108 out of 172 (63%) people in VB group had a major amputation or died, compared to 92 out of 173 (53%) people in BET group. This means that a VB first strategy was associated with an increased risk of major amputation or death compared with a BET first strategy.
This difference was mainly due to fewer deaths in the BET group. Cardiovascular and respiratory diseases were the most common causes of death in both groups. However, there were no single common causes of death in either group to explain the differences in number of deaths between the two groups.
Amputation outcomes were similar between the two groups.
Our findings suggest a greater role for best endovascular treatment first strategy in the management of patients with CLTI who require an infra-popliteal revascularisation to restore limb perfusion.
View our presentation at the Charing Cross International Symposium for more information,
You can also read the full results in The Lancet paper : Bradbury, Andrew W et al (2023) A vein bypass first versus a best endovascular treatment first revascularisation strategy for patients with chronic limb threatening ischaemia who required an infra-inguinal revasularisation procedure to restore limb perfusion (BASIL-2): an open-label, randomised, multicentre, phase 3 trial in The Lancet (online 25 April 2023)