Mr Prashant Patel MBBS, MS (Gen Surg), FRCS Ed (Gen), PhD, FRCS Ed (Urol), FEBU, MBA

Mr Prashant Patel

Department of Cancer and Genomic Sciences
Associate Clinical Professor, Urology

Contact details

Address
Department of Cancer and Genomic Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Prashant was jointly appointed in 2010 at the University of Birmingham (UoB) and Queen Elizabeth Hospital, Birmingham (QEHB) as a clinical academic after completing a year’s fellowship in Perth. He was head hunted and appointed at University College London Hospitals (Urology Dept. World Rank 7, Newsweek 2024) (UCLH) and Royal National Orthopaedic Hospital (RNOH) in November 2022 as an Advanced Pelvic and Retroperitoneal Surgeon. He is the Governance lead for Urology at UCLH. He was recently awarded a scholarship and is reading for an Executive MBA (Health) at University College London (UCL).

Qualifications

  • Executive Health MBA (in progress), UCL, London
  • FEBU (Fellowship of the European Board of Urology), 2018
  • FRCS Ed (Urol), 2009
  • PhD in Gene & Immunotherapy, University of Birmingham, 2008
  • FRCS Ed (General Surgery), 2001
  • PLAB (Professional Linguistics Assessment Board Examination), 1999
  • MS (General Surgery), University of Karnataka,1998
  • USMLE, ECFMG, USA, 1993
  • MBBS, University of Poona, 1991

Biography

Prashant Patel qualified in 1993 from India and then trained to qualify as a General Surgeon with special interest in pelvic surgery. He was awarded a PhD from the University of Birmingham whilst training as a Urologist. He travelled to Perth (2010), Australia to complete a fellowship in urological cancer surgery where he had exposure to laparoscopic and robotic surgery. He has professional registration with UK, India, USA, Australia as well has the Fellowship with European Board of Urology.

He was appointed as a Senior Lecturer in Urology at the University of Birmingham and Consultant Urological Surgeon at QE Hospital (UHB), Birmingham (2010) to pursue a joint career in academic and clinical urology. He was an Associate Clinical Professor of Urology and the Head of Department (Clinical Service Lead) 2019 - 2022 at the University Hospitals Birmingham (QE Hospital, Heartlands, Good Hope and Solihull Hospitals) where he led the service amalgamation, instituted robotic surgery at Solihull, appointed 9 consultants and restructured provision of Urology services across Birmingham during the Pandemic. He was head hunted by University College London Hospitals and Royal National Orthopaedic Hospital Stanmore to lead on advanced Pelvic and retro-peritoneal surgery in Jan 2023. He is also the Urology Governance lead at UCLH and currently awarded a scholarship towards an executive health MBA at UCL.

His clinical interests are in pelvic cancers (bladder and prostate) and Retro-peritoneal Lymph Node dissection (RPLND) for metastatic testicular cancer. He conducts cancer surgery ranging from routine straightforward cases to the highly complex and technically demanding operations. He mostly performs multi-speciality complex operations of the genito-urinary tract involving other specialities viz. Colo-rectal/Bowel, Sarcoma (Soft tissue and bone cancers), Gynaecology cancers, Complex Deep Endometriosis and Obstetrics (Placenta Accreta/Percreta). 

He keeps himself in check by keeping fit through endurance training involving: cycling, eating well, meditation and has summited several high altitude mountain peaks in Europe, Russia, Africa, South America, Nepal and India.

Teaching

Prashant is an accredited trainer and educational supervisor by the General Medical Council. He has been on the committee of National Urology Trainee selection since 2011. He is on the teaching faculty at the British Association of Urological Surgeons for the FRCS (Urology) Examinations. 

