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Geng, A, Brenig, RG, Roux, J, Lütge, M, Cheng, H-W, Flint, EE, Lussier, POG, Meier, M-A, Pop, OT, Künzler-Heule, P, Matter, MS, Wendon, J, McPhail, MJW, Soysal, S, Semela, D, Heim, M, Weston, CJ, Ludewig, B & Bernsmeier, C 2025, 'Circulating monocytes upregulate CD52 and sustain innate immune function in cirrhosis unless acute decompensation emerges', J Hepatol. https://doi.org/10.1016/j.jhep.2024.12.031
Al-Shakhshir, S, Quraishi, MN, Mullish, B, Patel, A, Vince, A, Rowe, A, Homer, V, Jackson, N, Gyimah, D, Shabir, S, Manzoor, S, Cooney, R, Alrubaiy, L, Quince, C, van Schaik, W, Hares, MF, Beggs, AD, Efstathiou, E, Rimmer, P, Weston, C, Iqbal, T & Trivedi, PJ 2025, 'FAecal micRobiota transplantation in primary sclerosinG chOlangitis (FARGO): study protocol for a randomised, multicentre, phase IIa, placebo-controlled trial', BMJ open, vol. 15, no. 1, e095392. https://doi.org/10.1136/bmjopen-2024-095392
Horn, P, Norlin, J, Almholt, K, Viuff, BM, Galsgaard, ED, Hald, A, Zosel, F, Demuth, H, Poulsen, S, Norby, PL, Rasch, MG, Vyberg, M, Fleckner, J, Werge, MP, Gluud, LL, Rink, MR, Shepherd, E, Northall, E, Lalor, PF, Weston, CJ, Fog-Tonnesen, M & Newsome, PN 2024, 'Evaluation of Gremlin-1 as a therapeutic target in metabolic dysfunction-associated steatohepatitis', eLife, vol. 13, RP95185. https://doi.org/10.7554/elife.95185
Davies, SP, Ronca, V, Wootton, GE, Krajewska, NM, Bozward, AG, Fiancette, R, Patten, DA, Yankouskaya, K, Reynolds, GM, Pat, S, Osei-Bordom, DC, Richardson, N, Grover, LM, Weston, CJ & Oo, YH 2024, 'Expression of E-cadherin by CD8+ T cells promotes their invasion into biliary epithelial cells', Nature Communications, vol. 15, no. 1, 853. https://doi.org/10.1038/s41467-024-44910-2
Matchett, KP, Wilson-Kanamori, JR, Portman, JR, Kapourani, CA, Fercoq, F, May, S, Zajdel, E, Beltran, M, Sutherland, EF, Mackey, JBG, Brice, M, Wilson, GC, Wallace, SJ, Kitto, L, Younger, NT, Dobie, R, Mole, DJ, Oniscu, GC, Wigmore, SJ, Ramachandran, P, Vallejos, CA, Carragher, NO, Saeidinejad, MM, Quaglia, A, Jalan, R, Simpson, KJ, Kendall, TJ, Rule, JA, Lee, WM, Hoare, M, Weston, CJ, Marioni, JC, Teichmann, SA, Bird, TG, Carlin, LM & Henderson, NC 2024, 'Multimodal decoding of human liver regeneration', Nature, vol. 630, no. 8015, pp. 158-165. https://doi.org/10.1038/s41586-024-07376-2
Wilkinson, AL, Bannister, ME, O'Keeffe, A, Weston, CJ, Lalor, PF, Shetty, S & Patten, DA 2024, 'Protocol to study monocyte transmigration across primary human liver endothelial cells under physiological shear flow conditions in vitro', STAR Protocols, vol. 5, no. 4, 103431. https://doi.org/10.1016/j.xpro.2024.103431
Hirschfield, G, Arndtz, K, Kirkham, A, Chen, Y-Y, Fox, R, Rowe, A, Douglas-Pugh, J, Thorburn, D, Barnes, E, Aithal, GP, Hull, D, Bhandal, K, Olsen, K, Woodward, P, Lax, S, Newsome, P, Smith, D, Kallio, A, Adams, D, Homer, V & Weston, C 2024, 'Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: open-label, multi-centre, single arm, phase II trial', Hepatology Communications, vol. 8, no. 5, e0426. https://doi.org/10.1097/HC9.0000000000000426
