Professor Thomas Pinkney MBChB, MD, MMedEd, FRCS

Professor Thomas Pinkney

Department of Applied Health Sciences
George Drexler & Royal College of Surgeons Chair of Surgical Trials
Honorary Consultant General and Colorectal Surgeon

Contact details

Address
Birmingham Clinical Trials Unit
Public Health Building
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Professor Thomas Pinkney received his Medical Degree from the University of Birmingham in 2000. He was appointed as Senior Lecturer in Surgery in 2012 and awarded an honorary consultant appointment at the University Hospitals Birmingham at the same time.  In 2019 Tom was promoted to Professor as George Drexler and Royal College of Surgeons Chair of Surgical Trials at the University of Birmingham.

Tom is Director of Clinical Research at the Royal College of Surgeons of England and an NIHR Senior Investigator. He is Director of the Birmingham Surgical Trials Consortium (BiSTC) and the Birmingham Centre for Observational and Prospective Studies (BiCOPS).  Tom Chairs  the research committee of the European Society of Coloproctology [ESCP] and the Multidisciplinary Clinical Committee of the Association of Coloproctology [ACPGBI] . He is also Health and Care Research Director for NIHR Regional Research Delivery Network (RRDN) West Midlands.

Tom's research interests are predominantly in clinical and translational research in inflammatory bowel disease and surgical site infection. As a founding member of the West Midlands Research Collaborative, he maintains an interest in development of trainee-led clinical trials in surgery. He previously sat on the NIHR Health Technology Assessment (HTA) CET Board and the NIHR Research for Patient Benefit (RfPB) West Midlands Panels.

ROSSINI-Platform trial
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Qualifications

  • MD, University of Birmingham, 2017
  • MMedEd, University of Warwick, 2011
  • FRCS, Royal College of Surgeons, 2010
  • MBChB, University Of Birmingham, 2000

Teaching

  • Fixed undergraduate (clinical) tutorial sessions each week and teaches students during his outpatient, endoscopy and theatre sessions
  • Lectures medical students, as well as providing small group teaching sessions
  • Surgical lead, 5th year MBChB programme
  • Runs regular clinical research methodology training days for West Midlands core and higher surgical trainees
  • Academic Training Programme Director, Health Education England (West Midlands)
  • Clinical Academic Training Committee Lead, Surgery

Postgraduate supervision

  • Samerah Saeed, Clinical Research Fellow (2023-ongoing)
  • Sue Blackwell, PhD Student (2022-ongoing)
  • Kayani Kayani, Academic Clinical Fellow (2021-2024)
  • Daniel Osei-Bardom, Academic Clinical Fellow (2018-2021)
  • Elizabeth Li, Clinical Research Fellow (PhD) (2017-2020)
  • Yashawi Sinha, Academic Clinical Fellow (2017-2020)
  • James Glasbey, Academic Clinical Fellow (2016-2019)
  • Muhammad Atif, Academic Clinical Fellow (2015-2018)
  • Dmitri Nepogodiev, Academic Clinical Fellow (2014-2017)

Research

  • Birmingham Surgical Trials Consortium

Tom is Director of Birmingham Surgical Trials Consortium (BiSTC). The BiSTC is funded by the Royal College of Surgeons of England to develop new surgical clinical trials, widening participation in trials and train the trialists of the future.

  • Birmingham Centre for Observational and Prospective Studies 

This new unit was established in 2019 and Tom co-leads it with Dr Laura Magill. The Birmingham Centre for Observational and Prospective Studies (BiCOPS) aims to provide centralised guidance and practical support to groups of researchers coming together to undertake non-randomised prospective research, including large scale national and international clinical snapshot audits and cohort studies.

  • Clinical Research - Grants

In the past 10 years Tom has been awarded £18.54M as the chief investigator of 7 major NIHR portfolio surgical projects to benefit patients through improved surgical care; 5 are multicentre RCTs and two for the development of a surgical device. He is also a co-applicant on 23 further grants totalling £58.72M.

  • Inflammatory Bowel Disease

Tom’s specialist clinical interest is in inflammatory bowel disease (IBD). He was Chief Investigator of the NIHR Research for Public Benefit (RfPB) funded ACCURE-UK feasibility trial. This has been followed more recently with the NIHR EME-funded ACCURE-UK 2 trial, which is the UK arm of an international RCT being conducted alongside colleagues at Academisch Medisch Centrum, Amsterdam. ACCURE-UK 2 is exploring the clinical effectiveness of therapeutic appendicectomy to reduce disease activity in Ulcerative Colitis.  

