Miss Hongdi Wang BEng

School of Chemical Engineering
Visiting PhD Student

Contact details

Telephone: +44 (0) 7761319247
Email: hxw674@bham.ac.uk
Twitter: @Wang_Hongdi

Address: School of Chemical Engineering
University of Birmingham
Edgbaston
Birmingham
B15 2TT

Hongdi Wang is currently doing her MSc & PhD in Chemical Engineering under Professor Zhibing Zhang and Professor Yanbin Jiang (South China University of Technology). Her current research mainly focuses on the design and fabrication of anticancer drug nano/micro-crystals based drug delivery system, particularly their encapsulation and functionalization for targeting delivery and satisfactory therapeutic effect.

Qualifications

BEng in School of chemical engineering, Qingdao University of Science & Technology, 2012

Biography

Hongdi Wang qualified with a BEng degree in Chemical Engineering from Qingdao University of Science & Technology, China in 2012.

She then joined the South China University of Technology to study for a MSc & PhD degree in an interdiscipline of Chemical Engineering and Biomedicine. During her PhD study, she had two years’ experiences in College of Life Science and Technology, Jinan University doing the intracellular localization, targeting accumulation and biostability of nanoparticles in vitro and in vivo.

After that, she joined the University of Birmingham in 2016 as a visiting PhD student and carried out research on mechanical properties study of protein-based carriers to achieve superior tableting performance.

Research

Design and fabrication of versatile nanocarriers, their typical drug encapsulation and functionalization for targeting delivery.

Physicochemical and mechanical properties study of protein- based nano/micro-carrier systems including breakability, flowability, stability and the controlled release.

Publications

Wang H. D., Feng J. L., Liu G. J., Cheng B. Q., Jiang Y. B., Xie Q. L., (2016), In vitro and in vivo anti-tumor efficacy of
10-hydroxycamptothecin polymorphic nanoparticle dispersions: shape- and polymorph- dependent cytotoxicity and delivery of 10 hydroxycamptothecin to cancer cells, Nanomedicine: Nanotechnology, Biology, and Medicine, 12: 881-891.
Wang H. D., Jiang Y. B., 10-Hydroxycamptothecin polymorphic nanoparticle dispersions: preparation, in vitro release rate and cytotoxicity study, The 1st International Symposium on Translational Nanomedicine, Jan. 2015, Guangzhou, China (Refereed conference paper plus Poster presentation).
Liu G. J., Wang H. D., Jiang Y. B., (2013), Recrystallization and micronization of camptothecin by supercritical antisolvent process: influence of solvents. Ind. Eng. Chem. Res., 52: 15049-15056.
Huang Y. X., Wang H. D., Liu G. J., Jiang Y. B., (2015), New polymorphs of 9-nitro- camptothecin prepared using a supercritical anti-solvent process, Int. J. Pharm., 496:551-560.
Liu G. J., Wang W., Wang H. D., Jiang Y. B.. (2014), Preparation of liposome-encapsulated 10-hydroxycamptothecin nanoparticles by the supercritical CO2 anti-solvent Process, Chem. Eng. J., 243:289-296.