Recent publications
Article
Chua, W, Khashaba, A, Canagarajah, H, Nielsen, JC, di Biase, L, Haeusler, KG, Hindricks, G, Mont, L, Piccini, J, Schnabel, RB, Schotten, U, Wienhues-Thelen, U-H, Zeller, T, Fabritz, L & Kirchhof, P 2024, 'Disturbed atrial metabolism, shear stress, and cardiac load contribute to atrial fibrillation after ablation: AXAFA biomolecule study', Europace, vol. 26, no. 2, euae028. https://doi.org/10.1093/europace/euae028
Fabritz, L, Fortmueller, L, Gehmlich, K, Kant, S, Kemper, M, Kucerova, D, Syeda, F, Faber, C, Leube, R, Kirchhof, P & Krusche, CA 2024, 'Endurance training provokes Arrhythmogenic Right Ventricular Cardiomyopathy phenotype in heterozygous Desmoglein 2 mutants: Alleviation by preload reduction', Biomedicines, vol. 12, no. 5, 985. https://doi.org/10.3390/biomedicines12050985
Linz, D, Andrade, JG, Arbelo, E, Boriani, G, Breithardt, G, Camm, AJ, Caso, V, Nielsen, JC, De Melis, M, De Potter, T, Dichtl, W, Diederichsen, SZ, Dobrev, D, Doll, N, Duncker, D, Dworatzek, E, Eckardt, L, Eisert, C, Fabritz, L, Farkowski, M, Filgueiras-Rama, D, Goette, A, Guasch, E, Hack, G, Hatem, S, Haeusler, KG, Healey, JS, Heidbuechel, H, Hijazi, Z, Hofmeister, LH, Hove-Madsen, L, Huebner, T, Kääb, S, Kotecha, D, Malaczynska-Rajpold, K, Merino, JL, Metzner, A, Mont, L, Ng, GA, Oeff, M, Parwani, AS, Puererfellner, H, Ravens, U, Rienstra, M, Sanders, P, Scherr, D, Schnabel, R, Schotten, U, Sohns, C, Steinbeck, G, Steven, D, Toennis, T, Tzeis, S, van Gelder, IC, van Leerdam, RH, Vernooy, K, Wadhwa, M, Wakili, R, Willems, S, Witt, H, Zeemering, S & Kirchhof, P 2024, 'Longer and better lives for patients with atrial fibrillation: the 9th AFNET/EHRA consensus conference', Europace, vol. 26, no. 4, euae070. https://doi.org/10.1093/europace/euae070
Khan, N, Steeds, R, Kyte, D, Fabritz, L, Collis, P, Chua, WWL, Stubbs, C, Mehta, S, Sun, Y, Nulty, M, Kirkham, K & Cotton, JM 2024, 'Pilot study to evaluate the use of remote patient monitoring to guide the timing of valve intervention in patients with severe asymptomatic aortic stenosis (APRAISE-AS): study protocol for a randomised controlled trial delivered in two tertiary cardiac centres in the UK', BMJ open, vol. 14, no. 6, e086587. https://doi.org/10.1136/bmjopen-2024-086587
Reyat, J, Sommerfeld, L, O'Reilly, M, Roth Cardoso, V, Thiemann, E, Khan, A, O'Shea, C, Harder, S, Müller, C, Barlow, J, Stapley, R, Chua, WWL, Kabir, N, Grech, O, Hummel, O, Hübner, N, Kaab, S, Mont, L, Hatem, SN, Winters, J, Zeemering, S, Morgan, N, Rayes, J, Gehmlich, K, Stoll, M, Brand, T, Schweizer , M, Piasecki, A, Schotten, U, Gkoutos, G, Lorenz, K, Cuello, F, Kirchhof, P & Fabritz, L 2024, 'PITX2 deficiency leads to atrial mitochondrial dysfunction', Cardiovascular Research. https://doi.org/10.1093/cvr/cvae169
