Recent publications
Article
Thein, OS, Belchamber, K, Hazeldine, J, Faniyi, A, Grudzinska, F, Hughes, M, Jasper, A, Yip, KP, Crowley, L, Lugg, S, Sapey, E, Parekh, D, Thickett, D & Scott, A 2024, 'Dysfunctional neutrophil response in COVID-19 infection vary by subtype', Clinical Medicine, Journal of the Royal College of Physicians of London, vol. 23, no. 6, pp. 69-70. https://doi.org/10.7861/clinmed.23-6-s69
Grudzinska, F, Faniyi, AA, Belchamber, KBR, Chen, C, Stockley, R, Jasper, A, Parekh, D, Sapey, E, Scott, A & Thickett, DR 2025, 'Hospitalised older adults with community-acquired pneumonia and sepsis have dysregulated neutrophil function but preserved glycolysis', Thorax, vol. 80, no. 2, pp. 97-104. https://doi.org/10.1136/thorax-2024-222215
Quarton, S, McGee, K, Cumley, N, Behruznia, M, Jeff, C, Belchamber, K, Cox, M, Thickett, D, Scott, A, Parekh, D, McNally, A & Sapey, E 2024, 'Towards personalised anti-microbial and immune approaches to infections in acute care. Can real-time genomic-informed diagnosis of pathogens, and immune-focused therapies improve outcomes for patients? An observational, experimental study protocol', PLoS ONE, vol. 19, no. 3, e0298425. https://doi.org/10.1371/journal.pone.0298425
Belchamber, KBR, Thein, OS, Hazeldine, J, Grudzinska, FS, Faniyi, A, Hughes, M, Jasper, A, Yip, KP, Crowley, LE, Lugg, ST, Sapey, E, Parekh, D, Thickett, DR & Scott, A 2022, 'Dysregulated neutrophil phenotype and function in hospitalised non-ICU COVID-19 pneumonia', Cells, vol. 11, no. 18, 2901. https://doi.org/10.3390/cells11182901
Lodge, KM, Vassallo, A, Liu, B, Long, M, Tong, Z, Newby, PR, Agha-Jaffa, D, Paschalaki, K, Green, CE, Belchamber, KBR, Ridger, VC, Stockley, RA, Sapey, E, Summers, C, Cowburn, AS, Chilvers, ER, Li, W & Condliffe, AM 2022, 'Hypoxia Increases the Potential for Neutrophil-mediated Endothelial Damage in Chronic Obstructive Pulmonary Disease', American Journal of Respiratory and Critical Care Medicine, vol. 205, no. 8, pp. 903-916. https://doi.org/10.1164/rccm.202006-2467OC
Mahida, RY, Scott, A, Parekh, D, Lugg, ST, Belchamber, KBR, Hardy, RS, Matthay, MA, Naidu, B & Thickett, DR 2021, 'Assessment of Alveolar Macrophage Dysfunction Using an in vitro Model of Acute Respiratory Distress Syndrome', Frontiers in Medicine, vol. 8, 737859. https://doi.org/10.3389/fmed.2021.737859
Walker, EM, Jasper, AE, Davis, L, Yip, KP, Faniyi, AA, Hughes, MJ, Crisford, HA, Spittle, DA, Sapey, E, Belchamber, KBR & Scott, A 2020, 'Mitigating health risks to reopen a clinical research laboratory during the COVID-19 pandemic: a framework', JMIR Research Protocols, vol. 9, no. 12, e22570. https://doi.org/10.2196/22570
Abstract
Belchamber, K, Thein, S, Hazeldine, J, Grudzinska, F, Hughes, M, Jasper, A, Yip, KP, Parekh, D, Sapey, E, Thickett, D & Scott, A 2021, 'Late Breaking Abstract - Elevated NETosis and migration but impaired anti-microbial responses by COVID-19 neutrophils', European Respiratory Journal, vol. 58, no. suppl 65, OA3974. https://doi.org/10.1183/13993003.congress-2021.OA3974
Belchamber, K, Thein, S, Hazeldine, J, Grudzinska, F, Jasper, A, Hughes, M, Yip, KP, Sapey, E, Parekh, D, Thickett, D & Scott, A 2021, 'S54 Elevated NETosis and migration but impaired anti-microbial responses in neutrophils from non-ICU, hospitalized COVID-19 patients', Thorax, vol. 76, no. Suppl 2, pp. A37. https://doi.org/10.1136/thorax-2021-btsabstracts.60
Preprint
Belchamber, K, Thein, O, Hazeldine, J, Grudzinska, F, Hughes, M, Jasper, A, Yip, KP, Sapey, E, Parekh, D, Thickett, D & Scott, A 2021 'Altered neutrophil phenotype and function in non-ICU hospitalised COVID-19 patients correlated with disease severity' medRxiv. https://doi.org/10.1101/2021.06.08.21258535
Walker, EM, Jasper, AE, Davis, L, Yip, KP, Faniyi, AA, Hughes, MJ, Crisford, HA, Spittle, DA, Sapey, E, Belchamber, KBR & Scott, A 2020 'Mitigating health risks to reopen a clinical research laboratory during the COVID-19 pandemic: a framework ' JMIR Publications. https://doi.org/10.2196/preprints.22570
Review article
Sandhu, KK, Scott, A, Tatler, AL, Belchamber, KBR & Cox, MJ 2024, 'Macrophages and the microbiome in chronic obstructive pulmonary disease', European Respiratory Review, vol. 33, no. 174, 240053. https://doi.org/10.1183/16000617.0053-2024
Faniyi, AA, Hughes, MJ, Scott, A, Belchamber, KBR & Sapey, E 2021, 'Inflammation, ageing and diseases of the lung: Potential therapeutic strategies from shared biological pathways', British Journal of Pharmacology. https://doi.org/10.1111/bph.15759
Belchamber, KBR, Hughes, MJ, Spittle, DA, Walker, EM & Sapey, E 2021, 'New Pharmacological Tools to Target Leukocyte Trafficking in Lung Disease', Frontiers in immunology, vol. 12, 704173. https://doi.org/10.3389/fimmu.2021.704173
Belchamber, KBR, Walker, EM, Stockley, RA & Sapey, E 2020, 'Monocytes and macrophages in alpha-1 antitrypsin deficiency', International Journal of COPD, vol. 15, pp. 3183-3192. https://doi.org/10.2147/COPD.S276792
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