Recent publications
Article
Innovative Therapies for Children with Cancer (ITCC) Consortium & European Association for Neuroblastoma Research (SIOPEN) 2024, 'Bevacizumab, Irinotecan, or Topotecan Added to Temozolomide for Children With Relapsed and Refractory Neuroblastoma: Results of the ITCC-SIOPEN BEACON-Neuroblastoma Trial', Journal of Clinical Oncology. https://doi.org/10.1200/JCO.23.00458
Chisholm, J, Mandeville, H, Adams, M, Minard-Collin, V, Rogers, T, Kelsey, A, Shipley, J, van Rijn, RR, de Vries, I, van Ewijk, R, de Keizer, B, Gatz, SA, Casanova, M, Hjalgrim, LL, Firth, C, Wheatley, K, Kearns, P, Liu, W, Kirkham, A, Rees, H, Bisogno, G, Wasti, A, Wakeling, S, Heenen, D, Tweddle, DA, Merks, JHM, Jenney, M & Heymann, D (ed.) 2024, 'Frontline and Relapsed Rhabdomyosarcoma (FAR-RMS) Clinical Trial: A Report from the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)', Cancers, vol. 16, no. 5, 998. https://doi.org/10.3390/cancers16050998
Perry, TA, Masand, N, Vrzalikova, K, Pugh, M, Wei, W, Hollows, R, Bouchalova, K, Nohtani, M, Fennell, E, Bouchal, J, Kearns, P & Murray, PG 2024, 'The Oncogenic Lipid Sphingosine-1-Phosphate Impedes the Phagocytosis of Tumor Cells by M1 Macrophages in Diffuse Large B Cell Lymphoma', Cancers, vol. 16, no. 3, 574. https://doi.org/10.3390/cancers16030574
Janssens, GO, Timmermann, B, Laprie, A, Mandeville, H, Padovani, L, Chargari, C, Kearns, P, Kozhaeva, O, Kameric, L, Kienesberger, A, van Rossum, PSN, Boterberg, T, Lievens, Y & Vassal, G 2024, 'The organization of care in pediatric radiotherapy across SIOP Europe affiliated centers: A multicenter survey in the framework of the 'Joint Action on Rare Cancers' project', Radiotherapy & Oncology, vol. 191, 110075. https://doi.org/10.1016/j.radonc.2023.110075
Experimental Cancer Medicine Centres (ECMC) CID trials working group, Blagden, SP, Yu, L-M, Ellis, S, Hughes, H, Shaaban, A, Fennelly-Barnwell, J, Lythgoe, MP, Cooper, AM, Maignen, FM, Buckland, SW, Kearns, PR & Brown, LC 2023, 'Additional consensus recommendations for conducting complex innovative trials of oncology agents: a post-pandemic perspective', British Journal of Cancer, vol. 128, no. 3, pp. 474-477. https://doi.org/10.1038/s41416-022-02051-7
de Rojas, T, Kearns, P, Blanc, P, Skolnik, J, Fox, E, Knox, L, Rousseau, R, Doz, F, Bird, N, Pearson, AJ & Vassal, G 2023, 'Changing incentives to ACCELERATE drug development for paediatric cancer', Cancer Medicine, vol. 12, no. 7, pp. 8825-8837. https://doi.org/10.1002/cam4.5627
Moreno, L, DuBois, SG, Glade Bender, J, Mauguen, A, Bird, N, Buenger, V, Casanova, M, Doz, F, Fox, E, Gore, L, Hawkins, DS, Izraeli, S, Jones, DTW, Kearns, PR, Molenaar, JJ, Nysom, K, Pfister, S, Reaman, G, Smith, M, Weigel, B, Vassal, G, Zwaan, CM, Paoletti, X, Iasonos, A & Pearson, ADJ 2023, 'Combination Early-Phase Trials of Anticancer Agents in Children and Adolescents', Journal of Clinical Oncology . https://doi.org/10.1200/JCO.22.02430
Retzer, A, Baddeley, E, Sivell, S, Scott, H, Nelson, A, Bulbeck, H, Seddon, K, Grant, R, Adams, R, Watts, C, Aiyegbusi, OL, Kearns, P, Cruz Rivera, S, Dirven, L, Calvert, M & Byrne, A 2023, 'Development of a core outcome set for use in adult primary glioma phase III interventional trials: A mixed methods study', Neuro-oncology advances. https://doi.org/10.1093/noajnl/vdad096
PITCH Consortium, CONSENSUS & OCTAVE Collaborative Group 2023, 'SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease', Nature Medicine. https://doi.org/10.1038/s41591-023-02414-4
Aggarwal, A, Choudhury, A, Fearnhead, NS, Kearns, P, Kirby, A, Lawler, M, Quinlan, S, Palmieri, C, Roques, T, Simcock, R, Walter, FM, Price, P & Sullivan, R 2023, 'The future of cancer care in the UK—time for a radical and sustainable National Cancer Plan', The Lancet Oncology. https://doi.org/10.1016/S1470-2045(23)00511-9
Millen, GC, Arnold, R, Cazier, J-B, Curley, H, Feltbower, R, Gamble, A, Glaser, A, Grundy, RG, Kirton, L, Lee, LYW, McCabe, MG, Palles, C, Phillips, B, Stiller, CA, Varnai, C & Kearns, P 2022, 'COVID-19 in children with haematological malignancies', Archives of Disease in Childhood, vol. 107, no. 2, pp. 186-188. https://doi.org/10.1136/archdischild-2021-322062
Retzer, A, Sivell, S, Scott, H, Nelson, A, Bulbeck, H, Seddon, K, Grant, R, Adams, R, Watts, C, Aiyegbusi, OL, Kearns, P, Cruz Rivera, S, Dirven, L, Baddeley, E, Calvert, M & Byrne, A 2022, 'Development of a core outcome set and identification of patient-reportable outcomes for primary brain tumour trials: protocol for the COBra study', BMJ open, vol. 12, no. 9, e057712, pp. e057712. https://doi.org/10.1136/bmjopen-2021-057712
Comment/debate
Wilson, JS, Main, C, Thorp, N, Taylor, RE, Majothi, S, Kearns, PR, English, M, Dandapani, M, Phillips, R, Wheatley, K & Pizer, B 2024, 'Correction to: The effectiveness and safety of proton beam radiation therapy in children and young adults with Central Nervous System (CNS) tumours: a systematic review', Journal of Neuro-Oncology. https://doi.org/10.1007/s11060-024-04612-7
Letter
O’Connor, D, Joy, M, Enshaei, A, Kirkwood, A, Kearns, PR, Samarasinghe, S, Moppett, J, Moorman, AV & Vora, A 2023, 'Cranial radiotherapy has minimal benefit in children with central nervous system involvement in T-ALL', Blood Advances. https://doi.org/10.1182/bloodadvances.2023011267
Review article
Wilson, JS, Main, C, Thorp, N, Taylor, RE, Majothi, S, Kearns, PR, English, M, Dandapani, M, Phillips, R, Wheatley, K & Pizer, B 2024, 'The effectiveness and safety of proton beam radiation therapy in children and young adults with Central Nervous System (CNS) tumours: a systematic review', Journal of Neuro-Oncology. https://doi.org/10.1007/s11060-023-04510-4
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