Rinné, S, Kiper, AK, Jacob, R, Ortiz-Bonnin, B, Schindler, RFR, Fischer, S, Komadowski, M, deMartino, E, Schafer, MK-H, Cornelius, T, Fabritz, L, Helker, CSM, Brand, T & Decher, N 2024, 'Popeye-domain-containing proteins modulate the voltage-gated cardiac sodium channel Nav1.5', iScience. https://doi.org/10.1016/j.isci.2024.109696
Sommerfeld, LC, Holmes, AP, Yu, TY, O'Shea, C, Kavanagh, DM, Pike, JM, Wright, T, Syeda, F, Aljehani, A, Kew, T, Cardoso, VR, Kabir, SN, Hepburn, C, Menon, PR, Broadway‐Stringer, S, O'Reilly, M, Witten, A, Fortmueller, L, Lutz, S, Kulle, A, Gkoutos, GV, Pavlovic, D, Arlt, W, Lavery, GG, Steeds, R, Gehmlich, K, Stoll, M, Kirchhof, P & Fabritz, L 2024, 'Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse', The Journal of Physiology. https://doi.org/10.1113/jp284597
Rillig, A, Eckardt, L, Borof, K, Camm, AJ, Crijns, HJGM, Goette, A, Breithardt, G, Lemoine, MD, Metzner, A, Rottner, L, Schotten, U, Vettorazzi, E, Wegscheider, K, Zapf, A, Heidbuchel, H, Willems, S, Fabritz, L, Schnabel, RB, Magnussen, C & Kirchhof, P 2024, 'Safety and efficacy of long-term sodium channel blocker therapy for early rhythm control: the EAST-AFNET 4 trial', Europace, vol. 26, no. 6, euae121. https://doi.org/10.1093/europace/euae121
Aljehani, A, Baig, S, Kew, T, Kalla, M, Sommerfeld, LC, Murukutla, VA, Fabritz, L & Steeds, RP 2024, 'Structural Progression in Patients with Definite and Non-Definite Arrhythmogenic Right Ventricular Cardiomyopathy and Risk of Major Adverse Cardiac Events', Biomedicines, vol. 12, no. 2, 328. https://doi.org/10.3390/biomedicines12020328
Chua, W, Cardoso, VR, Guasch, E, Sinner, MF, Al-Taie, C, Brady, P, Casadei, B, Crijns, HJGM, Dudink, EAMP, Hatem, SN, Kääb, S, Kastner, P, Mont, L, Nehaj, F, Purmah, Y, Reyat, JS, Schotten, U, Sommerfeld, LC, Zeemering, S, Ziegler, A, Gkoutos, GV, Kirchhof, P & Fabritz, L 2023, 'An angiopoietin 2, FGF23, and BMP10 biomarker signature differentiates atrial fibrillation from other concomitant cardiovascular conditions', Scientific Reports, vol. 13, no. 1, 16743. https://doi.org/10.1038/s41598-023-42331-7
Aljehani, A, Kew, T, Baig, S, Cox, H, Sommerfeld, LC, Ensam, B, Kalla, M, Steeds, RP & Fabritz, L 2023, 'Characterisation of patients referred to a tertiary-level inherited cardiac condition clinic with suspected arrhythmogenic right ventricular cardiomyopathy (ARVC)', BMC Cardiovascular Disorders, vol. 23, no. 1, 14. https://doi.org/10.1186/s12872-022-03021-w
Schnabel, RB, Marinelli, EA, Arbelo, E, Boriani, G, Boveda, S, Buckley, CM, Camm, AJ, Casadei, B, Chua, W, Dagres, N, de