Mr Samir Mehta

Mr Samir Mehta

Department of Applied Health Sciences
Senior Medical Statistician

Contact details

Address
Birmingham Clinical Trials Unit (BCTU)
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Samir Mehta has over 10 years’ experience in the design and analysis of clinical trials working as a Medical Statistician for the Birmingham Clinical Trials Unit (BCTU).

Samir's main portfolios within BCTU are trials related to Renal disease, surgical interventions and Atrial Fibrillation (AF).

Samir has also worked in trials related to Parkinson’s and cardiovascular disease, and is an experienced user of both major statistical analysis software packages SAS and STATA as required by MHRA for analysis of clinical trials.

Qualifications

  • MSc in Medical Statistics, University of Leicester, 2010
  • BSc (Hons) in Mathematics with Business Management, University Of Birmingham, 2009

Teaching

Other activities

  • Statistical reviewer for the National Institute for Health Research (HTA, EME, RfPB)
  • Independent statistician on Trial Steering and Data Monitoring Committees contributing to the oversight and direction of externally run clinical trials

Publications

Recent publications

Article

Spencer, S, Desborough, R, Mehta, S, Ives, N & Bhandari, S 2024, 'Cystatin C vs Creatinine eGFR in Advanced CKD: an analysis of the STOP-ACEi Trial ', Clinical Kidney Journal. https://doi.org/10.1093/ckj/sfae268

Sterliński, M, Bunting, K, Boriani, G, Boveda, S, Guasch, E, Mont, L, Rajappan, K, Sommer, P, Mehta, S, Sun, Y, Gale, CP, van Deutekom, C, van Gelder, IC & Kotecha, D 2024, 'Design and deployment of the STEEER-AF trial to evaluate and improve guideline adherence: A cluster-randomised trial by the European Society of Cardiology and European Heart Rhythm Association', EP Europace, vol. 26, no. 7, euae178. https://doi.org/10.1093/europace/euae178

Bhandari, S, Mehta, S, Khawaja, A, Cleland, JGF, Rowland, N & Cockwell, P 2024, 'Evaluation of the stopping angiotensin converting enzyme inhibitor compared to angiotensin receptor blocker (STOP ACEi trial) in advanced and progressive chronic kidney disease', Kidney International, vol. 105, no. 1, pp. 200-208. https://doi.org/10.1016/j.kint.2023.09.012

EXALT Trial Team 2024, 'Home-based EXercise and motivAtional programme before and after Liver Transplantation (EXALT): study protocol for phase II two-centre, randomised controlled trial', BMJ Open Gastroenterology, vol. 11, no. 1, e001410. https://doi.org/10.1136/bmjgast-2024-001410

Reinforcement of Closure of Stoma Site (ROCSS) Collaborative and West Midlands Research Collaborative & Benson, R 2024, 'Long-term cost-effectiveness of insertion of a biological mesh during stoma-site closure: 5–8-year follow-up of the ROCSS randomized controlled trial', British Journal of Surgery, vol. 111, no. 8, znae159. https://doi.org/10.1093/bjs/znae159

SUNRRISE Trial Study Group 2024, 'Negative Pressure Dressings to Prevent Surgical Site Infection After Emergency Laparotomy: The SUNRRISE Randomized Clinical Trial', JAMA.

Khan, N, Steeds, R, Kyte, D, Fabritz, L, Collis, P, Chua, WWL, Stubbs, C, Mehta, S, Sun, Y, Nulty, M, Kirkham, K & Cotton, JM 2024, 'Pilot study to evaluate the use of remote patient monitoring to guide the timing of valve intervention in patients with severe asymptomatic aortic stenosis (APRAISE-AS): study protocol for a randomised controlled trial delivered in two tertiary cardiac centres in the UK', BMJ open, vol. 14, no. 6, e086587. https://doi.org/10.1136/bmjopen-2024-086587

Smith, ME, Knappett, R, Vickers, D, White, D, Schramm, CJ, Mehta, S, Sun, Y, Watkins, B, Chadburn, M, Jarrett, H, James, K, Brettell, E, Roberts, TE, Bance, ML, Tysome, JR, INTEGRATE (the UK ENT Trainee Research Network) & Saniasiaya, J (ed.) 2024, 'Protocol for a multicentre randomised controlled trial of STeroid Administration Routes For Idiopathic Sudden sensorineural Hearing loss: The STARFISH trial', PLOS One, vol. 19, no. 2, e0290480. https://doi.org/10.1371/journal.pone.0290480

Lasserson, D, Gaddu, P, Mehta, S, Ignatowicz, A, Greenfield, S, Prince, C, Cummins, C, Robinson, G, Rodrigues, J, Noble, S, Jowett, S, Toshner, M, Newnham, M & Turner, A 2024, 'Stopping anticoagulation for isolated or incidental pulmonary embolism: the STOPAPE RCT protocol', Health Technology Assessment. https://doi.org/10.3310/HRCW7937

Lasserson, D, Gaddu, P, Mehta, S, Ignatowicz, A, Greenfield, S, Prince, C, Cummins, C, Robinson, G, Rodrigues, J, Noble, S, Jowett, S, Toshner, M, Newnham, M & Turner, A 2024, 'Stopping anticoagulation for isolated or incidental sub-segmental pulmonary embolism: the challenges and lessons from the STOP-APE RCT ', Health Technology Assessment.

ACTIVE Consortium, Schranz, P, Mandalia, V & O’brien, S 2023, 'A randomized trial of autologous chondrocyte implantation versus alternative forms of surgical cartilage management in patients with a failed primary treatment for chondral or osteochondral defects in the knee', American Journal of Sports Medicine, vol. 51, no. 2, pp. 367-378. https://doi.org/10.1177/03635465221141907

PREDNOS Collaborative Group, NIHR Medicines for Children Research Network Nephrology Clinical Studies Group, Afentou, N, Frew, E, Mehta, S, Rowland, N, Woolley, R, Brettell, E, Khan, A, Milford, D, Bockenhauer, D, Saleem , MA, Hall, AS, Koziell, A, Maxwell, H, Hegde , S, Finlay, ER, Gilbert, RD, Jones, C, McKeever, K, Cook, W, Webb, NJA & Christian, MT 2022, 'Economic evaluation of using daily prednisolone versus placebo at the time of an upper respiratory tract infection for the management of children with steroid-sensitive nephrotic syndrome: a model-based analysis', PharmacoEconomics, vol. 6, no. 4, pp. 605-617. https://doi.org/10.1007/s41669-022-00334-6

Abstract

Bhandari, S, Mehta, S, Ives, N & Cockwell, P 2024, 'WCN24-318: Utility of 2-year Kidney Failure Risk Equation for advanced chronic kidney disease: analysis from the STOP ACEi Trial', Kidney International Reports, vol. 9, no. 4, pp. S81-S82. https://doi.org/10.1016/j.ekir.2024.02.174

Spencer, S, Desborough, R, Mehta, S, Rowland, N & Bhandari, S 2024, 'WCN24-398: Report on STOP-ACEi trial: reviewing cystatin C levels in CKD patients', Kidney International Reports, vol. 9, no. 4, pp. S83-S83. https://doi.org/10.1016/j.ekir.2024.02.176

Letter

Bhandari, S, Mehta, S, Rowland, N & Cockwell, P 2023, 'Utility of 2-year kidney failure risk equation for advanced chronic kidney disease: analysis from the STOP-ACEi trial', Nephrology, Dialysis, Transplantation. https://doi.org/10.1093/ndt/gfad263

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