Professor Janesh K. Gupta MSc, MD, FRCOG

Professor Janesh K. Gupta

Department of Metabolism and Systems Science
Honorary Clinical Professor
Honorary Consultant at Birmingham Women’s and Children’s NHS Foundation Trust

Contact details

Telephone
+44 (0)121 472 1377 extension 5410
Email
j.k.gupta@bham.ac.uk
View my research portal
Address
Birmingham Women's and Children’s Foundation NHS Trust
Mindelsohn Way
Edgbaston
Birmingham
B15 2TG

Janesh Gupta is an Honorary Clinical Professor in the Metabolism and Systems Science working as an Honorary Consultant at Birmingham Women’s and Children’s NHS Foundation Trust.

Janesh has published over 175 research papers in scientific journals, book chapters, reviews and books and over 100 lectures and presentations to learned societies in the fields of fetal medicine, benign gynaecology (including abnormal uterine bleeding, fibroids, endometriosis, endometrial hyperplasia), minimal access surgery, induction of labour and abortion. He has received grants from WellBeing of Women, Department of Health National Institute for Health Research (Health Technology Assessment), Medical Research Council and various industry partners.

For his research excellence, Janesh was honoured in 2019, as a University of Birmingham 'Birmingham Hero'. He is the Editor-in-Chief for the European Journal of Obstetrics and Gynecology and Reproductive Biology and wa previously on the Editorial Board for Surgical Endoscopy and Gynaecological Surgery.

Birmingham Heroes campaign image showing four academics. Professor Janesh Gupta is one of them

Qualifications

  • 2004   FRCOG, Fellow of Royal College of Obstetricians and Gynaecologists
  • 1998   MD, University of Leeds
  • 1998   MRCOG, Royal College of Obstetricians and Gynaecologists
  • 1991   MSc by Research Thesis, Obstetrics and Gynaecology, University of Leeds
  • 1987   MBChB, University of Leeds

Biography

Janesh has been a Consultant Obstetrician and Gynaecologist since 1995, at 31 years of age, Ninewells Hospital & Medical School, Dundee, Scotland. He is a practising obstetrician and gynaecologist and has a regular labour ward session and carries out on-call duties as a senior obstetrician and gynaecologist at Birmingham Women’s Hospital.

His research experience has led him to publish Cochrane reviews and systematic reviews of diagnostic tests for abnormal uterine bleeding, preterm labour and pre-eclampsia. He has had several grants from WellBeing of Women, National Health Institute for Research (Health Technology Assessment), Medical Research Council and various industry partners evaluating chronic pelvic pain (LUNA trial published in JAMA), heavy menstrual bleeding (ECLIPSE trial, NIHR £1.6 million published in NEJM), endometriosis (PRE-EMPT trial) and labour trials: BUMPES trial (NIHR £2.5 million) and SOLVE trial. He has also had basic science projects in endometriosis and endometrial hyperplasia. 

Listen to Professor Gupta discuss 'Heavy Period Treatment Expected to Change Clinical Practice'. You can also view a transcript of the podcast.

Teaching

Postgraduate supervision

Professor Gupta is interested in supervising doctoral research students in the following areas:

  • Abnormal uterine bleeding
  • Endometriosis
  • Endometrial hyperplasia
  • Ambulatory hysteroscopy care
  • Abortion
  • Enhanced recovery

Research

Clinical trials in collaboration with Birmingham Clinical Trials Unit (BCTU), systematic reviews, endometriosis, induction of labour, abortion care, and endometrial hyperplasia – biomarkers for the prognostic and diagnostic evaluation in hyperplasia.

Janesh has just completed the largest randomised controlled trial in the world comparing Dilapan (osmotic dilator) versus dinoprostone (SOLVE trial) in induction of labour, recruiting 570 patients. 

Other activities

Janesh’s clinical and research interests have been called upon in the giving expert evidence in clinical negligence and criminal cases for the Metropolitan Police, Lincolnshire Police and many other police forces for series and serious sexual offences, sexual assault, deaths of women and babies. He has appeared several times in court to give evidence and given expert evidence at the Old Bailey, London on two occasions. 

Janesh currently organises and teaches on a twice a year basis the Part II and Part III MRCOG course in Bangalore, India.

Publications

Recent publications

Article

UKARCOG Working Group Authors 2024, 'Diagnosis and management of endometrial hyperplasia: A UK national audit of adherence to national guidance 2012–2020', PLoS Medicine, vol. 21, no. 2, e1004346. https://doi.org/10.1371/journal.pmed.1004346

Lancaster, T, Tabrizi, MEA, Repici, M, Gupta, J & Gross, SR 2023, 'An Extracellular/Membrane-Bound S100P Pool Regulates Motility and Invasion of Human Extravillous Trophoblast Lines and Primary Cells', Biomolecules, vol. 13, no. 8, 1231. https://doi.org/10.3390/biom13081231

