status in the development of non-alcoholic fatty liver disease (NAFLD): a United Kingdom population-based cohort study using the health improvement network (THIN). BMC Endocrine Disorders, 20(1), [96]. https://doi.org/10.1186/s12902-020-00582-9

Ast, J., Arvaniti, A., Fine, N. H. F., Nasteska, D., Ashford, F. B., Stamataki, Z., Koszegi, Z., Bacon, A., Jones, B. J., Lucey, M. A., Sasaki, S., Brierley, D. I., Hastoy, B., Tomas, A., D’agostino, G., Reimann, F., Lynn, F. C., Reissaus, C. A., Linnemann, A. K., ... Hodson, D. J. (2020). Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. Nature Communications, 11(1), [467 ]. https://doi.org/10.1038/s41467-020-14309-w

Webster, J., Kempen, L., Hardy, R., & Langen, R. (2020). Inflammation and skeletal muscle wasting during cachexia. Frontiers in Physiology, 2020, [597675]. https://doi.org/10.3389/fphys.2020.597675

Mollan, S., Grech, O., Alimajstorovic, Z., Wakerley, B., & Sinclair, A. (2020). New horizons for Idiopathic intracranial hypertension. British Medical Bulletin, [ldaa034]. https://doi.org/10.1093/bmb/ldaa034

Fang, Z., Chen, S., Manchanda, Y., Bitsi, S., Pickford, P., David, A., Shchepinova, M., Corrêa, I. R., Hodson, D., Broichhagen, J., Tate, E., Reimann, F., Salem, V., Rutter, G., Tan, T. M., Bloom, S. R., Tomas, A., & Jones, B. (2020). Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells. International Journal of Molecular Sciences, 21(21), [8404]. https://doi.org/10.3390/ijms21218404

Graham, Y., Mahawar, K., Riera, M., Islam, O., Bhasker, A., Wilson, M., Tahrani, A., Moize, V., Leal, A., & Ha, C. (2020). Emotional resilience and bariatric surgical teams: a priority in the pandemic. Obesity surgery. https://doi.org/10.1007/s11695-020-05083-1, https://doi.org/10.1007/s11695-020-05083-1

Vijay, V., Mollan, S., Mitchell, J., Bilton, E., Alimajstorovic, Z., Markey, K., Fong, A., Walker, J., Lyons, H., Yiangou, A., Tsermoulas, G., Brock, K., & Sinclair, A. (2020). Using Optical Coherence Tomography as a Surrogate of Measurements of Intracranial Pressure in Idiopathic Intracranial Hypertension. JAMA Ophthalmology. https://doi.org/10.1001/jamaophthalmol.2020.4242

Chifu, I., Heinze, B., Fuss, C., Lang, K., Kroiss, M., Kircher, S., Ronchi, C., Altieri, B., Schirbel, A., Fassnacht, M., & Hahner, S. (Accepted/In press). Impact of the Chemokine Receptors CXCR4 and CXCR7 on Clinical Outcome in Adrenocortical Carcinoma. Frontiers in Endocrinology.

Okoth, K., Chandan, J., Marshall, T., Thangaratinam, S., Thomas, G. N., Nirantharakumar, K., & Adderley, N. (2020). The association between the reproductive health of young women and cardiovascular disease in later life: An umbrella review. BMJ, 371, 1-21. [m3502]. https://doi.org/10.1136/bmj.m3502

Majidi, F., Martino, S., Kondakci, M., Antke, C., Haase, M., Chortis, V., Arlt, W., Ronchi, C., Fassnacht, M., Laurent, C., Petit, J-M., Casasnovas, O., Habra, M., Kanji, A., Salvatori, R., Ho, A. T. N., Spyroglou, A., Beuschlein, F., Villa, D., ... Gattermann, N. (2020). Clinical spectrum of primary adrenal lymphoma: results of a multicenter cohort study. European Journal of Endocrinology, 183(4), 453–462. https://doi.org/10.1530/EJE-19-0506

Carrat, G. R., Haythorne, E., Tomas, A., Haataja, L., Müller, A., Arvan, P., Piunti, A., Cheng, K., Huang, M., Pullen, T. J., Georgiadou, E., Stylianides, T., Amirruddin, N. S., Salem, V., Distaso, W., Cakebread, A., Heesom, K. J., Lewis, P. A., Hodson, D. J., ... Rutter, G. A. (2020). The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis. Molecular metabolism, 40, [101015]. https://doi.org/10.1016/j.molmet.2020.101015

Yiangou, A., Mitchell, J., Vijay, V., Grech, O., Bilton, E., Lavery, G., Fisher, C., Edwards, J., Mollan, S., & Sinclair, A. (2020). Calcitonin gene related peptide monoclonal antibody treats headache in patients with active idiopathic intracranial hypertension. The Journal of Headache and Pain, 21(1), [116 ]. https://doi.org/10.1186/s10194-020-01182-7

Bellary, S., Tahrani, A., & Barnett, A. H. (2020). Improving management of diabetic kidney disease: will GLP-1 receptor agonists have a role? The Lancet Diabetes and Endocrinology. https://doi.org/10.1016/S2213-8587(20)30301-6

Virdee, J., Larcombe, S., Vijay, V., Sinclair, A., Dayan, M., & Mollan, S. (2020). Reviewing the recent developments in idiopathic intracranial hypertension. Ophthalmology and Therapy. https://doi.org/10.1007/s40123-020-00296-0

Fountas, A., & Karavitaki, N. (2020). Nelson’s syndrome: an update. Endocrinology and Metabolism Clinics of North America, 49(3), 413-432. https://doi.org/10.1016/j.ecl.2020.05.004

ENSAT EURINE-ACT Investigators (2020). Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study. The Lancet Diabetes and Endocrinology, 8(9), 773-781. https://doi.org/10.1016/S2213-8587(20)30218-7

Gittoes, N., Criseno, S., Appelman-Dijkstra, N., Bollerslev, J., Canalis, E., Rejnmark, L., & Hassan-Smith, Z. (2020). Endocrinology in the time of COVID-19: Management of calcium metabolic disorders and osteoporosis. European Journal of Endocrinology, 183(2), G57-G65. https://doi.org/10.1530/EJE-20-0385

Adderley, N., Subramanian, A., Toulis, K., Gokhale, K., Taverner, T., Hanif, W., Haroon, S., Thomas, G. N., Sainsbury, C., Tahrani, A., & Nirantharakumar, K. (2020). Obstructive sleep apnea, a risk factor for cardiovascular and microvascular disease in patients with type 2 diabetes: findings from a population-based cohort study. Diabetes Care, 43(8), 1868-1877. https://doi.org/10.2337/dc19-2116

Harrison, S. R., Jutley, G., Li, D., Sahbudin, I., Filer, A., Hewison, M., & Raza, K. (2020). Vitamin D and early rheumatoid arthritis. BMC Rheumatology, 4, [38]. https://doi.org/10.1186/s41927-020-00134-7

Grech, O., Mollan, S., Wakerley, B., Alimajstorovic, Z., Lavery, G., & Sinclair, A. (2020). Emerging themes in Idiopathic Intracranial Hypertension. Journal of Neurology. https://doi.org/10.1007/s00415-020-10090-4

Read, M. L., Brookes, K., Thornton, C. E. M., Fletcher, A., Alshahrani, M., Khan, R., Nieto, H. R., Souza, P. B. D., Webster, J. R. M., Alderwick, L. J., Boelaert, K., Smith, V. E., & McCabe, C. J. (2020, Jul 22). New mechanisms of radioiodide uptake revealed via a novel high throughput drug screening approach in thyroid cancer. https://doi.org/10.1101/2020.07.21.213967

Ntali, G., Hakami, O., Wattegama, M., Ahmed, S., & Karavitaki, N. (2020). Mortality of patients with Cushing’s disease. Experimental and Clinical Endocrinology and Diabetes. https://doi.org/10.1055/a-1197-6380

Poc, P., Gutzeit, V., Ast, J., Lee, J., Jones, B. J., D’este, E., Mathes, B., Lehmann, M., Hodson, D., Levitz, J., & Broichhagen, J. (2020). Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates. Chemical Science, 1-13. https://doi.org/10.1039/d0sc02794d

Abbott, S., Lawson, J., Singhal, R., Parretti, H., & Tahrani, A. (2020). Weight loss during medical weight management does not predict weight loss after bariatric surgery: a retrospective cohort study. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery.

Jouinot, A., Lippert, J., Fassnacht, M., De La Villeon, B., Septier, A., Neou, M., Perlemoine, K., Appenzeller, S., Sibony, M., Gaujoux, S., Dousset, B., Libe, R., Groussin, L., Ronchi, C., Assie', G., & Bertherat, J. (Accepted/In press). Intratumor heterogeneity of prognostic DNA-based molecular markers in adrenocortical carcinoma. Endocrine Connections. https://doi.org/10.1530/EC-20-0228

Prete, A., Taylor, A., Bancos, I., Smith, D., Foster, M., Kohler, S., Fazal-Sanderson, V., Komninos, J., O'Neil, D., Vas, D., Mowatt, C., Mihai, R., Fallowfield, J., Annane, D., Lord, J., Keevil, B., Wass, J., Karavitaki, N., & Arlt, W. (2020). Prevention of adrenal crisis: cortisol responses to major stress compared to stress dose hydrocortisone delivery. Journal of Clinical Endocrinology and Metabolism, 105(7), 2262–2274. https://doi.org/10.1210/clinem/dgaa133

Flint, S. W., & Tahrani, A. (2020). COVID-19 and obesity-lack of clarity, guidance, and implications for care. The Lancet Diabetes and Endocrinology, 8(6), 474-475. https://doi.org/10.1016/S2213-8587(20)30156-X

Sacco, S., Braschinsky, M., Ducros, A., Lampl, C., Little, P., Maassen Van Den Brink, A., Pozo-Rosich, P., Reuter, U., Ruiz De La Torre, E., Sanchez Del Rio, M., Sinclair, A., Katsarava, Z., & Martelletti, P. (2020). European headache federation consensus on the definition of resistant and refractory migraine : developed with the endorsement of the European Migraine & Headache Alliance (EMHA). The Journal of Headache and Pain, 21, [76]. https://doi.org/10.1186/s10194-020-01130-5

Viloria, K. M., Nasteska, D., Briant, L. J. B., Heising, S., Larner, D., Fine, N., Ashford, F., Da Silva Xavier, G., Jimenez-Gonzalez, M., Hasib, A., Cuozzo, F., Manning Fox, J., MacDonald, P., Akerman, I., Lavery, G., Flaxman, C., Morgan, N., Richardson, S., Hewison, M., & Hodson, D. (2020). Vitamin-D-binding protein contributes to the maintenance of α cell function and glucagon secretion. Cell Reports, 31(11), [107761]. https://doi.org/10.1016/j.celrep.2020.107761

Lithgow, K., Siqueira, I., Senthil, L., Chew, H., Chavda, S., Ayuk, J., Toogood, A., Gittoes, N., Matthews, T., Batra, R., Meade, S., Sanghera, P., Khan, N., Ahmed, S., Paluzzi, A., Tsermoulas, G., & Karavitaki, N. (2020). Pituitary metastases: presentation and outcomes from a pituitary center over the last decade. Pituitary, 23(3), 258–265. https://doi.org/10.1007/s11102-020-01034-2

