Recent publications
Article
Quarton, S, McGee, K, Cumley, N, Behruznia, M, Jeff, C, Belchamber, K, Cox, M, Thickett, D, Scott, A, Parekh, D, McNally, A & Sapey, E 2024, 'Towards personalised anti-microbial and immune approaches to infections in acute care. Can real-time genomic-informed diagnosis of pathogens, and immune-focused therapies improve outcomes for patients? An observational, experimental study protocol', PLoS ONE, vol. 19, no. 3, e0298425. https://doi.org/10.1371/journal.pone.0298425
Belchamber, KBR, Thein, OS, Hazeldine, J, Grudzinska, FS, Faniyi, A, Hughes, M, Jasper, A, Yip, KP, Crowley, LE, Lugg, ST, Sapey, E, Parekh, D, Thickett, DR & Scott, A 2022, 'Dysregulated neutrophil phenotype and function in hospitalised non-ICU COVID-19 pneumonia', Cells, vol. 11, no. 18, 2901. https://doi.org/10.3390/cells11182901
Lodge, KM, Vassallo, A, Liu, B, Long, M, Tong, Z, Newby, PR, Agha-Jaffa, D, Paschalaki, K, Green, CE, Belchamber, KBR, Ridger, VC, Stockley, RA, Sapey, E, Summers, C, Cowburn, AS, Chilvers, ER, Li, W & Condliffe, AM 2022, 'Hypoxia Increases the Potential for Neutrophil-mediated Endothelial Damage in Chronic Obstructive Pulmonary Disease', American Journal of Respiratory and Critical Care Medicine, vol. 205, no. 8, pp. 903-916. https://doi.org/10.1164/rccm.202006-2467OC
Mahida, RY, Scott, A, Parekh, D, Lugg, ST, Belchamber, KBR, Hardy, RS, Matthay, MA, Naidu, B & Thickett, DR 2021, 'Assessment of Alveolar Macrophage Dysfunction Using an in vitro Model of Acute Respiratory Distress Syndrome', Frontiers in Medicine, vol. 8, 737859. https://doi.org/10.3389/fmed.2021.737859
Walker, EM, Jasper, AE, Davis, L, Yip, KP, Faniyi, AA, Hughes, MJ, Crisford, HA, Spittle, DA, Sapey, E, Belchamber, KBR & Scott, A 2020, 'Mitigating health risks to reopen a clinical research laboratory during the COVID-19 pandemic: a framework', JMIR Research Protocols, vol. 9, no. 12, e22570. https://doi.org/10.2196/22570
Belchamber, KBR & COPDMAP consortium 2019, 'Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages', The European respiratory journal, vol. 54, no. 4, 1802244. https://doi.org/10.1183/13993003.02244-2018
Finney, LJ, Belchamber, KBR, Fenwick, PS, Kemp, SV, Edwards, MR, Mallia, P, Donaldson, G, Johnston, SL, Donnelly, LE & Wedzicha, JA 2019, 'Human rhinovirus impairs the innate immune response to bacteria in alveolar macrophages in chronic obstructive pulmonary disease', American Journal of Respiratory and Critical Care Medicine, vol. 199, no. 12, pp. 1496-1507. https://doi.org/10.1164/rccm.201806-1095OC
Belchamber, K, Thomas, CM, Dunne, AE, Barnes, PJ & Donnelly, LE 2018, 'Comparison of fluticasone propionate and budesonide on COPD macrophage and neutrophil function', International journal of chronic obstructive pulmonary disease, vol. 13, pp. 2883-2897. https://doi.org/10.2147/COPD.S169337
Abstract
Belchamber, K, Thein, S, Hazeldine, J, Grudzinska, F, Hughes, M, Jasper, A, Yip, KP, Parekh, D, Sapey, E, Thickett, D & Scott, A 2021, 'Late Breaking Abstract - Elevated NETosis and migration but impaired anti-microbial responses by COVID-19 neutrophils', European Respiratory Journal, vol. 58, no. suppl 65, OA3974. https://doi.org/10.1183/13993003.congress-2021.OA3974
Belchamber, K, Thein, S, Hazeldine, J, Grudzinska, F, Jasper, A, Hughes, M, Yip, KP, Sapey, E, Parekh, D, Thickett, D & Scott, A 2021, 'S54 Elevated NETosis and migration but impaired anti-microbial responses in neutrophils from non-ICU, hospitalized COVID-19 patients', Thorax, vol. 76, no. Suppl 2, pp. A37. https://doi.org/10.1136/thorax-2021-btsabstracts.60
Preprint
Belchamber, K, Thein, O, Hazeldine, J, Grudzinska, F, Hughes, M, Jasper, A, Yip, KP, Sapey, E, Parekh, D, Thickett, D & Scott, A 2021 'Altered neutrophil phenotype and function in non-ICU hospitalised COVID-19 patients correlated with disease severity' medRxiv. https://doi.org/10.1101/2021.06.08.21258535
Walker, EM, Jasper, AE, Davis, L, Yip, KP, Faniyi, AA, Hughes, MJ, Crisford, HA, Spittle, DA, Sapey, E, Belchamber, KBR & Scott, A 2020 'Mitigating health risks to reopen a clinical research laboratory during the COVID-19 pandemic: a framework ' JMIR Publications. https://doi.org/10.2196/preprints.22570
Review article
Faniyi, AA, Hughes, MJ, Scott, A, Belchamber, KBR & Sapey, E 2021, 'Inflammation, ageing and diseases of the lung: Potential therapeutic strategies from shared biological pathways', British Journal of Pharmacology. https://doi.org/10.1111/bph.15759
Belchamber, KBR, Hughes, MJ, Spittle, DA, Walker, EM & Sapey, E 2021, 'New Pharmacological Tools to Target Leukocyte Trafficking in Lung Disease', Frontiers in immunology, vol. 12, 704173. https://doi.org/10.3389/fimmu.2021.704173
Belchamber, KBR, Walker, EM, Stockley, RA & Sapey, E 2020, 'Monocytes and macrophages in alpha-1 antitrypsin deficiency', International Journal of COPD, vol. 15, pp. 3183-3192. https://doi.org/10.2147/COPD.S276792
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