New NoriZite™ Nasal Spray launches in the UK

Award-winning innovation from Birmingham Biotech Ltd and University of Birmingham is now available in the UK

Norizite box, and bottles

Norizite™ Nasal Spray creates a barrier in the nose to trap viruses. The powerful anti-viral formula remains in the nose for six hours after application.

Birmingham Biotech Ltd, an innovator in diagnostic tests, protective nasal sprays and mobile medical facilities, today announces that NoriZite™ Nasal Spray, an easy-to-use nasal device designed to block and trap inhaled virus particles, is now available to buy in the UK.

The unique formulation was developed by the Healthcare Technologies Institute at the University of Birmingham, and won the “Materials Innovation Award 2022” at the Med-Tech Innovation Awards on 8th June this year.

NoriZite™ Nasal Spray coats the nasal cavity and creates a strong barrier to physically trap viruses and help remove them from the nose before they can cause infection.

NoriZite™ Nasal Spray combines powerful ingredients with a finely balanced viscosity to provide maximum surface coverage and long-lasting protection. The formula has been engineered to ‘plume’ rather than ‘jet’ when applied with a typical nasal spray applicator, offering up to six times more surface coverage than other nasal sprays on the market1.

NoriZite™ contains two main ingredients: carrageenan, an antiviral agent known for inhibiting infection against several respiratory viruses2, and gellan gum, which ensures effective coverage and retention in the nasal cavity. Both are polysaccharides that coat and retain virus particles so they do not infect local cells.

Laboratory studies have shown that the NoriZite™ formulation can prevent infection of cells (in culture) with SARS-CoV-2. The research confirmed the complete inhibition of SARS-CoV-2 infection for up to 48 hours in cells exposed to the carrageenan/gellan blend.1

The formulation not only provides extensive coverage of the nasal cavity, but its sticking power is long-lasting, and studies show it is retained in the nasal passage for at least six hours after application, outperforming many other standard nasal sprays on the market.3

Professor Liam Grover from the Healthcare Technologies Institute commented: “The formulation has been selected for its muco-adhesive properties – the ability to stick to the layer of mucous on the cells in the nasal passages. Its carefully formulated viscosity provides high surface coverage and long-lasting retention, helping it to stay in the nose rather than dripping out.”

Michael Hsu, Managing Director at Birmingham Biotech, commented: “We have seen huge success with NoriZite™ in other parts of the world since launching earlier this year. The long-lasting gel-like barrier is designed to trap airborne virus particles before they have the chance to cause infection. Our carefully balanced combination of powerful ingredients offers an additional layer of protection to support people as they live their new normal.”

 

Notes for editors

  • For media enquiries please contact Beck Lockwood, Press Office, University of Birmingham, tel: +44 (0)781 3343348.
  • The University of Birmingham is ranked amongst the world’s top 100 institutions. Its work brings people from across the world to Birmingham, including researchers, teachers and more than 6,500 international students from over 150 countries.
  • Birmingham Biotech is an innovator in diagnostic tests and protective nasal and throat sprays for medical conditions with an urgent, unmet need. In partnership with the University of Birmingham, Birmingham Biotech is committed to ensuring that patients in developing countries have access to the latest high-quality, affordable healthcare delivered through its rapid global supply chain. Birmingham Biotech is trusted by governments and healthcare providers around the world as a one-stop-shop for tests, equipment and consumables approved and recognised by international regulators.

References:

  1. Moakes, R. et al. Formulation of a Composite Nasal Spray Enabling Enhanced Surface Coverage and Prophylaxis of SARS-COV-2. Advanced Materials. 2021. 33(26), 2008304.
  2. Koenighofer, M. et al., Carrageenan nasal spray in virus confirmed common cold: individual patient data analysis of two randomized controlled trials. Multidisciplinary Respiratory Medicine 9, 57.
  3. Nasal Swab samples analysed by high performance liquid chromatography (HPLC) coupled UV-Vis spectroscopy - study conducted by LabWide Solutions HK Ltd.