Recent publications
Article
James, N, Pirrie, S, Liu, W, Catto, J, Jefferson, K, Patel, P, Hughes, A, Pope, A, Nanton, V, Mintz, HP, Knight, A, Gallagher, J & Bryan, RT 2024, 'Image directed redesign of bladder cancer treatment pathways: the BladderPath RCT', Health Technology Assessment, vol. 28, no. 42, pp. 1-65. https://doi.org/10.3310/DEHT5407
Birtle, A, Jones, R, Chester, J, Lewis, R, Biscombe, K, Johnson, M, Blacker, A, Bryan, R, Catto, JWF, Choudhury, A, Das, P, Jagdev, S, Powles, T, Wagstaff, J, Chung, KC, Cafferty, F & Hall, EC 2024, 'Improved Disease Free Survival With Adjuvant Chemotherapy After Nephroureterectomy for Upper Tract Urothelial Cancer: Final Results of the POUT Trial', Journal of Clinical Oncology . https://doi.org/10.1200/JCO.23.01659
Sankin, A, Dave, P, Cherrill, L-R, Boucher, RH, Zeegers, MP, Cheng, KK, James, ND, Agalliu, I & Bryan, RT 2024, 'Low-grade urothelial carcinoma recurs at a tempo that naturally accelerates over time', Urology. https://doi.org/10.1016/j.urology.2024.07.017
Kerzeli, IK, Kostakis, A, Türker, P, Malmström, P-U, Hemdan, T, Mezheyeuski, A, Ward, DG, Bryan, RT, Segersten, U, Lord, M & Mangsbo, SM 2023, 'Elevated levels of MMP12 sourced from macrophages are associated with poor prognosis in urothelial bladder cancer', BMC Cancer, vol. 23, no. 1, 605. https://doi.org/10.1186/s12885-023-11100-0
The BladderPath trial management group 2023, 'Properties of non-coding mutation hotspots as urinary biomarkers for bladder cancer detection', Scientific Reports, vol. 13, no. 1, 1060. https://doi.org/10.1038/s41598-023-27675-4
SELENIB Investigators, Bryan, R, Pirrie, S, Abbotts, B, Maycock, S, During, V, Lewis, C, Grant, M, Bird, D, Devall, A, Wallace, DM, James, N, Billingham, L, Zeegers, M & Cheng, KK 2023, 'Selenium and Vitamin E for Prevention of Non–Muscle-Invasive Bladder Cancer Recurrence and Progression: A Randomized Clinical Trial', JAMA network open, vol. 6, no. 10, e2337494. https://doi.org/10.1001/jamanetworkopen.2023.37494
Goel, A, Ward, DG, Noyvert, B, Yu, M, Gordon, NS, Abbotts, B, Colbourne, JK, Kissane, S, James, ND, Zeegers, MP, Cheng, KK, Cazier, J, Whalley, CM, Beggs, AD, Palles, C, Arnold, R & Bryan, RT 2022, 'Combined exome and transcriptome sequencing of non-muscle-invasive bladder cancer: associations between genomic changes, expression subtypes, and clinical outcomes', Genome medicine, vol. 14, no. 1, 59 . https://doi.org/10.1186/s13073-022-01056-4
Richters, A, Kiemeney, LALM, Mehra, N, Westgeest, HM, Birtle, A, Bryan, RT & Aben, KKH 2022, 'Evidence or prejudice? Critical re-analysis of randomized controlled trials comparing overall survival after cisplatin versus carboplatin-based regimens in advanced urothelial carcinoma', Clinical Genitourinary Cancer, vol. 20, no. 4, pp. e346-e352. https://doi.org/10.1016/j.clgc.2021.12.017
Galesloot, TE, Grotenhuis, AJ, Kolev, D, Aben, KK, Bryan, RT, Catto, JWF, Cheng, KK, Conroy, S, Dyrskjøt, L, Fleshner, NE, James, ND, Lamy, P, Lindskrog, SV, Malats, N, Mengual, L, Verhaegh, G, Zeegers, MP, Kiemeney, LALM & Vermeulen, SH 2022, 'Genome-wide meta-analysis identifies novel genes associated with recurrence and progression in non-muscle-invasive bladder cancer', European Urology Oncology, vol. 5, no. 1, pp. 70-83. https://doi.org/10.1016/j.euo.2021.07.001
BladderPath Trial Management Group 2022, 'Highly sensitive and specific detection of bladder cancer via targeted ultra-deep sequencing of urinary DNA', European Urology Oncology. https://doi.org/10.1016/j.euo.2022.03.005
Editorial
Mintz, HP, Dosanjh, ARS, Parsons, H, Sydes, M, Bryan, RT, James, ND & Patel, P 2023, 'Making administrative healthcare systems clinical data the future of clinical trials: lessons from BladderPath', BMJ Oncology, vol. 2, no. 1, e000038. https://doi.org/10.1136/bmjonc-2023-000038
Review article
Nanton, V, Bryan, R, Pope, A, Hughes, A, Jefferson, K, Catto, J, Knight, A, Gallagher, J, Mintz, H, Pirrie, S, Liu, W, Young, A, Patel, P & James, N 2023, 'Boosting and broadening recruitment to UK cancer trials: towards a blueprint for action', BMJ Oncology, vol. 2, no. 1, e000092. https://doi.org/10.1136/bmjonc-2023-000092
Toren, P, Wilkins, A, Patel, K, Burley, A, Gris, T, Kockelbergh, R, Lodhi, T, Choudhury, A & Bryan, RT 2023, 'The sex gap in bladder cancer survival: a missing link in bladder cancer care?', Nature reviews. Urology. https://doi.org/10.1038/s41585-023-00806-2
Unsworth-White, S, Kitchen, M & Bryan, R 2022, 'Immunotherapy for non-muscle invasive bladder cancer: from the origins of BCG to novel therapies', Future Oncology, vol. 18, no. 1, pp. 105-115. https://doi.org/10.2217/fon-2021-0781
Ward, K, Kitchen, M, Mathias, S-J, Khanim, F & Bryan, R 2022, 'Novel intravesical therapeutics in the treatment of non-muscle invasive bladder cancer: horizon scanning', Frontiers in Surgery, vol. 9, 912438. https://doi.org/10.3389/fsurg.2022.912438
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