Recent publications
Article
Srinivasan, V, Homer, V, Barton, D, Clutterbuck-James, A, Jenkins, S, Potter, C, Brock, K, Logan, A, Smith, D, Bruce, L, Nagy, Z & Bach, SP 2024, 'A low molecular weight dextran sulphate, ILB ®, for the treatment of amyotrophic lateral sclerosis (ALS): An open-label, single-arm, single-centre, phase II trial', PLoS ONE, vol. 19, no. 7, e0291285. https://doi.org/10.1371/journal.pone.0291285
Thaller, M, Homer, V, Abbott, S, Hazlehurst, J, Mollan, SP & Sinclair, AJ 2024, 'Does a Healthy Weight Body Mass Index at Onset of Idiopathic Intracranial Hypertension Change the Outcomes? A United Kingdom Prospective Cohort Study', Neuro-Ophthalmology. https://doi.org/10.1080/01658107.2024.2341775
Hirschfield, G, Arndtz, K, Kirkham, A, Chen, Y-Y, Fox, R, Rowe, A, Douglas-Pugh, J, Thorburn, D, Barnes, E, Aithal, GP, Hull, D, Bhandal, K, Olsen, K, Woodward, P, Lax, S, Newsome, P, Smith, D, Kallio, A, Adams, D, Homer, V & Weston, C 2024, 'Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: open-label, multi-centre, single arm, phase II trial', Hepatology Communications, vol. 8, no. 5, e0426. https://doi.org/10.1097/HC9.0000000000000426
Thaller, M, Homer, V, Mollan, S & Sinclair, A 2023, 'Asymptomatic idiopathic intracranial hypertension: Prevalence and prognosis', Clinical and Experimental Ophthalmology. https://doi.org/10.1111/ceo.14256
Loke, J, Upasani, V, Gaskell, C, Fox, S, Fletcher, R, Thomas, C, Hopkins, L, Kumari, A, Tang, T, Yafai, E, Boucher, R, Homer, V, Toth, A, Chan, YLT, Randall, K, Rider, T, O'nions, J, Drew, V, Pillai, A, Dungarwalla, M, Murray, D, Khan, A, Wandroo, F, Moore, S, Krishnamurthy, P, Huang, YJ, Knapper, S, Byrne, J, Zhao, R, Craddock, C, Parry, H, Moss, P, Stanworth, SJ & Lowe, DM 2023, 'Defective T‐cell response to COVID‐19 vaccination in acute myeloid leukaemia and myelodysplastic syndromes', British Journal of Haematology, vol. 202, no. 3, pp. 498-503. https://doi.org/10.1111/bjh.18894
Englert, S, Mercier, F, Pilling, EA, Homer, V, Habermehl, C, Zimmermann, S & Kan-Dobrosky, N 2023, 'Defining estimands for efficacy assessment in single arm phase 1b or phase 2 clinical trials in oncology early development', Pharmaceutical Statistics, vol. 22, no. 5, pp. 921-937. https://doi.org/10.1002/pst.2319
Hyder, YF, Homer, V, Thaller, M, Byrne, M, Tsermoulas, G, Piccus, R, Mollan, SP & Sinclair, AJ 2023, 'Defining the Phenotype and Prognosis of People With Idiopathic Intracranial Hypertension After Cerebrospinal Fluid Diversion Surgery', American Journal of Ophthalmology, vol. 250, pp. 70-81. https://doi.org/10.1016/j.ajo.2023.01.016
Thaller, M, Homer, V, Mollan, SP & Sinclair, AJ 2023, 'Disease Course and Long-term Outcomes in Pregnant Women With Idiopathic Intracranial Hypertension: The IIH Prospective Maternal Health Study', Neurology, vol. 100, no. 15, pp. E1598-E1610. https://doi.org/10.1212/WNL.0000000000206854
Imran, R, Hassouna, T, Sur, G, Casey, A, Homer, V, Barton, D, Brock, K, Altarrah, K & Moiemen, N 2023, 'Efficacy and optimal dose of acetic acid to treat colonised burns woundss: protocol for a pilot randomised controlled trial', BMJ open, vol. 13, no. 9, e058006. https://doi.org/10.1136/bmjopen-2021-058006
Mercier, F, Homer, V, Geng, J, Zhang, H, Englert, S, Kan-Dobrosky, N & Victor, A 2023, 'Estimands in oncology early clinical development: Assessing the impact of intercurrent events on the dose-toxicity relationship', Statistics in Biopharmaceutical Research. https://doi.org/10.1080/19466315.2023.2296648
Thaller, M, Homer, V, Sassani, M, Mollan, SP & Sinclair, AJ 2023, 'Longitudinal prospective cohort study evaluating prognosis in idiopathic intracranial hypertension patients with and without comorbid polycystic ovarian syndrome', Eye (London, England). https://doi.org/10.1038/s41433-023-02569-x
Bailey, S, André, N, Gandola, L, Massimino, M, Wheatley, K, Gates, S, Homer, V, Rutkowski, S & Clifford, S 2022, 'Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial', Cancers, vol. 14, no. 2, 374. https://doi.org/10.3390/cancers14020374
Homer, V, Yap, C, Bond, S, Holmes, J, Stocken, D, Walker, K, Robinson, EJ, Wheeler, G, Brown, S, Hinsley, S, Schipper, M, Weir, CJ, Rantell, K, Prior, T, Yu, L-M, Kirkpatrick, J, Bedding, A, Gamble, C & Gaunt, P 2022, 'Early phase clinical trials extension to guidelines for the content of statistical analysis plans', BMJ, vol. 376, e068177. https://doi.org/10.1136/bmj-2021-068177
Arndtz, K, Chen, YY, Rowe, A, Homer, V, Kirkham, A, Douglas-Pugh, J, Slade, D, Thorburn, D, Barnes, E, Aithal, G, Newsome, P, Smith, D, Adams, D, Weston, C & Hirschfield, G 2022, 'Monoclonal antibody BTT1023 targeting vascular adhesion protein 1 for treating primary sclerosing cholangitis: BUTEO single-arm Phase II trial', Efficacy and Mechanism Evaluation, vol. 9, no. 1. https://doi.org/10.3310/ZPNF4670
Comment/debate
Bailey, S, André, N, Gandola, L, Massimino, M, Wheatley, K, Gates, S, Homer, V, Rutkowski, S & Clifford, SC 2024, 'Correction: Bailey et al. Clinical Trials in High-Risk Medulloblastoma: Evolution of the SIOP-Europe HR-MB Trial. Cancers 2022, 14, 374', Cancers, vol. 16, no. 6, 1084. https://doi.org/10.3390/cancers16061084
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