Design:
Prospective observational cohort study aligned with the Giant PANDA study.
Objectives:
1) To determine short-term BP response of nifedipine versus labetalol.
2) To explore the association between short-term BP response and long-term BP control (Giant PANDA primary outcome).
3) To assess whether maternal characteristics, disease markers or drug metabolites provide mechanistic insight into differing responses to antihypertensive agents between individuals.