Christopher Green works as both a practicing physician in the NHS and an academic researcher with the University.
His NHS work takes him to the front line of acute care and speciality medicine work that focusses on the diagnosis and management of complex infection. During his clinical training in Infectious Diseases he was fortunate enough to be seconded to the University of Oxford to further develop his interests in vaccinology and global health. There he worked on the accelerated evaluation of novel vaccine candidates for enteric fever using a controlled human challenge model of infection and lead several phase 1 (first-in-human) clinical trials of new vaccine technologies against other infectious diseases.
The focus of his DPhil was in leading the world’s first clinical trials of viral-vectored vaccine technology for respiratory syncytial virus (RSV). This work was directedly relevant for the urgent research needed to develop new drugs and vaccines to safely control the COVID-19 pandemic a few years later.
He worked as the principal investigator for a large portfolio of urgent public health research at the same time as his clinical role in this period, which included membership of the SAGE group of scientists and work on hospital disease epidemiology and modelling.
His ongoing research interests include the development of new and novel vaccines through early-stage human trials, understanding the host immune response to infection/vaccination, and in preparing low- to middle-income countries (LMICs) to have the ‘next generation’ vaccine cold-chain systems needed to deploy new vaccine technologies and to mitigate the complex effects from climate change.