Professor Subrata Ghosh MD, FRCP, FRCPE, FRCPC, FCAHS

Department of Immunology and Immunotherapy
Honorary Professor

Contact details

Telephone: +44 (0)121 371 8047
Email: s.ghosh@bham.ac.uk

Address: Institute of Translational Medicine
College of Medical and Dental Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Professor Ghosh's interest and vision is to enable and synergise scientific discoveries into rapid translation to bedside of patients for their benefit. He is especially interested in immune mediated inflammatory diseases such as Crohn’s disease and Ulcerative colitis.

Qualifications

F.R.C.P.C, Royal College of Physicians and Surgeons of Canada, 2009
F.R.C.P.(London), Royal College of Physicians of London, 2002
F.R.C.P.(Edinburgh), Royal College of Physicians of Edinburgh, 1997
Doctorate of Medicine (Research), in Gastroenterology, University of Edinburgh, 1996
ECFMG (steps 1 & 2), 1991
MRCP (London), Royal College of Physicians of London, 1988
Diplomate National Board, National Board of Examinations, India, 1987
MD (Internal Medicine), University of Calcutta, India (postgraduate degree in internal Medicine), 1986
Bachelor of Medicine & Surgery (MBBS), University of Calcutta, India, 1982

Biography

Subrata Ghosh moved from Canada where he was the Professor of Medicine at University of Calgary. He was cross-appointed as Professor of Immunology and microbiology and was an adjunct Professor in the department of veterinary medicine.

He was the Head of the Department of Medicine at Cumming School of Medicine, University of Calgary and the Zone Clinical Department Head, Calgary Zone, Alberta Health Services. Previously, he was the Chair of Gastroenterology and Professor of Gastroenterology at the Imperial College London, Hammersmith Hospital and associate professor of gastroenterology at University of Edinburgh. Professor Ghosh is a Fellow of the Canadian Academy of Health Sciences and a member of the International Organization for the Study of IBD.

He is a past editor in chief of the Canadian Journal of Gastroenterology and Hepatology, editor in chief of World Journal of Gastroenterology and associate editor of Gut, and sits on the editorial boards of several journals. He served on the Scientific Advisory Committee of the Crohn’s and Colitis Canada and Chaired its of Advocacy Committee and he was the chairman of the medical advisors of the Crohn’s and Colitis UK. Prof Ghosh has published over 470 manuscripts (h index 87). He has delivered over 600 international lectures. His research interests are focused on translational immunology of inflammatory bowel disease and novel therapeutic approaches.

Postgraduate supervision

Subrata has supervised over 20 PhD students and his laboratory is open. He is currently supervising or co-supervising 4 PhD students.

Research

Subrata's research interests span aetiopathology of IBD, immune disorders in IBD, Biomarkers in IBD, Treatment of IBD. A major focus is on dendritic cell and T cell interactions in IBD and targeting these interactions by pharmacological targeted therapies as well as by nutrient modulation.

Other activities

Nominated member International Organization for Study of IBD
Fellow of the Canadian Association of Health Sciences
Crohn’s and Colitis Canada –member of the scientific advisory board
Crohn’s and Colitis Canada – chairman of the advocacy committee
Crohn’s and Colitis UK- chairman of the medical advisors group

Publications

Recent publications

Article

Shivaji, U, Bazarova, A, Critchlow, T, Smith, SCL, Nardone, O, Love, M, Davis, J, Ghosh, S & Iacucci, M 2021, 'Clinical outcomes, predictors of prognosis and health economics consequences in IBD patients after discontinuation of the first biological therapy', Therapeutic Advances in Gastroenterology, vol. 13, pp. 1-16. https://doi.org/10.1177/1756284820981216

Smith, SCL, Banbury, C, Zardo, D, Cannatelli, R, Nardone, OM, Shivaji, UN, Ghosh, S, Oppenheimer, PG & Iacucci, M 2021, 'Raman spectroscopy accurately differentiates mucosal healing from non-healing and biochemical changes following biological therapy in inflammatory bowel disease', PLoS ONE, vol. 16, no. 6, e0252210. https://doi.org/10.1371/journal.pone.0252210

Smith, SCL, Siau, K, Cannatelli, R, Antonelli, G, Shivaji, UN, Ghosh, S, Saltzman, JR, Hassan, C & Iacucci, M 2021, 'Training methods in optical diagnosis and characterization of colorectal polyps: a systematic review and meta-analysis', Endoscopy International Open, vol. 9, no. 5, pp. E716-E726. https://doi.org/10.1055/a-1381-7181

Iacucci, M, Jeffery, L, Acharjee, A, Nardone, OM, Zardo, D, Smith, SCL, Bazarova, A, Cannatelli, R, Shivaji, UN, Williams, J, Gkoutos, G & Ghosh, S 2021, 'Ultra-high magnification endocytoscopy and molecular markers for defining endoscopic and histologic remission in ulcerative colitis—an exploratory study to define deep remission', Inflammatory Bowel Diseases. https://doi.org/10.1093/ibd/izab059

Zhang, Z, Taylor, L, Shommu, N, Ghosh, S, Reimer, R, Panaccione, R, Kaur, S, Hyun, JE, Cai, C, Deehan, EC, Hotte, N, Madsen, KL & Raman, M 2020, 'A diversified dietary pattern is associated with a balanced gut microbial composition of Faecalibacterium and Escherichia/Shigella in patients with Crohn's disease in remission', Journal of Crohn's & Colitis. https://doi.org/10.1093/ecco-jcc/jjaa084

