In women with pregnancy hypertension (P), what is the effect of a treatment strategy with nifedipine (I) versus labetalol (C) on severe maternal hypertension (O) and a composite of fetal or neonatal death, or neonatal unit admissions (O)?
A prospective, late phase, pragmatic, parallel group, open-label, multicentre, two-arm randomised controlled trial. Women who decline randomisation or are unable to be randomised (due to contraindications to either labetalol or nifedipine or women taking both drugs and not able to be randomised to a single drug) will be offered participation in an observational study, involving data collection only.