Recent publications
Article
Dashti, Y, Mohammadipanah, F, Zhang, Y, Cerqueira Diaz, PM, Vocat, A, Zabala, D, Fage, CD, Romero-Canelon, I, Bunk, B, Spröer, C, Alkhalaf, LM, Overmann, J, Cole, ST & Challis, GL 2024, 'Discovery and Biosynthesis of Persiathiacins: Unusual Polyglycosylated Thiopeptides Active Against Multidrug Resistant Tuberculosis', ACS Infectious Diseases, vol. 10, no. 9, pp. 3378-3391. https://doi.org/10.1021/acsinfecdis.4c00502
Fry, ME, Alsaif, S, Khanom, Y, Keirle, AK, Pheasey, CE, Song, JI, Bedford, RA, Romero Canelon, I, Sadler, PJ & Coverdale, J 2024, 'Ir(III) Diamine Transfer Hydrogenation Catalysts in Cancer Cells', ChemCatChem. https://doi.org/10.1002/cctc.202401490
Tabrizi, L, Jones, AM, Romero-Canelon, I & Erxleben, A 2024, 'Multiaction Pt(IV) Complexes: Cytotoxicity in Ovarian Cancer Cell Lines and Mechanistic Studies', Inorganic Chemistry, vol. 63, no. 32, pp. 14958-14968. https://doi.org/10.1021/acs.inorgchem.4c01586
Bridgewater, HE, Bolitho, EM, Romero-Canelón, I, Sadler, PJ & Coverdale, JPC 2023, 'Targeting cancer lactate metabolism with synergistic combinations of synthetic catalysts and monocarboxylate transporter inhibitors', Journal of Biological Inorganic Chemistry, vol. 28, no. 3, pp. 345-353. https://doi.org/10.1007/s00775-023-01994-3
Rana, M, Perotti, A, Bisset, LM, Smith, JD, Lamden, E, Khan, Z, Ismail, MK, Ellis, K, Armstrong, KA, Hodder, SL, Bertoli, C, Meneguello, L, de Bruin, RAM, Morris, JR, Romero-Canelon, I, Tucker, JHR & Hodges, NJ 2022, 'A ferrocene-containing nucleoside analogue targets DNA replication in pancreatic cancer cells', Metallomics, vol. 14, no. 7, mfac041. https://doi.org/10.1093/mtomcs/mfac041
Kladnik, J, Coverdale, JPC, Kljun, J, Burmeister, H, Lippman, P, Ellis, FG, Jones, AM, Ott, I, Romero-Canelón, I & Turel, I 2021, 'Organoruthenium complexes with benzo-fused pyrithiones overcome platinum resistance in ovarian cancer cells', Cancers, vol. 13, no. 10, 2493. https://doi.org/10.3390/cancers13102493
Lam, YPY, Wootton, CA, Hands-Portman, I, Wei, J, Chiu, CKC, Romero-Canelon, I, Lermyte, F, Barrow, MP & O’Connor, PB 2020, 'Determination of the aggregate binding site of amyloid protofibrils using electron capture dissociation tandem mass spectrometry', Journal of the American Society for Mass Spectrometry, vol. 31, no. 2, pp. 267-276. https://doi.org/10.1021/jasms.9b00053
Oliveira, CG, Romero-Canelón, I, Coverdale, JPC, Maia, PIS, Clarkson, GJ, Deflon, VM & Sadler, PJ 2020, 'Novel tetranuclear PdII and PtII anticancer complexes derived from pyrene thiosemicarbazones', Dalton Transactions, no. 28, pp. 9595-9604. https://doi.org/10.1039/D0DT01133A
Ballesta, A, Billy, F, Coverdale, JPC, Song, J-I, Sanchez-Cano, C, Romero-Canelón, I & Sadler, PJ 2019, 'Kinetic analysis of the accumulation of a half-sandwich organo-osmium pro-drug in cancer cells', Metallomics, vol. 11, no. 10, pp. 1648-1656. https://doi.org/10.1039/c9mt00173e
Sanchez-Cano, C, Gianolio, D, Romero-Canelón, I, Tucoulou, R & Sadler, PJ 2019, 'Nanofocused synchrotron x-ray absorption studies of the intracellular redox state of an organometallic complex in cancer cells', Chemical Communications , vol. 55, no. 49, pp. 7065-7068. https://doi.org/10.1039/C9CC01675A
Oliveira, CG, Romero-Canelón, I, Silva, MM, Coverdale, JPC, Maia, PIS, Batista, AA, Castelli, S, Desideri, A, Sadler, PJ & Deflon, VM 2019, 'Palladium (II) complexes with thiosemicarbazones derived from pyrene as topoisomerase IB inhibitors', Dalton Transactions, vol. 48, no. 44, pp. 16509-16517. https://doi.org/10.1039/C9DT02570G
Shi, H, Wang, Q, Venkatesh, V, Feng, G, Young, LS, Romero-Canelón, I, Zeng, M & Sadler, PJ 2019, 'Photoactive platinum(IV) complex conjugated to a cancer-cell-targeting cyclic peptide', Dalton Transactions, vol. 48, no. 24, pp. 8560-8564. https://doi.org/10.1039/C9DT00909D
Finnegan, ME, Visanji, N, Romero-canelon, I, House, E, Rajan, S, Mosselmans, JFW, Hazrati, L, Dobson, J & Collingwood, JF 2019, 'Synchrotron XRF imaging of Alzheimer’s disease basal ganglia reveals linear dependence of high-field magnetic resonance microscopy on tissue iron concentration', Journal of Neuroscience Methods, vol. 319, pp. 28-39. https://doi.org/10.1016/j.jneumeth.2019.03.002
Review article
Chopra, V, Sangarappillai, R, Romero-Canelón, I & Jones, AM 2020, 'Lysyl oxidase like-2 (LOXL2): an emerging oncology target', Advanced Therapeutics, vol. 3, no. 2, 1900119. https://doi.org/10.1002/adtp.201900119
Coverdale, J, Laroiya-McCarron, T & Romero-Canelón, I 2019, 'Designing ruthenium anticancer drugs: what have we learnt from the key drug candidates?', Inorganics, vol. 7, no. 3, 31. https://doi.org/10.3390/inorganics7030031
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