Gupta, J, Maher, A, Stubbs, C, Brocklehurst, P, Daniels, J & Hardy, P 2022, 'A randomized trial of synthetic osmotic cervical dilator for induction of labor vs dinoprostone vaginal insert', American Journal of Obstetrics & Gynecology Maternal Fetal Medicine , vol. 4, no. 4, 100628. https://doi.org/10.1016/j.ajogmf.2022.100628

Ganguly, A, Tamblyn, JA, Shattock, A, Joseph, A, Larner, DP, Jenkinson, C, Gupta, J, Gross, SR & Hewison, M 2021, 'Trophoblast uptake of DBP regulates intracellular actin and promotes matrix invasion', Journal of Endocrinology, vol. 249, no. 1, pp. 43-55. https://doi.org/10.1530/JOE-20-0626

Chodankar, R, Gupta, J, Gdovinova, D, Bovo, MJ, Hanacek, J, Kan, N, Roizin, J & Tyutyunnik, V 2018, 'Synthetic osmotic dilators for cervical preparation prior to abortion-An international multicentre observational study', European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 228, pp. 249-254. https://doi.org/10.1016/j.ejogrb.2018.07.013

Janjua, A, Smith, P, Chu, J, Raut, N, Malick, S, Gallos, ID, Singh, R, Irani, S, Gupta, J, Parle, J & Clark, TJ 2017, 'The effectiveness of gynaecology teaching associates in teaching pelvic examination to medical students: a randomised controlled trial', European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 210, pp. 58-63. https://doi.org/10.1016/j.ejogrb.2016.10.006

Antoun, L, Smith, P, Gupta, J & Clark, TJ 2017, 'The feasibility, safety, and effectiveness of hysteroscopic sterilization compared with laparoscopic sterilization', American journal of obstetrics and gynecology. https://doi.org/10.1016/j.ajog.2017.07.011

Ganguly, A, Tamblyn, JA, Finn-Sell, S, Chan, S-Y, Westwood, M, Gupta, J, Kilby, M, Gross, SR & Hewison, M 2017, 'Vitamin D, the placenta and early pregnancy: effects on trophoblast function', Journal of Endocrinology. https://doi.org/10.1530/JOE-17-0491

Daniels, J, Champaneria, R, Shah, L, Gupta, J, Birch, J, Middleton, L & Moss, JG 2016, 'Effectiveness of embolization or sclerotherapy of pelvic veins for reducing chronic pelvic pain: a systematic review', Journal of Vascular and Interventional Radiology, vol. 27, no. 10, pp. 1478-1486.

Champaneria, R, Shah, L, Moss, J, Gupta, JK, Birch, J, Middleton, LJ & Daniels, JP 2016, 'The relationship between pelvic vein incompetence and chronic pelvic pain in women: systematic reviews of diagnosis and treatment effectiveness', Health Technology Assessment, vol. 20, no. 5, pp. 1-108. https://doi.org/10.3310/hta20050

Kai, J, Middleton, L, Daniels, J, Pattison, HM, Tryposkiadis, K & Gupta, J 2016, 'Usual medical treatments or levonorgestrel-IUS for women with heavy menstrual bleeding: long-term randomised pragmatic trial in primary care', British Journal of General Practice , vol. 66, no. 653, pp. e861-e870. https://doi.org/10.3399/bjgp16X687577

Gupta, JK, Daniels, JP, Middleton, LJ, Pattison, HM, Prileszky, G, Roberts, TE, Sanghera, S, Barton, P, Gray, R & Kai, J 2015, 'A randomised controlled trial of effectiveness and cost effectiveness of levonorgestrel-releasing intrauterine system in primary care against standard treatment for menorrhagia: the Eclipse Trial: the ECLIPSE trial', Health Technology Assessment, vol. 19, no. 88, pp. 1-118. https://doi.org/10.3310/hta19880

Zoll, M, Mertes, H & Gupta, J 2015, 'Corporate giants provide fertility benefits: have they got it wrong?', European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 195, pp. A1-A2. https://doi.org/10.1016/j.ejogrb.2015.10.018

Review article

Sundar, S, Balega, J, Crosbie, E, Drake, A, Edmondson, R, Fotopoulou, C, Gallos, I, Ganesan, R, Gupta, J, Johnson, N, Kitson, S, Mackintosh, M, Martin-Hirsch, P, Miles, T, Rafii, S, Reed, N, Rolland, P, Singh, K, Sivalingam, V & Walther, A 2017, 'BGCS uterine cancer guidelines: Recommendations for practice', European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 213, pp. 71-97. https://doi.org/10.1016/j.ejogrb.2017.04.015

Charalampakis, V, Tahrani, AA, Helmy, A, Gupta, JK & Singhal, R 2016, 'Polycystic ovary syndrome and endometrial hyperplasia: an overview of the role of bariatric surgery in female fertility', European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 207, pp. 220-226. https://doi.org/10.1016/j.ejogrb.2016.10.001, https://doi.org/10.1016/j.ejogrb.2016.10.001

View all publications in research portal

Expertise

Maternal health

  • Endometriosis
  • Endometrial hyperplasia
  • Abortion