Recent publications
Article
Martin, CS, Crastin, A, Sagmeister, MS, Kalirai, MS, Turner, JD, MacDonald, L, Kurowska-Stolarska, M, Scheel-Toellner, D, Taylor, AE, Gilligan, LC, Storbeck, K, Price, M, Gorvin, CM, Filer, A, Mahida, R, Clark, AR, Jones, SW, Raza, K, Hewison, M & Hardy, RS 2024, 'Inflammation Dynamically Regulates Steroid Hormone Metabolism and Action within Macrophages in Rheumatoid Arthritis ', Journal of Autoimmunity, vol. 147, 103263. https://doi.org/10.1016/j.jaut.2024.103263
O’Neil, JD, Bolimowska, OO, Clayton, SA, Tang, T, Daley, KK, Lara-Reyna, S, Warner, J, Martin, CS, Mahida, RY, Hardy, RS, Arthur, JSC & Clark, AR 2023, 'Dexamethasone impairs the expression of antimicrobial mediators in lipopolysaccharide-activated primary macrophages by inhibiting both expression and function of interferon β', Frontiers in immunology, vol. 14, 1190261. https://doi.org/10.3389/fimmu.2023.1190261
Pucino, V, Nefla, M, Gauthier, V, Alsaleh, G, Clayton, SA, Marshall, J, Filer, A, Clark, AR, Raza, K & Buckley, CD 2023, 'Differential effect of lactate on synovial fibroblast and macrophage effector functions', Frontiers in immunology, vol. 14, 1183825. https://doi.org/10.3389/fimmu.2023.1183825
Clayton, SA, Lockwood, C, O’neil, JD, Daley, KK, Hain, S, Abdelmottaleb, D, Bolimowska, OO, Tennant, DA & Clark, AR 2023, 'The glucocorticoid dexamethasone inhibits HIF-1α stabilization and metabolic reprogramming in lipopolysaccharide-stimulated primary macrophages', Discovery Immunology, vol. 2, no. 1, kyad027, pp. 1-13. https://doi.org/10.1093/discim/kyad027
Clayton, SA, Daley, KK, Macdonald, L, Fernandez-vizarra, E, Bottegoni, G, O’Neil, JD, Major, T, Griffin, D, Zhuang, Q, Adewoye, AB, Woolcock, K, Jones, SW, Goodyear, C, Elmesmari, A, Filer, A, Tennant, DA, Alivernini, S, Buckley, CD, Pitceathly, RDS, Kurowska-stolarska, M & Clark, AR 2021, 'Inflammation causes remodeling of mitochondrial cytochrome c oxidase mediated by the bifunctional gene C15orf48', Science Advances, vol. 7, no. 50, eabl5182. https://doi.org/10.1126/sciadv.abl5182
Falconer, J, Pucino, V, Clayton, S, Marshall, J, Raizada, S, Adams, H, Philp, A, Clark, AR, Filer, A, Raza, K, Young, S & Buckley, C 2021, 'Spontaneously resolving joint inflammation is characterised by metabolic agility of fibroblast-like synoviocytes', Frontiers in immunology, vol. 12, 725641. https://doi.org/10.3389/fimmu.2021.725641
Alivernini, S, MacDonald, L, Elmesmari, A, Finlay, S, Tolusso, B, Gigante, MR, Petricca, L, Di Mario, C, Bui, L, Perniola, S, Attar, M, Gessi, M, Fedele, AL, Chilaka, S, Somma, D, Sansom, SN, Filer, A, McSharry, C, Millar, NL, Kirschner, K, Nerviani, A, Lewis, MJ, Pitzalis, C, Clark, AR, Ferraccioli, G, Udalova, I, Buckley, C, Gremese, E, McInnes, IB, Otto, TD & Kurowska-Stolarska, M 2020, 'Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis', Nature Medicine, vol. 26, no. 8, pp. 1295-1306. https://doi.org/10.1038/s41591-020-0939-8
Clark, A 2019, 'Enhancing tristetraprolin activity reduces the severity of cigarette smoke-induced experimental chronic obstructive pulmonary disease.', Clinical and Translational Immunology. https://doi.org/10.1002/cti2.1084
Clark, AR & Ohlmeyer, M 2019, 'Protein phosphatase 2A as a therapeutic target in inflammation and neurodegeneration', Pharmacology & Therapeutics, vol. 201, pp. 181-201. https://doi.org/10.1016/j.pharmthera.2019.05.016
Ronkina, N, Shushakova, N, Tiedje, C, Yakovleva, T, Tollenaere, MAX, Scott, A, Batth, TS, Olsen, JV, Helmke, A, Bekker-jensen, SH, Clark, AR, Kotlyarov, A & Gaestel, M 2019, 'The role of TTP phosphorylation in the regulation of inflammatory cytokine production by MK2/3', Journal of Immunology, vol. 203, no. 8, pp. 2291-2300. https://doi.org/10.4049/jimmunol.1801221
Abstract
Barney, K, Hagel, V, Clarke, J, Clark, AR, Abdelmottaleb, D, Raza, K, Anderson, A, Wraith, D & Scheel-Toellner, D 2023, 'Generation of a B Cell Model to Investigate the Function of FcRL4 in the Context of RA', British Society for Immunology Congress 2023, Belfast, United Kingdom, 4/12/23 - 7/12/23.
Review article
Clayton, SA, MacDonald, L, Kurowska-Stolarska, M & Clark, AR 2021, 'Mitochondria as key players in the pathogenesis and treatment of rheumatoid arthritis', Frontiers in immunology, vol. 12, 673916. https://doi.org/10.3389/fimmu.2021.673916
Crowley, T, Buckley, C & Clark, A 2018, 'Stroma: the forgotten cells of innate immune memory', Clinical & Experimental Immunology, vol. 193, no. 1, pp. 24-36. https://doi.org/10.1111/cei.13149
Falconer, J, Young, S, Clark, A & Buckley, C 2018, 'Synovial cell metabolism and chronic inflammation in rheumatoid arthritis', Arthritis and Rheumatology, vol. 70, no. 7, pp. 984-999. https://doi.org/10.1002/art.40504
Clayton, SA, Jones, SW, Kurowska-stolarska, M & Clark, AR 2018, 'The role of microRNAs in glucocorticoid action', Journal of Biological Chemistry, vol. 293, no. 6, pp. 1865-1874. https://doi.org/10.1074/jbc.R117.000366
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