Recent publications
Article
Griffiths, K, Mellado, MR, Chung, R, Lally, J, McQueen, G, Sendt, K-V, Gillespie, A, Ibrahim, M, Richter, A, Shields, A, Ponsford, M, Jolles, S, Hodsoll, J, Pollak, TA, Upthegrove, R, Egerton, A & Maccabe, JH 2024, 'Changes in immunoglobulin levels during clozapine treatment in schizophrenia', Brain, Behavior, and Immunity, vol. 115, pp. 223-228. https://doi.org/10.1016/j.bbi.2023.10.001
PANORAMIC Virology Group, Standing, JF, Buggiotti, L, Guerra-Assuncao, JA, Woodall, M, Ellis, S, Agyeman, AA, Miller, C, Okechukwu, M, Kirkpatrick, E, Jacobs, AI, Williams, CA, Roy, S, Martin-Bernal, LM, Williams, R, Smith, CM, Sanderson, T, Ashford, FB, Emmanuel, B, Afzal, ZM, Shields, A, Richter, AG, Dorward, J, Gbinigie, O, Van Hecke, O, Lown, M, Francis, N, Jani, B, Richards, DB, Rahman, NM, Yu, L-M, Thomas, NPB, Hart, ND, Evans, P, Andersson, M, Hayward, G, Hood, K, Nguyen-Van-Tam, JS, Little, P, Hobbs, FDR, Khoo, S, Butler, C, Lowe, DM & Breuer, J 2024, 'Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients', Nature Communications, vol. 15, no. 1, 1652. https://doi.org/10.1038/s41467-024-45641-0
Shields, AM, Faustini, SE, Young, S, Terjesen, S, McCarthy, NI, Anderson, RL, Drayson, MT & Richter, AG 2023, 'Clinical and laboratory characteristics of patients with symptomatic secondary immunodeficiency following the treatment of haematological malignancies', EJHaem, vol. 4, no. 2, pp. 339-349. https://doi.org/10.1002/jha2.683
Jones, R, Morales-Munoz, I, Shields, A, Blackman, G, Legge, SE, Pritchard, M, Kornblum, D, MacCabe, JH & Upthegrove, R 2023, 'Early neutrophil trajectory following clozapine may predict clozapine response - Results from an observational study using electronic health records', Brain, Behavior, and Immunity, vol. 113, pp. 267-274. https://doi.org/10.1016/j.bbi.2023.07.012
Ward, KE, Steadman, L, Karim, AR, Reynolds, GM, Pugh, M, Chua, W, Faustini, SE, Veenith, T, Thwaites, RS, Openshaw, PJM, Drayson, MT, Shields, AM, Cunningham, AF, Wraith, DC & Richter, AG 2023, 'SARS-CoV-2 infection is associated with anti-desmoglein 2 autoantibody detection', Clinical and Experimental Immunology, vol. 213, no. 2, pp. 243-251. https://doi.org/10.1093/cei/uxad046
Faustini, SE, Cook, A, Hill, H, Al-Taei, S, Heaney, J, Efstathiou, E, Tanner, C, Townsend, N, Ahmed, Z, Dinally, M, Hoque, M, Goodall, M, Stamataki, Z, Plant, T, Chapple, I, Cunningham, AF, Drayson, MT, Shields, AM & Richter, AG 2023, 'Saliva antiviral antibody levels are detectable but correlate poorly with serum antibody levels following SARS-CoV-2 infection and/or vaccination', Journal of Infection, vol. 87, no. 4, pp. 328-335. https://doi.org/10.1016/j.jinf.2023.07.018
Vivaldi, G, Jolliffe, DA, Faustini, S, Shields, AM, Holt, H, Perdek, N, Talaei, M, Tydeman, F, Chambers, ES, Cai, W, Li, W, Gibbons, JM, Pade, C, McKnight, Á, Shaheen, SO, Richter, AG & Martineau, AR 2022, 'Correlation Between Postvaccination Anti-Spike Antibody Titers and Protection Against Breakthrough Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Population-Based Longitudinal Study', The Journal of Infectious Diseases, vol. 226, no. 11, pp. 1903-1908. https://doi.org/10.1093/infdis/jiac321