Smith, S, Bazarova, A, Ejenavi , E, Qurashi, M, Shivaji, U, Harvey , PR, Slaney, E, McFarlane, M, Baker, G, Elnagar, M, Yuzari , S, Gkoutos, GV, Ghosh, S & Iacucci, M 2020, 'A multicentre development and validation study of a novel Lower Gastrointestinal Bleeding score-The Birmingham Score', International journal of colorectal disease, vol. 35, pp. 285–293. https://doi.org/10.1007/s00384-019-03459-z

Quraishi, MN, Acharjee, A, Beggs, AD, Horniblow, R, Tselepis, C, Gkoutos, G, Ghosh, S, Rossiter, A, Loman, N, van Schaik, W, Withers, D, Walters, JRF, Hirschfield, GM & Iqbal, TH 2020, 'A pilot integrative analysis of colonic gene expression, gut microbiota, and immune infiltration in primary sclerosing cholangitis-inflammatory bowel disease: association of disease with bile acid pathways', Journal of Crohn's & Colitis, vol. 14, no. 7, pp. 935-947. https://doi.org/10.1093/ecco-jcc/jjaa021

Iacucci, M, Smith, SCL, Bazarova, A, Shivaji, U, Bhandari, P, Cannatelli, R, Daperno, M, Ferraz, J, Goetz, M, Gui, X, Hayee, B, De Hertogh, G, Lazarev, M, Li, J, Nardone, O, Parra-Blanco, A, Pastorelli, L, Panaccione, R, Occhipinti, V, Rath, T, Tontini, GE, Vieth, M, Villanacci, V, Zardo , D, Bisschops, R, Kiesslich, R & Ghosh, S 2020, 'An international multicenter real-life prospective study of electronic chromoendoscopy score PICaSSO in ulcerative colitis', Gastroenterology. https://doi.org/10.1053/j.gastro.2020.12.024

Iacucci, M, Ghosh, S, Cannatelli, R, Gui, XS, Bazarova, A, Zardo , D, Gkoutos, G, Lethebe, BC, Kaplan, GG, Panaccione, R, Kiesslich, R & Ghosh, S 2020, 'Assessment of endoscopic healing by using advanced technologies reflects histologic healing in ulcerative colitis', Journal of Crohn's & Colitis. https://doi.org/10.1093/ecco-jcc/jjaa056

Tan, N-D, Qiu, Y, Xing, X-B, Ghosh, S, Chen, M-H & Mao, R 2020, 'Associations between angiotensin converting enzyme inhibitors and angiotensin II receptor blocker use, gastrointestinal symptoms, and mortality among patients with COVID-19', Gastroenterology. https://doi.org/10.1053/j.gastro.2020.05.034

Kennedy, NA, Jones, G-R, Lamb, CA, Appleby, R, Arnott, I, Beattie, RM, Bloom, S, Brooks, AJ, Cooney, R, Dart, RJ, Edwards, C, Fraser, A, Gaya, DR, Ghosh, S, Greveson, K, Hansen, R, Hart, A, Hawthorne, AB, Hayee, BH, Limdi, JK, Murray, CD, Parkes, GC, Parkes, M, Patel, K, Pollok, RC, Powell, N, Probert, CS, Raine, T, Sebastian, S, Selinger, C, Smith, PJ, Stansfield, C, Younge, L, Lindsay, JO, Irving, PM & Lees, CW 2020, 'British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic', Gut, vol. 69, no. 6, pp. 984-990. https://doi.org/10.1136/gutjnl-2020-321244

Sandborn, WJ, Feagan, BG, Loftus, EV, Peyrin-biroulet, L, Van Assche, G, D’haens, G, Schreiber, S, Colombel, J, Lewis, JD, Ghosh, S, Armuzzi, A, Scherl, E, Herfarth, H, Vitale, L, Mohamed, MF, Othman, AA, Zhou, Q, Huang, B, Thakkar, RB, Pangan, AL, Lacerda, AP & Panes, J 2020, 'Efficacy and safety of upadacitinib in a randomized trial of patients with Crohn’s disease', Gastroenterology. https://doi.org/10.1053/j.gastro.2020.01.047

Sandborn , WJ, Ghosh, S, Panes, J, Schreiber, S, D'Haens, G, Tanida, S, Siffledeen, J, Enejosa, J, Zhou, W, Ahmed, O, Huang, B & Higgins, PDR 2020, 'Efficacy of upadacitinib in a randomized trial of patients with active ulcerative colitis', Gastroenterology, vol. 158, no. 8, pp. 2139-2149.e14. https://doi.org/10.1053/j.gastro.2020.02.030

Hanauer, SB, Sandborn, WJ, Feagan, BG, Gasink, C, Jacobstein, D, Zou, B, Johanns, J, Adedokun, OJ, Sands, BE, Rutgeerts, P, de Villiers, WJS, Colombel, J-F & Ghosh, S 2020, 'IM-UNITI: Three-year Efficacy, Safety, and Immunogenicity of Ustekinumab Treatment of Crohn's Disease', Journal of Crohn's & Colitis, vol. 14, no. 1, pp. 23-32. https://doi.org/10.1093/ecco-jcc/jjz110

Review article

Nardone, O, Iaccuci, M, Ghosh, S & Castiglione, F 2020, 'Can a transition clinic bridge the gap between paediatric and adult inflammatory bowel disease', Digestive and Liver Disease, vol. 52, no. 5, pp. 516-527. https://doi.org/10.1016/j.dld.2020.02.009

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