Recent publications
Article
Grudzinska, F, Faniyi, AA, Belchamber, KBR, Chen, C, Stockley, R, Jasper, A, Parekh, D, Sapey, E, Scott, A & Thickett, DR 2025, 'Hospitalised older adults with community-acquired pneumonia and sepsis have dysregulated neutrophil function but preserved glycolysis', Thorax, vol. 80, no. 2, pp. 97-104. https://doi.org/10.1136/thorax-2024-222215
STRESS-L Collaborators, Thomas, JL, Mcgee, KC, Hossain, A, Perkins, GD, Gordon, AC, Young, D, McAuley, D, Singer, M, Lall, R, Kramaric, T, Lord, JM, Whitehouse, T & Mur, LAJ 2025, 'The effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Randomised Study', Intensive Care Medicine Experimental, vol. 13, no. 1, 9. https://doi.org/10.1186/s40635-024-00708-6
Mahida, RY, Yuan, Z, Kolluri, KK, Scott, A, Parekh, D, Hardy, RS, Matthay, MA, Perkins, GD, Janes, SM & Thickett, DR 2024, '11β hydroxysteroid dehydrogenase type 1 transgenic mesenchymal stem cells attenuate inflammation in models of sepsis', Frontiers in Bioengineering and Biotechnology, vol. 12, 1422761. https://doi.org/10.3389/fbioe.2024.1422761
PHOSP-COVID Collaborative Group, Elneima, O, McAuley, HJC, Leavy, OC, Chalmers, JD, Horsley, A, Ho, L-P, Marks, M, Poinasamy, K, Raman, B, Shikotra, A, Singapuri, A, Sereno, M, Harris, VC, Houchen-Wolloff, L, Saunders, RM, Greening, NJ, Richardson, M, Quint, JK, Briggs, A, Docherty, AB, Kerr, S, Harrison, EM, Lone, NI, Thorpe, M, Heaney, LG, Lewis, KE, Aul, R, Beirne, P, Bolton, CE, Brown, JS, Choudhury, G, Bakerly, ND, Easom, N, Echevarria, C, Fuld, J, Hart, N, Hurst, JR, Jones, MG, Parekh, D, Pfeffer, P, Rahman, NM, Rowland-Jones, SL, Thompson, AR, Jolley, C, Shah, AM, Wootton, DG, Chalder, T, Davies, MJ, De Soyza, A, Geddes, JR, Greenhalf, W, Heller, S, Howard, LS, Jacob, J, Jenkins, RG, Lord, JM, Man, WD-C, McCann, GP, Neubauer, S, Openshaw, PJ, Porter, JC, Rowland, MJ, Scott, JT, Semple, MG, Singh, SJ, Thomas, DC, Toshner, M, Smith, N, Sheikh, A, Brightling, CE, Wain, LV & Evans, RA 2024, 'Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study', International Journal of Epidemiology, vol. 53, no. 1, dyad165. https://doi.org/10.1093/ije/dyad165
Thein, OS, Belchamber, K, Hazeldine, J, Faniyi, A, Grudzinska, F, Hughes, M, Jasper, A, Yip, KP, Crowley, L, Lugg, S, Sapey, E, Parekh, D, Thickett, D & Scott, A 2024, 'Dysfunctional neutrophil response in COVID-19 infection vary by subtype', Clinical Medicine, Journal of the Royal College of Physicians of London, vol. 23, no. 6, pp. 69-70. https://doi.org/10.7861/clinmed.23-6-s69
Jasper, A, Faniyi, A, Davis, L, Grudzinska, F, Halston, R, Hazeldine, J, Parekh, D, Sapey, E, Thickett, D & Scott, A 2024, 'E-cigarette vapor renders neutrophils dysfunctional due to filamentous actin accumulation', Journal of Investigational Allergology and Clinical Immunology, vol. 153, no. 1, pp. 320-329.e8. https://doi.org/10.1016/j.jaci.2023.08.025
Pittaway, H, Grudzinska, F, Livesey, A, Quarton, S, Adiga, A, Dosanjh, D & Parekh, D 2024, 'Management of Non-Ventilated hospital acquired pneumonia', Clinical Infection in Practice, vol. 21, 100350. https://doi.org/10.1016/j.clinpr.2024.100350