Pop, O-T, Geng, A, Flint, E, Singanayagam, A, Ercan, C, Possamai, L, Patel, VC, Kuenzler, P, Meier, M-A, Soysal, S, Hruz, P, Kollmar, O, Tatham, KC, Ward, JK, Müllhaupt, B, Weber, A, Wendon, J, Niess, JH, Heim, M, Semela, D, Weston, C, Antoniades, CG, Terracciano, LM, Triantafyllou, E, Brenig, RG & Bernsmeier, C 2023, 'AXL expression on homeostatic resident liver macrophages is reduced in cirrhosis following GAS6 production by hepatic stellate cells', Cellular and molecular gastroenterology and hepatology. https://doi.org/10.1016/j.jcmgh.2023.03.007
Greenman, R, Segal-Salto, M, Barashi, N, Hay, O, Katav, A, Levi, O, Vaknin, I, Aricha, R, Aharoni, S, Snir, T, Mishalian, I, Olam, D, Amer, J, Salhab, A, Safadi, R, Maor, Y, Trivedi, P, Weston, CJ, Saffioti, F, Hall, A, Pinzani, M, Thorburn, D, Peled, A & Mor, A 2023, 'CCL24 regulates biliary inflammation and fibrosis in primary sclerosing cholangitis', JCI Insight, vol. 8, no. 12, e162270. https://doi.org/10.1172/jci.insight.162270
Hall, C, Law, JP, Reyat, JS, Cumberland, MJ, Hang, S, Vo, NTN, Raniga, K, Weston, CJ, O’Shea, C, Townend, JN, Gehmlich, K, Ferro, CJ, Denning, C & Pavlovic, D 2023, 'Chronic activation of human cardiac fibroblasts in vitro attenuates the reversibility of the myofibroblast phenotype', Scientific Reports, vol. 13, no. 1, 12137. https://doi.org/10.1038/s41598-023-39369-y
Arndtz, K, Chen, YY, Rowe, A, Homer, V, Kirkham, A, Douglas-Pugh, J, Slade, D, Thorburn, D, Barnes, E, Aithal, G, Newsome, P, Smith, D, Adams, D, Weston, C & Hirschfield, G 2022, 'Monoclonal antibody BTT1023 targeting vascular adhesion protein 1 for treating primary sclerosing cholangitis: BUTEO single-arm Phase II trial', Efficacy and Mechanism Evaluation, vol. 9, no. 1. https://doi.org/10.3310/ZPNF4670
El-awaisi, J, Kavanagh, D, Rink, M, Weston, C, Drury, N & Kalia, N 2022, 'Targeting IL-36 improves age-related coronary microcirculatory dysfunction and attenuates myocardial ischemia/ reperfusion injury in mice: ageing and the coronary microcirculation ', JCI Insight, vol. 7, no. 5, e155236. https://doi.org/10.1172/jci.insight.155236
James, BH, Papakyriacou, P, Gardener, MJ, Gliddon, L, Weston, CJ & Lalor, PF 2022, 'The Contribution of Liver Sinusoidal Endothelial Cells to Clearance of Therapeutic Antibody', Frontiers in Physiology, vol. 12, 753833. https://doi.org/10.3389/fphys.2021.753833
Abstract
El-awaisi, J, Kavanagh, D, Rink, M, Weston, C, Drury, N & Kalia, N 2022, 'Intravital & laser speckle investigations of the role of interleukin-36 in myocardial ischaemia reperfusion injury – a new therapeutic target for the aged heart', Journal of Molecular and Cellular Cardiology, vol. 173, no. supplement, pp. 7. https://doi.org/10.1016/j.yjmcc.2022.08.017
Review article
Greenman, R & Weston, CJ 2025, 'CCL24 and Fibrosis: A Narrative Review of Existing Evidence and Mechanisms', Cells, vol. 14, no. 2, 105. https://doi.org/10.3390/cells14020105
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