Kemkem, Y., Nasteska, D., De Bray, A., Bargi-Souza, P., Peliciari-Garcia, R., Guillou, A., Mollard, P., Hodson, D., & Schaeffer, M. (2020). Maternal hypothyroidism in mice influences glucose metabolism in adult offspring. Diabetologia. https://doi.org/10.1007/s00125-020-05172-x

Weigand, I., Altieri, B., Lacombe, A., Basile, V., Kircher, S., Landwehr, L-S., Schreiner, J., Zerbini, M., Ronchi, C., Megerle, F., Berruti, A., Canu, L., Volante, M., Paiva, I., Della Casa, S., Sbiera, S., Fassnacht, M., Fragoso, M., Terzolo, M., & Kroiss, M. (2020). Expression of SOAT1 in adrenocortical carcinoma and response to mitotane monotherapy: an ENSAT multicenter study. The Journal of clinical endocrinology and metabolism. https://doi.org/10.1210/clinem/dgaa293

Dekkers, O., Karavitaki, N., & Pereira, A. (2020). The epidemiology of aggresssive pituitary tumors (and its challenges). Reviews in endocrine & metabolic disorders. https://doi.org/10.1007/s11154-020-09556-7

Fleseriu, M., Karavitaki, N., & Dekkers, O. (2020). Endocrinology in the time of COVID-19: management of pituitary tumours. European Journal of Endocrinology. https://doi.org/10.1530/EJE-20-0473

Hodson, D., & Rorsman, P. (2020). A variation on the theme: SGLT2 inhibition and glucagon secretion in human islets. Diabetes, 69(5), 864-866. https://doi.org/10.2337/dbi19-0035

Dharmaraj, P., Gorvin, C. M., Soni, A., Nelhans, N., Olesen, M., Boon, H., Cranston, T., Thakker, R., & Hannan, F. (2020). Neonatal hypocalcemic seizures in offspring of a mother with familial hypocalciuric hypercalcemia type 1 (FHH1). Journal of Clinical Endocrinology and Metabolism, 105(5), 1393–1400. https://doi.org/10.1210/clinem/dgaa111

Fountas, A., Lim, E. S., Drake, W. M., Powlson, A. S., Gurnell, M., Martin, N. M., Seejore, K., Murray, R. D., MacFarlane, J., Ahluwalia, R., Swords, F., Ashraf, M., Pal, A., Chong, Z., Freel, M., Balafshan, T., Purewal, T. S., Speak, R. G., Newell-Price, J., ... Karavitaki, N. (2020). Outcomes of patients with Nelson’s syndrome after primary treatment: a multicenter study from 13 UK Pituitary centers. Journal of Clinical Endocrinology and Metabolism, 105(5), 1527–1537. https://doi.org/10.1210/clinem/dgz200

Hodson, D., Pickford, P., Lucey, M. A., Fang, Z., Bitsi, S., De La Serna, B., Broichhagen, J., Minnion, J., Rutter, G., Bloom, S., Tomas, A., & Jones, B. (2020). Signalling, trafficking and glucoregulatory properties of glucagon-like peptide-1 receptor agonists exendin-4 and lixisenatide. Manuscript submitted for publication.

El-gamal, M. I., Zaraei, S., Foster, P. A., Anbar, H. S., El-gamal, R., El-awady, R., & Potter, B. V. L. (2020). A new series of aryl sulfamate derivatives: design, synthesis, and biological evaluation. Bioorganic & Medicinal Chemistry, 28(8), [115406]. https://doi.org/10.1016/j.bmc.2020.115406

Fang, Z., Chen, S., Pickford, P., Broichhagen, J., Hodson, D., Corrêa, I. R., Kumar, S., Gorlitz, F., Dunsby, C., French, P., Rutter, G., Tan, T. M., Bloom, S. R., Tomas, A., & Jones, B. (2020). The influence of peptide context on signalling and trafficking of glucagon-like peptide-1 receptor biased agonists. ACS Pharmacology & Translational Science, 3(2), 345–360. https://doi.org/10.1021/acsptsci.0c00022

Toulis, K., Nirantharakumar, K., Pourzitaki, C., Barnett, AH., & Tahrani, A. (2020). Glucokinase activators for type 2 diabetes: challenges and future developments. Drugs, 8, 467–475. https://doi.org/10.1007/s40265-020-01278-z

Welford, A. E., Lanham-New, S., Lord, J., Doyle, A., Robinson, J., Nightingale, P., Gittoes, N., & Greig, C. A. (2020). Influence of combined vitamin D3 supplementation and resistance exercise training on musculoskeletal health in older men and women (EXVITD): protocol for a randomised controlled trial. BMJ open, 10(3), [e033824]. https://doi.org/10.1136/bmjopen-2019-033824

Manojlovic-Gacic, E., Rostami, E., Karavitaki, N., & Casar-Borota, O. (2020). Histopathology of parasellar neoplasms. Neuroendocrinology. https://doi.org/10.1159/000507084

Foster, M., Taylor, A., Bishop, J., Gilligan, L., Bion, J., Lord, J., & Arlt, W. (2020). Mapping the steroid response to major trauma from injury to recovery: a prospective cohort study. Journal of Clinical Endocrinology and Metabolism, 105(3), [dgz302]. https://doi.org/10.1210/clinem/dgz302

Chortis, V., Bancos, I., Nijman, T., Gilligan, L., Taylor, A., Ronchi, C., O'Reilly, M., Schreiner, J., Asia, M., Riester, A., Perotti, P., Libe, R., Quinkler, M., Canu, L., Paiva, I., Bugalho, M. J., Kastelan, D., Dennedy, M. C., Sherlock, M., ... Arlt, W. (2020). Urine steroid metabolomics as a novel tool for detection of recurrent adrenocortical carcinoma. Journal of Clinical Endocrinology and Metabolism, 105(3), e303–e314. https://doi.org/10.1210/clinem/dgz141

Doig, C. L., Zielinska, A. E., Fletcher, R. S., Oakey, L. A., Elhassan, Y. S., Garten, A., Cartwright, D., Heising, S., Alsheri, A., Watson, D. G., Prehn, C., Adamski, J., Tennant, D. A., & Lavery, G. G. (2020). Induction of the nicotinamide riboside kinase NAD⁺ salvage pathway in a model of sarcoplasmic reticulum dysfunction. Skeletal Muscle, 10(1), [5]. https://doi.org/10.1186/s13395-019-0216-z

Gittoes, N., Lord, J., Doyle, A., Robinson, J., Nightingale, P., Greig, C., Welford, A., & Lanham-New, S. (Accepted/In press). The influence of combined vitamin D3 supplementation and resistance exercise training on musculoskeletal health in older men and women (EXVITD): protocol for a randomized controlled trial. BMJ open.

Altieri, B., Sbiera, S., Herterich, S., De Francia, S., Della Casa, S., Calabrese, A., Pontecorvi, A., Quinkler, M., Kienitz, T., Mannelli, M., Canu, L., Angelousi, A., Chortis, V., Kroiss, M., Terzolo, M., Fassnacht, M., & Ronchi, C. L. (2020). Effects of germline CYP2W1*6 and CYP2B6*6 single nucleotide polymorphisms on mitotane treatment in adrenocortical carcinoma: a multicenter ENSAT study. Cancers, 12(2), [359]. https://doi.org/10.3390/cancers12020359, https://doi.org/10.3390/cancers12020359  

Tresoldi, A., Sumilo, D., Perrins, M., Toulis, K., Prete, A., Reddy, N., Wass, J., Arlt, W., & Nirantharakumar, K. (2020). Increased infection risk in Addison's disease and congenital adrenal hyperplasia: a primary care database cohort study. Journal of Clinical Endocrinology and Metabolism, 105(2), 1-2. [dgz006]. https://doi.org/10.1210/clinem/dgz006

Singh, P., Subramanian, A., Adderley, N., Gokhale, K., Shinghal, R., Bellary, S., Nirantharakumar, K., & Tahrani, A. (2020). Impact of bariatric surgery on cardiovascular outcomes and mortality: a population‐based cohort study. British Journal of Surgery. https://doi.org/10.1002/bjs.11433

Gurney, S., Ramalingam, S., Thomas, A., Sinclair, A., & Mollan, S. (2020). Exploring the current management idiopathic intracranial hypertension, and understanding the role of dural venous sinus stenting. Eye and Brain, 2020(12). https://doi.org/10.2147/EB.S193027

Markey, K., Mitchell, J., Botfield, H., Ottridge, R., Matthews, T., Krishnan, A., Woolley, R., Westgate, C., Yiangou, A., Alimajstorovic, Z., Shah, P., Rick, C., Ives, N., Taylor, A., Gilligan, L., Jenkinson, C., Arlt, W., Scotton, W., Fairclough, R. J., ... Sinclair, A. (2020). 11β-hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial. Brain Communications, 2(1), [fcz050]. https://doi.org/10.1093/braincomms/fcz050

Sinclair, A., Alimajstorovic, Z., Westgate, C., Jensen, R. H., Eftekhari, S., Mitchell, J., Vijay, V., & Mollan, S. (2020). Guide to preclinical models used to study the pathophysiology of idiopathic intracranial hypertension. Eye. https://doi.org/10.1038/s41433-019-0751-1

Fountas, A., Van Uum, S., & Karavitaki, N. (2020). Opioid-induced endocrinopathies. The Lancet Diabetes and Endocrinology, 8(1), 68-80. https://doi.org/10.1016/S2213-8587(19)30254-2

Parsons, C., Harvey, N., & Gittoes, N. (2020). Systematic screening using FRAX® leads to increased use of, and adherence to, anti-osteoporosis medications: an analysis of the UK SCOOP trial. Osteoporosis International, 31(1), 67-75. https://doi.org/10.1007/s00198-019-05142-z

Black, J. K., Whittaker, A. C., Tahrani, A. A., & Balanos, G. M. (2020). The implementation of a physical activity intervention in adults with Obstructive Sleep Apnoea over the age of 50 years: a feasibility uncontrolled clinical trial. BMC Sports Science, Medicine and Rehabilitation, 12, 46. https://doi.org/10.1186/s13102-020-00195-8

Kahal, H., Tahrani, A. A., Kyrou, I., Dimitriadis, G. K., Kimani, P. K., Barber, T. M., Nicholls, M., Ali, A., Weickert, M. O., & Randeva, H. S. (2020). The relationship between obstructive sleep apnoea and quality of life in women with polycystic ovary syndrome: a cross-sectional study. Therapeutic Advances in Endocrinology and Metabolism, 11, 2042018820906689. https://doi.org/10.1177/2042018820906689

Kahal, H., Tahrani, A. A., Kyrou, I., Dimitriadis, G. K., Kimani, P. K., Barber, T. M., Nicholls, M., Ali, A., Weickert, M. O., & Randeva, H. S. (2020). The relationship between obstructive sleep apnoea and quality of life in women with polycystic ovary syndrome: a cross-sectional study. Therapeutic Advances in Endocrinology and Metabolism, 11, 2042018820906689. https://doi.org/10.1177/2042018820906689

