Dr Vasileios Panagiotis Lenis PhD, FHEA

Dr Vasileios Lenis

Department of Cancer and Genomic Sciences
Associate Professor in Bioinformatics and Health Data Science Education

Contact details

Email
v.p.lenis@bham.ac.uk
View my research portal
Address
Department of Cancer and Genomic Sciences
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

My research interests lie in a wide range of fields in biological and biomedical sciences, from comparative genomics and evolutionary studies to neuroscience research and personalised medicine. I am mainly focused on the study of the molecular mechanism of neuropsychological disorders and brain tumours. My aim is the understanding of the molecular origins of the diseases and the development of novel methods for the diagnosis and the prognosis, as the design of more targeted treatment strategies.

Currently, I am focused on teaching in the MSc Health Data Science (HDS) and regularly I am teaching in workshops related to bioinformatics and health data analysis in several Universities across the UK and other European countries.

Qualifications

  • PgCert Learning and Teaching in Higher Education (LTHPGC), Teesside University, UK.
  • PhD in Bioinformatics, Aberystwyth University, UK.
  • M.Sc. in Applied Informatics, University of Macedonia, Greece.
  • B.Sc. in Computer Science, Hellenic Open University, Greece.

Biography

Dr Lenis has studies Computer Science and Applied informatics in the UK and Greece and received his PhD in Genomics and Bioinformatics from the University of Aberystwyth (UK). He has held a number of positions in Aberystwyth, Plymouth and Teesside University before joining the University of Birmingham (UK).

Teaching

Clinical Science MSci Integrated degree

  • ICS Clinical Bioinformatics and Statistics

MSc Health Data Science

  • Foundations of Computing Practices in Health Data Science
  • Interdisciplinary Health Data Research Project

MSc Health Data Science (Dubai)

  • Foundations of Computing Practices in Health Data Science

Postgraduate supervision

I am always looking for interested and motivated PhD students within my preferred research areas. Please contact me directly via email. 

Research

My main research area involves methods originated from systems biology, NGS and “omics” technologies, large multi-dimensional data integration and interpretation, and clinical informatics.

ResearchGate Profile

Other activities

  • Software/Data Carpentry Instructor
  • Data Stewardship Fellow, Elixir

Publications

Quesnel, A, Martin, LD, Tarzi, C, Lenis, VP, Coles, N, Islam, M, Angione, C, Outeiro, TF, Khundakar, AA & Filippou, PS 2024, 'Uncovering potential diagnostic and pathophysiological roles of α‐synuclein and DJ‐1 in melanoma', Cancer Medicine, vol. 13, no. 1, e6900. https://doi.org/10.1002/cam4.6900 

Smulders-Srinivasan, TK, Jenkinson, SE, Brown, LJ, Lenis, VP & Bass, R 2023, 'PDIA6 and Maspin in Prostate Cancer', Anticancer research, vol. 43, no. 12, pp. 5331-5340. https://doi.org/10.21873/anticanres.16736                                                 

Tounsi, WA, Lenis, VP, Tammi, SM, Sainio, S, Haimila, K, Avent, ND & Madgett, TE 2022, 'Rh Blood Group D Antigen Genotyping Using a Portable Nanopore-based Sequencing Device: Proof of Principle', Clinical Chemistry, vol. 68, no. 9, pp. 1196–1201. https://doi.org/10.1093/clinchem/hvac075

Sweet-Jones, J, Lenis, VP, Yurchenko, AA, Yudin, NS, Swain, M & Larkin, DM 2021, 'Genotyping and Whole-Genome Resequencing of Welsh Sheep Breeds Reveal Candidate Genes and Variants for Adaptation to Local Environment and Socioeconomic Traits', Frontiers in Genetics, vol. 12, 612492. https://doi.org/10.3389/fgene.2021.612492 

Craven, HM, Bonsignore, R, Lenis, VP, Santi, N, Berrar, D, Swain, M, Whiteland, H, Casini, A & Hoffmann, KF 2021, 'Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni', PLoS Neglected Tropical Diseases, vol. 15, no. 2, e0008770. https://doi.org/10.1371/journal.pntd.0008770 

Dunn, J, Lenis, VP, Hilton, DA, Warta, R, Herold-Mende, C, Hanemann, CO & Futschik, M 2020, 'Integration and Comparison of Transcriptomic and Proteomic Data for Meningioma', Cancers. https://doi.org/10.3390/cancers12113270 

Attardo, GM, Abd-Alla, AMM, Acosta-Serrano, A, Allen, JE, Bateta, R, Benoit, JB, Bourtzis, K, Caers, J, Caljon, G, Christensen, MB, Farrow, DW, Friedrich, M, Hua-Van, A,  Jennings, EC, Larkin, DM, Lawson, D, Lehane, MJ, Lenis, VP, Lowy-Gallego, E, Macharia, RW, Malacrida, AR, Marco, HG, Masiga, D, Maslen, GL, Matetovici, I, Meisel, RP, Meki, I, Michalkova, V, Miller, WJ, Minx, P, Mireji, PO, Ometto, L, Parker, AG, Rio, R, Rose, C, Rosendale, AJ, Rota-Stabelli, O, Savini, G, Schoofs, L, Scolari, F, Swain, MT, Takáč, P, Tomlinson, C, Tsiamis, G, Van Den Abbeele, J, Vigneron, A, Wang, J, Warren, WC, Waterhouse, RM & Weirauch, MT 2019, 'Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes', Genome Biology, vol. 20, no. 1, 187. https://doi.org/10.1186/s13059-019-1768-2 

Lenis, VPE, Swain, M & Larkin, DM 2018, 'G-Anchor: a novel approach for whole-genome comparative mapping utilizing evolutionary conserved DNA sequences', GigaScience. https://doi.org/10.1093/gigascience/giy017 

Damas, J, O'Connor, R, Farré, M, Lenis, VPE, Martell, HJ, Mandawala, A, Fowler, K, Joseph, S, Swain, MT, Griffin, DK & Larkin, DM 2017, 'Upgrading short-read animal genome assemblies to chromosome level using comparative genomics and a universal probe set', Genome Research. https://doi.org/10.1101/gr.213660.116 

Skujina, I, McMahon, R, Lenis, VE, Gkoutos, GV & Hegarty, M 2016, 'Duplication of the mitochondrial control region is associated with increased longevity in birds', Aging. https://doi.org/10.18632/aging.101012

View all publications in research portal