Bacterial Gene Regulation

The ability of bacteria to survive in a variety of environments depends on their ability to regulate gene expression in response to various environmental signals. In this module, students will learn about the molecular mechanisms of bacterial gene expression and its regulation, and their consequences for metabolism, transposition, differentiation and interactions with phage.

This module introduces you to aspects such as (i) the different levels of regulation during gene expression in bacteria and the mechanisms whereby control is exerted (ii) current methods for studying gene expression and regulation. It also provides opportunities for students to prepare work based on original scientific literature. Student's problem solving ability is developed through data handling classes.

By the end of the module you should be able to:

• Understand the different levels of gene control in bacteria, including the circuits that allow differentiation and multicellular behaviour;
• Be conversant with the current methodology for studying gene expression and control;
• Be able to work in groups and alone to solve problems relating to gene expression and regulation;
• Be able to analyse and explain orally current work based on the primary scientific literature. 

Assessment

Class Test : Class Test (50%)
Examination : Exam (Centrally timetabled) - Computer based (50%)