Viloria, K., Nasteska, D., Briant, L. J. B., Heising, S., Larner, D., Fine, N. H. F., Ashford, F. B., Xavier, G. D. S., Ramos, M. J., Fox, J. E. M., MacDonald, P. E., Akerman, I., Lavery, G. G., Flaxman, C., Morgan, N. G., Richardson, S. J., Hewison, M., & Hodson, D. J. (2019, Dec 19). Vitamin D-binding protein is required for the maintenance of α-cell function and glucagon secretion. https://doi.org/10.1101/2019.12.19.881185

Samperi, I., Lithgow, K., & Karavitaki, N. (2019). Hyperprolactinaemia. Journal of Clinical Medicine, 8(12), [2203]. https://doi.org/10.3390/jcm8122203

Grienke, U., Kaserer, T., Kirchweger, B., Lambrinidis, G., Kandel, R. T., Foster, P., Schuster, D., Mikros, E., & Rollinger, J. M. (2019). Steroid sulfatase inhibiting lanostane triterpenes – structure activity relationship and in silico insights. Bioorganic Chemistry, 95, [103495]. https://doi.org/10.1016/j.bioorg.2019.103495

Crowe, F., Thayakaran, T., Gittoes, N., Hewison, M., Thomas, G. N., Scragg, R., & Nirantharakumar, K. (2019). Non-linear associations of 25-hydroxyvitamin D concentrations with risk of cardiovascular disease and all-cause mortality: results from The Health Improvement Network (THIN) database. The Journal of Steroid Biochemistry and Molecular Biology, 195, [105480]. https://doi.org/10.1016/j.jsbmb.2019.105480

Storbeck, K-H., Schiffer, L., Baranowski, E., Chortis, V., Prete, A., Barnard, L., Gilligan, L., Taylor, A., Idkowiak, J., Arlt, W., & Shackleton, C. (2019). Steroid metabolome analysis in disorders of adrenal steroid biosynthesis and metabolism. Endocrine Reviews, 40(6), 1605-1625. https://doi.org/10.1210/er.2018-00262

Alexandraki, K. I., Kaltsas, G. A., Karavitaki, N., & Grossman, A. (2019). The medical therapy of craniopharyngiomas: the way ahead. Journal of Clinical Endocrinology and Metabolism, 104(12), 5751–5764. https://doi.org/10.1210/jc.2019-01299

Webster, J., Fenton, C., Langen, R., & Hardy, R. (2019). Exploring the interface between inflammatory and therapeutic glucocorticoid induced bone and muscle loss. International Journal of Molecular Sciences, 20(22), [5768]. https://doi.org/10.3390/ijms20225768

Moi, D., Foster, P., Rimmer, L., Jaffri, A., Deplano, A., Balboni, G., Onnis, V., & Potter, B. V. L. (2019). Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors. European Journal of Medicinal Chemistry, 182, [111614]. https://doi.org/10.1016/j.ejmech.2019.111614

Schiffer, L., Barnard, L., Baranowski, E., Gilligan, L., Taylor, A., Arlt, W., Shackleton, C., & Storbeck, K-H. (2019). Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: a comprehensive review. The Journal of Steroid Biochemistry and Molecular Biology, 194, [105439]. https://doi.org/10.1016/j.jsbmb.2019.105439

Lithgow, K., Batra, R., Matthews, T., & Karavitaki, N. (2019). Management of endocrine disease: visual morbidity in patients with pituitary adenoma. European Journal of Endocrinology, 181(5), R185-R197. https://doi.org/10.1530/EJE-19-0349

Torlinska, B., Nichols, L., Mohammed, M. A., McCabe, C., & Boelaert, K. (2019). Patients treated for hyperthyroidism are at increased risk of becoming obese: findings from a large prospective secondary care cohort. Thyroid, 29(10), 1380-1389. https://doi.org/10.1089/thy.2018.0731

Lippincott, M. F., León, S., Chan, Y., Fergani, C., Talbi, R., Farooqi, I. S., Jones, C. M., Arlt, W., Stewart, S. E., Cole, T. R., Terasawa, E., Hall, J. E., Shaw, N. D., Navarro, V. M., & Seminara, S. B. (2019). Hypothalamic reproductive endocrine pulse generator activity independent of neurokinin B and dynorphin signaling. Journal of Clinical Endocrinology and Metabolism, 104(10), 4304-4318. https://doi.org/10.1210/jc.2019-00146

Shad, B., Thompson, J., Holwerda, A., Stocks, B., Elhassan, Y., Philp, A., van Loon, L., & Wallis, G. (2019). One week of step reduction lowers myofibrillar protein synthesis rates in young men. Medicine and Science in Sports and Exercise, 51(10), 2125-2134. https://doi.org/10.1249/MSS.0000000000002034

Ronchi, C. (2019). cAMP/protein kinase A signalling pathway and adrenocortical adenomas. Current Opinion in Endocrine and Metabolic Research, 8, 15-21. https://doi.org/10.1016/j.coemr.2019.06.003

Thompson, R. J., Fletcher, A., Brookes, K., Nieto, H., Alshahrani, M. M., Mueller, J. W., Fine, N. H. F., Hodson, D. J., Boelaert, K., Read, M. L., Smith, V. E., & McCabe, C. J. (2019). Dimerization of the sodium/iodide symporter. Thyroid, 29(10), 1485-1498. https://doi.org/10.1089/thy.2019.0034

Lavrentaki, A., Thomas, T., Subramanian, A., Valsamakis, G., Thomas, N., Toulis, K. A., Wang, J., Daly, B., Saravanan, P., Sumilo, D., Mastorakos, G., Tahrani, A. A., & Nirantharakumar, K. (2019). Increased risk of non-alcoholic fatty liver disease in women with gestational diabetes mellitus: A population-based cohort study, systematic review and meta-analysis. Journal of Diabetes and its Complications, 33(10), 107401. https://doi.org/10.1016/j.jdiacomp.2019.06.006

Karavitaki, N., & Souteiro, P. (2019). Dopamine agonist resistant prolactinomas - any alternative medical treatment? Pituitary. https://doi.org/10.1007/s11102-019-00987-3

de Vries, F., Bruin, M., Lobatto, D. J., Dekkers, O., Schoones, J. W., van Furth, W. R., Pereira, A., Karavitaki, N., Biermasz, N. R., & Zamanipoor Najafabadi, A. H. (2019). Opioids and their endocrine effects: a systematic review and meta-analysis. The Journal of clinical endocrinology and metabolism, [dgz022]. https://doi.org/10.1210/clinem/dgz022

Hodson, D. (2019). Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta-cell dysfunction in type 2 diabetes. Diabetologia.

Thayakaran, T., Adderley, N., Sainsbury, C., Torlinska, B., Boelaert, K., Sumilo, D., Price, M., Thomas, G. N., Toulis, K., & Nirantharakumar, K. (2019). Thyroid replacement therapy, thyroid stimulating hormone concentrations, and long term health outcomes in patients with hypothyroidism: longitudinal study. BMJ, 366, [l4892]. https://doi.org/10.1136/bmj.l4892

Schiffer, L., Adaway, J. E., Arlt, W., & Keevil, B. G. (2019). A liquid chromatography-tandem mass spectrometry assay for the profiling of classical and 11-oxygenated androgens in saliva. Annals of Clinical Biochemistry, 56(5), 564-573. https://doi.org/0.1177/0004563219847498

Adderley, N., Subramanian, A., Nirantharakumar, K., Yiangou, A., Gokhale, K., Mollan, S., & Sinclair, A. (2019). Association between idiopathic intracranial hypertension and risk of cardiovascular diseases in women in the United Kingdom. JAMA Neurology, 76(9), 1088-1098. https://doi.org/10.1001/jamaneurol.2019.1812

Elhassan, Y. S., Kluckova, K., Fletcher, R. S., Schmidt, M. S., Garten, A., Doig, C. L., Cartwright, D. M., Oakey, L., Burley, C. V., Jenkinson, N., Wilson, M., Lucas, S. J. E., Akerman, I., Seabright, A., Lai, Y., Tennant, D. A., Nightingale, P., Wallis, G. A., Manolopoulos, K. N., ... Lavery, G. G. (2019). Nicotinamide riboside augments the aged human skeletal muscle NAD⁺ metabolome and induces transcriptomic and anti-inflammatory signatures. Cell Reports, 28(7), 1717-1728.e6. https://doi.org/10.1016/j.celrep.2019.07.043

Gorvin, C. M. (2019). Molecular and clinical insights from studies of calcium-sensing receptor mutations. Journal of Molecular Endocrinology, 63(2), R1-R16. https://doi.org/10.1530/JME-19-0104

Toulis, K. A., Viola, D., Gkoutos, G., Keerthy, D., Boelaert, K., & Nirantharakumar, K. (2019). Risk of incident circulatory disease in patients treated for differentiated thyroid carcinoma with no history of cardiovascular disease. Clinical Endocrinology, 91(2), 323-330. https://doi.org/10.1111/cen.13990

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Tamblyn, J., Jeffery, L., Susarla, R., Lissauer, D., Coort, S. L., Munoz Garcia, A., Knoblich, K., Fletcher, A., Bulmer, JN., Kilby, M., & Hewison, M. (2019). Transcriptomic analysis of vitamin D responses in uterine and peripheral NK cells. Reproduction, 158(2), 211-221. https://doi.org/10.1530/REP-18-0509

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Nirantharakumar, K., Subramanian, A., Gokhale, K., Mollan, S., & Sinclair, A. (Accepted/In press). Idiopathic intracranial hypertension and risk of cardiovascular diseases in women: UK population based matched cohort study. JAMA Neurology.

Elhassan, Y., Alahdab, F., Prete, A., Delivanis, D., Khanna, A., Prokop, L., Murad, M. H., O'reilly, M., Arlt, W., & Bancos, I. (2019). Natural history of adrenal incidentalomas with and without mild autonomous cortisol excess: a systematic review and meta-analysis. Annals of internal medicine, 171(2), 107-116. https://doi.org/10.7326/M18-3630

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Thomson, W., Jabbari, S., Taylor, A. E., Arlt, W., & Smith, D. (2019). Simultaneous parameter estimation and variable selection via the logit-normal continuous analogue of the spike-and-slab prior. Journal of The Royal Society Interface, 16(150), 20180572. [20180572]. https://doi.org/10.1098/rsif.2018.0572

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O'reilly, M., Glisic, M., Kumarendran, B., Subramanian, A., Manolopoulos, K., Tahrani, A., Keerthy, D., Muka, T., Toulis, K., Hanif, W., Thomas, G. N., Franco, O. H., Arlt, W., & Nirantharakumar, K. (2019). Serum testosterone, sex hormone-binding globulin and sex-specific risk of incident type 2 diabetes in a retrospective primary care cohort. Clinical Endocrinology, 90(1), 145-154. https://doi.org/10.1111/cen.13862

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Mollan, S. P., Hornby, C., Mitchell, J., & Sinclair, A. J. (2018). Evaluation and management of adult idiopathic intracranial hypertension. Practical Neurology, 18(6), 485-488. https://doi.org/10.1136/practneurol-2018-002009

Hornby, C., Mollan, S., Botfield, H., OʼReilly, M. W., & Sinclair, A. (2018). Metabolic Concepts in Idiopathic Intracranial Hypertension and Their Potential for Therapeutic Intervention. Journal of Neuro-Ophthalmology, 38(4), 522–530. https://doi.org/10.1097/WNO.0000000000000684