Melis, M, Desteghe, L, Diederichsen, SZ, Duncker, D, Eckardt, L, Eisert, C, Engler, D, Fabritz, L, Freedman, B, Gillet, L, Goette, A, Guasch, E, Svendsen, JH, Hatem, SN, Haeusler, KG, Healey, JS, Heidbuchel, H, Hindricks, G, Hobbs, FDR, Hübner, T, Kotecha, D, Krekler, M, Leclercq, C, Lewalter, T, Lin, H, Linz, D, Lip, GYH, Løchen, ML, Lucassen, W, Malaczynska-Rajpold, K, Massberg, S, Merino, JL, Meyer, R, Mont, L, Myers, MC, Neubeck, L, Niiranen, T, Oeff, M, Oldgren, J, Potpara, TS, Psaroudakis, G, Pürerfellner, H, Ravens, U, Rienstra, M, Rivard, L, Scherr, D, Schotten, U, Shah, D, Sinner, MF, Smolnik, R, Steinbeck, G, Steven, D, Svennberg, E, Thomas, D, True Hills, M, van Gelder, IC, Vardar, B, Palà, E, Wakili, R, Wegscheider, K, Wieloch, M, Willems, S, Witt, H, Ziegler, A, Daniel Zink, M, Willems, S, Witt, H, Ziegler, A, Daniel Zink, M & Kirchhof, P 2023, 'Early diagnosis and better rhythm management to improve outcomes in patients with atrial fibrillation: the 8th AFNET/EHRA consensus conference', Europace, vol. 25, no. 1, pp. 6-27. https://doi.org/10.1093/europace/euac062
Kany, S, Cardoso, VR, Bravo, L, Williams, JA, Schnabel, R, Fabritz, L, Gkoutos, GV & Kirchhof, P 2022, 'Eligibility for early rhythm control in patients with atrial fibrillation in the UK Biobank', Heart. https://doi.org/10.1136/heartjnl-2022-321196
O'Reilly, M, Sommerfeld, LC, O'Shea, C, Broadway-Stringer, S, Andaleeb, S, Reyat, JS, Kabir, SN, Stastny, D, Malinova, A, Delbue, D, Fortmueller, L, Gehmlich, K, Pavlovic, D, Skryabin, BV, Holmes, AP, Kirchhof, P & Fabritz, L 2022, 'Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide', EP Europace. https://doi.org/10.1093/europace/euac218
Review article
ESC Task Force, Glikson, M, Nielsen, JC, Kronborg, MB, Michowitz, Y, Auricchio, A, Barbash, IM, Barrabes, JA, Boriani, G, Braunschweig, F, Brignole, M, Burri, H, Coats, AJS, Deharo, JC, Delgado, V, Diller, GP, Israel, CW, Keren, A, Knops, RE, Kotecha, D, Leclercq, C, Merkely, B, Starck, C, Thylen, I, Tolosana, JM, Leyva, F, Linde, C, Abdelhamid, M, Aboyans, V, Arbelo, E, Asteggiano, R, Barón-Esquivias, G, Bauersachs, J, Biffi, M, Birgersdotter-Green, U, Bongiorni, MG, Borger, MA, Celutkienė, J, Cikes, M, Daubert, JC, Drossart, I, Ellenbogen, K, Elliott, PM, Fabritz, L, Falk, V, Fauchier, L, Fernández-Aviles, F, Foldager, D, Gadler, F, De Vinuesa, PGG, Gorenek, B, Guerra, JM, Haugaa, KH, Hendriks, J, Kahan, T, Katus, HA, Konradi, A, Koskinas, KC, Law, H, Lewis, BS, Linker, NJ, Løchen, M-L, Lumens, J, Mascherbauer, J, Mullens, W, Nagy, KV, Prescott, E, Raatikainen, P, Rakisheva, A, Reichlin, T, Ricci, RP, Shlyakhto, E, Sitges, M, Sousa-Uva, M, Sutton, R, Suwalski, P, Svendsen, JH, Touyz, RM, Van Gelder, IC, Vernooy, K, Waltenberger, J, Whinnett, Z & Witte, KK 2022, '2021 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: Developed by the Task Force on cardiac pacing and cardiac resynchronization therapy of the European Society of Cardiology (ESC) With the special contribution of the European Heart Rhythm Association (EHRA)', Europace, vol. 24, no. 1, pp. 71-164. https://doi.org/10.1093/europace/euab232
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