Recent publications
Article
Wallis, NJ, McClellan, A, Mörseburg, A, Kentistou, KA, Jamaluddin, A, Dowsett, GKC, Schofield, E, Morros-Nuevo, A, Saeed, S, Lam, BYH, Sumanasekera, NT, Chan, J, Kumar, SS, Zhang, RM, Wainwright, JF, Dittmann, M, Lakatos, G, Rainbow, K, Withers, D, Bounds, R, Ma, M, German, AJ, Ladlow, J, Sargan, D, Froguel, P, Farooqi, IS, Ong, KK, Yeo, GSH, Tadross, JA, Perry, JRB, Gorvin, CM & Raffan, E 2025, 'Canine genome-wide association study identifies DENND1B as an obesity gene in dogs and humans', Science (New York, N.Y.). https://doi.org/10.1126/science.ads2145
Wyatt, RA, Jamaluddin, A, Mistry, V, Quinn, C & Gorvin, C 2025, 'Obesity-associated MRAP2 variants impair multiple MC4R-mediated signaling pathways', Human Molecular Genetics. https://doi.org/10.1093/hmg/ddaf005
Jamaluddin, A, Chuang, C, Williams, ET, Siow, A, Yang, SH, Harris, PWR, Petersen, JSSM, Bower, RL, Chand, S, Brimble, MA, Walker, CS, Hay, DL & Loomes, KM 2022, 'Lipidated calcitonin gene-related peptide (CGRP) peptide antagonists retain CGRP receptor activity and attenuate CGRP action in vivo', Frontiers in Pharmacology, vol. 13, 832589. https://doi.org/10.3389/fphar.2022.832589
Garelja, ML, Bower, RL, Brimble, MA, Chand, S, Harris, PWR, Jamaluddin, MA, Petersen, J, Siow, A, Walker, CS & Hay, DL 2022, 'Pharmacological characterisation of mouse calcitonin and calcitonin receptor‐like receptors reveals differences compared to human receptors', British Journal of Pharmacology, vol. 179, no. 3, pp. 416-434. https://doi.org/10.1111/bph.15628
Jamaluddin, A 2020, 'Identification of Small-Molecule Positive Modulators of Calcitonin-like Receptor-Based Receptors', ACS Pharmacology & Translational Science. https://doi.org/10.1021/acsptsci.9b00108
Jamaluddin, A 2018, 'Solid‐Phase Thiol–Ene Lipidation of Peptides for the Synthesis of a Potent CGRP Receptor Antagonist', Angewandte Chemie (International Edition) . https://doi.org/10.1002/anie.201805208
Jamaluddin, A 2015, 'A second trigeminal
CGRP
receptor: function and expression of the
AMY
1
receptor', Annals of Clinical and Translational Neurology. https://doi.org/10.1002/acn3.197
Jamaluddin, A 2015, 'Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor', Molecular Cell. https://doi.org/10.1016/j.molcel.2015.04.018
Chapter
Jamaluddin, A 2024, Bioluminescence Resonance Energy Transfer (BRET) Assay to Measure Gq Recruitment to the Ghrelin Receptor. in CM Gorvin (ed.), Calcium Signaling: Methods and Protocols. 1 edn, Methods in Molecular Biology, Humana Press, pp. 57-69. https://doi.org/10.1007/978-1-0716-4164-4_5
Jamaluddin, A 2024, Quantifying Gq Signaling Using the IP1 Homogenous Time-Resolved Fluorescence (HTRF) Assay. in CM Gorvin (ed.), Calcium Signaling: Methods and Protocols. 1 edn, Methods in Molecular Biology, Humana Press, pp. 23-32. https://doi.org/10.1007/978-1-0716-4164-4_2
Doctoral Thesis
Jamaluddin, A 2020, 'Development of CGRP receptor peptide antagonists as potential therapeutics', ???thesis.qualification.phd???, University of Auckland. <http://hdl.handle.net/2292/53025>
Master's Thesis
Jamaluddin, A 2015, 'Identifying novel small molecule ligands for the AM1 receptor', University of Auckland. <http://hdl.handle.net/2292/26617>
Preprint
Wyatt, RA, Jamaluddin, A, Mistry, V, Quinn, C & Gorvin, CM 2024 'Obesity-associated MRAP2 variants impair multiple MC4R-mediated signaling pathways' bioRxiv. https://doi.org/10.1101/2024.11.19.622403
Jamaluddin, A, Wyatt, RA, Lee, J, Dowsett, GKC, Tadross, JA, Broichhagen, J, Yeo, GSH, Levitz, J & Gorvin, CM 2024 'The MRAP2 accessory protein directly interacts with melanocortin-3 receptor to enhance signaling' bioRxiv. https://doi.org/10.1101/2024.11.06.622243
Review article
Jamaluddin, A & Gorvin, CM 2023, 'RISING STARS: Targeting G protein-coupled receptors to regulate energy homeostasis', Journal of Molecular Endocrinology, vol. 70, no. 4, e230014. https://doi.org/10.1530/JME-23-0014
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