Selected publications

Recent publications supported by the Cellular Health and Metabolism Facility 

1. 1. Frances S. Grudzinska, Alice Jasper, Elizabeth Sape, David R. Thickett, Claudio Mauro, Aaron Scott, Jonathan Barlow. (2023). Real-time assessment of neutrophil metabolism and oxidative burst using Extracellular Flux Analysis. Frontiers in Immunology.
   2. Congxin Sun et al. (2023). NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency. Cell Reports.
   3. Stavrou V, Fultang L, Booth S, De Simone D, Bartnik A, Scarpa U, Gneo L, Panetti S, Potluri S, Almowaled M, Barlow J, Jankevics A, Lloyd G, Southam A, Priestman DA, Cheng P, Dunn W, Platt F, Endou H, Craddock C, Keeshan K, Mussai F, De Santo C. (2023). Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment. Cancer Immunology, Immunotherapy.
   4. Silvia Panetti, Nicola McJannet, Livingstone Fultang, Sarah Booth, Luciana Gneo, Ugo Scarpa, Charles Smith, Ashley Vardon, Lisa Vettore, Celina Whalley, Yi Pan, Csilla Várnai, Hitoshi Endou, Jonathan Barlow, Daniel Tennant, Andrew Beggs, Francis Mussai, Carmela De Santo. (2022). Engineering amino acid uptake or catabolism promotes CAR-T cell adaption to the tumour environment. Blood Advances. 
   5. Allen SL, Seabright AP, Quinlan JI, Dhaliwal A, Williams FR, Fine NHF, Hodson DJ, Armstrong MJ, Elsharkaway AM, Greig CA, Lai YC, Lord JM, Lavery GG, Breen L. (2022). The Effect of Ex Vivo Human Serum from Liver Disease Patients on Cellular Protein Synthesis and Growth. Cell.
   6. Coltman NJ, Rochford G, Hodges NJ, Ali-Boucetta H, Barlow JP. (2022). Exploring Mitochondrial Energy Metabolism of Single 3D Microtissue Spheroids Using Extracellular Flux Analysis. Journal of Visualized Experiments (JoVE)
   7. Daniel G. Sadler, Marie M Phelan, Jonathan Barlow, Richard Draijer, Helen Jones, Dick H. J. Thijssen, Claire E. Stewart. (2022). Replicative ageing perturbs the metabolic signature of murine  C2C12 skeletal myotubes. BioRxiv.
   8. Daniel G. Sadler, Jonathan Barlow, Richard Draijer, Helen Jones, Dick H. J. Thijssen, and Claire E. Stewart. (2022). (–)-Epicatechin Alters Reactive Oxygen and Nitrogen Species Production Independent of Mitochondrial Respiration in Human Vascular Endothelial Cells. Oxidative Medicine and Cellular Longevity.
   9. Daniela Nasteska, Federica Cuozzo, Katrina Viloria, Elspeth M Johnson, Alpesh Thakker, Rula Bany Bakar, Rebecca L Westbrook, Jonathan P Barlow, Monica Hoang, Jamie W Joseph, Gareth G Lavery, Ildem Akerman, James Cantley, Leanne Hodson, Daniel A Tennant, David J Hodson. (2021). Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice. JCI Insight. 
   10. Barlow JP, Karstoft K, Vigelsø A, Gram M, Helge JW, Dela F, Pappan K, O'Neil D, Dunn W, Solomon TPJ. (2020). Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism. Metabolism Open.
   11. Alex P. Seabright., Nicholas H. F. Fine., Jonathan P. Barlow., et al. (2020). AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner. FASEB.
   12. Barlow, J. and Solomon, T. (2019). Conditioned media from contracting skeletal muscle potentiates insulin secretion and enhances mitochondrial energy metabolism of pancreatic beta-cells. Metabolism Clinical and Experimental.