Shields, AM, Tadros, S, Al-Hakim, A, Nell, JM, Lin, MMN, Chan, M, Goddard, S, Dempster, J, Dziadzio, M, Patel, SY, Elkalifa, S, Huissoon, A, Duncan, CJA, Herwadkar, A, Khan, S, Bethune, C, Elcombe, S, Thaventhiran, J, Klenerman, P, Lowe, DM, Savic, S, Burns, SO & Richter, AG 2022, 'Impact of vaccination on hospitalization and mortality from COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience', Frontiers in immunology, vol. 13, 984376. https://doi.org/10.3389/fimmu.2022.984376
COV-AD consortium 2022, 'Increased Seroprevalence and Improved Antibody Responses Following Third Primary SARS-CoV-2 Immunisation: An Update From the COV-AD Study', Frontiers in immunology, vol. 13, 912571. https://doi.org/10.3389/fimmu.2022.912571
Outcomes following SARS-CoV-2 infection in patients with primary and secondary immunodeficiency in the UK group 2022, 'Outcomes following SARS-CoV-2 infection in patients with primary and secondary immunodeficiency in the UK', Clinical and Experimental Immunology, vol. 209, no. 3, uxac008, pp. 247-258. https://doi.org/10.1093/cei/uxac008
COV-AD consortium 2022, 'SARS-CoV-2 Vaccine Responses in Individuals with Antibody Deficiency: Findings from the COV-AD Study', Journal of Clinical Immunology, vol. 42, no. 5, pp. 923-934. https://doi.org/10.1007/s10875-022-01231-7
Lamerton, R, Marcial-Juarez, E, Faustini, S, Perez-Toledo, M, Goodall, M, Jossi, S, Newby, ML, Chapple, I, Dietrich, T, Veenith, T, Shields, A, Harper, L, Henderson, I, Rayes, J, Wraith, D, Watson, S, Crispin, M, Drayson, M, Richter, A & Cunningham, A 2022, 'SARS-CoV-2 spike- and nucleoprotein-specific antibodies induced after vaccination or infection promote classical complement activation', Frontiers in immunology, vol. 13, 838780. https://doi.org/10.3389/fimmu.2022.838780
Shields, AM, Venkatachalam, S, Shafeek, S, Paneesha, S, Ford, M, Sheeran, T, Kelly, M, Qureshi, I, Salhan, B, Karim, F, De Silva, N, Stones, J, Lee, S, Khawaja, J, Kaudlay, PK, Whitmill, R, Kakepoto, GN, Parry, HM, Moss, P, Faustini, SE, Richter, AG, Drayson, MT & Basu, S 2022, 'SARS-CoV-2 vaccine responses following CD20-depletion treatment in patients with haematological and rheumatological disease: a West Midlands Research Consortium study', Clinical and Experimental Immunology, vol. 207, no. 1, pp. 3-10. https://doi.org/10.1093/cei/uxab018
Letter
Elhaj, MO, Richter, AG, Goddard, S & Shields, AM 2023, 'Dose reductions in immunoglobulin replacement are associated with increased antibiotic usage in patients with antibody deficiency', British Journal of Haematology, vol. 202, no. 4, pp. 900-903. https://doi.org/10.1111/bjh.18910
Faustini, S, Shields, A, Banham, G, Wall, N, Al-Taei, S, Tanner, C, Ahmed, Z, Efstathiou, E, Townsend, N, Goodall, M, Plant, T, Perez-Toledo, M, Jasiulewicz, A, Price, R, Mclaughlin, J, Farnan, J, Moore, J, Robertson, L, Nesbit, A, Curry, G, Black, A, Cunningham, A, Harper, L, Moore, T, Drayson, M & Richter, A 2022, 'Cross reactivity of spike glycoprotein induced antibody against Delta and Omicron variants before and after third SARS-CoV-2 vaccine dose in healthy and immunocompromised individuals', Journal of Infection, vol. 84, no. 4, pp. 579-613. https://doi.org/10.1016/j.jinf.2022.01.002