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Mollan, S., Aguiar, M., Evison, F., Frew, E., & Sinclair, A. (2018). The expanding burden of Idiopathic Intracranial Hypertension. Eye. https://doi.org/10.1038/s41433-018-0238-5

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Bunte, K., Smith, D., Chappell, M. J., Hassan-Smith, Z., Tomlinson, J., Arlt, W., & Tino, P. (2018). Learning pharmacokinetic models for in vivo glucocorticoid activation. Journal of Theoretical Biology, 455, 222-231. https://doi.org/10.1016/j.jtbi.2018.07.025

Jenkinson, C., Taylor, A., Storbeck, K-H., & Hewison, M. (2018). Data comparing the separation and elution of vitamin D metabolites on an ultra performance supercritical fluid chromatography tandem-mass spectrometer (UPSFC-MS/MS) compared to liquid chromatography (LC) and data presenting approaches to UPSFC method optimization. Data in Brief, 20, 426-435. https://doi.org/10.1016/j.dib.2018.08.027

Fountas, A., Chai, S. T., Kourkouti, C., & Karavitaki, N. (2018). Mechanisms in endocrinology: endocrinology of opioids. European Journal of Endocrinology, 179(4), R183–R196. https://doi.org/10.1530/EJE-18-0270

Mollan, SP., Davis, B., Silver, NC., Shaw, S., Malucci, C., Wakerley, BR., Krishnan, A., Chavda, S., Ramalingam, S., Edwards, J., Hemmings, K., Williamson, M., Burdon, MA., Hassan-Smith, Z., Digre, K., Liu, GT., Jensen, R., & Sinclair, A. (2018). Idiopathic intracranial hypertension: consensus guidelines on management. Journal of Neurology Neurosurgery and Psychiatry, 89, 1088-1100. https://doi.org/10.1136/jnnp-2017-317440

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Willemsen, R. H., Burling, K., Barker, P., Ackland, F., Dias, R. P., Edge, J., Smith, A., Todd, J., Lopez, B., Mander, A. P., Guy, C., & Dunger, D. B. (2018). Frequent Monitoring of C-Peptide Levels in Newly Diagnosed Type 1 Subjects Using Dried Blood Spots Collected at Home. The Journal of clinical endocrinology and metabolism, 103(9), 3350-3358. https://doi.org/10.1210/jc.2018-00500

Sahloul, M., Karim, A., Chohan, K. S., Tahrani, A. A., Mahawar, K., Richardson, M., Ludwig, C., Daskalakis, M., & Singhal, R. (2018). Roux-en-Y Gastric Bypass: Does the Direction of Staples Matter? Obesity surgery, 28(9), 2868-2873. https://doi.org/10.1007/s11695-018-3275-z

Chetan, M. R., Charlton, M. H., Thompson, C., Dias, R. P., Andrews, R. C., & Narendran, P. (2018). The Type 1 diabetes 'honeymoon' period is five times longer in men who exercise: a case-control study. Diabetic Medicine. https://doi.org/10.1111/dme.13802

Adolf, C., Köhler, A., Franke, A., Lang, K., Riester, A., Löw, A., Heinrich, D. A., Bidlingmaier, M., Treitl, M., Ladurner, R., Beuschlein, F., Arlt, W., & Reincke, M. (2018). Cortisol excess in patients with primary aldosteronism impacts on left ventricular hypertrophy. Journal of Clinical Endocrinology and Metabolism, 103(12), 4543-4552. https://doi.org/doi.org/10.1210/jc.2018-00617

Foster, P., & Mueller, J. W. (2018). Sulfation pathways: Insights into steroid sulfation and desulfation pathways. Journal of Molecular Endocrinology, 61(2), T271–T283. https://doi.org/10.1530/JME-18-0086

Hardy, R., Fenton, C., Croft, A., Naylor, A., Begum, R., Desanti, G., Buckley, C., Lavery, G., Cooper, M. S., & Raza, K. (2018). 11 beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis. Journal of Autoimmunity, 92, 104-113. https://doi.org/10.1016/j.jaut.2018.05.010

Chortis, V., Taylor, A., Doig, C., Walsh, M., Meimaridou, E., Jenkinson, C., Rodriguez Blanco, G., Ronchi, C., Jaffri, A., Metherell, L. A., Hebenstreit, D., Dunn, W., Arlt, W., & Foster, P. (2018). Nicotinamide nucleotide transhydrogenase as a novel treatment target in adrenocortical carcinoma. Endocrinology, 159(8), 2836–2849. https://doi.org/10.1210/en.2018-00014

Fehrentz, T., Huber, F., Hartrampf, N., Bruegmann, T., Frank, J., Fine, N., Malan, D., Danzl, J., Tikhonov, D., Sumser, M., Sasse, P., Hodson, D., Zhorov, B., Nikolaj, K., & Trauner, D. (2018). Optical control of L-Type Ca2+ channels using a diltiazem photoswitch. Nature Chemical Biology, 14, 764-767. https://doi.org/10.1038/s41589-018-0090-8

De Bray, A., Hassan-Smith, Z., Dirie, J., Littleton, E., Chavda, S., Ayuk, J., Sanghera, P., & Karavitaki, N. (2018). Macroprolactinoma causing VI, X, XII cranial nerve palsies nearly 30 years after initial treatment. Endocrinology, Diabetes and Metabolism Case Reports , 2018(1). https://doi.org/10.1530/EDM-18-0053

Hodson, D., & Nasteska, D. (2018). The role of beta cell heterogeneity in islet function and insulin release. Journal of Molecular Endocrinology, 61, R43-R60. https://doi.org/10.1530/JME-18-0011

Kahal, H., Kyrou, I., Uthman, O., Brown, A., Johnson, S., Wall, P., Metcalfe, A., Tahrani, A. A., & Randeva, H. S. (2018). The association between obstructive sleep apnea and metabolic abnormalities in women with polycystic ovary syndrome: a systematic review and meta-analysis. Sleep, 41(7), [zsy085]. https://doi.org/10.1093/sleep/zsy085

Hodson, D. (2018). Androgen excess in pancreatic β-cells and neurons predisposes female mice to type 2 diabetes. JCI Insight. https://doi.org/10.1172/jci.insight.98607.

Yiangou, A., Mitchell, J., Markey, K. A., Scotton, W., Nightingale, P., Botfield, H., Ottridge, R., Mollan, S. P., & Sinclair, A. J. (2018). Therapeutic lumbar puncture for headache in idiopathic intracranial hypertension: Minimal gain, is it worth the pain? Cephalalgia. https://doi.org/10.1177/0333102418782192

Scotton, W. J., Botfield, H. F., Westgate, C. S., Mitchell, J. L., Yiangou, A., Uldall, M. S., Jensen, R. H., & Sinclair, A. J. (2018). Topiramate is more effective than acetazolamide at lowering intracranial pressure. Cephalalgia. https://doi.org/10.1177/0333102418776455

Santharam, S., Fountas, A., Tampourlou, M., Arlt, W., Ayuk, J., Gittoes, N., Toogood, A., & Karavitaki, N. (2018). Impact of menopause on outcomes in prolactinomas after dopamine agonist treatment withdrawal. Clinical Endocrinology. https://doi.org/10.1111/cen.13765

Schiffer, L., Adaway, J. E., Baranowski, E., Arlt, W., & Keevil, B. G. (2018). A novel high-throughput assay for the measurement of salivary progesterone by liquid chromatography tandem mass spectrometry. Annals of Clinical Biochemistry. https://doi.org/10.1177/0004563218780904

Mueller, J. W., Idkowiak, J., Gesteira, T. F., Vallet, C., Hardman, R., van den Boom, J., Dhir, V., Knauer, S. K., Rosta, E., & Arlt, W. (2018). Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1. Journal of Biological Chemistry, 293(25), 9724-9735. https://doi.org/10.1074/jbc.RA118.002248

Scotton, W. J., Mollan, S. P., Botfield, H., Yiangou, A., Markey, K., Sinclair, A. J., Walters, T., Doughty, S., & Williamson, S. (2018). Characterising the patient experience of diagnostic lumbar puncture in idiopathic intracranial hypertension: a cross-sectional online survey. BMJ open, 8(5), [e020445]. https://doi.org/10.1136/bmjopen-2017-020445

Janjuha, S., Pal Singh, S., Tsakmaki, A., Mousavy Gharavy, N., Murawala, P., Konantz, J., Birke, S., Hodson, D., Rutter, G., Bewick, G., & Ninov, N. (2018). Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish. eLife. https://doi.org/10.7554/eLife.32965

Taylor, A., Storbeck, K-H., Hewison, M., & Jenkinson, C. (2018). Analysis of multiple vitamin D metabolites by ultra-performance supercritical fluid chromatography-tandem mass spectrometry (UPSFC-MS/MS). Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1087-1088, 43-48. https://doi.org/10.1016/j.jchromb.2018.04.025

Benninger, R., & Hodson, D. (2018). New Understanding of β-Cell Heterogeneity and In Situ Islet Function. Diabetes, 537-547. https://doi.org/10.2337/dbi17-0040

Karamat, M. A., Dar, S., Bellary, S., & Tahrani, A. A. (2018). Clinical and Cost Implications of Insulin Degludec in Patients with Type 1 Diabetes and Problematic Hypoglycemia: A Quality Improvement Project. Diabetes therapy : research, treatment and education of diabetes and related disorders, 9(2), 839-849. https://doi.org/10.1007/s13300-018-0400-x

Tampourlou, M., Fountas, A., Ntali, G., & Karavitaki, N. (2018). Mortality in patients with non-functioning pituitary adenoma. Pituitary, 21(2), 203–207. https://doi.org/10.1007/s11102-018-0863-9

Webb, E., Elliott, L., Carlin, D., Wilson, M., Hall, K., Netherton, J., Reed, J., Barrett, T., Salwani, V., Clayden, J., Arlt, W., Krone, N., Peet, A., & Wood, A. (2018). Quantitative brain MRI in congenital adrenal hyperplasia: in vivo assessment of the cognitive and structural impact of steroid hormones. Journal of Clinical Endocrinology and Metabolism, 103(4), 1330-1341. https://doi.org/10.1210/jc.2017-01481, https://doi.org/10.1210/jc.2017-01481

Hodson, D., & Da Silva Xavier, G. (2018). Mouse models of peripheral metabolic disease. Best practice & research. Clinical endocrinology & metabolism. https://doi.org/10.1016/j.beem.2018.03.009

Gorvin, C. (2018). Insights into calcium-sensing receptor trafficking and biased signalling by studies of calcium homeostasis. Journal of Molecular Endocrinology. https://doi.org/10.1530/JME-18-0049

Kumarendran, B., O'Reilly, M., Manolopoulos, K., Toulis, K., Gokhale, K., Sitch, A., Wijeyaratne, C. N., Coomarasamy, A., Arlt, W., & Nirantharakumar, K. (2018). Polycystic ovary syndrome, androgen excess, and the risk of nonalcoholic fatty liver disease in women: a longitudinal study based on a United Kingdom primary care database. PLoS Medicine, 15(3), [e1002542]. https://doi.org/10.1371/journal.pmed.1002542

Mistry, P., Currie, V., Super, P., le Roux, C. W., Tahrani, A. A., & Singhal, R. (2018). Changes in glycaemic control, blood pressure and lipids 5 years following laparoscopic adjustable gastric banding combined with medical care in patients with type 2 diabetes: a longitudinal analysis. Clinical Obesity. https://doi.org/10.1111/cob.12244

