First author primary research papers
Apps JR , Maycock S, Ellison DW, Jaspan T, Ritzmann TA, Macarthur D, Malluci C, Wheatley K, Veal GJ, Grundy RG, Picton S, Phase II Study of Intravenous Etoposide in Patients with Relapsed Ependymoma (CNS 2001 04), Neuro-Oncology Advances, 2022, 13;4(1):vdac053. doi: 10.1093/noajnl/vdac053.
Apps JR, Stache C, Gonzalez-Meljem JM, Gutteridge A, Chalker J, Jacques TS, Forshew T, Holsken A, Martinez-Barbera JP, CTNNB1 mutations are clonal in adamantinomatous craniopharyngioma, Neuropathology and Applied Neurobiology, 2020, 46, 510-514
Apps JR, Hutchinson C, Learning from cases: Analysis of two cases of craniopharyngioma from the 19th to the 21st centuries, F1000 research, 2019, 8, 1544
Apps JR, Carreno G, Gonzalez-Meljem JM, Haston S, Guiho R, Cooper JE, Manshaei S, Jani N, Hölsken A, Pettorini B, Beynon RJ, Simpson DM, Fraser HC, Hong Y, Hallang S, Stone TJ, Virasami A, Donson AM, Jones D, Aquilina K, Spoudeas H, Joshi AR, Grundy R, Storer LCD, Korbonits M, Hilton DA, Tossell K, Thavaraj S, Ungless MA, Gil J, Buslei R, Hankinson T, Hargrave D, Goding C, Andoniadou CL Brogan P, Jacques T, Williams HJ, Martinez-Barbera JP, Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target, Acta Neuropathol. 2018 135(5):757-777
Vujanić GM*, Apps JR*, Moroz V, Ceroni F, Williams RD, Sebire NJ, Pritchard-Jones K, Nephrogenic rests in Wilms tumors treated with preoperative chemotherapy: The UK SIOP Wilms Tumor 2001 Trial experience., Pediatr Blood Cancer. 2017, Apr 6.
Cresswell G*, Apps JR*, Chagtai T, Mifsud B, Bentley CC, M Mascietto, SD Popov, M Weeks, OE Olsen, NJ Sebire, K Pritchard-Jones, NM Luscombe, RD Williams, W Mifsud, Intra-tumour genetic heterogeneity in Wilms’ tumour: clonal evolution and clinical implication. EBiomedicine, 2016, 9, 120-9
Apps JR*, Hutchinson JC*, Arthurs OJ, Virasami A, Joshi A, Zeller-Plumhoff B, Moulding D, Jacques TS, Sebire NJ, Martinez-Barbera JP, Imaging Invasion: Micro-CT imaging of adamantinomatous craniopharyngioma highlights cell type specific spatial relationships of tissue invasion, Acta Neuro Comms, 2016, 4, 57
Apps JR, Williams C, McGuinness A, Gabbie S, Sutcliffe AG, Stabbing and safeguarding in children and young people: a Pan-London service evaluation and audit, J R Soc Med Short Reports 2013, 5 (4) 1-7
Apps JR, Hasan F, Campus O, Behjati S, Jacques T, Sebire N, Anderson J, The immune environment of paediatric solid malignancies; evidence from an immunohistochemical study of clinical cases, Fetal and Pediatric Pathology, 2013, 32 (4) 298-307
NB: * indicates joint first authorship/equal contribution
Contributing author primary research papers
Pozzi S, Bowling S, Apps J, Brickman JM, Rodriguez TA, Martinez-Barbera JP. Genetic Deletion of Hesx1 Promotes Exit from the Pluripotent State and Impairs Developmental Diapause, Stem Cell Reports. 2019 Dec 10;13(6):970-979.
Carreno G, Boult JKR, Apps JR, Gonzalez-Meljem JM, Haston S, Guiho R, Stache C, Danielson LS, Koers A, Smith LS, Virasami A, Panousopoulos L, Buchfelder M, Jacques TS, Chesler L, Robinson S, Martinez-Barbera JP, SHH Pathway inhibition is protumorigenic in adamantinomatous craniopharyngioma, Endocr Related Cancer, 2019, Jan 1.
Xekouki P, Lodge EJ, Matschke J, Santambrogio A, Apps JR, Sharif A, Jacques TS, Aylwin S, Prevot V, Li R, Flitsch J, Bornstein SR, Theodoropoulou M, Andoniadou C., Non-secreting pituitary tumours characterised by enhanced expression of YAP/TAZ, Endocr Relat Cancer. 2018 Aug 23. pii: ERC-18-0330. doi: 10.1530/ERC-18-0330
Gonzalez-Meljem MJ, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Martinez-Barbera JP, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma, Nat Commun. 2017 Nov 28;8(1):1819. doi: 10.1038/s41467-017-01992-5.
Donson A, Apps, J, Griesinger AM, Amani V, Witt DA, Anderson RCE, Niazi TN, Grant G, Souweidane M, Johnston JM, Jackson EM, Kleinschmidt-DeMasters BK, Handler MH, Tan A, Gore L, Virasami A, Gonzalez-Meljem JM, Jacques TS, Martinez-Barbera JP, Foreman NK, Hankinson TC., Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma, Journal of Neuropathology & Experimental Neurology, 2017 76(9): 779–788
Carreno G, Apps JR, Lodge EJ, Panousopoulos L, Haston S, Gonzalez-Meljem JM, Hahn H, Andoniadou CL, Martinez-Barbera JP, Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors, Development. 2017 Sep 15 ;144(18):3289-3302.