Postgraduate supervision

Prashant has supervised the following students:

MD

  • 2020-2022 - Umair Kamran - POUGIC – Quality Indicators of Upper GI Endoscopy (Funding: Joint with Dr Nigel Trudgill and SWBHT)
  • 2017 - 2020 - Omar Abdullah - VTE in Bladder Cancer (Funding: Joint with Professor Annie Young and Warwick University)
  • 2018 - 2020 - Dominic King - Outcomes of PTC and EUS biopsy for Pancreatic malignancies (Funding: Joint with Dr Nigel Trudgill and SWBHT)
  • 2018 - 2019 - Amandeep Dosanjh - Validation of Algorithms to predict an event using HES data in Urological cancers (Funding: Joint with Professor Nick James)
  • 2016 - 2018 - Phillip Harvey - Achalasia Cardia outcomes (Funding: Joint with Dr Nigel Trudgill and SWBHT)
  • 2015 - 2017 - Julien Al Shakarchi - Natural History of Vascular Access and pre-operative predictors of outcome (Funding: Joint with Mr Nick Inston and UHBFT)
  • 2014 - 2016 - James Rees - Changing outcomes for emergency Inflammatory Bowel Disease admissions in England (Funding: Joint with Dr Nigel Trudgill and SWBHT)
  • 2014 - 2015 - David Muthuveloe - Urological Cancer Outcomes on HES (Funding: UHBFT)
  • 2013 - 2015 - Vinney During - Immune responses in Bladder Cancer (Funding: Joint with Dr Graham Taylor and UHBFT)
  • 2012 - 2014 - Danny Cheung - Missed cancers in Endoscopy (Funding: Joint with Dr Nigel Trudgill and SWBHT)
  • 2011 - 2013 - Jane Anderson -  Role of Autotaxins in Urological cancers (Funding: Joint with Professor Paul Murray and UHBFT)

ChM (Urology)

  • 2016 -2017 - Ishtiakul Rizvi - Accuracy of Choline-PET CT to detect prostate cancer metastasis at low levels of PSA (Funding: Self)
  • 2016 -2017 - Sachin Yallapa - Role of Renal Nephrometry score in predicting renal dysfunction (Funding: Self – Gold Medal for the project

MSc

  • 2014 - 2016 - Yakhub Khan - Assessment of late radiotherapy toxicity in patients treated radically for prostate cancer: a comparison between different image verification techniques (Funding: Self)

BMedSci

  • 2014 - 2015 - Robert Telford - Correlation of template biopsy with MRI and prostatectomy (Funding: Self)

Research

Research Interests

His research interests are to explore molecular markers in bladder cancer, immunotherapeutic approaches in all urological cancers and informatics. He is extensively published with >140 peer reviewed articles in journals and book chapters. He is the Chief Investigator on Gene therapy clinical trial and is also a Principal investigator in several prostate and bladder cancer studies. He is a grant holder of several trials and studies. His research interests are also outside the field of Urology involving large datasets (informatics) where his team explore disease and outcome trends. This area of research has also led to recommendations in national guidance. Prashant is also the theme lead in Clinical Research and Epidemiology for the Bladder Cancer Research Centre in the Department of Cancer and Genomic Sciences.

Current Projects

 

Other activities

His international profile includes panellist and Chair on Bladder Cancer at the European Urology Annual Meetings over several years; Member of the Scientific Evaluation Committee for Translational Cancer Research at the French National Cancer Institute, and Frontiers Guest Associate Editor in Genitourinary Oncology.  

He is on the board of directors for the ManVan Charity and regularly participates in fundraising and raising awareness for Prostate, Bladder and Testicular cancers at several charity and BAME events.

Publications

Recent publications

Article

Dosanjh, A, Coupland, B, Mytton, J, King, DS, Mintz, H, Lock, A, Nanton, V, Mariappan, P, Trudgill, N & Patel, P 2024, 'High early mortality following percutaneous nephrostomy in metastatic cancer: a national analysis of outcomes', BMJ Supportive & Palliative Care. https://doi.org/10.1136/spcare-2024-004937

James, N, Pirrie, S, Liu, W, Catto, J, Jefferson, K, Patel, P, Hughes, A, Pope, A, Nanton, V, Mintz, HP, Knight, A, Gallagher, J & Bryan, RT 2024, 'Image directed redesign of bladder cancer treatment pathways: the BladderPath RCT', Health Technology Assessment, vol. 28, no. 42, pp. 1-65. https://doi.org/10.3310/DEHT5407

The BladderPath trial management group 2023, 'Properties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection', Scientific Reports, vol. 13, no. 1, 1060. https://doi.org/10.1038/s41598-023-27675-4