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Chortis, V., Johal, N. J., Bancos, I., Evans, M., Skordilis, K., Guest, P., Cullen, M. H., Porfiri, E., & Arlt, W. (2018). Mitotane treatment in patients with metastatic testicular Leydig cell tutor associated with severe androgen excess. European Journal of Endocrinology. https://doi.org/10.1530/EJE-17-0542

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Tang, T., Abbott, S., le Roux, C. W., Wilson, V., Singhal, R., Bellary, S., & Tahrani, A. A. (2017). Preoperative weight loss with glucagon-like peptide-1 receptor agonist treatment predicts greater weight loss achieved by the combination of medical weight management and bariatric surgery in patients with type 2 diabetes: A longitudinal analysis. Diabetes, Obesity and Metabolism. https://doi.org/10.1111/dom.13131

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Ganguly, A., Tamblyn, J. A., Finn-Sell, S., Chan, S-Y., Westwood, M., Gupta, J., Kilby, M., Gross, S. R., & Hewison, M. (2017). Vitamin D, the placenta and early pregnancy: effects on trophoblast function. Journal of Endocrinology. https://doi.org/10.1530/JOE-17-0491

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O'reilly, M., Kempegowda, P., Walsh, M., Taylor, A., Manolopoulos, K., Allwood, J. W., Semple, R. K., Hebenstreit, D., Dunn, W., Tomlinson, J., & Arlt, W. (2017). AKR1C3-mediated adipose androgen generation drives lipotoxicity in women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism, 102(9), 3327–3339. https://doi.org/10.1210/jc.2017-00947

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Botfield, H. F., Uldall, M. S., Westgate, C. S. J., Mitchell, J. L., Hagen, S. M., Gonzalez, A. M., Hodson, D. J., Jensen, R. H., & Sinclair, A. J. (2017). A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus. Science Translational Medicine, 9(404), [eaan0972]. https://doi.org/10.1126/scitranslmed.aan0972

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Fletcher, R. S., Ratajczak, J., Doig, C. L., Oakey, L. A., Callingham, R., Da Silva Xavier, G., Garten, A., Elhassan, Y. S., Redpath, P., Migaud, M. E., Philp, A., Brenner, C., Canto, C., & Lavery, G. G. (2017). Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. Molecular metabolism, 6(8), 819-832. https://doi.org/10.1016/j.molmet.2017.05.011

Jones, B. J., Scopelliti, R., Tomas, A., Hodson, D. J., & Broichhagen, J. (2017). Potent prearranged positive allosteric modulators of the glucagon-like peptide 1 receptor. Open Chemistry, 6(4), 501–505. https://doi.org/10.1002/open.201700062

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Santharam, S., Tampourlou, M., Arlt, W., Gittoes, N., Toogood, A. A., Webster, R., & Karavitaki, N. (2017). Prolactinomas diagnosed in the postmenopausal period: clinical phenotype and outcomes. Clinical Endocrinology. https://doi.org/10.1111/cen.13399

Liu, N., Larner, D., Yao, Q., Chun, R., Ouyang, Y. B., Zhou, R., Tamblyn, J., Wagner, C. L., & Hewison, M. (2017). Vitamin D-deficiency and sex-specific dysregulation of placental inflammation. The Journal of Steroid Biochemistry and Molecular Biology. https://doi.org/10.1016/j.jsbmb.2017.06.012, https://doi.org/10.1016/j.jsbmb.2017.06.012

Zielinska, A., Fletcher, R., Sherlock, M., Doig, C., & Lavery, G. (2017). Cellular and genetic models of H6PDH and 11β-HSD1 function in skeletal muscle. Cell Biochemistry & Function, 35(5), 269-277. https://doi.org/10.1002/cbf.3272

Hirschmann, F., Krause, F., Baruch, P., Chizhov, I., Mueller, J. W., Manstein, D. J., Papenbrock, J., & Fedorov, R. (2017). Structural and biochemical studies of sulphotransferase 18 from Arabidopsis thaliana explain its substrate specificity and reaction mechanism. Scientific Reports, 7, [4160]. https://doi.org/10.1038/s41598-017-04539-2

Kahal, H., Kyrou, I., Tahrani, A. A., & Randeva, H. S. (2017). Obstructive Sleep Apnoea and Polycystic Ovary Syndrome; a comprehensive review of clinical interactions and underlying pathophysiology. Clinical Endocrinology. https://doi.org/10.1111/cen.13392

Hornby, C., Botfield, H., O'reilly, M., Westgate, C., Mitchell, J., Mollan, S., Manolopoulos, K., Tomlinson, J., & Sinclair, A. (2017). Evaluating the fat distribution in Idiopathic Intracranial Hypertension using Dual energy X-ray absorptiometry scanning. Neuro-Ophthalmology. https://doi.org/10.1080/01658107.2017.1334218

Tahrani, A. A. (2017). Novel therapies in type 2 diabetes: insulin resistance. Practical Diabetes, 34(5), 161-166a. https://doi.org/10.1002/pdi.2109

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Altaf, QA., Dodson, P., Ali, A., Raymond, NT., Wharton, H., Fellows, H., Hampshire-Bancroft, R., Shah, M., Shepherd, E., Miah, J., Barnett, AH., & Tahrani, AA. (2017). Obstructive sleep apnoea and retinopathy in patients with Type 2 diabetes: A longitudinal study. American Journal of Respiratory and Critical Care Medicine, 196(7). https://doi.org/10.1164/rccm.201701-0175oc

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Bancos, I., & Arlt, W. (2017). Diagnosis of a malignant adrenal mass: the role of urinary steroid metabolite profiling. Current Opinion in Endocrinology and Diabetes, 24(3), 200–207.

Podewin, T., Broichhagen, J., Frost, C., Groneberg, D., Ast, J., Meyer-Berg, H., Fine, N. H. F., Friebe, A., Zacharias, M., Hodson, D. J., Trauner, D., & Hoffmann-Röder, A. (2017). Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone. Chemical Science, 8(6), 4644-4653. https://doi.org/10.1039/C6SC05044A

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Philp, A. A., Lavery, G. G., & Elhassan, Y. (2017). Targeting NAD+ in Metabolic Disease: New Insights Into an Old Molecule. Endocrine pathology, 1(7), 816-835. https://doi.org/10.1210/js.2017-00092

Naylor, A., Desanti, G., Saghir, A., & Hardy, R. (2017). TNFα depleting therapy improves fertility and animal welfare in TNFα-driven transgenic models of polyarthritis when administered in their routine breeding. Laboratory Animals. https://doi.org/10.1177/0023677217707985

Sharples, A. J., Charalampakis, V., Daskalakis, M., Tahrani, A., & Singhal, R. (2017). Systematic review and meta-analysis of outcomes after revisional bariatric surgery following a failed adjustable gastric band. Obesity surgery. https://doi.org/10.1007/s11695-017-2677-7

Cegla, J., Gardiner, J. V., Hodson, D. J., Marjot, T., McGlone, E. R., Tan, T. M., & Bloom, S. R. (2017). RAMP2 influences glucagon receptor pharmacology via trafficking and signaling. Endocrinology.

O'Reilly, M., Kempegowda, P., Walsh, M., Taylor, A., Manolopoulos, K., Allwood, W., Semple, R., Hebenstreit, D., Dunn, W., Tomlinson, J., & Arlt, W. (2017). AKR1C3-mediated adipose androgen generation drives lipotoxicity in polycystic ovary syndrome. Endocrine Abstracts. https://doi.org/10.1530/endoabs.49.oc3.3

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Tampourlou, M., Arlt, W., Gittoes, N., O'reilly, M., & Karavitaki, N. (2017). Outcome of non-functioning pituitary adenomas that regrow after primary treatment: a study from two large specialist UK centers. Abstract from 19th European Congress of Endocrinology, Lisbon, Portugal. https://doi.org/10.1530/endoabs.49.GP180

Santharam, S., Tampourlou, M., Arlt, W., Ayuk, J., Gittoes, N., Toogood, A., Webster, R., & Karavitaki, N. (2017). Prolactinomas diagnosed after menopause: presentation and outcomes from a large specialist centre. Abstract from 19th European Congress of Endocrinology, Lisbon, Portugal. https://doi.org/10.1530/endoabs.49.EP1051

Lebbe, M., Taylor, A., Visser, J. A., Kirkman-Brown, J., Woodruff, T. K., & Arlt, W. (2017). The steroid metabolome in the isolated ovarian follicle and its response to androgen exposure and antagonism. Endocrinology, 158(5), 1474-1485. https://doi.org/10.1210/en.2016-1851

Arlt, W., Lang, K., Sitch, A., Dietz, A. S., Rhayem, Y., Bancos, I., Feuchtinger, A., Chortis, V., Gilligan, L., Ludwig, P., Riester, A., Asbach, E., Hughes, B., O'Neil, D., Bidlingmaier, M., Tomlinson, J. W., Hassan-Smith, Z., Rees, D. A., Adolf, C., ... Reincke, M. (2017). Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism. JCI Insight, 2(8), [e93136]. https://doi.org/10.1172/jci.insight.93136

Tahrani, A. A. (2017). Ethnic Differences In The Pathogenesis of Obstructive Sleep Apnoea: Exploring Non-Anatomical Factors. Respirology. https://doi.org/10.1111/resp.13057

Mitchell, R. K., Nguyen-Tu, M-S., Chabosseau, P., Callingham, R. M., Pullen, T. J., Cheung, R., Leclerc, I., Hodson, D. J., & Rutter, G. A. (2017). The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis and Ca2+ dynamics in adult mice. Journal of Biological Chemistry. https://doi.org/10.1074/jbc.M117.784629

Manolopoulos, K. N., O'Reilly, M. W., Bujalska, I. J., Tomlinson, J. W., & Arlt, W. (2017). Acute hypercortisolemia exerts depot-specific effects on abdominal and femoral adipose tissue function. Journal of Clinical Endocrinology and Metabolism, 102(4), 1091-1101. https://doi.org/10.1210/jc.2016-3600

Bancos, I., Hazeldine, J., Chortis, V., Hampson, P., Taylor, A. E., Lord, J., & Arlt, W. (2017). Primary adrenal insufficiency is associated with impaired natural killer cell function: a potential link to increased mortality. European Journal of Endocrinology, 176(4), 471-480. https://doi.org/10.1530/EJE-16-0969

Welch, C., Hassan-Smith, Z., Greig, C., Lord, J., & Jackson, T. (2017). Acute Sarcopenia Secondary to Hospitalisation – An Emerging Condition Affecting Older Adults. Aging and Disease, 8(6). https://doi.org/10.14336/AD.2017.0315

Mehta, Z., Johnston, N., Nguyen-Tu, M-S., Broichhagen, J., Schultz, P. G., Larner, D., Leclerc, I., Trauner, D., Rutter, G., & Hodson, D. J. (2017). Remote control of glucose homeostasis in vivo using photopharmacology. Scientific Reports, 7, [291]. https://doi.org/10.1038/s41598-017-00397-0

Tahrani, A. (2017). Peripheral and Autonomic Neuropathy in South Asians and White Caucasians with Type 2 Diabetes Mellitus: Possible Explanations for Epidemiological Differences. Journal of Diabetes Research, [1273789]. https://doi.org/10.1155/2017/1273789

