Dr Michael Sagmeister MRCP

Dr Michael Sagmeister

Institute of Metabolism and Systems Research
Honorary Clinical Research Fellow

Contact details

Email
m.sagmeister@bham.ac.uk
Address
Institute of Metabolism and Systems Research
University of Birmingham
Edgbaston
Birmingham
B15 2TT
UK

Michael Sagmeister is an Honorary Clinical Research Fellow undertaking a PhD at the Institute of Metabolism and Systems Research.

He has been awarded an MRC Clinical Research Training Fellowship to investigate causes and potential new treatments for muscle wasting in chronic kidney disease. His research project focuses on the role of cortisol metabolism in skeletal muscle tissue by the enzyme 11-beta hydroxysteroid dehydrogenase type 1 and uses pre-clinical models of kidney disease.

Michael studied medicine at University of Cambridge and University College London. He received his primary medical qualification in 2012. He has worked as a junior doctor in London and Munich, Germany, before moving to Birmingham in 2015 and training as an NIHR Academic Clinical Fellow in Nephrology. His previous research has explored complications affecting patients with ANCA-associated vasculitis or chronic kidney disease.

Qualifications

  • Specialty Certificate Examination in Nephrology, 2020
  • Membership of the Royal College of Physicians, 2014
  • Postgraduate Certificate in Clinical Education, King’s College London, 2014
  • M.B.B.S., University College London, 2012
  • BA(Hons) Preclinical Medical Studies with Intercalation in Pharmacology, University of Cambridge, 2009 

Other activities

Honorary Specialist Registrar in Renal Medicine, University Hospitals Birmingham NHS Foundation Trust

Publications

Sagmeister MS, Taylor AE, Fenton A, Wall NA, Chanouzas D, Nightingale PG, Ferro CJ, Arlt W, Cockwell P, Hardy RS, Harper L. Glucocorticoid activation by 11β-hydroxysteroid dehydrogenase enzymes in relation to inflammation and glycaemic control in chronic kidney disease: A cross-sectional study. Clin Endocrinol (Oxf). 2019;90(1):241-9. https://doi.org/10.1111/cen.13889

Sagmeister MS, Grigorescu M, Schönermarck U. Kidney transplantation in ANCA-associated vasculitis. J Nephrol. 2019;32(6):919-26. https://doi.org/10.1007/s40620-019-00642-x 

Chanouzas D, Sagmeister M, Faustini S, Nightingale P, Richter A, Ferro CJ, Morgan MD, Moss P, Harper L. Subclinical Reactivation of Cytomegalovirus Drives CD4+CD28null T-Cell Expansion and Impaired Immune Response to Pneumococcal Vaccination in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis. J Infect Dis. 2019;219(2):234-44. https://doi.org/10.1093/infdis/jiy493

Chanouzas D, Sagmeister M, Dyall L, Sharp P, Powley L, Johal S, Bowen J, Nightingale P, Ferro CJ, Morgan MD, Moss P, Harper L. The host cellular immune response to cytomegalovirus targets the endothelium and is associated with increased arterial stiffness in ANCA-associated vasculitis. Arthritis Res Ther. 2018;20(1):194. https://doi.org/10.1186/s13075-018-1695-8

Sagmeister MS, Weiss M, Eichhorn P, Habicht A, Habersetzer R, Fischereder M, Schönermarck U. Case report: de novo ANCA-associated vasculitis after kidney transplantation treated with rituximab and plasma exchange. BMC Nephrology. 2018;19(1):270. https://doi.org/10.1186/s12882-018-1086-z

Sagmeister MS and Harper L. Systemic Vasculitis. Book chapter in Barratt J, Harris K, Topham P (eds.). Oxford Desk Reference: Nephrology. Second edition. Oxford University Press. [in print]