In addition to this clinical research, Tom previously chaired the Inflammatory Bowel Disease sub-committee of the Association of Coloproctology of GB&I (ACPGBI) and the National Inflammatory Bowel Disease Clinical Advisory Group of the Royal College of Surgeons & ACPGBI. He has been an invited clinician stakeholder in a variety of clinical guideline update groups, both in the UK and Europe.

  • Surgical Site Infection (SSI)

When a senior registrar, Tom was the Chief Investigator of the ROSSINI (Reduction of Surgical Site Infection using a Novel Intervention, 2008-13) trial He has been involved in many other SSI trials including Bluebelle, FALCON, CHEETAH and MARLIN over the years and directly led the SUNRRISE (senior applicant) and ROSSINI2 (chief investigator) trials. ROSSINI 2 was the first multi-arm, multi-stage (MAMS) interventional trial funded in surgery and in its first iteration recruited over 5,300 patient from 53 hospitals. It has recently been awarded a further £1.1M to fund an extension phase which will explore the clinical effectiveness of two different interventions in abdominal surgery, via the existing delivery network.

This led on to the multi-speciality ROSSINI-Platform trial, which was funded in 2024 and is the largest interventional trial funded in surgery at £10.24M and nearly 26,000 patients. Tom sat on the NICE Guidelines Committee (NG125) for SSI.

  • International research networks

Tom is chair of the European Society of Coloproctology (ESCP) Research Committee and previously led the Cohort Studies Subcommittee. He has delivered multiple international studies and audits, which have together collected outcomes data from over 20,000 individual patients undergoing operations in over 400 surgical units across 54 countries. He sits on the executive of the NIHR Global Health Research Unit on Global Surgery which is based in Birmingham.

  • NIHR Portfolio trials

Tom is one of the three Health and Care Research Directors within the newly formed Regional Research Delivery Network (RRDN) for the West Midlands. He was previously National Specialty Lead [NSL] for surgery within the NIHR Clinical Research Network.

In terms of external roles, He chairs two NIHR trial steering committees (TSCs), sits on a further six TSCs and two data monitoring committees.

  • Trainee-centric research collaboratives

Research collaboratives: After helping found the West Midlands Research Collaborative, Tom has have spoken and published extensively on the collaborative research model, and helped many new collaboratives to establish in multiple specialities at all levels, in the UK and overseas.

The impact of wound-edge protection devices on surgical site infection (ROSSINI Trial)

Other activities

External positions currently held

 International:
  • Chair, Research Committee, European Society of Coloproctology (ESCP)
  • Past-Chair, Cohort Studies sub-committee, European Society of Coloproctology (ESCP)
  • Executive Committee of the NIHR Global Health Research Unit on Global Surgery (GSU)
  • Executive Committee & Council of the European Society of Coloproctology (ESCP)
 National:
  • Director of Clinical Research, Royal College of Surgeons of England
  • Chair, Multidisciplinary Clinical Committee, Association of Coloproctology of GB&I (ACPGBI)
  • Executive Committee & Council of the Association of Coloproctology of GB&I (ACPGBI)
  • Member, National Institute for Health and Care Excellence (NICE) Surgical Site Infection Guidelines committee
  • Member, National Institute for Health and Care Excellence (NICE) Medical Technologies Advisory Committee (MTAC)
  • Board member & co-founder, National Wounds Research Network (WreN)
Regional:
  • Director, Birmingham Surgical Trials Consortium (BiSTC)
  • Director, Birmingham Centre for Observational and Prospective Studies (BiCOPS)
  • Health & Care Research Director, NIHR Regional Research Delivery Network West Midlands
  • Academic Training Programme Director [TPD], School of Surgery, Health Education England (WM)