Weigel, M., Hahner, S., Sherlock, M., Agha, A., Behan, L. A., Stewart, P., Arlt, W., Beier, D., Frey, K., Zopf, K., & Quinkler, M. (2017). Immediate versus modified release hydrocortisone in mitotane-treated patients with adrenocortical cancer. Clinical Endocrinology, 86(4), 499-505. https://doi.org/10.1111/cen.13302

Gilligan, L., Gondal, A., Tang, V., Hussain, M. T., Arvaniti, A., Hewitt, A-M., & Foster, P. A. (2017). Estrone sulfate transport and steroid sulfatase activity in colorectal cancer: implications for Hormone Replacement Therapy. Frontiers in Pharmacology, 8, [103]. https://doi.org/10.3389/fphar.2017.00103

O'reilly, M., Kempegowda, P., Jenkinson, C., Taylor, A., Quanson, J. L., Storbeck, K-H., & Arlt, W. (2017). 11-oxygenated C19 steroids are the predominant androgens in polycystic ovary syndrome. The Journal of clinical endocrinology and metabolism, 102(3), 840-848. https://doi.org/10.1210/jc.2016-3285

May, C. J. H., Asis, M., Arlt, W., Guest, P., O'reilly, M., & Karavitaki, N. (2017). Bilateral adrenal haemorrhage. QJM: An International Journal of Medicine, 110(3), 169-171. https://doi.org/10.1093/qjmed/hcw212

Romanò, N., Guillou, A., Hodson, D. J., Martin, A. O., & Mollard, P. (2017). Multiple-scale neuroendocrine signals connect brain and pituitary hormone rhythms. National Academy of Sciences. Proceedings, 114(9), 2379–2382. https://doi.org/10.1073/pnas.1616864114

Hassan-Smith, Z. K., Jenkinson, C., Smith, D., Hernandez, I., Morgan, S., Crabtree, N. J., Gittoes, N., Keevil, B. G., Stewart, P. M., & Hewison, M. (2017). 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression. PLoS ONE, 12(2), [e0170665]. https://doi.org/10.1371/journal.pone.0170665

Poole, V., Fletcher, A., Modasia, B., Sharma, N., Thompson, R., Imruetaicharoenchoke, W., Read, M., Boelaert, K., McCabe, C., & Smith, V. (2017). Pharmacological enhancement of radioiodine uptake using Src kinase inhibitors. Thyroid Research, 10(Suppl 1)(2), 2. [O2]. https://doi.org/10.1186/s13044-016-0036-8

Gittoes, O., & Gittoes, N. (2017). Breathlessness and neck swelling after a rugby game. BMJ, 356, [j311]. https://doi.org/10.1136/bmj.j311

Puar, T., Engels, M., van Herwaarden, A., Sweep, F., Hulsbergen-van de Kaa, C., Kamphuis-van Ulzen, K., Chortis, V., Arlt, W., Stikkelbroeck, N., Claahsen-van der Grinten, H., & Hermus, A. (2017). Bilateral testicular tumors resulting in recurrent Cushing's syndrome after bilateral adrenalectomy. Journal of Clinical Endocrinology and Metabolism, 102(2), 339-344. https://doi.org/10.1210/jc.2016-2702

Tamblyn, J., Susarla, R., Jenkinson, C., Jeffery, L., Ohizua, O., Chun, R., Chan, S. Y., Kilby, M., & Hewison, M. (2017). Dysregulation of maternal and placental vitamin D metabolism in preeclampsia. Placenta, 50, 70-77. https://doi.org/10.1016/j.placenta.2016.12.019

Lavrentaki, A., Karavitaki, N., Paluzzi, A., & Wass, J. A. H. (2017). Epidemiology of Acromegaly: Review of population studies. Pituitary, 20(1), 4–9. https://doi.org/10.1007/s11102-016-0754-x

Dafoulas, G. E., Toulis, K., Mccorry, D., Kumarendran, B., Thomas, G. N., Willis, B. H., Gokhale, K., Gkoutos, G., Narendran, P., & Nirantharakumar, K. (2017). Type 1 diabetes mellitus and risk of incident epilepsy: a population-based, open-cohort study. Diabetologia, 60(2), 258-261. https://doi.org/10.1007/s00125-016-4142-x

Karamat, M. A., Raja, U. Y., Manley, S. E., Jones, A., Hanif, W., & Tahrani, A. A. (2017). Prevalence of undiagnosed type 2 diabetes in patients admitted with acute coronary syndrome: the utility of easily reproducible screening methods. BMC Endocrine Disorders, 17(3), [3]. https://doi.org/10.1186/s12902-017-0153-y

Amin, A., Ali, A., Altaf, QA., Piya, MK., Barnett, AH., Raymond, NT., & Tahrani, AA. (2017). Prevalence and associations of obstructive sleep apnea in South Asians and White Europeans with Type 2 diabetes: A cross-sectional study. The Journal of Clinical Sleep Medicine, 13(4). http://jcsm.aasm.org/ViewAbstract.aspx?pid=30993

Le Tissier, P., Campos, P., Lafont, C., Romano, N., Hodson, D., & Mollard, P. (2017). An updated view of hypothalamic–vascular–pituitary unit function and plasticity. Nature Reviews Endocrinology, 13, 257-267. https://doi.org/10.1038/nrendo.2016.193

Amin, A., Ali, A., Altaf, Q. A., Piya, M. K., Barnett, A. H., Raymond, N. T., & Tahrani, A. A. (2017). Prevalence and associations of obstructive sleep apnea in South Asians and White Europeans with type 2 diabetes: A cross-sectional study. The Journal of Clinical Sleep Medicine, 13(4), 583-589. https://doi.org/10.5664/jcsm.6548

Hornby, C., Mollan, S., Mitchell, J., Markey, K. A., Yangou, A., Wright, B., O'Reilly, M., & Sinclair, A. (2017). What do transgender patients teach us about Idiopathic Intracranial Hypertension? Neuro-Ophthalmology, 41(6), 326-329. https://doi.org/10.1080/01658107.2017.1316744

2016

Doig, C. L., & Lavery, G. G. (2016). PARP Inhibitors: Staying on Target? Cell Chemical Biology, 23(12), 1442-1443. https://doi.org/10.1016/j.chembiol.2016.12.003

Hornby, C., O'Reilly, M., Botfield, H., Markey, K., Kempegowda, P., Taylor, A., Hughes, B., Tomlinson, J., Arlt, W., & Sinclair, A. (2016). The Andro-metabolic signature of Idiopathic Intracranial Hypertension compared to Polycystic Ovary Syndrome and Simple Obesity. Journal of Neurology, Neurosurgery & Psychiatry, 87(12), e1.46-e1. https://doi.org/10.1136/jnnp-2016-315106.14

Hardy, R. S., Doig, C. L., Hussain, Z., O'Leary, M., Morgan, S. A., Pearson, M. J., Naylor, A., Jones, S., Filer, A., Stewart, P. M., Buckley, C. D., Lavery, G. G., Cooper, M. S., & Raza, K. (2016). 11β-hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation. Journal of Pathology, 240(4), 472-483. https://doi.org/10.1002/path.4806

Bancos, I., Alahdab, F., Crowley, R., Chortis, V., Delivanis, D., Erickson, D., Natt, N., Terzolo, M., Arlt, W., Young Jr, W., & Murad, M. H. (2016). Improvement of cardiovascular risk factors after adrenalectomy in patients with adrenal tumors and Subclinical Cushing Syndrome: a systematic review and meta-analysis. European Journal of Endocrinology, 175(6), R283-R295. https://doi.org/10.1530/EJE-16-0465

Altaf, Q. A., Sadiqi, H., Piya, M. K., & Tahrani, A. A. (2016). Foot insensitivity is associated with renal function decline in patients with type 2 diabetes: a cohort study. BMC Endocrine Disorders, 16(1), 64. https://doi.org/10.1186/s12902-016-0147-1

Belli, A., Roper, L. S., Nightingale, P., Su, Z., & Sinclair, A. (2016). Disability from post-traumatic headache is compounded by PTSD. British Medical Journal. http://10.1136/jnnp-2016-315106.72

Jones, C., Mallappa, A., Reisch, N., Nikolaou, N., Krone, N., Hughes, B., O'Neil, D., Whitaker, M. J., Tomlinson, J., Storbeck, K-H., Merke, D. P., Ross, R., & Arlt, W. (2016). Modified release and conventional glucocorticoids and diurnal androgen excretion in congenital adrenal hyperplasia. Journal of Clinical Endocrinology and Metabolism, 102(6), 1797-1806. https://doi.org/10.1210/jc.2016-2855

Fleseriu, M., & Karavitaki, N. (2016). Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline. The Journal of clinical endocrinology and metabolism, 101(11), 3888-3921. https://doi.org/10.1210/jc.2016-2118

Nieto, H., & Boelaert, K. (2016). Thyroid stimulating hormone in thyroid cancer: does it matter? Endocrine-related cancer, 23(11), [ERC-16-0328]. https://doi.org/10.1530/ERC-16-0328

Karavitaki, N. (2016). Audit on isolated pituitary stalk lesions/thickening in a tertiary hospital: Comprehensive guidelines needed. Poster session presented at Society for Endocrinology BES 2016, Brighton, United Kingdom. https://doi.org/10.1530/endoabs.44.P83

Essig, G. F., Porter, K., Schneider, D., Arpaia, D., Lindsey, S. C., Busonero, G., Fineberg, D., Fruci, B., Boelaert, K., Smit, J. W., Meijer, J. A. A., Duntas, L. H., Sharma, N., Costante, G., Filetti, S., Sippel, R. S., Biondi, B., Topliss, D. J., Pacini, F., ... Kloos, R. T. (2016). Multifocality in Sporadic Medullary Thyroid Carcinoma: An International Multicenter Study. Thyroid, 26(11), 1563-1572. https://doi.org/10.1089/thy.2016.0255

Arlt, W., & Clinical Committee, S. F. E. (2016). Society for Endocrinology Endocrine Emergency Guidance: Emergency management of acute adrenal insufficiency (adrenal crisis) in adult patients. Endocrine Connections, 5(5), G1-G3. https://doi.org/10.1530/EC-16-0054

Boelaert, K. (2016). WOMEN IN CANCER PROFILE: From bedside to bench and back: my journey in thyroid disease. Endocrine-related cancer, 23(11), 9-13. https://doi.org/10.1530/ERC-16-0396

Sbardella, E., & Karavitaki, N. (2016). A macroprolactinoma becoming resistant to cabergoline and developing atypical pathology. Journal of Clinical and Translational Endocrinology: Case Reports, [16-0038]. https://doi.org/10.1530/EDM-16-0038

O'reilly, M., Reulen, R., Gupta, S., Thompson, C., Dineen, R., Goulden, E., Bugg, G., Pearce, H., Toogood, A., Gittoes, N., Mitchell, R., Thompson, C., & Ayuk, J. (2016). ACTH and gonadotrophin deficiency predict mortality in patients treated for nonfunctioning pituitary adenoma (NFPA): long-term follow-up of 519 patients in two large European centres. Clinical Endocrinology, 85(5), 748–756. https://doi.org/10.1111/cen.13141

Walsh, J., Gittoes, N., & Selby, P. (2016). Emergency management of acute hypercalcaemia in adult patients. Endocrine Connections, 5, G9-G11. https://doi.org/10.1530/EC-16-0055

