Recent publications
Article
Chew, YH & Spill, F 2024, 'Discretised Flux Balance Analysis for Reaction–Diffusion Simulation of Single-Cell Metabolism', Bulletin of Mathematical Biology, vol. 86, no. 4, 39. https://doi.org/10.1007/s11538-024-01264-6
Chew, YH 2022, 'The Arabidopsis Framework Model version 2 predicts the organism-level effects of circadian clock gene mis-regulation', in silico Plants.
Goldberg, AP, Szigeti, B, Chew, YH, Sekar, JA, Roth, YD & Karr, JR 2018, 'Emerging whole-cell modeling principles and methods', Current Opinion in Biotechnology. https://doi.org/10.1016/j.copbio.2017.12.013
Chew, YH, Seaton, DD & Millar, AJ 2017, 'Multi-scale modelling to synergise Plant Systems Biology and Crop Science', Field Crops Research. https://doi.org/10.1016/j.fcr.2016.02.012
Waltemath, D, Karr, JR, Bergmann, FT, Chelliah, V, Hucka, M, Krantz, M, Liebermeister, W, Mendes, P, Myers, CJ, Pir, P, Alaybeyoglu, B, Aranganathan, NK, Baghalian, K, Bittig, AT, Burke, PEP, Cantarelli, M, Chew, YH, Costa, RS, Cursons, J, Czauderna, T, Goldberg, AP, Gomez, HF, Hahn, J, Hameri, T, Gardiol, DFH, Kazakiewicz, D, Kiselev, I, Knight-Schrijver, V, Knupfer, C, Konig, M, Lee, D, Lloret-Villas, A, Mandrik, N, Medley, JK, Moreau, B, Naderi-Meshkin, H, Palaniappan, SK, Priego-Espinosa, D, Scharm, M, Sharma, M, Smallbone, K, Stanford, NJ, Song, J-H, Theile, T, Tokic, M, Tomar, N, Toure, V, Uhlendorf, J, Varusai, TM, Watanabe, LH, Wendland, F, Wolfien, M, Yurkovich, JT, Zhu, Y, Zardilis, A, Zhukova, A & Schreiber, F 2016, 'Toward Community Standards and Software for Whole-Cell Modeling', IEEE Transactions on Biomedical Engineering. https://doi.org/10.1109/TBME.2016.2560762
Chew, YH, Wenden, B, Flis, A, Mengin, V, Taylor, J, Davey, CL, Tindal, C, Thomas, H, Ougham, HJ, De Reffye, P, Stitt, M, Williams, M, Muetzelfeldt, R, Halliday, KJ & Millar, AJ 2015, 'Correction: Multiscale digital Arabidopsis predicts individual organ and whole-organism growth (Proc Natl Acad Sci USA (2014) 111 (E4127-E4136))', Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.1506983112
Chew, YH, Smith, RW, Jones, HJ, Seaton, DD, Grima, R & Halliday, KJ 2014, 'Mathematical Models Light Up Plant Signaling', The Plant Cell. https://doi.org/10.1105/TPC.113.120006
Chew, YH, Wenden, B, Flis, A, Mengin, V, Taylor, J, Davey, CL, Tindal, C, Thomas, H, Ougham, HJ, De Reffye, P, Stitt, M, Williams, M, Muetzelfeldt, R, Halliday, KJ & Millar, AJ 2014, 'Multiscale digital Arabidopsis predicts individual organ and whole-organism growth', Proceedings of the National Academy of Sciences of the United States of America. https://doi.org/10.1073/pnas.1410238111
Chew, YH, Wilczek, AM, Williams, M, Welch, SM, Schmitt, J & Halliday, KJ 2012, 'An augmented Arabidopsis phenology model reveals seasonal temperature control of flowering time', New Phytologist. https://doi.org/10.1111/j.1469-8137.2012.04069.x
Chew, YH & Halliday, KJ 2011, 'A stress-free walk from Arabidopsis to crops', Current Opinion in Biotechnology. https://doi.org/10.1016/j.copbio.2010.11.011
Chew, YH, Shia, YL, Lee, CT, Majid, FAA, Chua, LS, Sarmidi, MR & Aziz, RA 2009, 'Modeling of glucose regulation and insulin-signaling pathways', Molecular and Cellular Endocrinology. https://doi.org/10.1016/j.mce.2009.01.018
Chapter (peer-reviewed)
Chew, YH & Marucci, L 2024, Mechanistic Model-Driven Biodesign in Mammalian Synthetic Biology. in F Ceroni & K Polizzi (eds), Mammalian Synthetic Systems. Methods in Molecular Biology, vol. 2774, Humana Press, New York, pp. 71–84. https://doi.org/10.1007/978-1-0716-3718-0_6
Conference contribution
Goldberg, AP, Chew, YH & Karr, JR 2016, Toward scalable whole-cell modeling of human cells. in SIGSIM-PADS 2016 - Proceedings of the 2016 Annual ACM Conference on Principles of Advanced Discrete Simulation. https://doi.org/10.1145/2901378.2901402
Other contribution
Chew, YH, Seaton, DD, Mengin, V, Flis, A, Mugford, ST, Smith, AM, Stitt, M & Millar, AJ 2017, Linking circadian time to growth rate quantitatively via carbon metabolism.. https://doi.org/10.1101/105437
Review article
Chew, YH & Karr, JR 2021, 'Centralizing data to unlock whole-cell models', Current Opinion in Systems Biology, vol. 27, 100353. https://doi.org/10.1016/j.coisb.2021.06.004
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