Dr Maria Makarova

Dr Maria Makarova

Institute of Metabolism and Systems Research
Assistant Professor

Dr Maria Makarova is a Group leader at the Institute of Metabolism and Systems Research at College of Medical and Dental Sciences. Her research is focussed on the chemical biology of lipid metabolism, linking genetics and membrane biophysics with applications in evolution, cell physiology, and industrial microbiology.

Qualifications

  • PhD in experimental oncology (Russian Cancer Research Centre), 2010
  • Diploma in Biochemistry (Lomonosov Moscow State University), 2006

Teaching

  • 2022 – present. Undergraduate Lecturing: 1st year Biosciences, LC Fundamentals in Biochemistry (topics: TCA cycle, Glycolysis, Regulation of Metabolism).
  • 2022 – present. Undergraduate Lecturing: 1st year Biosciences, LC Chemistry for Biochemists (topics: Organic Chemistry).
  • 2021 – present. Undergraduate Lecturing: 1st year Biosciences, LC Metabolism ((topics: Metabolism across sciences, Methods in metabolism research, Central carbon metabolism, TCA cycle, Glycolysis).
  • 2021 – present. Undergraduate Lecturing: 2nd year Biosciences, LI Membranes Energy and Metabolism (topics: Amino acid metabolism, Lipid metabolism, Carbohydrate metabolism).

Publications

Recent publications

Article

Panconi, L, Tansell, A, Collins, AJ, Makarova, M & Owen, DM 2024, 'Three-dimensional topology-based analysis segments volumetric and spatiotemporal fluorescence microscopy', Biological Imaging, vol. 4, e1. https://doi.org/10.1017/S2633903X23000260

Panconi, L, Lorenz, CD, May, RC, Owen, DM & Makarova, M 2023, 'Phospholipid tail asymmetry allows cellular adaptation to anoxic environments', The Journal of biological chemistry, vol. 299, no. 9, 105134. https://doi.org/10.1016/j.jbc.2023.105134

Grimes, J, Koszegi, Z, Lanoiselee, Y, Miljus, T, O'Brien, SL, Stepniewski, TM, Medel-Lacruz, B, Baidya, M, Makarova, M, Mistry, R, Goulding, J, Drube, J, Hoffmann, C, Owen, DM, Shukla, AK, Selent, J, Hill, SJ & Calebiro, D 2023, 'Plasma membrane preassociation drives β-arrestin coupling to receptors and activation', Cell, vol. 186, no. 10, pp. 2238-2255.e20. https://doi.org/10.1016/j.cell.2023.04.018

Saidykhan, L, Correia, J, Romanyuk, A, Desanti, GE, Taylor-Smith, L, Makarova, M, Ballou, ER & May, RC 2022, 'An in vitro method for inducing titan cells reveals novel features of yeast-to-titan switching in the human fungal pathogen Cryptococcus gattii', PLoS Pathogens, vol. 18, no. 8, e1010321. https://doi.org/10.1371/journal.ppat.1010321

Panconi, L, Makarova, M, Lambert, E, May, R & Owen, D 2022, 'Topology‐based fluorescence image analysis for automated cell identification and segmentation', Journal of Biophotonics. https://doi.org/10.1002/jbio.202200199

Simoncelli, S, Makarova, M, Wardley, W & Owen, DM 2017, 'Toward an axial nanoscale ruler for fluorescence microscopy', ACS Nano, vol. 11, no. 12, pp. 11762-11767. https://doi.org/10.1021/acsnano.7b07133

Chapter

Makarova, M & May, RC 2021, Fungal extracellular vesicles in interkingdom communication. in M Rodrigues & G Janbon (eds), Fungal Extracellular Vesicles: Biological Roles. 1 edn, Current Topics in Microbiology and Immunology, vol. 432, Springer, Cham, pp. 81-88. https://doi.org/10.1007/978-3-030-83391-6_8

Comment/debate

Saidykhan, L, Correia, J, Romanyuk, A, Peacock, AFA, Desanti, GE, Taylor-Smith, L, Makarova, M, Ballou, ER & May, RC 2022, 'Correction: An in vitro method for inducing titan cells reveals novel features of yeast-to-titan switching in the human fungal pathogen Cryptococcus gattii', PLoS Pathogens, vol. 18, no. 11, e1011001. https://doi.org/10.1371/journal.ppat.1011001

Preprint

Panconi, L, Lorenz, CD, May, R, Owen, D & Makarova, M 2022 'Phospholipid tail asymmetry allows cellular adaptation to anoxic environments' bioRxiv. https://doi.org/10.1101/2022.08.04.502790

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