C-Stich

Cerclage Suture Type for an Insufficient Cervix and its effect on Health (C-STICH)

 

The C-STICH trial is now closed. Thank you to all our sites, participants and collaborators for their contribution. The result is published in the C-STICH NIHR report.

 

THE MAIN TRIAL FEATURES:

  • A multi-centre randomised controlled trial covering obstetrics and gynaecology centres nationwide.
  • Funded by the National Institute for Health Research Health Technology Assessment Programme (NIHR HTA).
  • Chief Investigator for C-Stich is Mr Philip Toozs-Hobson.
  • Birmingham Clinical Trials Unit (University of Birmingham) is the CTU from which C-Stich is coordinated, with Birmingham Women's & Children's NHS FT acting as Sponsor.
  • The target recruitment is 2050 patients by 30th June 2020.
  • Participating women will be randomly allocated to either a monofilament or braided suture.
  • The primary objective is to examine the effect of using a monofilament suture material compared with a braided suture material on pregnancy loss rate (defined as miscarriage, stillbirth, neonatal death in the first week of life) and neonatal mortality up to 7 days post-delivery in women presenting with an insufficient cervix and treated with cervical cerclage.

For the Trial Schema click here