Recent publications
Article
Bruque, M, Alison, R, Vrønning Hoffmann, S, Jones, N, Aucamp, J, Dafforn, T & Thomas, O 2024, 'Analysis of the Structure of 14 Therapeutic Antibodies Using Circular Dichroism Spectroscopy', Analytical Chemistry, vol. 96, no. 38, pp. 15151-15159. https://doi.org/10.1021/acs.analchem.4c01882
Wang, X, Slater, A, Lee, SC, Harrison, N, Pollock, NL, Bakker, SE, Navarro, S, Nieswandt, B, Dafforn, TR, García, Á, Watson, SP & Tomlinson, MG 2024, 'Purification and characterisation of the platelet-activating GPVI/FcRγ complex in SMALPs', Archives of Biochemistry and Biophysics, vol. 754, 109944. https://doi.org/10.1016/j.abb.2024.109944
Li, HZ, Pike, ACW, Lotsaris, I, Chi, G, Hansen, JS, Lee, SC, Rödström, KEJ, Bushell, SR, Speedman, D, Evans, A, Wang, D, He, D, Shrestha, L, Nasrallah, C, Burgess-Brown, NA, Vandenberg, RJ, Dafforn, TR, Carpenter, EP & Sauer, DB 2024, 'Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2', Nature Communications, vol. 15, no. 1, 5503. https://doi.org/10.1038/s41467-024-48921-x
Cioccolo, S, Barritt, JD, Pollock, N, Hall, Z, Babuta, J, Sridhar, P, Just, A, Morgner, N, Dafforn, T, Gould, I & Byrne, B 2024, 'The mycobacterium lipid transporter MmpL3 is dimeric in detergent solution, SMALPs and reconstituted nanodiscs', RSC Chemical Biology. https://doi.org/10.1039/d4cb00110a
Harrison, N, Richardson, L, Pallini, C, Morano, I, Jinks, E, Cowley, J, Chan, H, Hill, HJ, Tuekprakhon, A, Li, Z, Matas de las Heras, C, Teodosio, A, Lavado, AS, Moring, R, Ashraf, A, Dafforn, TR, Grammatopoulos, DK, Gordon, J, Brady, CA, Young, LS, Barnes, NM, Stamataki, Z & Qureshi, OS 2023, 'A cell-based, SARS-CoV-2 spike protein interaction assay to inform the neutralising capacity of recombinant and patient sera antibodies', Frontiers in Virology, vol. 3, 1163385. https://doi.org/10.3389/fviro.2023.1163385
Little, HA, Ali, A, Carter, JG, Hicks, MR, Dafforn, TR & Tucker, JHR 2023, 'A plug-and-play aptamer diagnostic platform based on linear dichroism spectroscopy', Frontiers in Chemistry, vol. 11, 1040873. https://doi.org/10.3389/fchem.2023.1040873
Martin, A, Jemmett, P, Howitt, T, Wood, M, Burley, A, Cox, L, Dafforn, T, Welbourn, R, Campana, M, Skoda, MWA, Thompson, J, Hussain, H, Rawle, JL, Carla, F, Nicklin, CL, Arnold, T & Horswell, SL 2023, 'Effect of anionic lipids on mammalian plasma cell membrane properties', Langmuir, vol. 39, no. 7, pp. 2676-2691. https://doi.org/10.1021/acs.langmuir.2c03161
Pollock, NL, Lloyd, J, Montinaro, C, Rai, M & Dafforn, TR 2022, 'Conformational trapping of an ABC transporter in polymer lipid nanoparticles', The Biochemical journal, vol. 479, no. 2, pp. 145-159. https://doi.org/10.1042/BCJ20210312
Jemmett, PN, Milan, DC, Nichols, RJ, Howitt, T, Martin, A, Arnold, T, Rawle, JL, Nicklin, CL, Dafforn, TR, Cox, LR & Horswell, SL 2022, 'Influence of the lipid backbone on electrochemical phase behavior', Langmuir, vol. 38, no. 46, pp. 14290-14301. https://doi.org/10.1021/acs.langmuir.2c02370
Grime, R, Logan, R, Nestorow, S, Sridhar, P, Edwards, PC, Tate, CG, Klumperman, B, Dafforn, T, Poyner, DR, Reeves, PJ & Wheatley, M 2021, 'Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles', Nanoscale, vol. 13, no. 31, pp. 13519-13528. https://doi.org/10.1039/d1nr02419a
Vafaei, S, Allabush, F, Tabaei, SR, Male, L, Dafforn, TR, Tucker, JHR & Mendes, PM 2021, 'Förster resonance energy transfer nanoplatform based on recognition-induced fusion/fission of DNA mixed micelles for nucleic acid sensing', ACS Nano, vol. 15, no. 5, pp. 8517-8524. https://doi.org/10.1021/acsnano.1c00156
Carter, JG, Pfukwa, R, Riley, L, Tucker, JHR, Rodger, A, Dafforn, TR & Klumperman, B 2021, 'Linear dichroism activity of chiral poly(p-aryltriazole) foldamers', ACS Omega, vol. 6, no. 48, pp. 33231-33237. https://doi.org/10.1021/acsomega.1c06139
Hawkins, OP, Jahromi, CPT, Gulamhussein, AA, Nestorow, S, Bahra, T, Shelton, C, Owusu-mensah, QK, Mohiddin, N, O'rourke, H, Ajmal, M, Byrnes, K, Khan, M, Nahar, NN, Lim, A, Harris, C, Healy, H, Hasan, SW, Ahmed, A, Evans, L, Vaitsopoulou, A, Akram, A, Williams, C, Binding, J, Thandi, RK, Joby, A, Guest, A, Tariq, MZ, Rasool, F, Cavanagh, L, Kang, S, Asparuhov, B, Jestin, A, Dafforn, TR, Simms, J, Bill, RM, Goddard, AD & Rothnie, AJ 2021, 'Membrane protein extraction and purification using partially-esterified SMA polymers', Biochimica et Biophysica Acta (BBA) - Biomembranes, vol. 1863, no. 12, 183758. https://doi.org/10.1016/j.bbamem.2021.183758
Patent
Tucker, J, Dafforn, T, Carter, J, Duprey, J-L, Orueta Iturbe, L & Hicks, MR Jun. 09 2022, Target RNA Detection, Patent No. WO2022117816A1.
Preprint
Harrison, N, Richardson, L, Pallini, C, Morano, I, Jinks, E, Cowley, J, Chan, H, Hill, HJ, Matas de las Heras, C, Teodosio, A, Lavado, AS, Dafforn, TR, Grammatopoulos, DK, Gordon, J, Brady, CA, Young, LS, Barnes, NM, Stamataki, Z & Qureshi, OS 2022 'A cell-based, spike protein binding assay highlights differences in antibody neutralising capacity for SARS-CoV-2 variants' bioRxiv. https://doi.org/10.1101/2022.06.24.496409
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