Quarton, S, Livesey, A, Jeff, C, Hatton, C, Scott, A, Parekh, D, Thickett, D, McNally, A & Sapey, E 2024, 'Metagenomics in the Diagnosis of Pneumonia: Protocol for a Systematic Review', JMIR Research Protocols, vol. 13, e57334. https://doi.org/10.2196/57334
Harriman, A, Butler, K, Parekh, D & Weblin, J 2024, 'Quality improvement project to improve adherence to lung protective ventilation guidelines', BMJ open quality, vol. 13, no. 2, e002638. https://doi.org/10.1136/bmjoq-2023-002638
Quarton, S, McGee, K, Cumley, N, Behruznia, M, Jeff, C, Belchamber, K, Cox, M, Thickett, D, Scott, A, Parekh, D, McNally, A & Sapey, E 2024, 'Towards personalised anti-microbial and immune approaches to infections in acute care. Can real-time genomic-informed diagnosis of pathogens, and immune-focused therapies improve outcomes for patients? An observational, experimental study protocol', PLoS ONE, vol. 19, no. 3, e0298425. https://doi.org/10.1371/journal.pone.0298425
Chadda, KR, Roberts, SA, Lugg, ST, Faniyi, AA, Faustini, SE, Webster, C, Duffy, JE, Hewison, M, Shields, A, Richter, AG, Parekh, D, Scott, A & Thickett, DR 2024, 'Vitamin D deficiency and duration of COVID-19 symptoms in UK healthcare workers', Frontiers in Medicine, vol. 11, 1494129. https://doi.org/10.3389/fmed.2024.1494129
Letter
Rose, L, Camporota, L, Contreras, A, Couper, K, Hadfield, D, Alleyne, S, Barabas, J, Boex, SM, Connolly, BA, Dark, P, Davies, C, Dawson, A, De Soyza, A, Felton, TW, Guck, J, Hale, D, Hill, MC, Hopkins, PA, Hossain, A, Ji, C, Jin, H, Kandiyali, R, Khan, KA, Kitchen, GB, Krovi, DN, Lall, R, Law, E, Lea, K, Madan, JJ, McGrath, BA, Michael, A, Mills, GH, Mildner, R, Noufaily, A, Parekh, D, Parvin, C, Patel, V, Perkins, G, Rafferty, GF, Shankar-Hari, M, Shyamsunder, M, Steiner, M, Tassie, E, Thirlwall, J, Thompson, M, Watkins, B, Williams, RL, Yeung, J, Zanganeh, M, Starr, K & McAuley, D 2025, 'The COnfederation of REspiratory Critical Care Trials (CoReCCT): a UK research confederation', British Journal of Anaesthesia, vol. 134, no. 2, pp. 566-568. https://doi.org/10.1016/j.bja.2024.10.033
Review article
Quarton, S, Livesey, A, Pittaway, H, Adiga, A, Grudzinska, F, McNally, A, Dosanjh, D, Sapey, E & Parekh, D 2024, 'Clinical challenge of diagnosing non-ventilator hospital-acquired pneumonia and identifying causative pathogens: a narrative review', The Journal of Hospital Infection, vol. 149, pp. 189-200. https://doi.org/10.1016/j.jhin.2024.02.029
Crowley, LE, Stockley, RA, Thickett, DR, Dosanjh, D, Scott, A & Parekh, D 2024, 'Neutrophil dynamics in pulmonary fibrosis: pathophysiological and therapeutic perspectives', European Respiratory Review, vol. 33, no. 174, 240139. https://doi.org/10.1183/16000617.0139-2024
Livesey, A, Quarton, S, Pittaway, H, Adiga, A, Grudzinska, F, Dosanjh, D & Parekh, D 2024, 'Practices to prevent non-ventilator hospital-acquired pneumonia: a narrative review', The Journal of Hospital Infection. https://doi.org/10.1016/j.jhin.2024.03.019
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