Recent publications
Article
Mahida, RY, Yuan, Z, Kolluri, KK, Scott, A, Parekh, D, Hardy, RS, Matthay, MA, Perkins, GD, Janes, SM & Thickett, DR 2024, '11β hydroxysteroid dehydrogenase type 1 transgenic mesenchymal stem cells attenuate inflammation in models of sepsis', Frontiers in Bioengineering and Biotechnology, vol. 12, 1422761. https://doi.org/10.3389/fbioe.2024.1422761
Jasper, A, Faniyi, A, Davis, L, Grudzinska, F, Halston, R, Hazeldine, J, Parekh, D, Sapey, E, Thickett, D & Scott, A 2024, 'E-cigarette vapor renders neutrophils dysfunctional due to filamentous actin accumulation', Journal of Investigational Allergology and Clinical Immunology, vol. 153, no. 1, pp. 320-329.e8. https://doi.org/10.1016/j.jaci.2023.08.025
Quarton, S, Livesey, A, Jeff, C, Hatton, C, Scott, A, Parekh, D, Thickett, D, McNally, A & Sapey, E 2024, 'Metagenomics in the Diagnosis of Pneumonia: Protocol for a Systematic Review', JMIR Research Protocols, vol. 13, e57334. https://doi.org/10.2196/57334
Patel, A, Caruana, EJ, Hodson, J, Morrison, R, Khor, B, Gysling, S, Trevis, J, Mangel, T, Benson, R, Zakeri, R, Manders, J, Vaja, R, Rogers, L, Baker, P, Pournaras, DJ, Thickett, D, Hewison, M, Naidu, B & Lim, E 2024, 'Role of vitamin D supplementation in modifying outcomes after surgery: a systematic review of randomised controlled trials', BMJ open, vol. 14, no. 1, e073431. https://doi.org/10.1136/bmjopen-2023-073431
Quarton, S, McGee, K, Cumley, N, Behruznia, M, Jeff, C, Belchamber, K, Cox, M, Thickett, D, Scott, A, Parekh, D, McNally, A & Sapey, E 2024, 'Towards personalised anti-microbial and immune approaches to infections in acute care. Can real-time genomic-informed diagnosis of pathogens, and immune-focused therapies improve outcomes for patients? An observational, experimental study protocol', PLoS ONE, vol. 19, no. 3, e0298425. https://doi.org/10.1371/journal.pone.0298425
Mahida, RY, Lax, S, Bassford, CR, Scott, A, Parekh, D, Hardy, RS, Naidu, B, Matthay, MA, Stewart, PM, Cooper, MC, Perkins, GD & Thickett, DR 2023, 'Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS', Frontiers in immunology, vol. 14, 1159831. https://doi.org/10.3389/fimmu.2023.1159831
Grudzinska, FS, Faniyi, AA, Scott, A, Sapey, E & Thickett, DR 2023, 'Observational cohort study protocol: neutrophil function and energetics in adults with pneumonia and sepsis: Pneumonia Metabolism in Ageing (PUMA)', BMJ Open Respiratory Research, vol. 10, no. 1, e001806. https://doi.org/10.1136/bmjresp-2023-001806
Thein, OS, Ali, NA, Mahida, RY, Dancer, RCA, Ostermann, M, Amrein, K, Martucci, G, Scott, A, Thickett, DR & Parekh, D 2023, 'Raised FGF23 Correlates to Increased Mortality in Critical Illness, Independent of Vitamin D', Biology, vol. 12, no. 2, 309. https://doi.org/10.3390/biology12020309
Grudzinska, F, Jasper, A, Sapey, E, Thickett, D, Mauro, C, Scott, A & Barlow, J 2023, 'Real-time assessment of neutrophil metabolism and oxidative burst using extracellular flux analysis', Frontiers in immunology, vol. 14, 1083072. https://doi.org/10.3389/fimmu.2023.1083072
PHOSP-COVID study collaborative group 2023, 'Residual Lung Abnormalities after COVID-19 Hospitalization Interim Analysis of the UKILD Post-COVID-19 Study', American Journal of Respiratory and Critical Care Medicine, vol. 207, no. 6, pp. 693-703. https://doi.org/10.1164/rccm.202203-0564OC
Ahmad, S, Wrennall, JA, Goriounova, AS, Sekhri, M, Iskarpatyoti, JA, Ghosh, A, Abdelwahab, SH, Voeller, A, Rai, M, Mahida, RY, Krajewski, K, Ignar, DM, Greenbaum, A, Moran, TP, Tilley, SL, Thickett, DR, Sassano, MF & Tarran, R 2023, 'Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an ARDS Model', American Journal of Respiratory and Critical Care Medicine. https://doi.org/10.1164/rccm.202308-1393OC
Mahida, RY, Price, J, Lugg, ST, Li, H, Parekh, D, Scott, A, Harrison, P, Matthay, MA & Thickett, DR 2022, 'CD14-positive extracellular vesicles in bronchoalveolar lavage fluid as a new biomarker of acute respiratory distress syndrome', American journal of physiology. Lung cellular and molecular physiology, vol. 322, no. 4, pp. L617-L624. https://doi.org/10.1152/ajplung.00052.2022
Abstract
Roberts, SA, Lugg, ST, Faniyi, AA, Faustini, SE, Faniyi, C, Duffy, J, Hewison, M, Shields, A, Richter, AG, Parekh, D, Scott, A & Thickett, DR 2023, 'P165 Association between vitamin D deficiency and extended duration of COVID-19 symptoms', Thorax, vol. 77, no. Suppl 1, pp. A170-A171. https://doi.org/10.1136/thorax-2022-BTSabstracts.299
Letter
PHOSP-COVID Collaborative Group, ISARIC investigators, Jackson, T, Broome, M, McArdle, P, Moss, P, Thickett, D, Upthegrove, R, Wraith, D, Aldera, EL, Green, C & McGee, K 2024, 'Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease', Nature Immunology, vol. 25, no. 4, pp. 607-621. https://doi.org/10.1038/s41590-024-01778-0
Student Audit and Research in Surgery (STARSurg) Collaborative & European Surgical (EuroSurg) Collaborative 2022, 'CArdiovaSCulAr outcomes after major abDominal surgEry: study protocol for a multicentre, observational, prospective, international audit of postoperative cardiac complications after major abdominal surgery', British Journal of Anaesthesia, vol. 128, no. 5, pp. e324-e327. https://doi.org/10.1016/j.bja.2022.02.012
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