External positions previously held

National:
  • NIHR Clinical Research Network (CRN) National Specialty Lead for Surgery
  • Board member, NIHR Health Technology Assessment (HTA) Clinical Trials and Evaluations Board
  • Chair, Inflammatory Bowel Disease sub-committee, Association of Coloproctology of GB&I (ACPGBI)
  • Associate Editor, Colorectal Disease journal
  • Member, Research & Audit committee, Association of Coloproctology of GB&I (ACPGBI)
  • Member, National Cancer Research Institute (NCRI) Colorectal Cancer Clinical Studies Group
  • Member, National Wound Care Strategy Programme (NWCSP) - Research work stream committee
  • Member, Cochrane Wounds Clinical Prioritisation Team
Regional / Local:
  • Deputy Chair, NIHR Research for Patient Benefit (RfPB) West Midlands funding panel
  • Clinical Research Lead [CRL], Division 6 - NIHR Clinical Research Network (CRN) West Midlands
  • Clinical Research Specialty Lead [CRSL] for General Surgery - Clinical Research Network (CRN) West Midlands
  • Surgical lead, Clinical Academic Training Committee, Health Education England (West Midlands)
  • Senior advisor, West Midlands Research Collaborative

Publications

IMPACT SUMMARY (March 2025): Total number of citations: 13,397  h-index: 52  i10-index: 143

Selected publications

SUNRRISE Trial Study Group. Negative pressure dressings to prevent surgical site infection after emergency laparotomy: The SUNRRISE randomized clinical trial. JAMA 2025 Jan 27; doi: 10.1001/jama.2024.24764

ESCP EAGLE Safe Anastomosis Collaborative and NIHR Global Health Research Unit in Surgery. Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped- wedge, cluster-randomized trial in 64 countries. Br J Surg. 2024 Jan 3;111(1):znad370.

Choodari-Oskooei B, Blenkinsop A, Handley K, Pinkney T, Parmar MKB. Multi-arm multi-stage (MAMS) randomised selection designs: impact of treatment selection rules on the operating characteristics. BMC Med Res Methodol. 2024 Jun 3;24(1):124

NIHR Global Research Health Unit on Global Surgery. Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster-randomised trial in seven low- income and middle-income countries. Lancet. 2022 Nov 19;400(10365):1767-1776.

NIHR Global Health Unit on Global Surgery. Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries. Lancet. 2022 Nov 5;400(10363):1607-1617.

HART Collaborative. Incisional hernia following colorectal cancer surgery according to suture technique: Hughes Abdominal Repair Randomized Trial (HART). Br J Surg. 2022 Aug 8:znac198.

Newton K, Dumville J, Pearce L, Pinkney T, Hill J; PPAC2 Collaborators. Postoperative Packing of Perianal Abscess Cavities (PPAC2): randomized clinical trial. Br J Surg. 2022 Aug 5:znac225.

National Institute for Health Research Global Research Health Unit on Global Surgery. Delphi prioritization and development of global surgery guidelines for the prevention of surgical-site infection. Br J Surg. 2020 Mar 24. doi: 10.1002/bjs.11530.

Beard DJ, Campbell MK, Blazeby JM, Carr AJ, Weijer C, Cuthbertson BH, Pinkney T, et al. Considerations and methods for placebo controls in surgical trials (ASPIRE guidelines). Lancet. 2020 Mar 7;395(10226):828-838.  

Reinforcement of Closure of Stoma Site (ROCSS) Collaborative and West Midlands Research Collaborative (Co-chair; Executive Writing Group). Prophylactic biological mesh reinforcement versus standard closure of stoma site (ROCSS): a multicentre, randomised controlled trial. Lancet. 2020 Feb 8;395(10222):417-426. 

Pinkney TD, Calvert M, Bartlett DC, Gheorghe A, Redman V, Dowswell G, Hawkins W,  et al;  West Midlands Research Collaborative; ROSSINI Trial Investigators. Impact of wound edge protection devices on surgical site infection after laparotomy: multicentre randomised controlled trial (ROSSINI Trial). British Medical Journal 2013 Jul 31;347:f4305 

2017 European Society of Coloproctology (ESCP) collaborating group (Chair; Executive Writing Group).  An international multicentre prospective audit of elective rectal cancer surgery; operative approach versus outcome, including transanal total mesorectal excision (TaTME). Colorectal Dis. 2018 Sep;20 Suppl 6:33-46  

Pinkney TD, Morton DG. Novel approaches to surgical trials and the assessment of new surgical technologies. British Journal of Surgery 2015 Jan;102(2):e10-1. 

Bhangu A, Kolias AG, Pinkney T, Hall NJ, Fitzgerald JE. Surgical research collaboratives in the UK. Lancet 382 (9898), 1091-1092. 

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