Dr Swaroop Chakraborty M. Tech., PhD, MRSC-CChem, MRSB-CSci

School of Geography, Earth and Environmental Sciences
Research Fellow

Contact details

Email: s.chakraborty@bham.ac.uk

Dr. Chakraborty is an interdisciplinary researcher with profound expertise in the synthesis and characterisation of nanomaterials, as well as in investigating their biochemical transformations and implications for toxicity and practical applications. His work is prominently positioned at the intersection of nanotechnology, chemistry and biology, focusing on unveiling the mechanisms behind nanomaterials and metal-organic framework transformations. Dr. Chakraborty's research endeavors are currently supported by two prestigious EU-funded projects: H2020-SABYDOMA and Horizon Europe-MOZART. These projects are central to advancing the domain of nanosafety research, aiming to mitigate the risks associated with nanomaterials while maximising their beneficial applications. Through his involvement in these initiatives, Dr. Chakraborty is deeply committed to developing a mechanistic understanding of nanomaterial interactions and evaluating their toxicity using state-of-the-art in-vitro cellular models. His work promises to contribute significantly to the field, offering innovative solutions and safer nanomaterials for diverse applications.

Qualifications

PhD in Bioengineering

M. Tech in Biotechnology

Teaching

Teaching Assistant of Inorganic Spectroscopy (Graphite Furnace AAS, ICP-OES/MS)

M.Res teaching at University of Birmingham on nanoparticles synthesis, characterization and stable isotope labelling.

Other activities

a) GEES Early Career Development Network Representative

b) Member of LES Research and Knowledge Transfer committee (R&KT)

c)Reviewer of Journals RSC Environmental Science: Nano, Elsevier Toxicology Reports, ACS Environmental Pollution, Frontiers in Toxicology.

Publications

Recent publications

Article

Patel, A, Chakraborty, S, Misra, SK & Datta, B 2024, 'Hydrolytic Enzyme-Facilitated Mass Spectrometric Investigation of Metals in Processed Food Matrices', ACS Food Science & Technology. https://doi.org/10.1021/acsfoodscitech.3c00695

Bhadane, P, Mahato, P, Menon, D, Satpathy, BK, Wu, L, Chakraborty, S, Goyal, P, Lynch, I & Misra, SK 2024, 'Hydrolytically stable nanosheets of Cu–imidazolate MOF for selective trapping and simultaneous removal of multiple heavy metal ions', Environmental Science: Nano. https://doi.org/10.1039/D3EN00754E

Ibrahim, B, Akere, TH, Chakraborty, S, Valsami-Jones, E & Ali-Boucetta, H 2024, 'Modulation of Heat Shock Protein Expression in Alveolar Adenocarcinoma Cells through Gold Nanoparticles and Cisplatin Treatment', Pharmaceutics, vol. 16, no. 3, 380. https://doi.org/10.3390/pharmaceutics16030380

Malvi, B, Chakraborty, S, Chaudhari, R, Kumar, A, Balasubramanian, C & Misra, SK 2023, 'Development of isotopically labelled ⁶⁵Cu embedded PMMA-⁶⁵CuO nanocomposites for detection and quantification of PMMA bone cement degradation at trace levels', Materials Today Communications, vol. 36, 106849. https://doi.org/10.1016/j.mtcomm.2023.106849

Chakraborty, S, Menon, D, Akhil Varri, VS, Sahoo, M, Ranganathan, R, Zhang, P & Misra, SK 2023, 'Does the doping strategy of ferrite nanoparticles create a correlation between reactivity and toxicity?', Environmental Science: Nano, vol. 2023, no. 10, pp. 1554-1569. https://doi.org/10.1039/d3en00076a

Ibrahim, B, Akere, TH, Chakraborty, S, Valsami-Jones, E & Ali-Boucetta, H 2023, 'Functionalized Gold Nanoparticles Suppress the Proliferation of Human Lung Alveolar Adenocarcinoma Cells by Deubiquitinating Enzymes Inhibition', ACS Omega, vol. 8, no. 43, pp. 40622-40638. https://doi.org/10.1021/acsomega.3c05452

Ibrahim, B, Akere, TH, Chakraborty, S, Valsami-Jones, E & Ali-Boucetta, H 2023, 'Gold Nanoparticles Induced Size Dependent Cytotoxicity on Human Alveolar Adenocarcinoma Cells by Inhibiting the Ubiquitin Proteasome System', Pharmaceutics, vol. 15, no. 2, 432. https://doi.org/10.3390/pharmaceutics15020432

Chakraborty, S, Prakash, P, Shah, J, Mayya, C, Singh, S, Ranganathan, R, Soppina, V, Jones, EV & Misra, SK 2022, 'CuO nanoparticles as copper-ion reservoirs for Elesclomol-mediated intracellular oxidative stress: implications for anticancer therapies', ACS Applied Nano Materials, vol. 5, no. 1, pp. 1607-1620. https://doi.org/10.1021/acsanm.1c04350

Chakraborty, S, Prasad, R, Pandey, PK, Khan, A, Jain, NK, Jones, EV, Srivastava, R & Misra, SK 2022, 'Doxorubicin encapsulated hollow self-assembled CuS nanoparticles clusters for bio-responsive chemo-photo therapy', Materials Letters, vol. 327, 133017. https://doi.org/10.1016/j.matlet.2022.133017

Butreddy, P, Chakraborty, S, Soppina, P, Behera, R, Soppina, V & Misra, SK 2022, 'Novel dual labelled nanoprobes for nanosafety studies: quantification and imaging experiment of CuO nanoparticles in C. elegans', Chemosphere, vol. 286, 131698. https://doi.org/10.1016/j.chemosphere.2021.131698

Goyal, P, Soppina, P, Misra, SK, Valsami-Jones, E, Soppina, V & Chakraborty, S 2022, 'Toxicological Impact and in Vivo Tracing of Rhodamine Functionalised ZIF-8 Nanoparticles', Frontiers in toxicology, vol. 4, 917749. https://doi.org/10.3389/ftox.2022.917749

Guo, Z, Zhang, P, Chakraborty, S, Chetwynd, AJ, Monikh, FA, Stark, C, Ali-Boucetta, H, Wilson, S, Lynch, I & Valsami-Jones, E 2021, 'Biotransformation modulates the penetration of metallic nanomaterials across an artificial blood–brain barrier model', Proceedings of the National Academy of Sciences, vol. 118, no. 28, e2105245118. https://doi.org/10.1073/pnas.2105245118

Chapter (peer-reviewed)

Chakraborty, S & Misra, S 2022, Tailoring of intrinsic physicochemical properties of nanoparticles for antimicrobial therapy. in R Rajendran, HJ Maria, S Thomas & N Kalarikkal (eds), Handbook of Research on Nano-Drug Delivery and Tissue Engineering: Guide to Strengthening Healthcare Systems. 1st edn, Apple Academic Press, pp. 209-252. https://doi.org/10.1201/9781003161196-9

Chapter

Menon, D, Chakraborty, S, Goyal, P, Valsami-Jones, E & Misra, SK 2023, Nano Metal-Organic Frameworks as a Promising Candidate for Biomedical Applications. in R Srivastava, SK Debnath & R Prasad (eds), Nanomaterials in Healthcare. 1st edn, Routledge, pp. 115-132. https://doi.org/10.1201/9781003322368-7

Review article

Menon, D & Chakraborty, S 2023, 'How safe are nanoscale metal-organic frameworks?', Frontiers in toxicology, vol. 5, 1233854. https://doi.org/10.3389/ftox.2023.1233854

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