Dr Clara Green MBChB MRCP PhD

Department of Inflammation and Ageing
Academic Clinical Lecturer in Respiratory Medicine

Contact details

Email
c.e.green@bham.ac.uk
Twitter
@ClaraEGreen
Address
College of Medical and Dental Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Clara Green is an Academic Clinical Lecturer in Respiratory Medicine. She is interested in Chronic Obstructive Pulmonary Disease (COPD). Her particular interests include the relationship between COPD and lung cancer and the role of the pulmonary endothelium in these conditions.

Qualifications

  • PhD in the understanding of the shared pathogenesis between COPD and lung cancer by means of cell specific genomics, University of Birmingham, 2018
  • Membership of the Royal College of Physicians (MRCP), 2010
  • MBChB (Hons), University of Birmingham, 2007

Biography

Clara completed her primary medical degree at the University of Birmingham and graduated with Honours in 2007. After completing foundation and core medical training she started training as a specialist registrar in general internal and respiratory medicine in 2011. She passed the Specialist Certificate of Respiratory medicine exam in 2013. 

In 2013 Clara joined the Institute of Inflammation and Ageing as a clinical research fellow where she contributed to clinical research in COPD, including alpha-1-antitrypsin deficiency. She also completed her PhD during this time where she explored the role of miRNA and mRNA in the pulmonary endothelium in the pathogenesis of COPD and lung cancer. 

In 2018 she re-joined the institute as an academic clinical lecturer and her primary research interests remain COPD and the role of miRNA and mRNA expression in endothelial function and angiogenesis. 

Clara has presented at multiple national and international meetings and was awarded the Harold Thomas Travelling Fellowship by the Midlands Thoracic Society in 2017. In addition to her research commitments she has also contributed to teaching medical and dental students at the University.

Research

The role of miRNA an mRNA expression in the pulmonary endothelium in the pathogenesis of COPD and lung cancer. 

The effect of genotype on prognosis and pulmonary phenotype in alpha-1-antitrypsin deficiency.

The use of CT densitometry decline in alpha-1-antitrypsin deficiency to determine patient survival.

Research groups and Centres

Birmingham Acute Care Research Group 

Publications

Foley P. Addison CE. Whinney, SB. Patel, KR. Cunningham, D. Frenneaux, M. Leyva, F. Implantable Cardioverter Defibrillator therapy for primary prevention of Sudden Cardiac Death following a myocardial infarction: implications of international guidelines. Pacing and Clinical Electrophysiology. 2009. 32: S1-4 DOI: 10.1111/j.1540-8159.2008.02268.x https://onlinelibrary.wiley.com/doi/full/10.1111/j.1540-8159.2008.02268.x 

Fish, R. Pinney, J. Jain, P.  Addison, C. Jones, C. Jayawardene, S. Booth, J. Howie, AJ. Ghonemy, T. Rajabali, S. Roberts, D. White, L. Khan, S. Morgan, M. Cockwell, P. Hutchison, CA. The Incidence of Major Hemorrhagic Complications After Renal Biopsies in Patients with Monoclonal Gammopathies. Clin J Am Soc Nephrol . 2010. 5 (11): 1977-80 DOI: 10.2215/CJN.00650110 
https://cjasn.asnjournals.org/content/5/11/1977.long

Brebner, J. Sandhu, K. Addison, C. Kapadia, S. Implementing electronic patient handover in a district general hospital. Clinical Risk. 2011. 17: 92-6 DOI: 10.1258/cr.2010.010078 
https://journals.sagepub.com/doi/abs/10.1258/cr.2010.010078

Benavente, D. Chue, CD. Moore, J. Addison, C. Borrows, R. Ferro, CJ. Serum phosphate measured at 6 and 12 months after successful kidney transplant is independently associated with subsequent graft loss. Exp Clin Transplant. 2012. 10 (2):119-24. DOI: 10.6002/ect.2011.0110 
http://www.ectrx.org/forms/ectrxcontentshow.phpyear=2012&volume=10&issue=2&supplement=0&makale_no=0&spage_number=119&content_type=FULL%20TEXT

Kapadia, S. Addison, CE. Developing clinical handover: what does the literature suggest? International Journal of Clinical Leadership. 2012. 17 (3): 119-122

Green CE & Turner AM, Role of COPD in lung cancer pathogenesis. World J Respirology. 2013. 3: 8-10 DOI: 10.5320/wjr.v3.i3.67. 
https://www.wjgnet.com/2218-6255/full/v3/i3/67.htm

Hutchison CA, Burmeister A, Harding SJ, Basnayake K, Church H, Jesky  MD, White K, Green CE. Stringer, SJ. Bassett, P. Ferro, CJ. Cockwell, P. Serum Polyclonal Immunoglobulin Free Light Chain Levels Predict Mortality in Chronic Kidney Disease. Mayo Clin Proc. 2014. 89 (5):615-22 DOI: 10.1016/j.mayocp.2014.01.028
https://www.sciencedirect.com/science/article/pii/S0025619614001657?via%3Dihub

Green, CE. Vayalapra, S. Hampson, JA. Mukherjee, D. Turner, AM. PiSZ alpha-1 antitrypsin deficiency (AATD): pulmonary phenotype and prognosis relative to PiZZ AATD and PiMM COPD. Thorax. 2015. 70 (10):939-45 DOI: 10.1136/thoraxjnl-2015-206906 
https://thorax.bmj.com/content/70/10/939.long

Green, CE. Parr, DG. Edgar, RG. Stockley, RA. Turner, AM. Lung density associates with survival in alpha 1 antitrypsin patients. Respir Med. 2016. 112:81-7 DOI: 10.1016/j.rmed.2016.01.007 
https://www.sciencedirect.com/science/article/pii/S095461111630004X?via%3Dihub

Green, CE & Turner, AM. The role of the endothelium in asthma and chronic obstructive pulmonary disease (COPD). Respir Res. 2017. 18 (1):20 DOI: 10.1186/s12931-017-0505-1.
https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-017-0505-1