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Horn, P, Norlin, J, Almholt, K, Viuff, BM, Galsgaard, ED, Hald, A, Zosel, F, Demuth, H, Poulsen, S, Norby, PL, Rasch, MG, Vyberg, M, Fleckner, J, Werge, MP, Gluud, LL, Rink, MR, Shepherd, E, Northall, E, Lalor, PF, Weston, CJ, Fog-Tonnesen, M & Newsome, PN 2024, 'Evaluation of Gremlin-1 as a therapeutic target in metabolic dysfunction-associated steatohepatitis', eLife, vol. 13, RP95185. https://doi.org/10.7554/elife.95185
Podlogar, T, Shad, BJ, Seabright, AP, Odell, OJ, Lord, SO, Civil, R, Salgueiro, RB, Shepherd, EL, Lalor, PF, Elhassan, YS, Lai, Y-C, Rowlands, DS & Wallis, GA 2023, 'Postexercise muscle glycogen synthesis with glucose, galactose, and combined galactose-glucose ingestion', American Journal of Physiology - Endocrinology and Metabolism, vol. 325, no. 6, pp. E672-E681. https://doi.org/10.1152/ajpendo.00127.2022
Wilkinson, AL, Hulme, S, Kennedy, JI, Mann, ER, Horn, P, Shepherd, EL, Yin, K, Zaki, MYW, Hardisty, G, Lu, W-Y, Rantakari, P, Adams, DH, Salmi, M, Hoare, M, Patten, DA & Shetty, S 2023, 'The senescent secretome drives PLVAP expression in cultured human hepatic endothelia to promote monocyte transmigration', iScience, vol. 26, no. 10, 107966. https://doi.org/10.1016/j.isci.2023.107966
Coltman, NJ, Coke, BA, Chatzi, K, Shepherd, EL, Lalor, PF, Schulz-Utermoehl, T & Hodges, NJ 2021, 'Application of HepG2/C3A liver spheroids as a model system for genotoxicity studies', Toxicology Letters, vol. 345, pp. 34-45. https://doi.org/10.1016/j.toxlet.2021.04.004
Shepherd, EL, Karim, S, Newsome, PN & Lalor, PF 2020, 'Inhibition of vascular adhesion protein-1 modifies hepatic steatosis in vitro and in vivo', World journal of hepatology, vol. 12, no. 11, pp. 931-948. https://doi.org/10.4254/wjh.v12.i11.931
Shepherd, E, Saborano, R, Northall, E, Matsuda, K, Ogino, H, Yashiro, H, Pickens, J, Feaver, RE, Cole, BK, Hoang, SA, Lawson, MJ, Olson, M, Figler, RA, Reardon, JE, Nishigaki, N, Wamhoff, BR, Gunther, U, Hirschfield, G, Erion, DM & Lalor, T 2020, 'Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis', JHEP Reports, vol. 2020, 100217. https://doi.org/10.1016/j.jhepr.2020.100217
Chauhan, A, Sheriff, L, Hussain, MT, Webb, GJ, Patten, DA, Shepherd, EL, Shaw, R, Weston, CJ, Haldar, D, Bourke, S, Bhandari, R, Watson, S, Adams, DH, Watson, SP & Lalor, PF 2020, 'The platelet receptor CLEC-2 blocks neutrophil mediated hepatic recovery in acetaminophen induced acute liver failure', Nature Communications, vol. 11, no. 1, 1939. https://doi.org/10.1038/s41467-020-15584-3
Patten, DA, Shepherd, EL, Weston, CJ & Shetty, S 2019, 'Novel targets in the immune microenvironment of the hepatic sinusoids for treating liver diseases', Seminars in Liver Disease, vol. 39, no. 2, pp. 111-123. https://doi.org/10.1055/s-0039-1678727
Bhogal, R, Weston, C, Velduis, S, Henri GD, L, Reynolds, G, Davies, S, Luu, N-T, Alfaifi, M, Shepherd, E, Boteon, Y, Wallace, L, Oo, YH, Adams, D, Mirza, DF, Mergentel, H, Muirhead, G, Stephenson, B & Afford, S 2018, 'The ROS-Mitophagy Signalling Pathway regulates liver endothelial cell survival during ischaemia-reperfusion injury', Liver Transplantation. https://doi.org/10.1002/lt.25313
Wadkin, JCR, Patten, DA, Kamarajah, S, Shepherd, EL, Novitskaia, V, Berditchevski, F, Adams, DH, Weston, CJ & Shetty, S 2017, 'CD151 supports VCAM-1 mediated lymphocyte adhesion to liver endothelium and is upregulated in chronic liver diseases and hepatocellular carcinoma', American journal of physiology. Gastrointestinal and liver physiology, vol. 313, no. 2, pp. G138-G149. https://doi.org/10.1152/ajpgi.00411.2016
Patten, DA, Kamarajah, SK, Rose, JM, Tickle, J, Shepherd, EL, Adams, DH, Weston, CJ & Shetty, S 2017, 'SCARF-1 promotes adhesion of CD4+ T cells to human hepatic sinusoidal endothelium under conditions of shear stress', Scientific Reports, vol. 7, 17600. https://doi.org/10.1038/s41598-017-17928-4
Ward, ST, Weston, CJ, Shepherd, EL, Hejmadi, R, Ismail, T & Adams, DH 2016, 'Evaluation of serum and tissue levels of VAP-1 in colorectal cancer', BMC Cancer, vol. 16, no. 1, 154. https://doi.org/10.1186/s12885-016-2183-7
Wilhelm, A, Shepherd, E, Amatucci, A, Munir, M, Reynolds, G, Humphreys, E, Resheq, Y, Adams, DH, Hubscher, S, Burkly, LC, Weston, C & Afford, S 2016, 'Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation', Journal of Pathology, vol. 239, no. 1, pp. 109–121. https://doi.org/10.1002/path.4707
Chapter
Shepherd, EL, Northall, E, Papakyriacou, P, Safranska, K, Sorensen, KK & Lalor, PF 2023, Decellularization of the Human Liver to Generate Native Extracellular Matrix for Use in Automated Functional Assays with Stellate Cells. in Hepatic Stellate Cells: Methods and Protocols. 1 edn, vol. 2669, Methods in molecular biology (Clifton, N.J.), pp. 233-244. https://doi.org/10.1007/978-1-0716-3207-9_14
Editorial
Adams, DH, Shepherd, EL & Lalor, PF 2018, 'Could endothelial TGFβ signaling be a promising new target for liver disease?', Expert review of gastroenterology & hepatology, vol. 12, no. 7, pp. 637-639. https://doi.org/10.1080/17474124.2018.1477587
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