Haston S, Pozzi S, Carreno G, Manshei S, Panousopoulos L, Perez-Meljem JM, Apps JR, Virasami A, Thavaraj S, Gutteridge A, Forshew T, Marais R, Brandner S, Jacques T, Andoniadou C, Martinez-Barbera JP, MAPK pathway activation in the embryonic pituitary results in stem cell compartment expansion, differentiation defects and provides insights into the pathogenesis of papillary craniopharnygioma, Development. 2017 Jun 15;144(12):2141-2152.
Boult JK, Apps JR, Holsken A, Hutchinson JC, Carreno G, Danielson LD, Smith LM, Baeurerle T, Buslei R, Buchfelder M, Virasami A, Koers A, Arthurs O, Jacques TS, Chesler L, Martinez-Barbera JP, Robinson S, Preclinical transgenic and patient derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharnygioma, Brain Pathology, Brain Pathol. 2017 May 8. doi: 10.1111/bpa.12525.
Poulogiannis G, McIntyre RE, Dimitriadi M, Apps JR, Wilson GH, Ichimura K, Luo F, Cantley LC, Wyllie AJ, Adams DJ, Arends MJ, PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in APC mice, Proc Natl Acad Sci U S A2010, 107 (34) 15145-50
Case Reports
Apps, JR, Gagen R, Neumann E, Solanki G, English M, A thirteen year patient journey of infant giant clival chordoma: Case report and literature review, Child Nerv Syst.Accepted for publication Nov 2022.
Reviews
Apps JR, Muller HL, Hankinson TC, Yock TI, Martinez-Barbera JP, An Update on Craniopharyngioma, Endocrine Reviews, Accepted October 2022.
Gonzalez-Meljem MJ*, Apps JR*, Fraser H, Martinez-Barbera JP, Paracrine roles of cellular senescence in promoting tumourigenesis, British Journal of Cancer, 2018 May;118(10):1283-1288.
Apps JR, Martinez-Barbera JP, Genetically engineered mouse models of craniopharyngioma: an opportunity for therapy development and understanding of tumor biology, Brain Pathology, 2017,27(30) 364-369
Apps JR, Martinez-Barbera JP, Molecular pathology of adamantinomatous craniopharyngioma: review and opportunities for practice, Neurosurg Focus, 2016, 41(6), E4
Szychot E, Apps J, Pritchard-Jones K, Wilms tumour: biology, diagnosis and treatment, Transl Pediatr 2014, 3 (1) 12-24
Apps JR, Flint JD, Wacogne I, Archimedes: Does anti-reflux therapy improve symptoms with laryngomalacia, Archives of Disease in Childhood, 2012, 97:385-7
Tickner N, Apps JR, Keady S, Sutlcliffe AG, Pharmacy Update: Drugs used in the treatment of dystonia and spasticity in children, Archives of Diseases in Childhood, Education and Practice Edition, 2012, 97(6) 230-5
Apps JR, Beattie RM, Easily Missed? Cow’s Milk Allergy in Children, BMJ, 2009, 339 343-346
Other papers
Apps JR, Martinez-Barbera, JP, Editorial, A promising future for hypothalamic dysfunction in craniopharyngioma, Neuro-Oncol, 2022 Dec 27;noac284. doi: 10.1093/neuonc/noac284.
Apps JR, Research in practice: fitting it together, Archives of Disease in Childhood - Education and Practice, 2020, doi: 10.1136/archdischild-2019-318689
Brown CC, Apps JR, Davies G, Ware N, Fisher J, Winyard P, Making your way as an academic trainee Archives of Diseases in Childhood, Education and Practice Edition, 2014, 99 (1) 13-14
Apps J, Bossley C, Picket: Lansoprazole for children with poorly controlled asthma, Archives of Diseases in Childhood, Education and Practice Edition, 2013, 98(5) 199-200.
Brown CC, Apps J, Winyard PJ, Letter: The next generation of academic paediatricians, Lancet, 2013, 382 (9886) 28
Book chapters
JR Apps, JP Martinez-Barbera, Mouse Models of Craniopharyngioma, Book Title: Adult craniopharyngiomas – differences and lessons from paediatrics, Editors, Emmanuel Jouanneau, Gérald Raverot, Springer publishing. ISBN 978-3-030-41175-6 ISBN 978-3-030-41176-3 (eBook)
JR Apps, JP Martinez-Barbera, Pathophysiology and genetics in craniopharyngioma, Book Title: Pituitary Tumors: A Comprehensive and Interdisciplinary Approach. Editor, Juergen Honneger, Elsevier, ISBN 9780128199497, currently in proof stage
JR Apps, E Butrous, K Sugand, M Berry, Getting Ahead, Book Title: Oxford Handbook for Medical School, Editors Kapil Sugand, Miriam Berry, Imran Yusuf, Aisha Janjua, Chris Bird, Oxford University Press, 2019, ISBN: 978-0-190968190-7
JR Apps, AG Sutcliffe, Chapter: Paediatric Outcomes of Artificial Reproductive Technologies: Lessons from Research, I Book Title: In Vitro Fertilisation, Novapublishers, 2011, ISBN: 978-1-61209-961-3
T Turner-Stokes and JR Apps, Directly Observed Procedures (DOPS), Shakur R (Editor), Darzi A, Catto G, Book Title: The Essential Clinical Handbook for the Foundation Programme: A Comprehensive Guide for Foundation Doctors on How to Achieve Your Competencies. Developmedica, 2010, ISBN: 1906839093
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