Johnston, N., Mitchell, R., Haythorne, E., Pessoa, M. P., Semplici, F., Ferrer, J., Piemonti, L., Marchetti, P., Bugliani, M., Bosco, D., Berishvili, E., Duncanson, P., Watkinson, M., Broichhagen, J., Trauner, D., Rutter, G., & Hodson, D. (2016). Beta cell hubs dictate pancreatic islet responses to glucose. Cell Metabolism, 24(3), 389-401. https://doi.org/10.1016/j.cmet.2016.06.020

Wakeling, E., Brioude, F., Lokulo-Sodipe, O., O'Connell, S., Salem, J., Bilek, J., Canton, A., Chrzanowska, K., Davies, J., Dias, R., Dubern, B., Elbracht, M., Giabicani, E., Grimberg, A., Groenskov, K., Hokken-Koelega, A., Jorge, A., Kagami, M., Linglart, A., ... Netchine, I. (2016). Diagnosis and management of Silver–Russell syndrome: first international consensus statement. Nature Reviews Endocrinology. https://doi.org/10.1038/nrendo.2016.138

Chun, R., Hernandez, I., Pereira, R., Swinkles, L., Huijs, T., Zhou, R., Liu, N., Shieh, A., Guemes, M., Mallya, S., Adams, J., & Hewison, M. (2016). Differential responses to vitamin D2 and vitamin d3 are associated with variations in free 25-hydroxyvitamin D. Endocrinology, 157(9), 3420-3430. https://doi.org/10.1210/en.2016-1139

Tampourlou, M., Karavitaki, N., Trifanescu, R., Paluzzi, A., & Ahmed, S. K. (2016). Therapy Of Endocrine Disease: Surgery In Microprolactinomas: Effectiveness And Risks Based On Contemporary Literature. European Journal of Endocrinology, 175(3), R89-96. https://doi.org/10.1530/EJE-16-0087

Larner, D., Morgan, S., Gathercole, L., Doig, C., Guest, P., Weston, C., Hazeldine, J., Tomlinson, J., Stewart, P., & Lavery, G. (2016). Male 11β-HSD1 knockout mice fed trans-fats and fructose are not protected from metabolic syndrome or non-alcoholic fatty liver disease. Endocrinology, 157(9). https://doi.org/10.1210/en.2016-1357

Chan, K. X., Mabbitt, P., Phua, S. Y., Mueller, J. W., Nisar, N., Gigolashvilli, T., Stroeher, E., Grassl, J., Arlt, W., Estavillo, G., Jackson, C., & Pogson, B. (2016). Sensing and signaling of oxidative stress in chloroplasts by inactivation of the SAL1 phosphoadenosine phosphatase. National Academy of Sciences. Proceedings, 113(31), E4567-E4576. https://doi.org/10.1073/pnas.1604936113

Fassnacht, M., Arlt, W., Bancos, I., Dralle, H., Newell-Price, J., Sahdev, A., Tabarin, A., Terzolo, M., Tsagarakis, S., & Dekkers, O. (2016). Management of adrenal incidentalomas - a European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors. European Journal of Endocrinology, 175. https://doi.org/10.1530/EJE-16-0467

Dinnes, J., Bancos, I., Ferrante di Ruffano, L., Chortis, V., Davenport, C., Bayliss, S., Sahdev, A., Guest, P., Fassnacht, M., Deeks, J., & Arlt, W. (2016). Management of endocrine disease: Imaging for the diagnosis of malignancy in incidentally discovered adrenal masses: a systematic review and meta-analysis . European Journal of Endocrinology, 175, R51-R64. https://doi.org/10.1530/EJE-16-0461

Bancos, I., Tamhane, S., Shah, M., Delivanis, D., Alahdab, F., Arlt, W., Fassnacht, M., & Murad, M. H. (2016). The diagnostic performance of adrenal biopsy: a systematic review and meta-analysis. European Journal of Endocrinology, 175, R65-R80. https://doi.org/10.1530/EJE-16-0297

Sanderson, J., James, M. M-S., Stevens, J., Goka, E., Wong, R., Campbell, F., Selby, P., Gittoes, N., & Davis, S. (2016). Clinical effectiveness of bisphosphonates for the prevention of fragility fractures: a systematic review and network meta-analysis. Bone, 89, 52-58. https://doi.org/10.1016/j.bone.2016.05.013

Frank, J., Yushchenko, D., Hodson, D., Lipstein, N., Nagpal, J., Rutter, G., Rhee, J-S., Gottschalk, A., Brose, N., Schultz, C., & Trauner, D. (2016). Photoswitchable diacylglycerols enable optical control of protein kinase C. Nature Chemical Biology, 12, 755-762. https://doi.org/10.1038/nchembio.2141

Clayton, R., Jones, P., Reulen, R., Stewart, P., Hassan-Smith, Z., Ntali, G., Karavitaki, N., Dekkers, O., Pereira, A., Bolland, M., Holdaway, I., & Lindholm, J. (2016). Mortality in patients with Cushing's disease more than 10 years after remission: a multicentre, multinational, retrospective cohort study. The Lancet Diabetes and Endocrinology, 4(7), 569-576. https://doi.org/10.1016/S2213-8587(16)30005-5

El-Gamal, M., Semreen, M., Foster, P., & Potter, B. (2016). Design, synthesis, and biological evaluation of new arylamide derivatives possessing sulfonate or sulfamate moieties as steroid sulfatase enzyme inhibitors. Bioorganic & Medicinal Chemistry, 24(12). https://doi.org/10.1016/j.bmc.2016.04.040

Idkowiak, J., Taylor, A. E., Subtil, S., O'neil, D. M., Vijzelaar, R., Dias, R. P., Amin, R., Barrett, T. G., Shackleton, C. H. L., Kirk, J. M. W., Moss, C., & Arlt, W. (2016). Steroid sulfatase sulfatase deficiency and androgen activation before and after puberty. Journal of Clinical Endocrinology and Metabolism, 101(6), 2545-53. https://doi.org/10.1210/jc.2015-4101

Morgan, S., Hassan-Smith, Z., Doig, C., Sherlock, M., Stewart, P., & Lavery, G. (2016). Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism. Journal of Endocrinology, 229(3), 277-286. https://doi.org/10.1530/JOE-16-0011

Aojula, A., Botfield, H., McAllister, J. P., Gonzalez, A., Abdullah, O., Logan, A., & Sinclair, A. (2016). Diffusion tensor imaging with direct cytopathological validation: characterisation of decorin treatment in experimental juvenile communicating hydrocephalus. Fluids and barriers of the CNS, 13, [9]. https://doi.org/10.1186/s12987-016-0033-2

Ferreira, V., Marcelino, M., Piechnik, S., Marini, C., Karamitsos, T., Ntusi, N., Francis, J., Robson, M., Arnold, R., Mihai, R., Thomas, J., Herincs, M., Hassan-Smith, Z., Greiser, A., Arlt, W., Korbonits, M., Karavitaki, N., Grossman, A., Wass, J., & Neubauer, S. (2016). Pheochromocytoma Is characterized by catecholamine-mediated myocarditis, focal and diffuse myocardial fibrosis, and myocardial dysfunction. Journal of the American College of Cardiology, 67(20), 2364–2374. https://doi.org/10.1016/j.jacc.2016.03.543

Shipman, K., Stammers, J., Doyle, A., & Gittoes, N. (2016). Delivering a quality assured fracture liaison service in a UK teaching hospital – is it achievable? Osteoporosis International. https://doi.org/10.1007/s00198-016-3639-y

Rahman, H-U., Hofland, J., & Foster, P. (2016). In Touch with your Feminine Side: How Oestrogen Metabolism Impacts Prostate Cancer. Endocrine-related cancer. https://doi.org/10.1530/ERC-16-0118

Gathercole, L. L., Hazlehurst, J. M., Armstrong, M. J., Crowley, R., Boocock, S., O'Reilly, M. W., Round, M., Brown, R., Bolton, S., Cramb, R., Newsome, P., Semple, R. K., Paisey, R., Tomlinson, J. W., & Geberhiwot, T. (2016). Advanced non-alcoholic fatty liver disease and adipose tissue fibrosis in patients with Alström syndrome. Liver International. https://doi.org/10.1111/liv.13163

Broichhagen, J., Johnston, N. R., Von Ohlen, Y., Meyer-berg, H., Jones, B. J., Bloom, S. R., Rutter, G. A., Trauner, D., & Hodson, D. J. (2016). Allosteric optical control of a class B G-protein-coupled receptor. Angewandte Chemie (International Edition) , 55(19), 5865–5868. https://doi.org/10.1002/anie.201600957

Kempegowda, P., O'Reilly, M. W., Hassan-Smith, Z., Storbeck, K-H., Taylor, A. E., & Arlt, W. (2016). Impaired DHEA sulfation defines androgen excess in women with polycystic ovarian syndrome (PCOS). Endocrine Abstracts. https://doi.org/10.1530/endoabs.41.GP184

Arlt, W., Torchen, L., Idkowiak, J., Fogel, N., O'Neil, D., Shackleton, C., & Dunaif, A. (2016). Evidence for Increased 5α-Reductase During Early Childhood in Daughters of Women with Polycystic Ovary Syndrome. Journal of Clinical Endocrinology and Metabolism, 101(5), 2069-2075. https://doi.org/10.1210/jc.2015-3926#sthash.9Wp6MrQ4.dpuf

Osterstock, G., Mitutsova, V., Barre, A., Granier, M., Fontanaud, P., Chazalon, M., Carmignac, D., Robinson, I., Low, M., Plesnila, N., Hodson, D., Mollard, P., & Mery, P-F. (2016). Somatostatin triggers rhythmic electrical firing in hypothalamic GHRH neurons. Scientific Reports, 6, [24394 ]. https://doi.org/10.1038/srep24394

Crowley, R. K., & Gittoes, N. J. (2016). Elevated PTH with normal serum calcium level: a structured approach. Clinical Endocrinology. https://doi.org/10.1111/cen.13056

Amin, A. M., Wharton, H., Clarke, M., Syed, A., Dodson, P., & Tahrani, A. A. (2016). The impact of bariatric surgery on retinopathy in patients with type 2 diabetes: A retrospective cohort study. Surgery for Obesity and Related Diseases, 12(3), 606-612. https://doi.org/10.1016/j.soard.2015.08.508

Griffin, A., Parajes, S., Weger, M., Zaucker, A., Taylor, A. E., O'Neil, D. M., Müller, F., & Krone, N. (2016). Ferredoxin 1b (Fdx1b) is the essential mitochondrial redox partner for cortisol biosynthesis in zebrafish. Endocrinology, 157(3). https://doi.org/10.1210/en.2015-1480

Amin, A. M., Wharton, H., Clarke, M., Syed, A., Dodson, P., & Tahrani, A. A. (2016). The impact of bariatric surgery on retinopathy in patients with type 2 diabetes: a retrospective cohort study. Surgery for Obesity and Related Diseases, 12(3), 606-612. https://doi.org/10.1016/j.soard.2015.08.508