BladderPath Trial Management Group 2022, 'Highly sensitive and specific detection of bladder cancer via targeted ultra-deep sequencing of urinary DNA', European Urology Oncology. https://doi.org/10.1016/j.euo.2022.03.005

Tye, E, Jinks, E, Haigh, T, Kaul, B, Patel, P, Parry, H, Newby, M, Crispin, M, Kaur, N, Moss, P, Drennan, S, Taylor, G & Long, H 2022, 'Mutations in SARS-CoV-2 spike protein impair epitope-specific CD4+ T cell recognition', Nature Immunology, vol. 23, pp. 1726–1734. https://doi.org/10.1038/s41590-022-01351-7

King, D, Kamran, U, Dosanjh, A, Coupland, B, Mytton, J, Leeds, JS, Nayar, M, Patel, P, Oppong, KW & Trudgill, NJ 2022, 'Rate of pancreatic cancer following a negative endoscopic ultrasound and associated factors', Endoscopy. https://doi.org/10.1055/a-1784-1661

King, D, Coupland, B, Dosanjh, A, Cole, A, Ward, S, Reulen, R, Adderley, N, Patel, P & Trudgill, N 2022, 'The risk of subsequent surgery following bowel resection for Crohn’s disease in a national cohort of 19,207 patients', Colorectal Disease. https://doi.org/10.1111/codi.16331

Bryan, R, Liu, W, Pirrie, S, Amir, R, Gallagher, J, Hughes, A, Jefferson, K, Knight, A, Nanton, V, Mintz, H, Pope, A, Catto, J, Patel, P & James, N 2021, 'Comparing an imaging-guided pathway with the standard pathway for staging muscle-invasive bladder cancer: preliminary data from the BladderPath study', European urology, vol. 80, no. 1, pp. 12-15. https://doi.org/10.1016/j.eururo.2021.02.021

Kamran, U, King, D, Dosanjh, A, Coupland, B, Leeds, J, Nayar, M, Patel, P, Trudgill, N & Oppong, KW 2021, 'Pancreaticobiliary endoscopic ultrasound in England 2007 to 2016: changing practice and outcomes', Endoscopy International Open, vol. 9, no. 11, pp. E1731-E1739. https://doi.org/10.1055/a-1534-2558

COVIDSurg Collaborative & Hunt, L 2021, 'Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic', British Journal of Surgery, vol. 108, no. 1, pp. 88-96. https://doi.org/10.1093/bjs/znaa051

Rees, J, Evison, F, Mytton, J, Patel, P & Trudgill, N 2021, 'The outcomes of emergency hospital admissions with non-malignant upper gastrointestinal bleeding in England between 2003 and 2015', Endoscopy, vol. 53, no. 12, pp. 1210-1218. https://doi.org/10.1055/a-1330-7118

Comment/debate

Bryan, RT, Arnold, R, Khanim, FL, Shepherd, DE, Patel, P & Ward, DG 2021, 'Establishing the Bladder Cancer Research Centre at the University of Birmingham', Nature Reviews Urology, vol. 18, no. 6, pp. 318-320. https://doi.org/10.1038/s41585-021-00448-2

BladderPath Trial Management Group 2021, 'Reply to Trey Durdin, Alvin Goh, and Eugene Pietzak. Can an imaging-guided pathway replace the current paradigm for muscle-invasive bladder cancer?', European urology, vol. 80, no. 1, pp. 18-19. https://doi.org/10.1016/j.eururo.2021.04.034

Editorial

Mintz, HP, Dosanjh, ARS, Parsons, H, Sydes, M, Bryan, RT, James, ND & Patel, P 2023, 'Making administrative healthcare systems clinical data the future of clinical trials: lessons from BladderPath', BMJ Oncology, vol. 2, no. 1, e000038. https://doi.org/10.1136/bmjonc-2023-000038

Review article

Nanton, V, Bryan, R, Pope, A, Hughes, A, Jefferson, K, Catto, J, Knight, A, Gallagher, J, Mintz, H, Pirrie, S, Liu, W, Young, A, Patel, P & James, N 2023, 'Boosting and broadening recruitment to UK cancer trials: towards a blueprint for action', BMJ Oncology, vol. 2, no. 1, e000092. https://doi.org/10.1136/bmjonc-2023-000092

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Expertise

Urology