Srikanth, P., Chun, R. F., Hewison, M., Adams, J. S., Bouillon, R., Vanderschueren, D., Lane, N., Cawthon, P. M., Dam, T., Barrett-Connor, E., Daniels, L. B., Shikany, J. M., Stefanick, M. L., Cauley, J. A., Orwoll, E. S., Nielson, C. M., & Osteoporotic Fractures in Men (MrOS) Study Research Group (2016). Associations of total and free 25OHD and 1,25(OH)2D with serum markers of inflammation in older men. Osteoporosis International. https://doi.org/10.1007/s00198-016-3537-3

Bornstein, S. R., Allolio, B., Arlt, W., Barthel, A., Don-Wauchope, A., Hammer, G. D., Husebye, E. S., Merke, D. P., Murad, M. H., Stratakis, C. A., & Torpy, D. J. (2016). Diagnosis and treatment of primary adrenal insufficiency: an endocrine society clinical practice guideline. The Journal of clinical endocrinology and metabolism, 101(2), 364-89. https://doi.org/10.1210/jc.2015-1710

Juarez, M., McGettrick, H. M., Scheel-Toellner, D., Yeo, L., Spengler, J., de Paz, B., Hardy, R., Cooper, M., Raza, K., Buckley, C. D., & Filer, A. (2016). DKK1 expression by synovial fibroblasts in very early rheumatoid arthritis associates with lymphocyte adhesion in an in vitro flow co-culture system. Arthritis Research & Therapy, 18(1), [14]. https://doi.org/10.1186/s13075-016-0915-3

Vitlic, A., Lord, J. M., Taylor, A. E., Arlt, W., Bartlett, D. B., Rossi, A., Arora-Duggal, N., Welham, A., Heald, M., Oliver, C., Carroll, D., & Phillips, A. C. (2016). Neutrophil function in young and old caregivers. British Journal of Health Psychology, 21(1), 173-189. https://doi.org/10.1111/bjhp.12156

Hazlehurst, J. M., Oprescu, A. I., Nikolaou, N., Di Guida, R., Grinbergs, A. E. K., Davies, N. P., Flintham, R. B., Armstrong, M. J., Taylor, A. E., Hughes, B. A., Yu, J., Hodson, L., Dunn, W. B., & Tomlinson, J. W. (2016). Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man. The Journal of clinical endocrinology and metabolism, 101(1), 103-113. https://doi.org/10.1210/jc.2015-2928

Doig, C. L., Battaglia, S., Khanim, F. L., Bunce, C. M., & Campbell, M. J. (2016). Knockdown of AKR1C3 exposes a potential epigenetic susceptibility in prostate cancer cells. The Journal of Steroid Biochemistry and Molecular Biology, 155 ( Part A), 47-55. https://doi.org/10.1016/j.jsbmb.2015.09.037

Karavitaki, N. (2016). Craniopharyngiomas: Natural History and Clinical Presentation. In A. Lania, A. Spada, & G. Lasio (Eds.), Diagnosis and Management of Craniopharyngiomas Springer. https://doi.org/10.1007/978-3-319-22297-4_1

Sarkar, S., Hewison, M., Studzinski, G. P., Li, Y. C., & Kalia, V. (2016). Role of vitamin D in cytotoxic T lymphocyte immunity to pathogens and cancer. Critical Reviews in Clinical Laboratory Sciences, 1-14. https://doi.org/10.3109/10408363.2015.1094443

Büttler, R. M., Martens, F., Fanelli, F., Pham, H. T., Kushnir, M. M., Janssen, M. J. W., Owen, L., Taylor, A. E., Soeborg, T., Blankenstein, M. A., & Heijboer, A. C. (2015). Comparison of 7 Published LC-MS/MS Methods for the Simultaneous Measurement of Testosterone, Androstenedione, and Dehydroepiandrosterone in Serum. Clinical Chemistry, 61(12), 1475-83. https://doi.org/10.1373/clinchem.2015.242859

Shaw, G. L., Whitaker, H., Corcoran, M., Dunning, M. J., Luxton, H., Kay, J., Massie, C. E., Miller, J. L., Lamb, A. D., Ross-Adams, H., Russell, R., Nelson, A. W., Eldridge, M. D., Lynch, A. G., Ramos-Montoya, A., Mills, I. G., Taylor, A. E., Arlt, W., Shah, N., ... Neal, D. E. (2015). The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer. European urology. https://doi.org/10.1016/j.eururo.2015.10.042

Woods, C. P., Argese, N., Chapman, M., Boot, C., Webster, R., Dabhi, V., Grossman, A. B., Toogood, A. A., Arlt, W., Stewart, P. M., Crowley, R. K., & Tomlinson, J. W. (2015). Adrenal suppression in patients taking inhaled glucocorticoids is highly prevalent and management can be guided by morning cortisol. European Journal of Endocrinology, 173(5), 633-42. https://doi.org/10.1530/EJE-15-0608

Mooij, C. F., Parajes, S., Rose, I. T., Taylor, A. E., Bayraktaroglu, T., Wass, J. A. H., Connell, J. M. C., Ray, D. W., Arlt, W., & Krone, N. (2015). Characterization of the molecular genetic pathology in patients with 11β-hydroxylase deficiency. Clinical Endocrinology, 83(5), 629-635. https://doi.org/10.1111/cen.12834

Read, M., Fong, J., Imruetaicharoenchoke, W., Modasia, B., Lewy, G., Ryan, G., Sharma, N., Smith, V., Watkinson, J., Boelaert, K., & McCabe, C. (2015). Distinct p53 response profiles in transgenic mouse models of thyroid-specific PBF and PTTG expression. Endocrine Abstracts, 38, [P149]. https://doi.org/10.1530/endoabs.38.P149

Read, M., Smith, J., Smith, V., Bosseboeuf, E., Wake, N., Watkinson, J., Wallis, Y., Maher, E., McCabe, C., & Woodward, E. (2015). Functional consequences of germline mutations in a novel non-RET medullary thyroid cancer susceptibility gene. Endocrine Abstracts, 38, [OC5.1]. https://doi.org/10.1530/endoabs.38.OC5.1

Sherlock, M., Behan, L. A., Hannon, M. J., Alonso, A. A., Thompson, C. J., Murray, R. D., Crabtree, N., Hughes, B. A., Arlt, W., Agha, A., Toogood, A. A., & Stewart, P. M. (2015). The modulation of corticosteroid metabolism by hydrocortisone therapy in patients with hypopituitarism increases tissue glucocorticoid exposure. European Journal of Endocrinology, 173(5), 583-93. https://doi.org/10.1530/EJE-15-0490

Dar, S., Tahrani, A. A., & Piya, M. K. (2015). The role of GLP-1 receptor agonists as weight loss agents in patients with and without type 2 diabetes. Practical Diabetes, 32(8), 297-300b. https://doi.org/10.1002/pdi.1978

Hodson, L., Banerjee, R., Rial, B., Arlt, W., Adiels, M., Boren, J., Marinou, K., Fisher, C., Mostad, I. L., Stratton, I. M., Barrett, P. H. R., Chan, D. C., Watts, G. F., Harnden, K., Karpe, F., & Fielding, B. A. (2015). Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women. Journal of the American Heart Association, 4(10), [e002258]. https://doi.org/10.1161/JAHA.115.002258

Kempegowda, P., O'Reilly, M. W., Crabtree, N. J., Taylor, A. E., Hughes, B. A., Tomlinson, J. W., & Arlt, W. (2015). Visceral fat drives 5[alpha]-reductase activity independent of BMI in women with polycystic ovarian syndrome. Endocrine Abstracts. https://doi.org/10.1530/endoabs.38.P356

O'Reilly, M., Kempegowda, P., Botfield, H., Ali, F., Taylor, A., Hughes, B., Tomlinson, J., Arlt, W., & Sinclair, A. (2015). Women with idiopathic intracranial hypertension have a distinct andro-metabolic signature compared to polycystic ovary syndrome and simple obesity. Endocrine Abstracts. https://doi.org/10.1530/endoabs.38.P193

Mueller, J. W., Gilligan, L. C., Idkowiak, J., Arlt, W., & Foster, P. A. (2015). The Regulation of Steroid Action by Sulfation and Desulfation. Endocrine Reviews, 36(5), 526-563. https://doi.org/10.1210/er.2015-1036

Stengel, C., Newman, S. P., Leese, M. P., Thomas, M. P., Potter, B. V. L., Reed, M. J., Purohit, A., & Foster, P. A. (2015). The in vitro and in vivo activity of the microtubule disruptor STX140 Is mediated by Hif-1 alpha and CAIX expression. Anticancer research, 35(10), 5249-5261. https://ar.iiarjournals.org/content/35/10/5249

Daniel, E., Aylwin, S., Mustafa, O., Ball, S., Munir, A., Boelaert, K., Chortis, V., Cuthbertson, D. J., Daousi, C., Rajeev, S. P., Davis, J., Cheer, K., Drake, W., Gunganah, K., Grossman, A., Gurnell, M., Powlson, A. S., Karavitaki, N., Huguet, I., ... Newell-Price, J. (2015). Effectiveness of metyrapone in treating Cushing's Syndrome: a retrospective multicenter study in 195 patients. The Journal of clinical endocrinology and metabolism, 100(11), [jc20152616]. https://doi.org/10.1210/jc.2015-2616

Ahmed, S. F., Achermann, J. C., Arlt, W., Balen, A., Conway, G., Edwards, Z., Elford, S., Hughes, I. A., Izatt, L., Krone, N., Miles, H., O'Toole, S., Perry, L., Sanders, C., Simmonds, M., Watt, A., & Willis, D. (2015). Society for Endocrinology UK guidance on the initial evaluation of an infant or an adolescent with a suspected disorder of sex development (Revised 2015). Clinical Endocrinology. https://doi.org/10.1111/cen.12857

Taylor, A. E., Keevil, B., & Huhtaniemi, I. T. (2015). Mass spectrometry and immunoassay: how to measure steroid hormones today and tomorrow. European Journal of Endocrinology, 173(2), D1-12. https://doi.org/10.1530/EJE-15-0338

Capatina, C., Paluzzi, A., Mitchell, R., & Karavitaki, N. (2015). Diabetes insipidus after traumatic brain injury. Journal of Clinical Medicine, 4(7), 1448-62. https://doi.org/10.3390/jcm4071448

Hassan-Smith, Z. K., Morgan, S. A., Sherlock, M., Hughes, B., Taylor, A. E., Lavery, G. G., Tomlinson, J. W., & Stewart, P. M. (2015). Gender-specific differences in skeletal muscle 11β-HSD1 expression across healthy aging. The Journal of clinical endocrinology and metabolism, 100(7), 2673-2681. https://doi.org/10.1210/jc.2015-1516

Mooij, C. F., Parajes, S., Pijnenburg-Kleizen, K. J., Arlt, W., Krone, N., & Claahsen-van der Grinten, H. L. (2015). Influence of 17-Hydroxyprogesterone, Progesterone and Sex Steroids on Mineralocorticoid Receptor Transactivation in Congenital Adrenal Hyperplasia. Hormone research in paediatrics, 83(6), 414-421. https://doi.org/10.1159/000374112

Ho, S. C., Clayton, P., Vasudevan, P., Greening, J., Wardhaugh, B., Shaw, N., Kelnar, C., Kirk, J., & Högler, W. (2015). Recombinant Human Growth Hormone Therapy in Children with Chromosome 15q26 Deletion. Hormone Research in Paediatrics, 83(6), 424-430. https://doi.org/10.1159/000380949